Nerve BlockRANCT07641842
Shoulder RA Survey Study
An observational study of Nerve Block, run by University Health Network, Toronto at 1 site in Canada.
Trial summary
The purpose of this study, called a cross-sectional survey, is to interview patients on their experiences of pain and recovery following keyhole shoulder surgery, after receiving a single shot nerve block in addition to a general anesthetic. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Nerve Block
- How many people
- 140 participants
- Where
- 1 siteCanada
- Study dates
- 5 Jun 2026to 31 Dec 2026
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Patients scheduled for for an arthroscopic shoulder surgery at Toronto Western Hospital and Women's College Hospital, Toronto.
Who may be able to join
- Participants must meet all the following inclusion criteria to be eligible for the study:
- Patients receiving a single-injection PNB for outpatient arthroscopic shoulder surgery at TWH and WCH
- Age ≥18 years
- Able to communicate in English
Who cannot join
- Cognitive impairment (inability to consent to participate in study)
- Refusal to participate in study
- Patients with primary block failure defined as those without a detectable sensory or motor block (determined by inability to abduct the arm and numbness or loss of sensation to pinprick over lateral shoulder/deltoid muscle, C5 dermatome)
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Ki Jinn Chin, MBBS MD FRCPC contact
Canada1 site, 1 recruiting
- Recruiting
Toronto Western Hospital, University Health Network
Toronto, Ontario, M5T 2S8
Jayanta Chowdhury, 4166035800 ext. 2016, jayanta.chowdhury@uhn.ca
Ki Jinn Chin, MBBS, MD, FRCPC
About this study
Official title: Patient Experience of Benefits and Limitations of Single Injection Peripheral Nerve Block for Shoulder Surgery: A Cross-sectional Survey
The purpose of this study, called a cross-sectional survey, is to interview patients on their experiences of pain and recovery following keyhole shoulder surgery, after receiving a single shot nerve block in addition to a general anesthetic. The researchers would like to explore patients' experiences to see if there are groups of patients who may benefit from insertion of a nerve catheter as compared to a single shot nerve block injection for keyhole shoulder surgery.
Read the detailed description
At Toronto Western Hospital (TWH) and Women's College Hospital (WCH), Toronto, the standard anesthetic given to patients undergoing keyhole shoulder surgery is a single shot nerve block, followed by a general anesthetic. Shoulder surgery is known to be painful, and the main aim of the nerve block is to provide pain relief once you wake up after surgery. A nerve block involves using an ultrasound machine to help inject local anesthetic medicine around the nerves which supply the shoulder, and a single shot injection lasts for 12-24 hours after the operation.
Patients may experience 'rebound' pain once the nerve block wears off, which may be severe. There is evidence suggesting that prolonging the duration of pain relief offered by the nerve block by insertion of a nerve catheter may be helpful in reducing 'rebound' pain. A nerve catheter is a thin tube which delivers local anesthetic pain relief continuously around the nerve, it can prolong the duration of pain relief from 12-24 hours to 48-72 hours.
The purpose of this study, is to interview patients on their experiences of pain and recovery following keyhole shoulder surgery, after receiving a single shot nerve block in addition to a general anesthetic. The researchers would like to explore patients' experiences to see if there are groups of patients who may benefit from insertion of a nerve catheter as compared to a single shot nerve block injection for keyhole shoulder surgery.
The followings will be done as part of the study:
Before Surgery:
After the patients consent to participate in this study, the study team will collect information from their medical records and by interviewing them, which includes age; height; weight; sex; ASA (American Society of Anesthesiologists) classification; frailty; history of previous nerve blocks; history of depression/anxiety; history of chronic pain; medicine history.
Day of Surgery:
The participants will receive standard clinical care for their surgery. The research team will collect information about their surgery from their medical chart.
After Surgery:
(While the participants are in the hospital)
The research team will provide the participants as part of their discharge paperwork, a set of written standardized instructions regarding their post-surgical pain control regimen.
(After the participants leave hospital)
The research team will collect information about their health from their medical chart and by interviewing them over the phone.
Telephone Follow-Up
Once the participants return home, they will be contacted by telephone to participate in two telephone interviews. The first one will take place 48-72 hours after their surgery, and the second one will take place a week after their surgery. During the interviews, they will speak with a member of the research team. Each interview will be about a maximum of 10 minutes in length and will take place while they are at home. They will be asked to provide information about their experiences with pain and the quality of recovery after their shoulder surgery. Based on their experience with the single-injection nerve block, investigators will also inquire whether they would have preferred a continuous nerve block catheter infusion.
