Hip SurgeryQIP in hipNCT07591311
The Quadro-Iliac Plane (QIP) Block in Hip Surgery
An observational study of Hip Surgery and Hip Arthroplasty, run by San Giovanni di Dio Hospital at 2 sites in Italy.
Trial summary
The goal of this observational study is to learn about the effectiveness of different locoregional anesthesia techniques, particularly the Quadro-Iliac Plane (QIP) block, in patients undergoing hip surgery, including arthroplasty. Read more about this study
- Who is it for?
- Any age
- Conditions the study is for
- Hip Surgery, Hip Arthroplasty
- What is being tested?
- Fascia iliaca block (FIB)
- Type of treatment
- Surgery or procedure
- How many people
- 80 participants
- Where
- 2 sitesItaly
- Study dates
- 4 May 2026to Nov 2027
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Any age
- All sexes
- No healthy volunteers
- Child, Adult, Older adult
Study population: Patients undergoing hip arthroplasty surgery, either elective or for a proximal femoral fracture
Who may be able to join
- Age ≥ 18 years
- Patients undergoing hip surgery, either elective or for a proximal femoral fracture
- Expected postoperative hospital stay ≥ 24 hours
- ASA physical status I-III
- Neuraxial and/or locoregional anesthesia according to standard clinical practice
- Provision of informed consent to participate in the study
Who cannot join
- Absence of informed consent
- Contraindications to locoregional and/or spinal anesthesia
- Allergy to local anesthetic agents
- Cognitive impairment preventing reliable assessment of outcomes
- Coagulation disorders and/or platelet abnormalities
- Antiplatelet or anticoagulant therapy that contraindicates spinal anesthesia
- Presence of localized infection or sepsis at the sites to be treated
Trial locations and contacts
2 sites in 1 country. Contact the study team or a site near you to ask about taking part.
Italy2 sites, 2 recruiting
- Recruiting
Crotone Hospital
Crotone
Tommaso Sorrentino, MD, +393277038017, dr.sorrentinotommaso@gmail.com
- Recruiting
Crotone Hospital
Crotone
Tommaso Sorrentino, +393277038017, dr.sorrentinotommaso@gmail.com
About this study
Official title: The Effectiveness of the "Quadro-Iliac Plane Block" in Hip Surgery: A Prospective Observational Clinical Study
The goal of this observational study is to learn about the effectiveness of different locoregional anesthesia techniques, particularly the Quadro-Iliac Plane (QIP) block, in patients undergoing hip surgery, including arthroplasty. The main question it aims to answer is:
Does the QIP block improve postoperative recovery and pain control compared to other routinely used locoregional anesthesia techniques in patients undergoing hip surgery?
Participants undergoing hip surgery as part of their standard clinical care will receive one of the locoregional anesthesia techniques already in use at the hospital (including QIP block, fascia iliaca block, PENG block, or others, according to anesthesiologist choice). Postoperative outcomes will be collected prospectively, including quality of recovery (QoR-15 at 24 hours), pain scores at rest and during movement at predefined time points up to 48 hours, analgesic consumption, time to first analgesic request, time to mobilization, and occurrence of complications.
Read the detailed description
This prospective, observational, non-interventional clinical study will evaluate postoperative recovery and analgesic outcomes in adult patients undergoing hip surgery who receive locoregional anesthesia techniques already used in routine clinical practice.
The study focuses particularly on the Quadro-Iliac Plane (QIP) block, a recently introduced fascial plane block performed at the posterior-inferior aspect of the quadratus lumborum muscle near its insertion on the iliac crest. The QIP block will be assessed in comparison with other locoregional techniques routinely used for hip surgery, including fascia iliaca block, PENG block, sacral or lumbosacral erector spinae plane block, femoral nerve block, sciatic nerve block, lumbar plexus block, neuraxial anesthesia, or combinations of these techniques.
Patients will not be randomized, and the choice of anesthetic and analgesic technique will be made by the attending anesthesiologist according to standard clinical practice. All blocks will be ultrasound-guided and performed under aseptic conditions using approved local anesthetics. Standard perioperative monitoring, spinal anesthesia when appropriate, postoperative multimodal analgesia, and rescue analgesia will be provided according to institutional protocols.
