Cervical RadiculopathyNDM-CRNCT07643701
Neurodynamic Mobilization for Cervical Radiculopathy
A study testing neurodynamic mobilization and conventional physiotherapy in people with Cervical Radiculopathy, run by Lebanese German University at 1 site in Lebanon.
Trial summary
Cervical radiculopathy is a condition caused by compression or irritation of cervical nerve roots, leading to neck pain, arm pain, sensory disturbances, and functional limitations. Read more about this study
- Who is it for?
- Ages 18 to 65 years
- Conditions the study is for
- Cervical Radiculopathy
- What is being tested?
- neurodynamic mobilization and conventional physiotherapy
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 50 participants
- Where
- 1 siteLebanon
- Study dates
- 1 Nov 2024to 28 Feb 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Adults aged 18-65 years.
- Diagnosis of cervical radiculopathy.
- pain radiating to the upper limb.
- Presence of at least one neurological sign, including: Sensory deficit, or Muscle weakness, or Diminished reflexes.
Who cannot join
- Previous cervical spine surgery.
- Cervical myelopathy.
- Cervical fractures.
- Tumors affecting the cervical spine.
- Inflammatory disorders.
- Any contraindication to physiotherapy interventions.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Effectiveness of Adding Neurodynamic Mobilization to Conventional Physiotherapy in Patients With Cervical Radiculopathy: A Randomized Controlled Trial
Cervical radiculopathy is a condition caused by compression or irritation of cervical nerve roots, leading to neck pain, arm pain, sensory disturbances, and functional limitations. This randomized controlled trial evaluated whether adding neurodynamic mobilization to conventional physiotherapy improves pain intensity and functional disability in individuals with cervical radiculopathy. Participants received either conventional physiotherapy alone or conventional physiotherapy combined with neurodynamic mobilization over a 5-week treatment period.
Read the detailed description
Cervical radiculopathy is a condition where a nerve in the neck becomes irritated or compressed. This can cause neck pain, pain that spreads into the arm, numbness, tingling, and difficulty performing daily activities. It can significantly affect a person's quality of life.
This study investigated whether adding a specific physiotherapy technique called neurodynamic mobilization to standard physiotherapy could improve recovery in patients with cervical radiculopathy.
A total of 50 participants took part in the study. They were randomly divided into two groups. One group received standard physiotherapy treatment only, while the other group received standard physiotherapy combined with neurodynamic mobilization techniques.
Both treatment programs were carried out over five weeks, with a total of 10 treatment sessions.
Participants were evaluated before and after treatment to measure pain levels and how much their neck condition affected daily activities. Pain was measured using a simple rating scale, and disability was measured using a questionnaire.
The results showed that both groups improved over time. However, the group that received the additional neurodynamic mobilization experienced greater reductions in pain and better improvement in daily function compared to the group that received standard physiotherapy alone.
The study suggests that adding neurodynamic mobilization may enhance the effectiveness of physiotherapy for people with cervical radiculopathy.
- Conditions
- Cervical Radiculopathy
- Being tested
- neurodynamic mobilization, conventional physiotherapy
- Medical subject headings
- Radiculopathy
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
neurodynamic mobilizationOther
Neurodynamic mobilization consisted of specific neural tissue mobilization techniques targeting the affected cervical nerve roots. The techniques were applied in addition to conventional physiotherapy and aimed to restore normal neural mobility and reduce mechanosensitivity. Treatment was delivered over 5 weeks (10 sessions). Each session included standardized neurodynamic sliding techniques performed within pain-free or low-pain ranges, combined with conventional physiotherapy interventions including therapeutic exercises, manual therapy, and physical modalities. The intervention was individually tailored based on patient symptoms and clinical presentation.
conventional physiotherapyOther
Conventional physiotherapy consisted of a standardized rehabilitation program including therapeutic exercises, manual therapy techniques, and physical modalities. Therapeutic exercises focused on cervical range of motion, strengthening, and postural correction. Manual therapy included soft tissue techniques and joint mobilization of the cervical spine. Physical modalities were applied to reduce pain and improve function. The intervention was delivered over 5 weeks, with a total of 10 sessions.
