Nasal SurgeryNCT07622745
Nasal Surgery in Snoring and Obstructive Sleep Apnea
A study testing Septoplasty with partial inferior turbinectomy, Nasal polypectomy and Partial inferior turbinectomy in people with Nasal Surgery and Snoring, run by Al-Azhar University at 1 site in Egypt.
Trial summary
This study aimed to evaluate the effect of isolated nasal surgery on sleep-disordered breathing, particularly apnea-hypopnea index (AHI) and snoring index (SI), Apnea index (AI) and minimal arterial oxygen saturation (MAO2) in adults with obstructive sleep apnea syndrome (OSAS) and nasal obstruction. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Nasal Surgery, Snoring, Obstructive Sleep Apnea
- What is being tested?
- Septoplasty with partial inferior turbinectomy, Nasal polypectomy and Partial inferior turbinectomy
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 30 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Mar 2022to 1 Jul 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Age above 18 years.
- Both sexes.
- Patients with anatomical nasal obstruction due to septal deviation, hypertrophied inferior turbinate (HIT), or nasal polyps refractory to medical treatment.
- Presence of snoring and obstructive sleep apnea (OSA).
- Fitness for surgery.
Who cannot join
- Central or mixed sleep apnea.
- Previous nasal surgery.
- Unfitness for surgery.
- Pathological obesity.
- History of cardiopulmonary disease or asthma.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Role of Nasal Surgery in Snoring and Obstructive Sleep Apnea
This study aimed to evaluate the effect of isolated nasal surgery on sleep-disordered breathing, particularly apnea-hypopnea index (AHI) and snoring index (SI), Apnea index (AI) and minimal arterial oxygen saturation (MAO2) in adults with obstructive sleep apnea syndrome (OSAS) and nasal obstruction.
Read the detailed description
Snoring is the noisy breathing that occurs throughout sleep, resulting from the vibration of the structures in the oral cavity, including the soft palate, uvula, tonsils, base of the tongue, epiglottis, as well as pharyngeal walls.
Obstructive sleep apnea syndrome (OSAS) is a respiratory sleep disorder distinguished by repeated episodes of partial or total occlusion of the upper airways throughout sleep. This blockage is typically associated with a decrease (hypopnea) or total cessation (apnea) of airflow in the upper airways, and sustained thoracic-diaphragmatic respiratory movements.
- Conditions
- Nasal Surgery, Snoring, Obstructive Sleep Apnea
- Being tested
- Septoplasty with partial inferior turbinectomy, Nasal polypectomy, Partial inferior turbinectomy
- Medical subject headings
- Snoring, Sleep Apnea, Obstructive
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Septoplasty with partial inferior turbinectomyProcedure or surgery
Patients with nasal septal deviation and hypertrophied inferior turbinate (HIT) who underwent septoplasty with partial inferior turbinectomy.
Nasal polypectomyProcedure or surgery
Patients with chronic rhinosinusitis with nasal polyps who underwent functional endoscopic sinus surgery (FESS) with nasal polypectomy.
Partial inferior turbinectomyProcedure or surgery
Patients with isolated hypertrophied inferior turbinate (HIT) who underwent partial inferior turbinectomy alone.
| Study group | Role | What they receive |
|---|---|---|
| Group I | Experimental | Patients with nasal septal deviation and hypertrophied inferior turbinate (HIT) who underwent septoplasty with partial inferior turbinectomy. Receives: Procedure: Septoplasty with partial inferior turbinectomy |
| Group II | Experimental | Patients with chronic rhinosinusitis with nasal polyps who underwent functional endoscopic sinus surgery (FESS) with nasal polypectomy. Receives: Procedure: Nasal polypectomy |
| Group III | Experimental | Patients with isolated hypertrophied inferior turbinate (HIT) who underwent partial inferior turbinectomy alone. Receives: Procedure: Partial inferior turbinectomy |
What is being measured
The primary outcome is the main question the study is designed to answer.
Apnea-Hypopnea Index
The Apnea-Hypopnea Index (AHI) is a critical metric used to diagnose and rank the severity of sleep apnea. It measures the average number of times your breathing completely stops (apneas) or becomes severely shallow (hypopneas) per hour of sleep.
Measured: 3 months postoperatively
Secondary outcomes (1)
Snoring index
The snoring index was defined as the number of snoring episodes divided by the hours of total sleep time
Measured: 3 months postoperatively
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted3 Jun 2026
- Study start1 Mar 2022
- Primary completion1 Jul 2024
- Study completion1 Jul 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Nasal SurgeryStudies of the same condition, open and under way.
