Vaccine HesitancyNCT07672886
Parents' Knowledge and Attitudes Towards Vaccinating Their Children
A study testing questionnaire application in people with Vaccine Hesitancy, run by Iuliu Hatieganu University of Medicine and Pharmacy.
Trial summary
Purpose: To identify and evaluate the factors that influence parents' attitudes towards vaccination. Objectives: 1. To assess parents' level of knowledge about vaccines 2. To assess parents' attitudes and behavior regarding vaccine administration. 3. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Vaccine Hesitancy
- What is being tested?
- questionnaire application
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 200 participants
- Where
- No sites listed yet
- Study dates
- 1 Jul 2026to 1 Jul 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- parents of patients under 18 years of age admitted to the Emergency Children's Hospital, Cluj-Napoca, Paediatrics Clinic III during January -sept 2026
Who cannot join
- parent of patients under 18 years who refuse to participate or to fill in the questionnaire and the consent form
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
About this study
Purpose: To identify and evaluate the factors that influence parents' attitudes towards vaccination.
Objectives:
Read more
- To assess parents' level of knowledge about vaccines
- To assess parents' attitudes and behavior regarding vaccine administration.
- To observe whether there is a link between various socio-demographic factors and their knowledge about vaccines.
- To assess the relationship and communication between doctors and parents.
- To evaluate the influence of the COVID-19 pandemic on parents' trust in vaccines.
Method Distribution of questionnaires to parents of patients under 18 years of age admitted in the Emergency Children's Hospital, Cluj-Napoca, Paediatrics Clinic III. Collection of clinical data by applying questionnaires completed voluntarily by parents
Read the detailed description
Parents' knowledge and attitudes towards vaccinating their children
Introduction Vaccines administered in childhood save 2-3 million lives globally each year. They have contributed substantially to the decline in infant morbidity and mortality rates over time and represent the most cost-effective method of reducing childhood illness.
A high vaccination rate among the population protects both those who have received the vaccine and those who have not, through the phenomenon of herd immunity. Maintaining protection plays an important role in the development of the paediatric population. Early childhood infections can affect the growth and development of children, impacting the health and cognitive abilities of future adults. Although vaccines reduce morbidity and mortality, many parents do not vaccinate their children. In developing countries, the main causes of non-vaccination are low socio-economic status, poor parental education and limited access to medical services. On the other hand, in more developed countries, parents, despite having easy access to vaccines and information, choose not to vaccinate their children.
In order to increase vaccination rates, it is necessary to understand where parents' beliefs come from. Parents' refusal to vaccinate their children has been associated with: the costs involved in the vaccination process, fear of adverse effects, both immediate and long-term, the belief that vaccines are ineffective, and various attitudes. These include: lack of trust in the state authorities responsible for implementing vaccination programmes, religious conflicts, and the idea of over stimulating the child's immune system with "too many vaccines".
Recently, a decisive factor has emerged that influences parents' opinions: social media. Studies conducted to date have shown the impact of anti-vaccine content posted online on the decline in vaccination rates.
Hypothesis: The decline in vaccination rates among the paediatric population is occurring in both developed countries and low socio-economic environments, with parental attitudes being the main decisive factor.
Purpose: To identify and evaluate the factors that influence parents' attitudes towards vaccination.
Objectives:
- To assess parents' level of knowledge about vaccines
- To assess parents' attitudes and behavior regarding vaccine administration.
- To observe whether there is a link between various socio-demographic factors and their knowledge about vaccines.
- To assess the relationship and communication between doctors and parents.
- To evaluate the influence of the COVID-19 pandemic on parents' trust in vaccines.
Research area: research into parents' attitudes and knowledge about vaccines and their interaction with healthcare professionals.
Study type: descriptive, cross-sectional, representative sample study. Target population: parents of children under 18 years of age evaluated at the Emergency Children's Hospital, Cluj-Napoca, Paediatrics Clinic III, between January- Sept 2026.
Representative sample data collection
Materials and methods:
Distribution of questionnaires to parents of patients under 18 years of age admitted in the Emergency Children's Hospital, Cluj-Napoca, Paediatrics Clinic III. Collection of clinical data by applying questionnaires completed voluntarily by parents. By completing the informed consent form, parents gave their consent to participate in this study.
