Clinical trials: Nasal Surgery
Dexmedetomidine, Bleeding
Dexmedetomidine Improves the Surgical Field and Postoperative Recovery of Nasal Endoscopic Surgery
Studies showed dexmedetomidine (DEX) could improve surgical field, but the effect for functional nasal endoscopic surgery (FESS) was unclear.
- Conditions
- Dexmedetomidine, Bleeding, Surgical Field
- Trial name
- NCT04276545
- Testing
- IV administration of DEX to investigate the effects for functional nasal endoscopic surgery, IV administration of Midazolam to investigate the effects for functional nasal endoscopic surgery
- Where
- China
- Volunteers
- 118 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Lung Neoplasms, Pneumothorax
HFNO Improves Blood Oxygen Saturation During Asphyxia During Pulmonary Surgery With Double-lumen Endotracheal Intubation
With the continuous strengthening of the concept of rapid rehabilitation, great progress has been made in minimally invasive thoracic surgery, and thoracoscopic surgery has developed rapidly.
- Trial name
- NCT05666908
- Testing
- HFNO
- Volunteers
- 112 people
- Sponsor
- Shenzhen Second People's Hospital
Complication of Surgical Procedure
Testing the Efficacy and Safety of the WEI Nasal Jet
Testing the efficacy and safety of the WEI Nasal Jet.
- Trial name
- WNJ (NCT02005406)
- Testing
- Experimental group and control groupl
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Zeyong Yang
Apneic Oxygenation, High-flow Nasal Cannulae
High-flow Nasal Oxygenation in Obese Patients During Apnea
Before going off to sleep patients are given oxygen to saturate blood with oxygen to extend time before a decrease in the level of oxygen in the blood occurs.
- Conditions
- Apneic Oxygenation, High-flow Nasal Cannulae, Bariatric Surgery, Anesthesia Induction
- Trial name
- NCT03195504
- Testing
- HFNC, CON (control)
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University Health Network, Toronto
Endotracheal Tube Wrongly Placed During Anesthetic Procedure
Modified Magill Forceps Facilitating Nasal Intubation for Children Undergoing Dental Operations
compare between Magill forceps and modified pediatric Magill forceps for nasotracheal intubation (which method is easier and better?).
- Trial name
- NCT05513989
- Testing
- modified Magill forceps, Magill forceps
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Ain Shams University
Nose Deformities, Acquired
Evaluation Of Cloumella Strut Effect In Tip Rotation
The role of strut in rhinoplasty has been debated for many years and many research has been made over this problem but there is no significant data for descision of surgeon, so this study was designed to evaluate the effect of…
- Trial name
- NCT00467714
- Testing
- rhinoplasty
- Where
- Iran
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Tehran University of Medical Sciences
Healthcare Associated Infection, Nosocomial Infection
Red Light Photobiomodulation and Topical Disinfectants
The goal of this clinical trial is to evaluate the potential effects of photobiomodulation when used with topical disinfectants in the anterior nares of healthy adults.
- Conditions
- Healthcare Associated Infection, Nosocomial Infection, Surgical Site Infection
- Trial name
- NCT05797818
- Testing
- Methylene Blue Only, Chlorhexidine Gluconate Only, Methylene Blue + Chlorhexidine Gluconate
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Ondine Biomedical Inc.
Paranasal Sinus Cancer, Nasal Cavity Tumor
A Clinical Trial of Endoscopic Surgery Followed by Chemotherapy and Proton Radiation for the Treatment of Tumors in the Sinus and Nasal Passages
This study is being done to test a new treatment plan for large tumors in the sinus or nasal cavity that will include endoscopic surgery plus chemotherapy and proton-beam radiation therapy.
- Conditions
- Paranasal Sinus Cancer, Nasal Cavity Tumor, Nasal Cavity Adenocarcinoma
- Trial name
- NCT03274414
- Testing
- Cisplatin, Adjuvant Proton Radiotherapy, Endoscopic Resection
- Where
- 5 sites in United States
- Volunteers
- 3 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Colorectal Cancer
Comparison of NOSES and Conventional Laparoscopic Surgery in Colorectal Cancer
Radical surgery for rectal cancer has evolved from the initial concept of total mesorctal excision (TME) to the wide application of laparoscopic surgery in the radical treatment of rectal cancer.