| Study group | Role | What they receive |
|---|---|---|
| Conventional Physiotherapy | Experimental | Participants received conventional physiotherapy including therapeutic exercises, manual therapy, and physical modalities aimed at reducing pain and improving function. Receives: Other: conventional physiotherapy |
| Conventional Physiotherapy + Neurodynamic Mobilization | Experimental | Participants received conventional physiotherapy including therapeutic exercises, manual therapy, and physical modalities aimed at reducing pain and improving function. In addition, neurodynamic mobilization techniques targeting cervical nerve roots were applied to improve neural mobility and reduce mechanosensitivity. The intervention was delivered over 5 weeks, with a total of 10 sessions. Techniques included neurodynamic sliding mobilization performed within pain-free or low-pain ranges, individually adapted to patient symptoms. Receives: Other: neurodynamic mobilization; Other: conventional physiotherapy |
What is being measured
The primary outcome is the main question the study is designed to answer.
Pain Intensity
Pain intensity will be assessed using the Visual Analogue Scale (VAS), a validated self-reported measure of pain severity. The scale ranges from 0 to 10, where 0 indicates no pain and 10 indicates the worst imaginable pain. Higher scores indicate greater pain intensity.
Measured: Baseline and after 5 weeks of intervention.
Secondary outcomes (1)
Functional Disability
Functional disability will be assessed using the Neck Disability Index (NDI), a validated questionnaire designed to evaluate the impact of neck pain on daily activities. The NDI consists of 10 items, with total scores ranging from 0 to 50. Higher scores indicate greater neck-related disability.
Measured: Baseline and after 5 weeks of intervention.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted11 Jun 2026
- Study start1 Nov 2024
- Primary completion28 Feb 2025
- Study completion28 Feb 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Cervical RadiculopathyStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 50 participants (actual)
Sponsor and investigators
- Lead sponsor
- Lebanese German University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Marie-Louise Ayoub, Lebanese German University
- Investigators
- Samir Matar, Professor, Study chair, Lebanese German University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07643701
- Sponsor's protocol ID
- LGU-DPT-RCT-2024-01
- Other IDs
- pk4fs
- Acronym
- NDM-CR
- Status last verified
- Jun 2026
- First submitted
- 26 May 2026
- Last updated
- 12 Jun 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Individual participant data will not be shared due to privacy and confidentiality considerations.
Study at a glance
From the registry record, last updated by the sponsor on 12 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effectiveness of Adding Neurodynamic Mobilization to Conventional Physiotherapy in Patients With Cervical Radiculopathy: A Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT07643701
- Acronym / sponsor ID
- NDM-CR / LGU-DPT-RCT-2024-01
- Conditions
- Cervical Radiculopathy
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 50 participants (actual)
- Lead sponsor
- Lebanese German UniversityUniversity, hospital or other
- Study start
- 1 Nov 2024 (actual)
- Primary completion
- 28 Feb 2025 (actual)
- Study completion
- 28 Feb 2025 (actual)
- First posted
- 11 Jun 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Cervical radiculopathy is a condition caused by compression or irritation of cervical nerve roots, leading to neck pain, arm pain, sensory disturbances, and functional limitations. This randomized controlled trial evaluated whether adding neurodynamic mobilization to conventional physiotherapy improves pain intensity and functional disability in individuals with cervical radiculopathy. Participants received either conventional physiotherapy alone or conventional physiotherapy combined with neurodynamic mobilization over a 5-week treatment period.
Detailed description
Cervical radiculopathy is a condition where a nerve in the neck becomes irritated or compressed. This can cause neck pain, pain that spreads into the arm, numbness, tingling, and difficulty performing daily activities. It can significantly affect a person's quality of life.
This study investigated whether adding a specific physiotherapy technique called neurodynamic mobilization to standard physiotherapy could improve recovery in patients with cervical radiculopathy.
A total of 50 participants took part in the study. They were randomly divided into two groups. One group received standard physiotherapy treatment only, while the other group received standard physiotherapy combined with neurodynamic mobilization techniques.