Clinical data to be recorded: gender, age, place of residence, level of education, profession, age of children, vaccination status of parents and children. Collection of data on: parents' knowledge and attitudes towards vaccines, the doctor-parent relationship and parents' level of trust in doctors, and knowledge about infections. Distribution of questionnaires to family doctors and paediatricians to assess the communication relationship between doctors and parents in the context of vaccines.
Descriptive statistics: Data will be stored in accordance with legal provisions for the protection of patients' identity and personal data. Statistical analysis of the data will be performed using Microsoft Excel and SPSS.
The results and conclusions will be disseminated through the publication of articles in scientific journals.
- Conditions
- Vaccine Hesitancy
- Being tested
- questionnaire application
- Medical subject headings
- Vaccination Hesitancy
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
questionnaire applicationOther
questionnaire application
| Study group | Role | What they receive |
|---|---|---|
| Parents questionaires | Experimental | Distribution of questionnaires to parents of patients under 18 years of age admitted in the Emergency Children's Hospital, Cluj-Napoca Receives: Other: questionnaire application |
What is being measured
The primary outcome is the main question the study is designed to answer.
The questionnaire administered to parents and caregivers, entitled "Parents' Knowledge and Attitudes Toward Childhood Vaccination", was designed to identify the factors influencing vaccine acceptance, hesitancy, and refusal.
The questionnaire items were structured into the following main domains:
Sociodemographic characteristics Vaccination status Attitudes and motivations Sources of information and trust Data obtained from the questionnaires will be analysed. The distribution of quantitative variables will be assessed using the Shapiro-Wilk test.
Categorical variables will be expressed as absolute frequencies and percentages. Associations between categorical variables were evaluated using the Chi-square test. Comparisons of non-parametric quantitative variables between two independent groups were performed using the Mann-Whitney U test.
Measured: bseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted29 Jun 2026
- Study start1 Jul 2026 (estimated)
- Primary completion1 Jul 2026 (estimated)
- Study completion1 Jul 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Vaccine HesitancyStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 200 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Sas Valentina, Iuliu Hatieganu University of Medicine and Pharmacy
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07672886
- Sponsor's protocol ID
- DEP309/15.10.2025
- Status last verified
- Jun 2026
- First submitted
- 26 Mar 2026
- Last updated
- 29 Jun 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 29 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Parents' Knowledge and Attitudes Towards Vaccinating Their Children
- ClinicalTrials.gov ID
- NCT07672886
- Acronym / sponsor ID
- DEP309/15.10.2025
- Conditions
- Vaccine Hesitancy
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 200 participants (estimated)
- Lead sponsor
- Iuliu Hatieganu University of Medicine and PharmacyUniversity, hospital or other
- Study start
- 1 Jul 2026 (estimated)
- Primary completion
- 1 Jul 2026 (estimated)
- Study completion
- 1 Jul 2026 (estimated)
- First posted
- 29 Jun 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Purpose: To identify and evaluate the factors that influence parents' attitudes towards vaccination.
Objectives:
- To assess parents' level of knowledge about vaccines
- To assess parents' attitudes and behavior regarding vaccine administration.
- To observe whether there is a link between various socio-demographic factors and their knowledge about vaccines.
- To assess the relationship and communication between doctors and parents.
- To evaluate the influence of the COVID-19 pandemic on parents' trust in vaccines.
Method Distribution of questionnaires to parents of patients under 18 years of age admitted in the Emergency Children's Hospital, Cluj-Napoca, Paediatrics Clinic III. Collection of clinical data by applying questionnaires completed voluntarily by parents
Detailed description
Parents' knowledge and attitudes towards vaccinating their children
Introduction Vaccines administered in childhood save 2-3 million lives globally each year. They have contributed substantially to the decline in infant morbidity and mortality rates over time and represent the most cost-effective method of reducing childhood illness.
A high vaccination rate among the population protects both those who have received the vaccine and those who have not, through the phenomenon of herd immunity. Maintaining protection plays an important role in the development of the paediatric population. Early childhood infections can affect the growth and development of children, impacting the health and cognitive abilities of future adults. Although vaccines reduce morbidity and mortality, many parents do not vaccinate their children. In developing countries, the main causes of non-vaccination are low socio-economic status, poor parental education and limited access to medical services. On the other hand, in more developed countries, parents, despite having easy access to vaccines and information, choose not to vaccinate their children.