The primary endpoint will be postoperative quality of recovery, assessed using the Quality of Recovery-15 score 24 hours after surgery. Secondary outcomes will include postoperative pain scores at rest and during movement at predefined time points up to 48 hours, patient satisfaction, total analgesic consumption, time to first rescue analgesic request, time to first mobilization, nausea and vomiting, antiemetic use, and block-related or postoperative adverse events. Safety monitoring will include immediate complications during block performance, early post-block complications, and delayed neurological symptoms assessed up to 7 days after surgery.
The study plans to include at least 40 patients, with a possible sample size of 40-80 cases, and an expected maximum study duration of 18 months.
- Conditions
- Hip Surgery, Hip Arthroplasty
- Being tested
- Fascia iliaca block (FIB)
- Keywords
- regional anesthesia, hip, hip fracture, QIP, hip arthroplasty
- Medical subject headings
- Hip Fractures
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Fascia iliaca block (FIB)Procedure or surgery
Fascia Iliaca Block
| Study group | Role | What they receive |
|---|---|---|
| QIP | Quadro-Iliac Plane Block Receives: Procedure: Fascia iliaca block (FIB) |
What is being measured
The primary outcome is the main question the study is designed to answer.
Quality of Recovery (QoR)-15 score
The Quality of Recovery-15 (QoR-15) is a validated patient-reported outcome measure designed to assess the quality of postoperative recovery across multiple dimensions of physical and psychological well-being.
The questionnaire consists of 15 items, each scored on an 11-point numerical scale, resulting in a total score ranging from:
Minimum score: 0 → extremely poor quality of recovery Maximum score: 150 → excellent quality of recovery
Higher QoR-15 scores indicate a better postoperative recovery experience.
The questionnaire evaluates five key domains:
Pain Physical comfort Physical independence Psychological support Emotional state
Measured: 24 hours postoperatively
Secondary outcomes (4)
Postoperative Pain
The Numerical Rating Scale (NRS) is a validated and widely used tool for the assessment of pain intensity in clinical practice and perioperative research.
Patients are asked to rate their pain on a numerical scale ranging from:
0 → no pain 10 → worst pain imaginable
Measured: 0-2-4-6-8-12-24-48 hours after surgery
First analgesia request
Duration of analgesia
Measured: up to 48 hours
First mobilization
First mobilization of the patient after surgery
Measured: 24 hours postoperatively
Complications
Toxicity, PONV, others
Measured: up to 48 hours
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted15 May 2026
- Study start4 May 2026
- Primary completionJun 2027 (estimated)
- Study completionNov 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Hip SurgeryStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 80 participants (estimated)
Sponsor and investigators
- Lead sponsor
- San Giovanni di Dio Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Tommaso Sorrentino, San Giovanni di Dio Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07591311
- Sponsor's protocol ID
- QIP_study
- Other IDs
- No other
- Acronym
- QIP in hip
- Status last verified
- Aug 2026
- First submitted
- 4 May 2026
- Last updated
- 2 Sep 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 2 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effectiveness of the "Quadro-Iliac Plane Block" in Hip Surgery: A Prospective Observational Clinical Study
- ClinicalTrials.gov ID
- NCT07591311
- Acronym / sponsor ID
- QIP in hip / QIP_study
- Conditions
- Hip Surgery, Hip Arthroplasty
- Keywords
- regional anesthesia, hip, hip fracture, QIP, hip arthroplasty
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 80 participants (estimated)
- Lead sponsor
- San Giovanni di Dio HospitalUniversity, hospital or other
- Study start
- 4 May 2026 (actual)
- Primary completion
- Jun 2027 (estimated)
- Study completion
- Nov 2027 (estimated)
- First posted
- 15 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this observational study is to learn about the effectiveness of different locoregional anesthesia techniques, particularly the Quadro-Iliac Plane (QIP) block, in patients undergoing hip surgery, including arthroplasty. The main question it aims to answer is:
Does the QIP block improve postoperative recovery and pain control compared to other routinely used locoregional anesthesia techniques in patients undergoing hip surgery?
