AthletesSLDNCT07648537
The Effect of Muscular Fatigue on Lower Limb Kinematics During Single-Leg Drop Landing in Female Athletes
A study testing fatigue protocol in people with Athletes, run by Cairo University.
Trial summary
this study will be conducted to investigate the effect of muscular fatigue on lower limb kinematics during single-leg drop landing in female professional volleyball players using a mobile-based motion analysis application. Read more about this study
- Who is it for?
- Ages 20 to 25 years, women onlyHealthy volunteers can take part
- Conditions the study is for
- Athletes
- What is being tested?
- fatigue protocol
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 35 participants
- Where
- No sites listed yet
- Study dates
- 30 Jun 2026to 20 Dec 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 to 25 years
- Women only
- Healthy volunteers accepted
- Adult
Who may be able to join
- Female volleyball players aged 20-25 years
- Practice professional volleyball training or competition experience of at least 2 years
- typically engage in a high volume of training, with regular participation in at least five training sessions per week
- Willingness to adhere to fatigue protocol and provide informed consent
Who cannot join
- Current or recent (within the past 6 months) lower limb injury or medical condition
- History of lower limb surgeries
- Neurological disorders or balance impairments .
- Experiencing pain or discomfort during jumping or landing tasks
- Body mass index (BMI) greater than 30 kg/m²
- Inability to comply with the fatigue protocol or follow instructions for the landing tasks
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
About this study
this study will be conducted to investigate the effect of muscular fatigue on lower limb kinematics during single-leg drop landing in female professional volleyball players using a mobile-based motion analysis application.
Read the detailed description
Muscular fatigue impairs neuromuscular control and alters lower limb kinematics during dynamic tasks such as landing, increasing the risk of injury. For example, repetitive jump-landing tasks, as frequently performed in volleyball, have been shown to induce progressive changes in lower limb biomechanics, including reduced ankle plantarflexion and altered knee alignment, which may compromise energy absorption and joint stability.Female athletes face a higher incidence of knee and ligament injuries than males, including ACL tears and ankle sprains, due to sex-specific biomechanical and neuromuscular characteristics such as reduced hamstring activation, increased joint laxity, and altered landing mechanics .Markerless, smartphone-based systems such as OpenCap provide a validated, cost-effective, and field-based solution for 3D kinematic analysis.By applying OpenCap to evaluate the effects of muscular fatigue on single-leg drop landing in professional female volleyball players, this study aims to detect early deviations in movement patterns that may predispose athletes to injury. These findings can inform preseason screening and guide the development of tailored neuromuscular training programs, contributing to context-specific, sex-informed injury prevention strategies in female sport
- Conditions
- Athletes
- Being tested
- fatigue protocol
- Keywords
- Muscular Fatigue, Lower Limb Kinematics, Single-Leg Drop Landing, Female Athletes
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
fatigue protocolOther
Before formal testing, participants will perform a five-minute warm-up replicating their usual pre-volleyball training routine. Following the warm-up, the single-leg drop landing (SLDL) task will be clearly explained and demonstrated to all participants.Stand barefoot on both legs on a 30 cm box, then extend the testing leg forward. They will then step off the box using the testing leg, land on the same leg with a toe-heel landing pattern. After familiarization, participants will perform three trials of the SLDL task under non-fatigued conditions.Following the completion of the non-fatigue single-leg drop landing (SLDL) trials, each participant will perform three maximal vertical jumps to assess their maximum touch height. The highest value obtained from these attempts will be recorded as the participant's baseline for subsequent comparisons.Following the completion of the baseline maximal vertical jump assessment, participants will undergo a systematic fatigue induction protocol
| Study group | Role | What they receive |
|---|---|---|
| fatigue protocol | Experimental | Thirty five female professional volleyball players and aged between 18-25 years will be recruited from local Egyptian club. all femalles applief fatigue protocol Receives: Other: fatigue protocol |
What is being measured
The primary outcome is the main question the study is designed to answer.
hip range of motion
OpenCap will be used to assess hip range of motion. the Video recordings will be analyzed using OpenCap, a validated markerless motion capture system that estimates 3D joint kinematics from synchronized smartphone cameras through an automated pipeline that applies advanced computer vision and machine learning algorithms to extract joint angles efficiently and with high validity
Measured: up to one day
knee flexion range of motion
OpenCap will be used to assess knee flexion range of motion. the Video recordings will be analyzed using OpenCap, a validated markerless motion capture system that estimates 3D joint kinematics from synchronized smartphone cameras through an automated pipeline that applies advanced computer vision and machine learning algorithms to extract joint angles efficiently and with high validity
Measured: up to one day
ankle dorsiflexion range of motion
OpenCap will be used to assess ankle dorsiflexion range of motion. the Video recordings will be analyzed using OpenCap, a validated markerless motion capture system that estimates 3D joint kinematics from synchronized smartphone cameras through an automated pipeline that applies advanced computer vision and machine learning algorithms to extract joint angles efficiently and with high validity
Measured: up to one day
knee valgus angle
OpenCap will be used to assess knee valgus angle. the Video recordings will be analyzed using OpenCap, a validated markerless motion capture system that estimates 3D joint kinematics from synchronized smartphone cameras through an automated pipeline that applies advanced computer vision and machine learning algorithms to extract joint angles efficiently and with high validity
Measured: up to one day
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted15 Jun 2026
- Study start30 Jun 2026 (estimated)
- Primary completion20 Dec 2026 (estimated)
- Study completion20 Dec 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for AthletesStudies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Diagnosis
- Allocation
- Not applicable
- Intervention model
- Single group
- Model description
- fatigue protocol
- Masking
- None (open label)
- Enrolment
- 35 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Mawada Mohamed Meshref Ibrahim, Cairo University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07648537
- Sponsor's protocol ID
- P.T.REC/012/0067282
- Acronym
- SLD
- Status last verified
- Jun 2026
- First submitted
- 10 Jun 2026
- Last updated
- 15 Jun 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 15 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effect of Muscular Fatigue on Lower Limb Kinematics During Single-Leg Drop Landing in Female Athletes
- ClinicalTrials.gov ID
- NCT07648537
- Acronym / sponsor ID
- SLD / P.T.REC/012/0067282
- Conditions
- Athletes
- Keywords
- Muscular Fatigue, Lower Limb Kinematics, Single-Leg Drop Landing, Female Athletes
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 35 participants (estimated)
- Lead sponsor
- Cairo UniversityUniversity, hospital or other
- Study start
- 30 Jun 2026 (estimated)
- Primary completion
- 20 Dec 2026 (estimated)
- Study completion
- 20 Dec 2026 (estimated)
- First posted
- 15 Jun 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
this study will be conducted to investigate the effect of muscular fatigue on lower limb kinematics during single-leg drop landing in female professional volleyball players using a mobile-based motion analysis application.