- More trials run by Al-Azhar UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 30 participants (actual)
Sponsor and investigators
- Lead sponsor
- Al-Azhar University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Asmaa Abdullah El Muhammady Ebrahim, Al-Azhar University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07622745
- Sponsor's protocol ID
- 1225
- Status last verified
- Jun 2026
- First submitted
- 23 May 2026
- Last updated
- 3 Jun 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: The data will be available upon a reasonable request from the corresponding author after the end of study for one year.
Study at a glance
From the registry record, last updated by the sponsor on 3 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Role of Nasal Surgery in Snoring and Obstructive Sleep Apnea
- ClinicalTrials.gov ID
- NCT07622745
- Acronym / sponsor ID
- 1225
- Conditions
- Nasal Surgery, Snoring, Obstructive Sleep Apnea
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 30 participants (actual)
- Lead sponsor
- Al-Azhar UniversityUniversity, hospital or other
- Study start
- 1 Mar 2022 (actual)
- Primary completion
- 1 Jul 2024 (actual)
- Study completion
- 1 Jul 2024 (actual)
- First posted
- 3 Jun 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aimed to evaluate the effect of isolated nasal surgery on sleep-disordered breathing, particularly apnea-hypopnea index (AHI) and snoring index (SI), Apnea index (AI) and minimal arterial oxygen saturation (MAO2) in adults with obstructive sleep apnea syndrome (OSAS) and nasal obstruction.
Detailed description
Snoring is the noisy breathing that occurs throughout sleep, resulting from the vibration of the structures in the oral cavity, including the soft palate, uvula, tonsils, base of the tongue, epiglottis, as well as pharyngeal walls.
Obstructive sleep apnea syndrome (OSAS) is a respiratory sleep disorder distinguished by repeated episodes of partial or total occlusion of the upper airways throughout sleep. This blockage is typically associated with a decrease (hypopnea) or total cessation (apnea) of airflow in the upper airways, and sustained thoracic-diaphragmatic respiratory movements.
Study design
- Primary purpose
- Treatment
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| Group I | Experimental | Procedure: Septoplasty with partial inferior turbinectomyPatients with nasal septal deviation and hypertrophied inferior turbinate (HIT) who underwent septoplasty with partial inferior turbinectomy. |
| Group II | Experimental | Procedure: Nasal polypectomyPatients with chronic rhinosinusitis with nasal polyps who underwent functional endoscopic sinus surgery (FESS) with nasal polypectomy. |
| Group III | Experimental | Procedure: Partial inferior turbinectomyPatients with isolated hypertrophied inferior turbinate (HIT) who underwent partial inferior turbinectomy alone. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (5 listed)
- Age above 18 years.
- Both sexes.
- Patients with anatomical nasal obstruction due to septal deviation, hypertrophied inferior turbinate (HIT), or nasal polyps refractory to medical treatment.
- Presence of snoring and obstructive sleep apnea (OSA).
- Fitness for surgery.
Key exclusion criteria (5 listed)
- Central or mixed sleep apnea.
- Previous nasal surgery.
- Unfitness for surgery.
- Pathological obesity.
- History of cardiopulmonary disease or asthma.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Septoplasty with partial inferior turbinectomyPatients with nasal septal deviation and hypertrophied inferior turbinate (HIT) who underwent septoplasty with partial inferior turbinectomy. | Procedure or surgery | Group I |
| Nasal polypectomyPatients with chronic rhinosinusitis with nasal polyps who underwent functional endoscopic sinus surgery (FESS) with nasal polypectomy. | Procedure or surgery | Group II |
| Partial inferior turbinectomyPatients with isolated hypertrophied inferior turbinate (HIT) who underwent partial inferior turbinectomy alone. | Procedure or surgery | Group III |
Primary outcome
Apnea-Hypopnea Index
Time frame: 3 months postoperatively
The Apnea-Hypopnea Index (AHI) is a critical metric used to diagnose and rank the severity of sleep apnea. It measures the average number of times your breathing completely stops (apneas) or becomes severely shallow (hypopneas) per hour of sleep.
1 secondary outcome
Snoring index
Time frame: 3 months postoperatively
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 3 Jun 2026.
- Individual participant dataSharing planned: Yes. The data will be available upon a reasonable request from the corresponding author after the end of study for one year.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Septoplasty with partial inferior turbinectomy, Nasal polypectomy and Partial inferior turbinectomy in people with Nasal Surgery and Snoring, run by Al-Azhar University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 3 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Apnea-Hypopnea Index (time frame: 3 months postoperatively). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 3 Jun 2026.