Clinical trials: Pocket, Periodontal
Periodontal Bone Loss, Periodontal Pocket
Treatment of Intraosseous Periodontal Defects With Hyaluronic Acid
The aim of the present investigation will be evaluate the healing of periodontal intraosseous defects following Minimally Invasive Non Surgical Debridement (MINSD) and application of a hyaluronic acid-based gel, compared to MINSD…
- Trial name
- NCT05188898
- Testing
- MINSD and Hyaluronic acid, MINSD
- Where
- Italy
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Federico II University
Chronic Periodontitis
RELATIONSHIP BETWEEN INITIAL PROBING DEPTH AND CHANGES IN CLINICAL PARAMETERS FOLLOWING NON-SURGICAL PERIODONTAL TREATMENT IN CHRONIC PERIODONTITIS PATIENTS
Aim: The aim of this study was to evaluate the relationship between initial probing depth (IPD) and changes in clinical parameters following non-surgical periodontal treatment (NPT) in chronic periodontitis patients.
- Trial name
- NCT02861326
- Testing
- Gracey Curettes
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Marmara University
Periodontal Pocket
Glucosamine Sulphate Versus Ginger in Non-Surgical Periodontal Therapy
Glucosamine (GlcN) is an N-deacetyl amino monosaccharide sugar derived from complete hydrolysis of chitosan in which it is important vector for chondroitin and keratin sulfate, while on the other hand, medicinal plants became a…
- Trial name
- NCT06200415
- Testing
- Glucosamine Sulfate, Ginger Oil
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Periodontitis
Diode Laser 635 nm and 810 nm Photodynamic Therapy as Adjuncts to Non-Surgical Periodontal Treatment
This study aims to evaluate and compare the clinical effectiveness of antimicrobial photodynamic therapy (aPDT) using toluidine blue O (TBO) activated by two different diode laser wavelengths as an adjunct to non-surgical…
- Trial name
- NCT07849647
- Testing
- 635 nm Diode Laser-Mediated aPDT + Non-Surgical Periodontal Treatment, 810 nm Diode Laser-Mediated aPDT + Non-Surgical Periodontal Treatment, Non-Surgical Periodontal Treatment Alone (Control)
- Where
- Syria
- Volunteers
- 12 people
- Sponsor
- Damascus University
Periodontitis
Evaluation of Prognostic Potentials of Gingival Crevicular Fluid E-cadherin and Total Antioxidant Capacity
Ability to anticipate the outcomes of periodontal therapy at baseline visit is crucial to outline and customize a treatment plan with predictable outcomes and cost-effectiveness.
- Trial name
- NCT05994885
- Testing
- Root surface debridement
- Where
- Iraq
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ali A Abdulkareem
Pocket, Periodontal, Periodontal Inflammation
Diode Laser Photo Activation for Pocket Reduction Decontamination A Clinical Study
Routine non surgical periodontal thearpy often fails to achieve complete elimination of pathogenic microorganism. This could be attiributable to deep periodontal pockets, root concavities, furcation involvement etc.
- Conditions
- Pocket, Periodontal, Periodontal Inflammation, Periodontal Attachment Loss, Periodontitis
- Trial name
- NCT06404190
- Testing
- Diode laser and 3% hydrogen peroxide
- Where
- India
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Periodontal Diseases, Periodontal Inflammation
Minimally Non Surgical Periodontal Therapy Compared to Traditional Approach
This study aims to evaluate the clinical results of non-surgical periodontal therapy performed with micro-instruments compared to traditional approach (standard curettes) after 6 months of follow-up.
- Trial name
- NCT05060601
- Testing
- Gracey micro-curettes, Standard Gracey curettes
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Federico II University
Peri-Implantitis, Peri-implant Mucositis
Comparison of the Accuracy of Different Periodontal Probes for Peri-implant Pocket Registration
Various types of periodontal probes (e.g., metal probes, plastic/bendable probes, electronic periodontal probes) are used for peri-implant pocket depth registration; however, depending on the shape and size of the prosthetic…
- Trial name
- NCT05332327
- Where
- Sweden
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Malmö University
Periodontal Diseases, Periodontal Pocket
Effectiveness of SRP+ Lipo-curcumin Gel for the Treatment of Stage III Periodontitis.
The aim of the present study is to clinically and radiographically compare the effectivness of Scaling and Root Plannig (SRP) in association with lipo-curcumin gel (LC) respect SRP+ lipo-gel (L), SRP+ discharged (D) gel and SRP…
- Conditions
- Periodontal Diseases, Periodontal Pocket, Periodontal Attachment Loss
- Trial name
- NCT06624241
- Testing
- Lipo-Curcumin gel + SRP, Lipo gel + SRP, Discharged Gel + SRP
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- G. d'Annunzio University
Periodontal Pocket
Non-surgical Step 3 Periodontal Treatment With/Without Adjunctive Protocol - Pilot RCT.
