Horizontal Alveolar Ridge DeficiencyNCT07670559
Carrot Technique Versus Guided Bone Regeneration for Horizontal Ridge Deficiency in the Maxillary Esthetic Zone
A study testing Carrot Technique and Guided Bone Regeneration in people with Horizontal Alveolar Ridge Deficiency and Partial Edentulism, run by Mansoura University at 2 sites in Egypt.
Trial summary
This randomized controlled clinical trial aims to compare the effectiveness of the Carrot Technique and Guided Bone Regeneration (GBR) for the management of horizontal alveolar ridge deficiency in patients requiring implant placement in the maxillary esthetic zone. Read more about this study
- Who is it for?
- Ages 18 to 45 years
- Conditions the study is for
- Horizontal Alveolar Ridge Deficiency, Partial Edentulism
- What is being tested?
- Carrot Technique and Guided Bone Regeneration
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 20 participants
- Where
- 2 sitesEgypt
- Study dates
- 2 Aug 2025to Oct 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 45 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Patients aged 18 to 45 years. Missing a single tooth in the maxillary esthetic zone requiring implant placement.
- Good oral hygiene and patient compliance. Medically free from systemic diseases that contraindicate implant surgery. Slight to moderate horizontal alveolar ridge deficiency with a minimum ridge width of 5 mm.
- Adequate vertical bone height for implant placement. Medium to hard bone quality (D2-D3 according to Misch classification). Absence of bruxism or other parafunctional habits.
Who cannot join
- Presence of local pathological lesions (e.g., cysts or tumors) at the planned surgical site.
- Poor bone quality (D4 bone). Pregnancy. Heavy smoking. Any medical condition contraindicating implant surgery.
Trial locations and contacts
2 sites in 1 country.
Egypt2 sites
Faculty of Dentistry, Mansoura University
Al Mansurah, Dakahlia Governorate, 35511
Faculty of Dentistry, Mansoura University
Al Mansurah
About this study
Official title: Evaluation of the Carrot Technique With Simultaneous Implant Placement for Horizontal Alveolar Ridge Deficiency in the Maxillary Aesthetic Zone: A Randomized Controlled Clinical Trial.
This randomized controlled clinical trial aims to compare the effectiveness of the Carrot Technique and Guided Bone Regeneration (GBR) for the management of horizontal alveolar ridge deficiency in patients requiring implant placement in the maxillary esthetic zone. Twenty patients will be randomly allocated into two equal groups. Clinical outcomes including implant stability and soft tissue healing, as well as radiographic outcomes including alveolar ridge width, bone density, and marginal bone loss, will be evaluated using clinical examinations and cone beam computed tomography (CBCT) during a 12-month follow-up period..
Read the detailed description
The Carrot Technique is a minimally invasive approach that utilizes an autogenous bone core harvested during implant osteotomy and repositioned to augment the deficient buccal ridge. This technique may reduce donor-site morbidity while providing sufficient horizontal bone augmentation. Guided Bone Regeneration remains one of the most widely used techniques for horizontal ridge reconstruction through the use of bone substitute materials and barrier membranes.
This randomized controlled clinical trial will compare the clinical and radiographic outcomes of the Carrot Technique and GBR in patients presenting with horizontal ridge deficiency in the maxillary esthetic zone. Twenty patients requiring single-tooth implant rehabilitation will be randomly allocated into two equal groups. Group I will receive implant placement combined with the Carrot Technique, while Group II will receive implant placement combined with Guided Bone Regeneration.
Clinical evaluations will include implant stability assessed by resonance frequency analysis, soft tissue healing using the Landry Healing Index, and peri-implant inflammation using the modified sulcus bleeding index. Radiographic evaluation will be performed using cone beam computed tomography immediately after surgery and at 6 and 12 months postoperatively to assess changes in alveolar ridge width, bone density, and marginal bone loss. The study aims to determine whether the Carrot Technique provides comparable or superior outcomes to GBR for horizontal ridge augmentation associated with implant placement.
- Being tested
- Carrot Technique, Guided Bone Regeneration
- Keywords
- Dental Implant;, Horizontal Ridge Augmentation;, Alveolar Ridge Deficiency;, Guided Bone Regeneration;, Carrot Technique;, Maxillary Esthetic Zone
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Carrot TechniqueProcedure or surgery
Implant placement with simultaneous horizontal ridge augmentation using an autogenous bone core harvested from the implant osteotomy site with a trephine drill and fixed buccally using osteosynthesis screws.