Participants undergoing hip surgery as part of their standard clinical care will receive one of the locoregional anesthesia techniques already in use at the hospital (including QIP block, fascia iliaca block, PENG block, or others, according to anesthesiologist choice). Postoperative outcomes will be collected prospectively, including quality of recovery (QoR-15 at 24 hours), pain scores at rest and during movement at predefined time points up to 48 hours, analgesic consumption, time to first analgesic request, time to mobilization, and occurrence of complications.
Detailed description
This prospective, observational, non-interventional clinical study will evaluate postoperative recovery and analgesic outcomes in adult patients undergoing hip surgery who receive locoregional anesthesia techniques already used in routine clinical practice.
The study focuses particularly on the Quadro-Iliac Plane (QIP) block, a recently introduced fascial plane block performed at the posterior-inferior aspect of the quadratus lumborum muscle near its insertion on the iliac crest. The QIP block will be assessed in comparison with other locoregional techniques routinely used for hip surgery, including fascia iliaca block, PENG block, sacral or lumbosacral erector spinae plane block, femoral nerve block, sciatic nerve block, lumbar plexus block, neuraxial anesthesia, or combinations of these techniques.
Patients will not be randomized, and the choice of anesthetic and analgesic technique will be made by the attending anesthesiologist according to standard clinical practice. All blocks will be ultrasound-guided and performed under aseptic conditions using approved local anesthetics. Standard perioperative monitoring, spinal anesthesia when appropriate, postoperative multimodal analgesia, and rescue analgesia will be provided according to institutional protocols.
The primary endpoint will be postoperative quality of recovery, assessed using the Quality of Recovery-15 score 24 hours after surgery. Secondary outcomes will include postoperative pain scores at rest and during movement at predefined time points up to 48 hours, patient satisfaction, total analgesic consumption, time to first rescue analgesic request, time to first mobilization, nausea and vomiting, antiemetic use, and block-related or postoperative adverse events. Safety monitoring will include immediate complications during block performance, early post-block complications, and delayed neurological symptoms assessed up to 7 days after surgery.
The study plans to include at least 40 patients, with a possible sample size of 40-80 cases, and an expected maximum study duration of 18 months.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| QIP | – | Procedure: Fascia iliaca block (FIB)Quadro-Iliac Plane Block |
Who may qualify
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult, Older adult
- Study population
- Patients undergoing hip arthroplasty surgery, either elective or for a proximal femoral fracture
Key inclusion criteria (6 listed)
- Age ≥ 18 years
- Patients undergoing hip surgery, either elective or for a proximal femoral fracture
- Expected postoperative hospital stay ≥ 24 hours
- ASA physical status I-III
- Neuraxial and/or locoregional anesthesia according to standard clinical practice
Key exclusion criteria (7 listed)
- Absence of informed consent
- Contraindications to locoregional and/or spinal anesthesia
- Allergy to local anesthetic agents
- Cognitive impairment preventing reliable assessment of outcomes
- Coagulation disorders and/or platelet abnormalities
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Fascia iliaca block (FIB)Fascia Iliaca Block | Procedure or surgery | QIP |
Primary outcome
Quality of Recovery (QoR)-15 score
Time frame: 24 hours postoperatively
The Quality of Recovery-15 (QoR-15) is a validated patient-reported outcome measure designed to assess the quality of postoperative recovery across multiple dimensions of physical and psychological well-being. The questionnaire consists of 15 items, each scored on an 11-point numerical scale, resulting in a total score ranging from: Minimum score: 0 → extremely poor quality of recovery Maximum score: 150 → excellent quality of recovery Higher QoR-15 scores indicate a better postoperative recovery experience. The questionnaire evaluates five key domains: Pain Physical comfort Physical independence Psychological support Emotional state
4 secondary outcomes
Postoperative Pain
Time frame: 0-2-4-6-8-12-24-48 hours after surgery
First analgesia request
Time frame: up to 48 hours
First mobilization
Time frame: 24 hours postoperatively
Complications
Time frame: up to 48 hours
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 2 Sep 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
2 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Hip Surgery and Hip Arthroplasty, run by San Giovanni di Dio Hospital at 2 sites in Italy.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 2 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 2 sites in Italy. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Tommaso Sorrentino, MD (+393277038017, dr.sorrentinotommaso@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Quality of Recovery (QoR)-15 score (time frame: 24 hours postoperatively). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 2 Sep 2026.