In order to increase vaccination rates, it is necessary to understand where parents' beliefs come from. Parents' refusal to vaccinate their children has been associated with: the costs involved in the vaccination process, fear of adverse effects, both immediate and long-term, the belief that vaccines are ineffective, and various attitudes. These include: lack of trust in the state authorities responsible for implementing vaccination programmes, religious conflicts, and the idea of over stimulating the child's immune system with "too many vaccines".
Recently, a decisive factor has emerged that influences parents' opinions: social media. Studies conducted to date have shown the impact of anti-vaccine content posted online on the decline in vaccination rates.
Hypothesis: The decline in vaccination rates among the paediatric population is occurring in both developed countries and low socio-economic environments, with parental attitudes being the main decisive factor.
Purpose: To identify and evaluate the factors that influence parents' attitudes towards vaccination.
Objectives:
- To assess parents' level of knowledge about vaccines
- To assess parents' attitudes and behavior regarding vaccine administration.
- To observe whether there is a link between various socio-demographic factors and their knowledge about vaccines.
- To assess the relationship and communication between doctors and parents.
- To evaluate the influence of the COVID-19 pandemic on parents' trust in vaccines.
Research area: research into parents' attitudes and knowledge about vaccines and their interaction with healthcare professionals.
Study type: descriptive, cross-sectional, representative sample study. Target population: parents of children under 18 years of age evaluated at the Emergency Children's Hospital, Cluj-Napoca, Paediatrics Clinic III, between January- Sept 2026.
Representative sample data collection
Materials and methods:
Distribution of questionnaires to parents of patients under 18 years of age admitted in the Emergency Children's Hospital, Cluj-Napoca, Paediatrics Clinic III. Collection of clinical data by applying questionnaires completed voluntarily by parents. By completing the informed consent form, parents gave their consent to participate in this study.
Clinical data to be recorded: gender, age, place of residence, level of education, profession, age of children, vaccination status of parents and children. Collection of data on: parents' knowledge and attitudes towards vaccines, the doctor-parent relationship and parents' level of trust in doctors, and knowledge about infections. Distribution of questionnaires to family doctors and paediatricians to assess the communication relationship between doctors and parents in the context of vaccines.
Descriptive statistics: Data will be stored in accordance with legal provisions for the protection of patients' identity and personal data. Statistical analysis of the data will be performed using Microsoft Excel and SPSS.
The results and conclusions will be disseminated through the publication of articles in scientific journals.
Study design
- Primary purpose
- Other
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Parents questionaires | Experimental | Other: questionnaire applicationDistribution of questionnaires to parents of patients under 18 years of age admitted in the Emergency Children's Hospital, Cluj-Napoca |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (1 listed)
- parents of patients under 18 years of age admitted to the Emergency Children's Hospital, Cluj-Napoca, Paediatrics Clinic III during January -sept 2026
Key exclusion criteria (1 listed)
- parent of patients under 18 years who refuse to participate or to fill in the questionnaire and the consent form
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| questionnaire applicationquestionnaire application | Other | Parents questionaires |
Primary outcome
The questionnaire administered to parents and caregivers, entitled "Parents' Knowledge and Attitudes Toward Childhood Vaccination", was designed to identify the factors influencing vaccine acceptance, hesitancy, and refusal.
Time frame: bseline
The questionnaire items were structured into the following main domains: Sociodemographic characteristics Vaccination status Attitudes and motivations Sources of information and trust Data obtained from the questionnaires will be analysed. The distribution of quantitative variables will be assessed using the Shapiro-Wilk test. Categorical variables will be expressed as absolute frequencies and percentages. Associations between categorical variables were evaluated using the Chi-square test. Comparisons of non-parametric quantitative variables between two independent groups were performed using the Mann-Whitney U test.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 29 Jun 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Questions about this trial
What is this clinical trial studying?
A study testing questionnaire application in people with Vaccine Hesitancy, run by Iuliu Hatieganu University of Medicine and Pharmacy.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 29 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Valentina Sas (+40740139979, sas.valentina@umfcluj.ro), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
The questionnaire administered to parents and caregivers, entitled "Parents' Knowledge and Attitudes Toward Childhood Vaccination", was designed to identify the factors influencing vaccine acceptance, hesitancy, and refusal. (time frame: bseline). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 29 Jun 2026.