Bone LossAcetalResinNCT07666763
Influence of Acetal Resin Versus Nylon Elastic Cap on Crestal Bone Loss in Mandibular Implant-Supported Overdenture
A study testing Acetal Resin and nylon in people with Bone Loss and Pocket, Periodontal, run by Future University in Egypt.
Trial summary
Objective: To evaluate and compare the effect of two different attachment housing materials-Acetal Resin (Polyoxymethylene) versus conventional Nylon elastic caps-on marginal crestal bone loss around dental implants supporting a mandibular overdenture. Read more about this study
- Who is it for?
- Ages 40 to 60 years, men onlyHealthy volunteers can take part
- Conditions the study is for
- Bone Loss, Pocket, Periodontal
- What is being tested?
- Acetal Resin and nylon
- Type of treatment
- Medical device
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 22 participants
- Where
- No sites listed yet
- Study dates
- 1 Jul 2026to 1 Aug 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 40 to 60 years
- Men only
- Healthy volunteers accepted
- Adult
Who may be able to join
- Completely edentulous mandible.
- Sufficient bone height/width in mandibular residual ridges.
- Angles classification class I.
- Sufficient inter-arch distance
Who cannot join
- TMJ disorders.
- Diabetic
- Hypertensive
- Cancer patients.
- Smoker
- Osteoporosis.
- Immunosuppressive disease
- Any disease affecting bone/implant stability.
About this study
Objective: To evaluate and compare the effect of two different attachment housing materials-Acetal Resin (Polyoxymethylene) versus conventional Nylon elastic caps-on marginal crestal bone loss around dental implants supporting a mandibular overdenture. It also evaluates peri-implant clinical tissue health by measuring pocket depth and the gingival bleeding index.
Read the detailed description
Study Design \& Timeline: A prospective, double-blind, randomized controlled clinical trial with a 1:1 allocation ratio. Clinical and radiographic outcomes will be evaluated at overdenture insertion (baseline), and at 6 and 12 months post-insertion.ethodology \& Analysis: Pre-operative bone volume will be assessed via Cone Beam CT (CBCT). Crestal bone loss will be measured using the long cone parallel radiographic technique , while pocket depth and gingival bleeding will be measured using a William's graduated probing device. Data will undergo normality testing to determine the use of parametric (Independent t-test, Repeated Measures ANOVA) or non-parametric (Mann-Whitney, Friedman) statistical analyse
- Conditions
- Bone Loss, Pocket, Periodontal
- Being tested
- Acetal Resin, nylon
- Medical subject headings
- Bone Diseases, Metabolic, Periodontal Pocket
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Acetal ResinDevice
overdenture supported by implants
nylonDevice
overdenture supported by implants
| Study group | Role | What they receive |
|---|---|---|
| intervention | Experimental | acetal Receives: Device: Acetal Resin |
| control | Active comparator | Nylon Elastic Receives: Device: nylon |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in crestal bone levels
mm
Measured: one year
Secondary outcomes (1)
pocket depth changes
mm
Measured: one year
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted24 Jun 2026
- Study start1 Jul 2026 (estimated)
- Primary completion1 Jun 2027 (estimated)
- Study completion1 Aug 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Bone LossStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Triple blind
- Who is masked
- Participant, Care provider, Outcomes assessor
- Enrolment
- 22 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Future University in Egypt
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Seif eldin Diaa Ezzat, Future University in Egypt
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07666763
- Sponsor's protocol ID
- FUE
- Acronym
- AcetalResin
- Status last verified
- Jun 2026
- First submitted
- 7 Jun 2026
- Last updated
- 24 Jun 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: 1\. Chronological Timeline and FrameworkTrial Duration: The active comparative clinical trial is designed to span a duration of one year. Measurement Intervals: Data collection and patient evaluation are scheduled at three distinct time points: at overdenture insertion (baseline), at 6 months, and at 12 months post-insertion
Study at a glance
From the registry record, last updated by the sponsor on 24 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Influence of Acetal Resin Versus Nylon Elastic Cap on Crestal Bone Loss in Mandibular Implant-Supported Overdenture
- ClinicalTrials.gov ID
- NCT07666763
- Acronym / sponsor ID
- AcetalResin / FUE
- Conditions
- Bone Loss, Pocket, Periodontal
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 22 participants (estimated)
- Lead sponsor
- Future University in EgyptUniversity, hospital or other
- Study start
- 1 Jul 2026 (estimated)
- Primary completion
- 1 Jun 2027 (estimated)
- Study completion
- 1 Aug 2027 (estimated)
- First posted
- 24 Jun 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Objective: To evaluate and compare the effect of two different attachment housing materials-Acetal Resin (Polyoxymethylene) versus conventional Nylon elastic caps-on marginal crestal bone loss around dental implants supporting a mandibular overdenture. It also evaluates peri-implant clinical tissue health by measuring pocket depth and the gingival bleeding index.
