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AzTrials

Periodontitis(MBL)NCT07608523

Marginal Bone Level Around Dental Implants in Periodontitis Patients

A study testing SLA Dental Implant and Plasma Spraying Dental Implant in people with Periodontitis and Dental Implants, run by Faculty of Dental Medicine for Girls at 1 site in Egypt.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record
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Trial summary

This study evaluates and compares marginal bone level changes around dental implants with two different surface characteristics in patients with a history of periodontitis. Participants will receive dental implants and will be followed up for one year to assess bone level changes around the implants. Read more about this study

Who is it for?
Ages 35 to 55 yearsHealthy volunteers can take part
Conditions the study is for
Periodontitis, Dental Implants, Marginal Bone Loss
What is being tested?
SLA Dental Implant and Plasma Spraying Dental Implant
Type of treatment
Medical device
Could I receive a placebo?
No, everyone receives an active treatment
How many people
40 participants
Where
1 siteEgypt
Study dates
30 Apr 2023to 30 Apr 2026
Phase
Interventional
Are there results?
None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 35 to 55 years
  • All sexes
  • Healthy volunteers accepted
  • Adult

Who may be able to join

  • Age ranged from 35 to 55 years old, with a history of periodontitis
  • Presence of at least one edentulous space
  • Presence of adequate bone volume to place implants and achieves primary implant stability without the need for bone reconstructive approaches
  • Absence of systemic diseases

Who cannot join

  • Presence of para-functional habits
  • Chronic smokers or former smokers
  • Pregnancy and lactation
  • Any patient who is not willing to follow our treatment protocol

Trial locations and contacts

1 site in 1 country.

Egypt1 site

  • Faculty of Dental Medicine for Girls, Al-Azhar University

    Cairo, Cairo Governorate

Other trials in Egypt

About this study

Official title: Evaluation of Marginal Bone Level Around Dental Implants With Two Types of Surface Characteristics in Periodontitis Patients

This study evaluates and compares marginal bone level changes around dental implants with two different surface characteristics in patients with a history of periodontitis. Participants will receive dental implants and will be followed up for one year to assess bone level changes around the implants.

Read the detailed description

Patients with treated periodontitis who require dental implants will be divided into two groups based on implant surface type. Marginal bone level will be assessed radiographically at baseline, then at 3 months,6 months, and 12 months after implant placement. The study aims to determine whether implant surface characteristics influence marginal bone loss in periodontitis-susceptible patients over a one-year follow-up period.

Being tested
SLA Dental Implant, Plasma Spraying Dental Implant
Keywords
SLA implant, Plasma spraying implant, Peri-implant bone, Periodontitis patients, Implant surface, Probing Depth, Gingival Index
Medical subject headings
Periodontitis, Gingivitis

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • SLA Dental ImplantDevice

    Sandblasted large-grit corundum and acid-etched (SLA) surface dental implant

  • Plasma Spraying Dental ImplantDevice

    Plasma spraying surface treated dental implant

Study groups in NCT07608523
Study groupRoleWhat they receive
Group I - Periodontitis SLAExperimental15 periodontitis patients receiving SLA surface implants
Receives: Device: SLA Dental Implant
Group II - Periodontitis PlasmaExperimental15 periodontitis patients receiving plasma spraying surface treated implants
Receives: Device: Plasma Spraying Dental Implant
Group III - Healthy SLAActive comparator5 periodontally healthy patients receiving SLA surface implants
Receives: Device: SLA Dental Implant
Group IV - Healthy PlasmaActive comparator5 periodontally healthy patients receiving plasma spraying surface treated implants
Receives: Device: Plasma Spraying Dental Implant

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Marginal Bone Level

    Radiographic assessment of marginal bone level changes around dental implants measured in millimeters using Cone Beam Computed Tomography (CBCT)

    Measured: Baseline, 3 months, 6 months, and 12 months after implant placement

Secondary outcomes (2)

  1. Probing Depth

    probing depth measured in millimeters around implants

    Measured: Baseline, 3 months, 6 months, and 12 months

  2. Gingival Index

    The gingival condition around the implants were evaluated using the Löe and Silness Gingival Index. A plastic periodontal probe were used to gently assess the gingival tissues at four surfaces per implant (mesial, buccal, distal, and lingual). Each surface was scored from 0 to 3 as follows:

    0 = Normal gingiva

    1. = Mild inflammation (slight change in color, slight edema, no bleeding on probing)
    2. = Moderate inflammation (redness, edema, bleeding on probing)
    3. = Severe inflammation (marked redness and edema, ulceration, spontaneous bleeding)

    Measured: Baseline, 3 months, 6 months, and 12 months

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted27 May 2026
  2. Study start30 Apr 2023
  3. Primary completion30 Apr 2025
  4. Study completion30 Apr 2026

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Treatment
Allocation
Non-randomised
Intervention model
Factorial
Model description
Participants will be divided into four groups based on implant surface type and periodontal status: Group I: 15 periodontitis patients receiving sandblasted large-grit corundum and acid-etched (SLA) surface implants. Group II: 15 periodontitis patients receiving plasma spraying surface treated implants. Group III: 5 periodontally healthy patients receiving sandblasted large-grit corundum and acid-etched (SLA) surface implants. Group IV: 5 periodontally healthy patients receiving plasma spraying surface treated implants. All groups will be followed up for 12 months to assess marginal bone level changes radiographically.
Masking
None (open label)
Enrolment
40 participants (actual)
IDs, dates and publications
ClinicalTrials.gov ID
NCT07608523
Sponsor's protocol ID
AZHAR-OMPDR_103_2i-2023
Acronym
(MBL)
Status last verified
Apr 2023
First submitted
20 May 2026
Last updated
16 Jun 2026
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No

Questions about this trial

What is this clinical trial studying?

A study testing SLA Dental Implant and Plasma Spraying Dental Implant in people with Periodontitis and Dental Implants, run by Faculty of Dental Medicine for Girls at 1 site in Egypt.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 4 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 16 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Marginal Bone Level (time frame: Baseline, 3 months, 6 months, and 12 months after implant placement). It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT07608523.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 16 Jun 2026.

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