- Trial name
- NCT04559087
- Testing
- Laparoscopic Surgery
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Zunyi Medical College
Surgical Incision
Comparison of NOSE and Conventional Methods in Laparoscopic Total Colon Surgery
Laparoscopic total colectomy (LTC) is an accepted surgical procedure for several colonic pathologies. Additionally, specimen extraction through the natural orifices is an emerging method when combined with the totally…
- Trial name
- NCT03499769
- Testing
- natural orifice
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Inonu University
Thoracic Surgery
High-Flow Nasal Catheter (HFNC) Compared With Conventional Oxygenation
The purpose of this study, is to clarify whether there is benefit from the perioperative use of HFNC in thoracic surgeries, from intubation to the postoperative period, evaluating hipoxemia during orotracheal intubation…
- Trial name
- NCT05910788
- Testing
- high flow nasal cannula
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Agitation
Emergence Agitation After Nasal Surgery: a Randomized Controlled Comparison Between Melatonin and Mirtazapine
Emergence agitation (EA) is common after nasal surgery under general anesthesia, which can lead to several problems, such as increased risk of injury to the patient or medical staff, pain, decreased patient satisfaction…
- Trial name
- NCT04908605
- Testing
- Mirtazapine, Melatonin
- Where
- Egypt
- Volunteers
- 165 people
- Sponsor
- Ain Shams University
Nasal Polyps
Infrazygomatic Versus Intranasal Injection Sphinopalatine Ganglion Blockade Effect on Surgical Field in FESS
This study aimed to show the effect of sphinopalatine ganglion blockade on surgical field, hemodynamics and postoperative pain in FEES operation.
- Trial name
- NCT04996576
- Testing
- infrazygomatic approach sphinopalatine ganglion block, intranasal injection approach of sphinopalatine ganglion block
- Where
- 2 sites in Egypt
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Paranasal Sinus Diseases, Nasal Diseases
Design of an Augmented Reality System by Integration of CT Scan or MRI Data With Endoscopic Images for Video-assisted Endonasal Endoscopic Surgery
The gold standard surgical treatment for benign nasosinus pathologies is endoscopic surgery. This surgery has experienced considerable growth over the last 30 years.
- Conditions
- Paranasal Sinus Diseases, Nasal Diseases, Lacrimal Apparatus Diseases
- Trial name
- NORA (NCT04968561)
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Clermont-Ferrand
Sinusitis
Gold Laser Vs. Micro-Debriders for Functional Endoscopic Sinus Surgery
Sinusitis is a common medical problem, which significantly decreases patients' quality of life (QOL). Patients may have symptoms such as headaches, sinus pressure, nasal congestion and drainage, decreased sense of smell, and…
- Trial name
- NCT02900794
- Testing
- Gold Laser, Microdebridement
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Facial Deformity, Implant Complication
Optimizing Surgical and Prosthetic Workflow for Implant-supported Ear and Nose Prostheses With Early Loading and Distant Prosthesis Fabrication: A Prospective Cohort Study
Facial defects created by trauma, oncological procedures or congenital conditions can be repaired with ear, nose and/or eye prostheses. These are fixed on intraosseous implants placed in the temporal, nasal and orbital bone.
- Trial name
- NCT06506695
- Testing
- Craniofacial implant placement
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Pulmonary Atelectasis, Postoperative Complications
poStoperative Anesthesia Care: Facial Mask vs Hfnc and Thoracic Ultrasound for Reduction of Atelectasis Incidence
The primary aim of this study is to assess the efficacy of post-operatory HFNC in reducing the incidence of hypoxemia after gynecological oncology surgery, compared to the standard application of O2 through a Venturi mask; The…
- Conditions
- Pulmonary Atelectasis, Postoperative Complications, Gynecologic Cancer, Anesthesia
- Trial name
- SAMURAI (NCT04566419)
- Testing
- HFNC - Airvo 2, Oxygen
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Sinusitis
Rates of Middle Meatal Synechia Formation Following Functional Endoscopic Sinus Surgery
Functional endoscopic sinus surgery (FESS) is the best method of surgically treating patients who suffer from sinus disease. Synechiae formation in the nose is the most common complication after sinus surgery.
- Trial name
- SYNECHIAE (NCT02077322)
- Testing
- Silastic Spacer, Merocel Spacer
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- St. Paul's Hospital, Canada
Sinusitis
PerClot to Control Bleeding in Endoscopic Sinus Surgery
A prospective, single centre, single arm study designed to collect clinical data on PerClot when used in subjects undergoing endoscopic sinus surgery.
- Trial name
- NCT02221128
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- CryoLife Europa
Chronic Rhinosinusitis (Diagnosis), Surgery
A Study of Different Endoscopic Surgery Procedures in Eosinophilic Chronic Rhinosinusitis With Nasal Polyps
CRS remains a common challenging clinical entity due to variable phenotypes with different underlying mechanisms that lead to persistence or recurrence polyps.
- Trial name
- NCT03878355
- Testing
- radical endoscopic sinus surgery (RESS) plus Draf 3 surgery., radical endoscopic sinus surgery (RESS), functional endoscopic sinus surgery (FESS)
- Volunteers
- 27 people
- Sponsor
- Beijing Tongren Hospital