Study conducted in patients recruited at private praxis setting after completed step 2 periodontal therapy. Residual pockets ≥4mm with positive bleeding or such >5mm randomly allocated to either conventional subgingival…
- Trial name
- NCT06438354
- Testing
- subgingival instrumentation plus Perisolv / hyaDent BG, subgingival instrumentation
- Where
- Germany
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Witten/Herdecke
Periodontal Pocket, Periodontitis
"Re-instrumentation vs Flap Surgery"
There are no studies comparing reinstrumentation and flap surgery for the treatment of residual periodontal pockets. The aim of this RCT is to compare the re-instrumentation vs the flap surgery in terms of PD reduction, CAL gain…
- Trial name
- NCT05460988
- Testing
- Flap surgery, Non surgical re-instrumentation
- Where
- Italy
- Volunteers
- 46 people
- Sponsor
- University of Florence
Periodontal Disease
Periodontal Disease Treatment of a Physically Challenged Population
Many physically handicapped patients at the dental department, Toronto Rehabilitation Institute(TRI) have considerable gingival inflammation and breath odour because of the inability to effectively handle a toothbrush.
- Trial name
- PDT (NCT01718912)
- Testing
- metronidazole-nystatin oral rinse
- Where
- Canada
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Oravital Inc
Pocket, Periodontal, Periodontitis
Impact of Minimally Non-surgical Periodontal Treatment on Residual Pockets
A double-blind randomized-controlled clinical trial is conducted in order to evaluate the impact of non-surgical periodontal treatment by means of minimally invasive approach MINST or Q-SI (quadrantwise) approach in subjects with…
- Trial name
- NCT06993519
- Testing
- Probin Pocket Depth reduction
- Where
- Italy
- Volunteers
- 64 people
- Sponsor
- University of Catania
Periodontitis Stage II, Gingival Pocket
Use of Injectable Extended Platelet-Rich Fibrin as a Local Drug Delivery in the Treatment of Stage II Periodontitis Patients
The objective of the present study is to assess the clinical effectiveness of local delivery of injectable extended platelet-rich fibrin in subgingival application when used in conjunction with scaling and root planing (SRP) in…
- Trial name
- NCT07080294
- Testing
- extended platelet rich fibrin injection in pocket, albumin injection in pocket, scaling and root planing
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Mansoura University
Periodontal Diseases, Periodontitis
Interaction Between Immune Cells and Bacteria Associated With Periodontitis
This study evaluates the interaction between host immune cells and bacteria associated with periodontitis. It comprises biological material from donors with and without periodontal disease.
- Conditions
- Periodontal Diseases, Periodontitis, Aggressive Periodontitis, Immunologic Disease
- Trial name
- NCT03225950
- Testing
- In vitro stimulation of blood with periodontitis-associated- and control bacteria, Anti-CCP- and anti-P.g.-antibodies titers, Analysis of selected single nucleotide polymorphisms (SNPs)
- Where
- 2 sites in Denmark
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Periodontal Pocket
Treatment of Periodontal Intraosseous Defects
The aim of the present study was to evaluate the impact of surgical flap design on the healing of intrabony defects treated by means periodontal regeneration. Forty patients were enrolled and allocated random in two groups.
- Trial name
- NCT04542746
- Testing
- Minimally invasive surgical technique
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Iorio Research and Dental Practice
Peri-Implantitis
Management of Peri-implantitis: Non-surgical Treatment of Peri-implantitis.
The goal of this clinical trial is to compare non-surgical treatment by mechanical debridement with air-polishing in peri-implantitis.
- Trial name
- NCT05683405
- Testing
- Non-surgical treatment of peri-implantitis with mechanical debridement, Non-surgical treatment of peri-implantitis with air polishing
- Where
- Norway
- Volunteers
- 88 people
- Sponsor
- Tannhelsetjenestens Kompetansesenter for Nord-Norge
Periodontal Diseases
Adjunctive Local Sodium Hypochlorite Gel in Non Surgical Periodontal Debridement
The aim of this study was to assess the efficacy of minimally invasive nonsurgical debridement (MINSD) of periodontal pockets with or without local amino acid buffered sodium hypochlorite (NaOCl) gel application after 6 months…
- Trial name
- NCT04399187
- Testing
- Sodium hypochlorite gel application
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Messina
Gingival Health, Metal Ceramic Restorations
The Effect of Fixed Dentures on Periodontal Tissues in Long-term.
The goal of this observational study is to to evaluate the periodontal condition around metal-ceramic crown. The main question to be answered is: whether the metal-ceramic crown is the cause of gum changes? The study offers to…
- Trial name
- NCT07611461
- Where
- Latvia
- Volunteers
- 75 people
- Sponsor
- Riga Stradins University
Periodontitis, Smokers
This a Clinical Trial to Evaluate the Efficacy of I-PRF, Povidone-Iodine and Laser as Adjuncts to Non-surgical Periodontal Treatment in Smokers and Non-Smokers Periodontitis Patients
This study is a randomized, controlled, split-mouth clinical trial designed to evaluate and compare the effectiveness of four different subgingival adjuncts used along side standard Scaling and Root Planning (SRP).
- Conditions
- Periodontitis, Smokers, Non Smokers, Periodontal Disease
- Trial name
- NCT07707063
- Testing
- Injectable Platelet-Rich Fibrin (I-PRF), Diode Laser Activation, Povidone-Iodine Irrigation (1%)
- Where
- Tunisia
- Volunteers
- 50 people
- Sponsor
- Military Hospital of Tunis