Detailed description
Muscular fatigue impairs neuromuscular control and alters lower limb kinematics during dynamic tasks such as landing, increasing the risk of injury. For example, repetitive jump-landing tasks, as frequently performed in volleyball, have been shown to induce progressive changes in lower limb biomechanics, including reduced ankle plantarflexion and altered knee alignment, which may compromise energy absorption and joint stability.Female athletes face a higher incidence of knee and ligament injuries than males, including ACL tears and ankle sprains, due to sex-specific biomechanical and neuromuscular characteristics such as reduced hamstring activation, increased joint laxity, and altered landing mechanics .Markerless, smartphone-based systems such as OpenCap provide a validated, cost-effective, and field-based solution for 3D kinematic analysis.By applying OpenCap to evaluate the effects of muscular fatigue on single-leg drop landing in professional female volleyball players, this study aims to detect early deviations in movement patterns that may predispose athletes to injury. These findings can inform preseason screening and guide the development of tailored neuromuscular training programs, contributing to context-specific, sex-informed injury prevention strategies in female sport
Study design
- Primary purpose
- Diagnosis
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
- Model description
- fatigue protocol
| Arm | Type | Receives |
|---|---|---|
| fatigue protocol | Experimental | Other: fatigue protocolThirty five female professional volleyball players and aged between 18-25 years will be recruited from local Egyptian club. all femalles applief fatigue protocol |
Who may qualify
- Ages
- 20 to 25 years
- Sex
- Female only
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (4 listed)
- Female volleyball players aged 20-25 years
- Practice professional volleyball training or competition experience of at least 2 years
- typically engage in a high volume of training, with regular participation in at least five training sessions per week
- Willingness to adhere to fatigue protocol and provide informed consent
Key exclusion criteria (6 listed)
- Current or recent (within the past 6 months) lower limb injury or medical condition
- History of lower limb surgeries
- Neurological disorders or balance impairments .
- Experiencing pain or discomfort during jumping or landing tasks
- Body mass index (BMI) greater than 30 kg/m²
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| fatigue protocolBefore formal testing, participants will perform a five-minute warm-up replicating their usual pre-volleyball training routine. Following the warm-up, the single-leg drop landing (SLDL) task will be clearly explained and demonstrated to all participants.Stand barefoot on both legs on a 30 cm box, then extend the testing leg forward. They will then step off the box using the testing leg, land on the same leg with a toe-heel landing pattern. After familiarization, participants will perform three trials of the SLDL task under non-fatigued conditions.Following the completion of the non-fatigue single-leg drop landing (SLDL) trials, each participant will perform three maximal vertical jumps to assess their maximum touch height. The highest value obtained from these attempts will be recorded as the participant's baseline for subsequent comparisons.Following the completion of the baseline maximal vertical jump assessment, participants will undergo a systematic fatigue induction protocol | Other | fatigue protocol |
Primary outcome
hip range of motion
Time frame: up to one day
OpenCap will be used to assess hip range of motion. the Video recordings will be analyzed using OpenCap, a validated markerless motion capture system that estimates 3D joint kinematics from synchronized smartphone cameras through an automated pipeline that applies advanced computer vision and machine learning algorithms to extract joint angles efficiently and with high validity
knee flexion range of motion
Time frame: up to one day
OpenCap will be used to assess knee flexion range of motion. the Video recordings will be analyzed using OpenCap, a validated markerless motion capture system that estimates 3D joint kinematics from synchronized smartphone cameras through an automated pipeline that applies advanced computer vision and machine learning algorithms to extract joint angles efficiently and with high validity
ankle dorsiflexion range of motion
Time frame: up to one day
OpenCap will be used to assess ankle dorsiflexion range of motion. the Video recordings will be analyzed using OpenCap, a validated markerless motion capture system that estimates 3D joint kinematics from synchronized smartphone cameras through an automated pipeline that applies advanced computer vision and machine learning algorithms to extract joint angles efficiently and with high validity
knee valgus angle
Time frame: up to one day
OpenCap will be used to assess knee valgus angle. the Video recordings will be analyzed using OpenCap, a validated markerless motion capture system that estimates 3D joint kinematics from synchronized smartphone cameras through an automated pipeline that applies advanced computer vision and machine learning algorithms to extract joint angles efficiently and with high validity
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 15 Jun 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Questions about this trial
What is this clinical trial studying?
A study testing fatigue protocol in people with Athletes, run by Cairo University.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 15 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact mawada mohamed, master (+20 10 24330410, mawada.mooda96@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
hip range of motion (time frame: up to one day). The study lists 4 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 15 Jun 2026.