- Conditions
- Nerve Block
- Keywords
- Nerve block, Nerve catheter block, Shoulder Arthroscopic Surgery, Survey, Continuous nerve block catheter infusion
What is being measured
The primary outcome is the main question the study is designed to answer.
To determine the proportion of patients who have a preference for nerve block with a continuous infusion versus a single injection of local anesthetic
To determine the proportion of patients undergoing outpatient arthroscopic shoulder surgery who have a preference for prolongation of their peripheral nerve block with a continuous infusion versus a single injection of local anesthetic
Measured: Through study completion, an average of 1 year
Secondary outcomes (6)
To determine predictive factors for catheter preference based on demographic characteristics
To determine predictive factors for catheter preference based on demographic characteristics
Measured: Through study completion, an average of 1 year
To determine predictive factors for catheter preference based on type and duration of shoulder surgery
To determine predictive factors for catheter preference based on type and duration of shoulder surgery
Measured: Through study completion, an average of 1 year
To determine predictive factors for catheter preference based on pre-operative anxiety defined by the PROMIS Anxiety Scale short form 8a
PROMIS Anxiety Scale measures self-reported anxiety traits based on 8 questions. Each question are rated on a 5-point scale (1-5) to get a total score between 5-40
Measured: Through study completion, an average of 1 year
To determine predictive factors for catheter preference based on pre-operative frailty
Frail scale evaluates five areas assigning 1 point for each if present and zero if absent. Total score 0-5. Robust=0; Pre-frail=1-2 and Frail=3-5
Measured: Through study completion, an average of 1 year
To identify the incidence of rebound pain following single-injection PNB (Peripheral Nerve Block)
To identify the incidence of rebound pain following single-injection PNB measured in percentage
Measured: Through study completion, an average of 1 year
To explore the association between experience of rebound pain and patient preference for a continuous nerve catheter
This association will be measured in only those participants that experienced rebound pain. This will be measured by calculating the number of patients that expressed a preference for continuous nerve catheter among those participants that experienced rebound pain and will be expressed as a percentage.
Measured: Through study completion, an average of 1 year
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted11 Jun 2026
- Study start5 Jun 2026
- Primary completion31 Dec 2026 (estimated)
- Study completion31 Dec 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Nerve BlockStudies of the same condition, open and under way.
- More trials run by University Health Network, TorontoThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 140 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University Health Network, Toronto
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Ki Jinn Chin, MBBS MD FRCPC, Principal investigator, University Health Network, Toronto
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07641842
- Sponsor's protocol ID
- 25-6110
- Other IDs
- CTO Project ID# 5621
- Acronym
- RA
- Status last verified
- Apr 2026
- First submitted
- 7 May 2026
- Last updated
- 31 Jul 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 31 Jul 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Patient Experience of Benefits and Limitations of Single Injection Peripheral Nerve Block for Shoulder Surgery: A Cross-sectional Survey
- ClinicalTrials.gov ID
- NCT07641842
- Acronym / sponsor ID
- RA / 25-6110
- Conditions
- Nerve Block
- Keywords
- Nerve block, Nerve catheter block, Shoulder Arthroscopic Surgery, Survey, Continuous nerve block catheter infusion
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 140 participants (estimated)
- Lead sponsor
- University Health Network, TorontoUniversity, hospital or other
- Study start
- 5 Jun 2026 (actual)
- Primary completion
- 31 Dec 2026 (estimated)
- Study completion
- 31 Dec 2026 (estimated)
- First posted
- 11 Jun 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of this study, called a cross-sectional survey, is to interview patients on their experiences of pain and recovery following keyhole shoulder surgery, after receiving a single shot nerve block in addition to a general anesthetic. The researchers would like to explore patients' experiences to see if there are groups of patients who may benefit from insertion of a nerve catheter as compared to a single shot nerve block injection for keyhole shoulder surgery.
Detailed description
At Toronto Western Hospital (TWH) and Women's College Hospital (WCH), Toronto, the standard anesthetic given to patients undergoing keyhole shoulder surgery is a single shot nerve block, followed by a general anesthetic. Shoulder surgery is known to be painful, and the main aim of the nerve block is to provide pain relief once you wake up after surgery. A nerve block involves using an ultrasound machine to help inject local anesthetic medicine around the nerves which supply the shoulder, and a single shot injection lasts for 12-24 hours after the operation.