Guided Bone RegenerationProcedure or surgery
Implant placement with simultaneous horizontal ridge augmentation using bone substitute material and a collagen membrane according to guided bone regeneration principles.
| Study group | Role | What they receive |
|---|---|---|
| Carrot Technique | Experimental | Implant placement with horizontal ridge augmentation using an autogenous bone core harvested with a trephine drill from the implant osteotomy site and fixed buccally using osteosynthesis screws. Receives: Procedure: Carrot Technique |
| Guided Bone Regeneration | Active comparator | Implant placement with horizontal ridge augmentation using bone substitute material and a collagen membrane according to guided bone regeneration principles. Receives: Procedure: Guided Bone Regeneration |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in Alveolar Ridge Width
Horizontal alveolar ridge width measured using cone beam computed tomography (CBCT). Changes in ridge width will be calculated by comparing measurements obtained immediately after surgery and at follow-up.
Measured: baseline and 12 Months
Secondary outcomes (5)
Marginal Bone Loss
Marginal bone loss measured radiographically using CBCT using the implant as a reference.
Measured: 12 Months
Soft Tissue Healing
Soft tissue healing assessed using the Landry Healing Index.
Measured: 1 Week, 2 Weeks, and 1 Month
Modified Sulcus Bleeding Index
Peri-implant soft tissue inflammation assessed using the Modified Sulcus Bleeding Index (mBI).
Measured: 1 Month and 12 Months
Bone Density
Buccal peri-implant bone density measured using CBCT and expressed in Hounsfield Units.
Measured: 12 Months
Implant Stability Quotient (ISQ)
Implant stability assessed using resonance frequency analysis and expressed as Implant Stability Quotient (ISQ).
Measured: At implant placement and 12 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted26 Jun 2026
- Study start2 Aug 2025
- Primary completionSep 2026 (estimated)
- Study completionOct 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Horizontal Alveolar Ridge DeficiencyStudies of the same condition, open and under way.
- More trials run by Mansoura UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Participants will be randomly assigned to receive either the Carrot Technique or Guided Bone Regeneration (GBR) during implant placement for treatment of horizontal alveolar ridge deficiency in the maxillary esthetic zone.
- Masking
- Double blind
- Who is masked
- Investigator, Outcomes assessor
- Enrolment
- 20 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Mansoura University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Sarah Elmaghraby, Mansoura University
- Investigators
- Sarah A Elmaghraby, Principal investigator, Faculty of Dentistry, Mansoura University, Mansoura, Egypt
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07670559
- Sponsor's protocol ID
- R.26.02.103
- Status last verified
- Jun 2026
- First submitted
- 22 Jun 2026
- Last updated
- 26 Jun 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 26 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Evaluation of the Carrot Technique With Simultaneous Implant Placement for Horizontal Alveolar Ridge Deficiency in the Maxillary Aesthetic Zone: A Randomized Controlled Clinical Trial.
- ClinicalTrials.gov ID
- NCT07670559
- Acronym / sponsor ID
- R.26.02.103
- Keywords
- Dental Implant;, Horizontal Ridge Augmentation;, Alveolar Ridge Deficiency;, Guided Bone Regeneration;, Carrot Technique;, Maxillary Esthetic Zone
- Study type
- Interventional
- Recruitment status
- Active, not recruiting
- Enrolment
- 20 participants (estimated)
- Lead sponsor
- Mansoura UniversityUniversity, hospital or other
- Study start
- 2 Aug 2025 (actual)
- Primary completion
- Sep 2026 (estimated)
- Study completion
- Oct 2026 (estimated)
- First posted
- 26 Jun 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This randomized controlled clinical trial aims to compare the effectiveness of the Carrot Technique and Guided Bone Regeneration (GBR) for the management of horizontal alveolar ridge deficiency in patients requiring implant placement in the maxillary esthetic zone. Twenty patients will be randomly allocated into two equal groups. Clinical outcomes including implant stability and soft tissue healing, as well as radiographic outcomes including alveolar ridge width, bone density, and marginal bone loss, will be evaluated using clinical examinations and cone beam computed tomography (CBCT) during a 12-month follow-up period..
Detailed description
The Carrot Technique is a minimally invasive approach that utilizes an autogenous bone core harvested during implant osteotomy and repositioned to augment the deficient buccal ridge. This technique may reduce donor-site morbidity while providing sufficient horizontal bone augmentation. Guided Bone Regeneration remains one of the most widely used techniques for horizontal ridge reconstruction through the use of bone substitute materials and barrier membranes.
This randomized controlled clinical trial will compare the clinical and radiographic outcomes of the Carrot Technique and GBR in patients presenting with horizontal ridge deficiency in the maxillary esthetic zone. Twenty patients requiring single-tooth implant rehabilitation will be randomly allocated into two equal groups. Group I will receive implant placement combined with the Carrot Technique, while Group II will receive implant placement combined with Guided Bone Regeneration.
