Suicidal Thoughts and BehaviorsSTAMM-SNCT07610785
Standardized Adaptive Music Medicine for Suicidality
A study testing STAMM-S in people with Suicidal Thoughts and Behaviors, run by Stanford University at 1 site in United States.
Trial summary
The primary goal of this clinical trial is to test if music-based intervention (STAMM-S) works for individuals with suicidal thoughts or behaviors. The main questions it aims to answer are: Can implementing specific music to listen to for 20 minutes a day for 25 days improve suicidality? Can implementing education… Read more about this study
- Who is it for?
- Ages 14 to 35 years
- Conditions the study is for
- Suicidal Thoughts and Behaviors
- What is being tested?
- STAMM-S
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 28 participants
- Where
- 1 siteUnited States
- Study dates
- Jun 2026to May 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 14 to 35 years
- All sexes
- No healthy volunteers
- Child, Adult
Who may be able to join
- Age 14-35 years
- Suicidal ideation (C-SSRS categories 1-3 within the past month)
- normal sensitivity to music reward on the Barcelona Music Reward Questionnaire. Score >65
Who cannot join
- imminent or acute suicide risk (C-SSRS categories 4-5).
- Co-morbid substance use disorder.
- Co-morbid psychotic disorder.
- current participation in another trial
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site
Yuukis Hall - Stanford University
Palo Alto, California, 94304
Daniel L Bowling, PhD
About this study
The primary goal of this clinical trial is to test if music-based intervention (STAMM-S) works for individuals with suicidal thoughts or behaviors. The main questions it aims to answer are:
- Can implementing specific music to listen to for 20 minutes a day for 25 days improve suicidality?
- Can implementing education around the psychology of the medicine of music improve mental health outcomes?
Participants will:
- Listen to music given to them by the study team for 20 minutes a day for 25 days
- Receive musical psychoeducation on how to improve mood using music
- Conditions
- Suicidal Thoughts and Behaviors
- Being tested
- STAMM-S
- Keywords
- Suicidality, Music-based intervention, Music
- Medical subject headings
- Suicidal Ideation, Behavior
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
STAMM-SBehavioural
Participants will undergo the STAMM-S treatment, which involves music generated using machine learning to move to a more positive affect. They will also receive education on how to best use the music assigned to improve their mood.
| Study group | Role | What they receive |
|---|---|---|
| STAMM-S | Experimental | Participants receive musical psychoeducation and take a dose of 20 minutes of adaptive music per day for 25 days. Receives: Behavioral: STAMM-S |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in Suicidality via Beck Scale for Suicidal Ideation (BSS/BSSI) Score
A 19-item scale with each item scoring from 0-2 rating an individual's suicidal thoughts, intent, and ideation. The total score ranges from 0 to 38. A higher score indicates more intense suicidal ideation and a low score indicates less intense suicidal ideation.
Measured: Baseline, week 1, week 2, week 3, and post-trial interview (up to 25 days).
Change in Generalized Anxiety Disorder Status via Generalized Anxiety Disorder-7 (GAD-7) Score
A 7-item measure scaled 0-3 per item that measures symptoms of Generalized Anxiety Disorder. 0 would be no sign of anxiety and 3 would indicate high level of anxiety over the last two weeks.
Measured: Baseline, week 1, week 2, week 3, and post-trial interview (up to 25 days).
Change in Depression Status via Patient Health Questionnaire-9 (PHQ-9) Score
A 9-item questionnaire that measures symptoms of depression on a 0-3 scale over the last two weeks. 0 would indicate "not at all", 1 would indicate "several days", 2 would indicate "most of the days", and a 3 would indicate "nearly every day".
Measured: Baseline, week 1, week 2, week 3, and post-trial interview (up to 25 days).
Secondary outcomes (3)
Change in Music Listening Purpose via Healthy-Unhealthy Music Scale (HUMS) - Healthy Score
Participants respond to a 5-question survey. The scale ranges from 5 to 25. For the healthy scale, a higher rating means a healthier use of music.
Measured: Baseline, end of study (up to 25 days).
Change in Music Listening Purpose via Healthy-Unhealthy Music Scale (HUMS) - Unhealthy Score
Participants respond to an 8-question survey. The scale ranges 8 to 40. A higher rating for the unhealthy scale indicates a more maladaptive use of music.
Measured: Baseline, end of study (up to 25 days).
Acceptability Scale Score
A 7-question questionnaire on a scale of 0-7 covering the 7 core components on intervention acceptability, where a 0 would indicate total unacceptability and 7 would equal total acceptability. Single participant rating of 4 or greater will be interpreted as satisfactory acceptability.
Measured: At the end of the intervention (25 days after enrollment).