Patients may experience 'rebound' pain once the nerve block wears off, which may be severe. There is evidence suggesting that prolonging the duration of pain relief offered by the nerve block by insertion of a nerve catheter may be helpful in reducing 'rebound' pain. A nerve catheter is a thin tube which delivers local anesthetic pain relief continuously around the nerve, it can prolong the duration of pain relief from 12-24 hours to 48-72 hours.
The purpose of this study, is to interview patients on their experiences of pain and recovery following keyhole shoulder surgery, after receiving a single shot nerve block in addition to a general anesthetic. The researchers would like to explore patients' experiences to see if there are groups of patients who may benefit from insertion of a nerve catheter as compared to a single shot nerve block injection for keyhole shoulder surgery.
The followings will be done as part of the study:
Before Surgery:
After the patients consent to participate in this study, the study team will collect information from their medical records and by interviewing them, which includes age; height; weight; sex; ASA (American Society of Anesthesiologists) classification; frailty; history of previous nerve blocks; history of depression/anxiety; history of chronic pain; medicine history.
Day of Surgery:
The participants will receive standard clinical care for their surgery. The research team will collect information about their surgery from their medical chart.
After Surgery:
(While the participants are in the hospital)
The research team will provide the participants as part of their discharge paperwork, a set of written standardized instructions regarding their post-surgical pain control regimen.
(After the participants leave hospital)
The research team will collect information about their health from their medical chart and by interviewing them over the phone.
Telephone Follow-Up
Once the participants return home, they will be contacted by telephone to participate in two telephone interviews. The first one will take place 48-72 hours after their surgery, and the second one will take place a week after their surgery. During the interviews, they will speak with a member of the research team. Each interview will be about a maximum of 10 minutes in length and will take place while they are at home. They will be asked to provide information about their experiences with pain and the quality of recovery after their shoulder surgery. Based on their experience with the single-injection nerve block, investigators will also inquire whether they would have preferred a continuous nerve block catheter infusion.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Patients scheduled for for an arthroscopic shoulder surgery at Toronto Western Hospital and Women's College Hospital, Toronto.
Key inclusion criteria (4 listed)
- Patients receiving a single-injection PNB for outpatient arthroscopic shoulder surgery at TWH and WCH
- Age ≥18 years
- Able to communicate in English
Key exclusion criteria (3 listed)
- Cognitive impairment (inability to consent to participate in study)
- Refusal to participate in study
- Patients with primary block failure defined as those without a detectable sensory or motor block (determined by inability to abduct the arm and numbness or loss of sensation to pinprick over lateral shoulder/deltoid muscle, C5 dermatome)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
To determine the proportion of patients who have a preference for nerve block with a continuous infusion versus a single injection of local anesthetic
Time frame: Through study completion, an average of 1 year
To determine the proportion of patients undergoing outpatient arthroscopic shoulder surgery who have a preference for prolongation of their peripheral nerve block with a continuous infusion versus a single injection of local anesthetic
6 secondary outcomes
To determine predictive factors for catheter preference based on demographic characteristics
Time frame: Through study completion, an average of 1 year
To determine predictive factors for catheter preference based on type and duration of shoulder surgery
Time frame: Through study completion, an average of 1 year
To determine predictive factors for catheter preference based on pre-operative anxiety defined by the PROMIS Anxiety Scale short form 8a
Time frame: Through study completion, an average of 1 year
To determine predictive factors for catheter preference based on pre-operative frailty
Time frame: Through study completion, an average of 1 year
To identify the incidence of rebound pain following single-injection PNB (Peripheral Nerve Block)
Time frame: Through study completion, an average of 1 year
To explore the association between experience of rebound pain and patient preference for a continuous nerve catheter
Time frame: Through study completion, an average of 1 year
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 31 Jul 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Ki Jinn Chin, MBBS MD FRCPC contact
Ki Jinn Chin, MBBS MD FRCPC principal investigator
University Health Network, Toronto
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Nerve Block, run by University Health Network, Toronto at 1 site in Canada.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 31 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Canada. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Jayanta Chowdhury (4166035800 ext. 2016, jayanta.chowdhury@uhn.ca), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
To determine the proportion of patients who have a preference for nerve block with a continuous infusion versus a single injection of local anesthetic (time frame: Through study completion, an average of 1 year). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 31 Jul 2026.