Both treatment programs were carried out over five weeks, with a total of 10 treatment sessions.
Participants were evaluated before and after treatment to measure pain levels and how much their neck condition affected daily activities. Pain was measured using a simple rating scale, and disability was measured using a questionnaire.
The results showed that both groups improved over time. However, the group that received the additional neurodynamic mobilization experienced greater reductions in pain and better improvement in daily function compared to the group that received standard physiotherapy alone.
The study suggests that adding neurodynamic mobilization may enhance the effectiveness of physiotherapy for people with cervical radiculopathy.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Conventional Physiotherapy | Experimental | Other: conventional physiotherapyParticipants received conventional physiotherapy including therapeutic exercises, manual therapy, and physical modalities aimed at reducing pain and improving function. |
| Conventional Physiotherapy + Neurodynamic Mobilization | Experimental | Other: neurodynamic mobilization, Other: conventional physiotherapyParticipants received conventional physiotherapy including therapeutic exercises, manual therapy, and physical modalities aimed at reducing pain and improving function. In addition, neurodynamic mobilization techniques targeting cervical nerve roots were applied to improve neural mobility and reduce mechanosensitivity. The intervention was delivered over 5 weeks, with a total of 10 sessions. Techniques included neurodynamic sliding mobilization performed within pain-free or low-pain ranges, individually adapted to patient symptoms. |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- Adults aged 18-65 years.
- Diagnosis of cervical radiculopathy.
- pain radiating to the upper limb.
- Presence of at least one neurological sign, including: Sensory deficit, or Muscle weakness, or Diminished reflexes.
Key exclusion criteria (6 listed)
- Previous cervical spine surgery.
- Cervical myelopathy.
- Cervical fractures.
- Tumors affecting the cervical spine.
- Inflammatory disorders.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| neurodynamic mobilizationNeurodynamic mobilization consisted of specific neural tissue mobilization techniques targeting the affected cervical nerve roots. The techniques were applied in addition to conventional physiotherapy and aimed to restore normal neural mobility and reduce mechanosensitivity. Treatment was delivered over 5 weeks (10 sessions). Each session included standardized neurodynamic sliding techniques performed within pain-free or low-pain ranges, combined with conventional physiotherapy interventions including therapeutic exercises, manual therapy, and physical modalities. The intervention was individually tailored based on patient symptoms and clinical presentation. | Other | Conventional Physiotherapy + Neurodynamic Mobilization |
| conventional physiotherapyConventional physiotherapy consisted of a standardized rehabilitation program including therapeutic exercises, manual therapy techniques, and physical modalities. Therapeutic exercises focused on cervical range of motion, strengthening, and postural correction. Manual therapy included soft tissue techniques and joint mobilization of the cervical spine. Physical modalities were applied to reduce pain and improve function. The intervention was delivered over 5 weeks, with a total of 10 sessions. | Other | Conventional Physiotherapy, Conventional Physiotherapy + Neurodynamic Mobilization |
Primary outcome
Pain Intensity
Time frame: Baseline and after 5 weeks of intervention.
Pain intensity will be assessed using the Visual Analogue Scale (VAS), a validated self-reported measure of pain severity. The scale ranges from 0 to 10, where 0 indicates no pain and 10 indicates the worst imaginable pain. Higher scores indicate greater pain intensity.
1 secondary outcome
Functional Disability
Time frame: Baseline and after 5 weeks of intervention.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 12 Jun 2026.
- Individual participant dataSharing planned: No. Individual participant data will not be shared due to privacy and confidentiality considerations.
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Enrolling by invitation
Assessing Microbiome in Primary Anterior Cervical Fusion Patients
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Samir Matar, Professor study chair
Lebanese German University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing neurodynamic mobilization and conventional physiotherapy in people with Cervical Radiculopathy, run by Lebanese German University at 1 site in Lebanon.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 12 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Lebanon. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Pain Intensity (time frame: Baseline and after 5 weeks of intervention.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 12 Jun 2026.