Detailed description
Study Design \& Timeline: A prospective, double-blind, randomized controlled clinical trial with a 1:1 allocation ratio. Clinical and radiographic outcomes will be evaluated at overdenture insertion (baseline), and at 6 and 12 months post-insertion.ethodology \& Analysis: Pre-operative bone volume will be assessed via Cone Beam CT (CBCT). Crestal bone loss will be measured using the long cone parallel radiographic technique , while pocket depth and gingival bleeding will be measured using a William's graduated probing device. Data will undergo normality testing to determine the use of parametric (Independent t-test, Repeated Measures ANOVA) or non-parametric (Mann-Whitney, Friedman) statistical analyse
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Triple blind (participant, care provider, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| intervention | Experimental | Device: Acetal Resinacetal |
| control | Active comparator | Device: nylonNylon Elastic |
Who may qualify
- Ages
- 40 to 60 years
- Sex
- Male only
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (4 listed)
- Completely edentulous mandible.
- Sufficient bone height/width in mandibular residual ridges.
- Angles classification class I.
- Sufficient inter-arch distance
Key exclusion criteria (8 listed)
- TMJ disorders.
- Diabetic
- Hypertensive
- Cancer patients.
- Smoker
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Acetal Resinoverdenture supported by implants | Device | intervention |
| nylonoverdenture supported by implants | Device | control |
Primary outcome
Change in crestal bone levels
Time frame: one year
mm
1 secondary outcome
pocket depth changes
Time frame: one year
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 24 Jun 2026.
- Individual participant dataSharing planned: No. 1. Chronological Timeline and FrameworkTrial Duration: The active comparative clinical trial is designed to span a duration of one year. Measurement Intervals: Data collection and patient evaluation are scheduled at three distinct time points: at overdenture insertion (baseline), at 6 months, and at 12 months post-insertion
Related trials for Bone Loss
Recruiting
Metabolic Health, Bones and Nuts During Weight Loss in Adults
Weight Loss, Bone Density
Not yet recruitingPhase 2
Melatonin in Posterior Mandible Extraction Socket
Bone Loss
Active, not recruitingObservational study
CFTR Modulator Effects on Bone and Muscle in Adults With Cystic Fibrosis
Cystic Fibrosis, Bone Loss
Active, not recruiting
AI-Supported Mobile High-Impact and Strengthening Exercise Program in Postmenopausal Women With Low Bone Density
Osteopenia
Active, not recruiting
L-PRF Block vs Composite Graft for Horizontal Ridge Augmentation
Alveolar Ridge Resorption After Extraction, Alveolar Bone Loss
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
The record lists no contact. Use the official record to reach the sponsor.
Questions about this trial
What is this clinical trial studying?
A study testing Acetal Resin and nylon in people with Bone Loss and Pocket, Periodontal, run by Future University in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 24 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in crestal bone levels (time frame: one year). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 24 Jun 2026.