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted28 May 2026
- Study startJun 2026 (estimated)
- Primary completionMay 2027 (estimated)
- Study completionMay 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Suicidal Thoughts and BehaviorsStudies of the same condition, open and under way.
- More trials run by Stanford UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 28 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Stanford University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Daniel Bowling, Stanford University
- Investigators
- Daniel L. Bowling, PhD, Principal investigator, Stanford University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07610785
- Sponsor's protocol ID
- 86501
- Other IDs
- ECR-0-025-24
- Acronym
- STAMM-S
- Status last verified
- May 2026
- First submitted
- 20 May 2026
- Last updated
- 28 May 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 28 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Standardized Adaptive Music Medicine for Suicidality
- ClinicalTrials.gov ID
- NCT07610785
- Acronym / sponsor ID
- STAMM-S / 86501
- Conditions
- Suicidal Thoughts and Behaviors
- Keywords
- Suicidality, Music-based intervention, Music
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 28 participants (estimated)
- Lead sponsor
- Stanford UniversityUniversity, hospital or other
- Study start
- Jun 2026 (estimated)
- Primary completion
- May 2027 (estimated)
- Study completion
- May 2027 (estimated)
- First posted
- 28 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The primary goal of this clinical trial is to test if music-based intervention (STAMM-S) works for individuals with suicidal thoughts or behaviors. The main questions it aims to answer are:
- Can implementing specific music to listen to for 20 minutes a day for 25 days improve suicidality?
- Can implementing education around the psychology of the medicine of music improve mental health outcomes?
Participants will:
- Listen to music given to them by the study team for 20 minutes a day for 25 days
- Receive musical psychoeducation on how to improve mood using music
Study design
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| STAMM-S | Experimental | Behavioral: STAMM-SParticipants receive musical psychoeducation and take a dose of 20 minutes of adaptive music per day for 25 days. |
Who may qualify
- Ages
- 14 to 35 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult
Key inclusion criteria (3 listed)
- Age 14-35 years
- Suicidal ideation (C-SSRS categories 1-3 within the past month)
- normal sensitivity to music reward on the Barcelona Music Reward Questionnaire. Score >65
Key exclusion criteria (4 listed)
- imminent or acute suicide risk (C-SSRS categories 4-5).
- Co-morbid substance use disorder.
- Co-morbid psychotic disorder.
- current participation in another trial
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| STAMM-SParticipants will undergo the STAMM-S treatment, which involves music generated using machine learning to move to a more positive affect. They will also receive education on how to best use the music assigned to improve their mood. | Behavioural | STAMM-S |
Primary outcome
Change in Suicidality via Beck Scale for Suicidal Ideation (BSS/BSSI) Score
Time frame: Baseline, week 1, week 2, week 3, and post-trial interview (up to 25 days).
A 19-item scale with each item scoring from 0-2 rating an individual's suicidal thoughts, intent, and ideation. The total score ranges from 0 to 38. A higher score indicates more intense suicidal ideation and a low score indicates less intense suicidal ideation.
Change in Generalized Anxiety Disorder Status via Generalized Anxiety Disorder-7 (GAD-7) Score
Time frame: Baseline, week 1, week 2, week 3, and post-trial interview (up to 25 days).
A 7-item measure scaled 0-3 per item that measures symptoms of Generalized Anxiety Disorder. 0 would be no sign of anxiety and 3 would indicate high level of anxiety over the last two weeks.
Change in Depression Status via Patient Health Questionnaire-9 (PHQ-9) Score
Time frame: Baseline, week 1, week 2, week 3, and post-trial interview (up to 25 days).
A 9-item questionnaire that measures symptoms of depression on a 0-3 scale over the last two weeks. 0 would indicate "not at all", 1 would indicate "several days", 2 would indicate "most of the days", and a 3 would indicate "nearly every day".
3 secondary outcomes
Change in Music Listening Purpose via Healthy-Unhealthy Music Scale (HUMS) - Healthy Score
Time frame: Baseline, end of study (up to 25 days).
Change in Music Listening Purpose via Healthy-Unhealthy Music Scale (HUMS) - Unhealthy Score
Time frame: Baseline, end of study (up to 25 days).
Acceptability Scale Score
Time frame: At the end of the intervention (25 days after enrollment).
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 28 May 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Daniel L. Bowling, PhD principal investigator
Stanford University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing STAMM-S in people with Suicidal Thoughts and Behaviors, run by Stanford University at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 28 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in Suicidality via Beck Scale for Suicidal Ideation (BSS/BSSI) Score (time frame: Baseline, week 1, week 2, week 3, and post-trial interview (up to 25 days).). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 28 May 2026.