Clinical evaluations will include implant stability assessed by resonance frequency analysis, soft tissue healing using the Landry Healing Index, and peri-implant inflammation using the modified sulcus bleeding index. Radiographic evaluation will be performed using cone beam computed tomography immediately after surgery and at 6 and 12 months postoperatively to assess changes in alveolar ridge width, bone density, and marginal bone loss. The study aims to determine whether the Carrot Technique provides comparable or superior outcomes to GBR for horizontal ridge augmentation associated with implant placement.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (investigator, outcomes assessor)
- Number of arms
- 2
- Model description
- Participants will be randomly assigned to receive either the Carrot Technique or Guided Bone Regeneration (GBR) during implant placement for treatment of horizontal alveolar ridge deficiency in the maxillary esthetic zone.
| Arm | Type | Receives |
|---|---|---|
| Carrot Technique | Experimental | Procedure: Carrot TechniqueImplant placement with horizontal ridge augmentation using an autogenous bone core harvested with a trephine drill from the implant osteotomy site and fixed buccally using osteosynthesis screws. |
| Guided Bone Regeneration | Active comparator | Procedure: Guided Bone RegenerationImplant placement with horizontal ridge augmentation using bone substitute material and a collagen membrane according to guided bone regeneration principles. |
Who may qualify
- Ages
- 18 to 45 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (3 listed)
- Patients aged 18 to 45 years. Missing a single tooth in the maxillary esthetic zone requiring implant placement.
- Good oral hygiene and patient compliance. Medically free from systemic diseases that contraindicate implant surgery. Slight to moderate horizontal alveolar ridge deficiency with a minimum ridge width of 5 mm.
- Adequate vertical bone height for implant placement. Medium to hard bone quality (D2-D3 according to Misch classification). Absence of bruxism or other parafunctional habits.
Key exclusion criteria (2 listed)
- Presence of local pathological lesions (e.g., cysts or tumors) at the planned surgical site.
- Poor bone quality (D4 bone). Pregnancy. Heavy smoking. Any medical condition contraindicating implant surgery.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Carrot TechniqueImplant placement with simultaneous horizontal ridge augmentation using an autogenous bone core harvested from the implant osteotomy site with a trephine drill and fixed buccally using osteosynthesis screws. | Procedure or surgery | Carrot Technique |
| Guided Bone RegenerationImplant placement with simultaneous horizontal ridge augmentation using bone substitute material and a collagen membrane according to guided bone regeneration principles. | Procedure or surgery | Guided Bone Regeneration |
Primary outcome
Change in Alveolar Ridge Width
Time frame: baseline and 12 Months
Horizontal alveolar ridge width measured using cone beam computed tomography (CBCT). Changes in ridge width will be calculated by comparing measurements obtained immediately after surgery and at follow-up.
5 secondary outcomes
Marginal Bone Loss
Time frame: 12 Months
Soft Tissue Healing
Time frame: 1 Week, 2 Weeks, and 1 Month
Modified Sulcus Bleeding Index
Time frame: 1 Month and 12 Months
Bone Density
Time frame: 12 Months
Implant Stability Quotient (ISQ)
Time frame: At implant placement and 12 months
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 26 Jun 2026.
- Individual participant dataSharing planned: No
Related trials for Horizontal Alveolar Ridge Deficiency
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Autogenous and Xenograft Bone Mix in Alveolar Ridge Reconstruction
Horizontal Alveolar Ridge Deficiency
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Comparison of Three Autogenous Bone and Xenograft Ratios for Horizontal Ridge Augmentation
Horizontal Alveolar Ridge Deficiency
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Comparison of Two Autogenous Bone and Xenograft Ratios for Horizontal Ridge Augmentation
Horizontal Alveolar Ridge Deficiency
Not yet recruiting
Shell Technique for Implant Site Development
Ridge Augmentation, Ridge Deficiency
Recruiting
Histological and Histomorphometric Assessment With Inflammatory Profile Analysis of Bone Tissue After Horizontal Ridge Augmentation Using Customized Porous Zirconia Shell
Alveolar Bone Loss, Alveolar Ridge Deficiency
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Sarah A Elmaghraby principal investigator
Faculty of Dentistry, Mansoura University, Mansoura, Egypt
2 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Carrot Technique and Guided Bone Regeneration in people with Horizontal Alveolar Ridge Deficiency and Partial Edentulism, run by Mansoura University at 2 sites in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 26 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 2 sites in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in Alveolar Ridge Width (time frame: baseline and 12 Months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 26 Jun 2026.