Disorders of Gut-brain InteractionNCT07676136
A Pilot Study Using Gut-Directed Hypnotherapy for Hospitalized Patients
A study testing Gut directed hypnotherapy via telephone intervention and Educational recording in people with Disorders of Gut-brain Interaction and Inflammatory Bowel Disease (IBD), run by Stanford University at 1 site in United States.
Trial summary
The purpose of the study is to compare the effectiveness of recorded gut-directed hypnosis to an educational recording in people with chronic problems in their gastrointestinal (GI) system. Patients who are hospitalized at Stanford Hospital for worsening pain and/or nausea will be considered for enrollment. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Disorders of Gut-brain Interaction, Inflammatory Bowel Disease (IBD), Irritable Bowel Syndrome
- What is being tested?
- Gut directed hypnotherapy via telephone intervention and Educational recording
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 26 participants
- Where
- 1 siteUnited States
- Study dates
- Jul 2026to Jul 2028
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Adults admitted to the GI inpatient service with expected length of stay >24 hours
- Prior diagnosis of a disorder of gut-brain interaction, esophageal disorder, or inflammatory bowel disease
- Reason for hospitalization related to symptom management for exacerbation of visceral pain and/or nausea.
Who cannot join
- Currently using hypnosis
- severe developmental delay or cognitive impairment
- serious mental illness (i.e. psychosis or dissociation)
- hearing impairment
- Non-English speaking
- enrolled in another trial for GI symptom management
- admitted for GI procedure
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
About this study
The purpose of the study is to compare the effectiveness of recorded gut-directed hypnosis to an educational recording in people with chronic problems in their gastrointestinal (GI) system. Patients who are hospitalized at Stanford Hospital for worsening pain and/or nausea will be considered for enrollment.
- Conditions
- Disorders of Gut-brain Interaction, Inflammatory Bowel Disease (IBD), Irritable Bowel Syndrome, Abdominal Pain, Esophageal Disease
- Being tested
- Gut directed hypnotherapy via telephone intervention, Educational recording
- Keywords
- hypnosis
- Medical subject headings
- Inflammatory Bowel Diseases, Irritable Bowel Syndrome, Abdominal Pain, Esophageal Diseases
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Gut directed hypnotherapy via telephone interventionBehavioural
Participants will undergo a self-directed gut-directed hypnosis intervention over the telephone.
Educational recordingBehavioural
Participants will listen to educational material over the telephone about their gastrointestinal symptoms.
| Study group | Role | What they receive |
|---|---|---|
| Hypnosis | Experimental | Participants will undergo gut-directed hypnotherapy via a phone intervention (10 minute recording, at least once daily while hospitalized) and for as much as participant would like for the 3 month duration of the study. Receives: Behavioral: Gut directed hypnotherapy via telephone intervention |
| Education | Sham comparator | Participants will listen to educational recording (10 minute recording, at least once daily while hospitalized) and for as much as participant would like for the 3 month duration of the study. Receives: Behavioral: Educational recording |
What is being measured
The primary outcome is the main question the study is designed to answer.
Recruitment rate
Recruitment rate is the proportion enrolled among eligible patients approached.
Measured: Up to 1 year.
Number of participants who adhered to intervention
Proportion of participants completing ≥1 hypnosis session during hospitalization and total number of listens
Measured: 3 months.
Retention rate
Retention rate is defined as survey completion at baseline, 1 week, 1 month, and 3 months.
Measured: 3 months.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted30 Jun 2026
- Study startJul 2026 (estimated)
- Primary completionJul 2027 (estimated)
- Study completionJul 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Disorders of Gut-brain InteractionStudies of the same condition, open and under way.
- More trials run by Stanford UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 26 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Stanford University
- Sponsor type
- University, hospital or other
- Collaborators
- American College of Gastroenterology
- Responsible party
- Principal investigator, Irene Sonu, Stanford University
- Investigators
- Irene Sonu, MD, Principal investigator, Stanford University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07676136
- Sponsor's protocol ID
- 83851
- Status last verified
- Jun 2026
- First submitted
- 23 Jun 2026
- Last updated
- 30 Jun 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 30 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- A Pilot Study Using Gut-Directed Hypnotherapy for Hospitalized Patients
- ClinicalTrials.gov ID
- NCT07676136
- Acronym / sponsor ID
- 83851
- Conditions
- Disorders of Gut-brain Interaction, Inflammatory Bowel Disease (IBD), Irritable Bowel Syndrome, Abdominal Pain, Esophageal Disease
- Keywords
- hypnosis
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 26 participants (estimated)
- Lead sponsor
- Stanford UniversityUniversity, hospital or other
- Collaborators
- American College of Gastroenterology
- Study start
- Jul 2026 (estimated)
- Primary completion
- Jul 2027 (estimated)
- Study completion
- Jul 2028 (estimated)
- First posted
- 30 Jun 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of the study is to compare the effectiveness of recorded gut-directed hypnosis to an educational recording in people with chronic problems in their gastrointestinal (GI) system. Patients who are hospitalized at Stanford Hospital for worsening pain and/or nausea will be considered for enrollment.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Hypnosis | Experimental | Behavioral: Gut directed hypnotherapy via telephone interventionParticipants will undergo gut-directed hypnotherapy via a phone intervention (10 minute recording, at least once daily while hospitalized) and for as much as participant would like for the 3 month duration of the study. |
| Education | Sham comparator | Behavioral: Educational recordingParticipants will listen to educational recording (10 minute recording, at least once daily while hospitalized) and for as much as participant would like for the 3 month duration of the study. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- Adults admitted to the GI inpatient service with expected length of stay >24 hours
- Prior diagnosis of a disorder of gut-brain interaction, esophageal disorder, or inflammatory bowel disease
- Reason for hospitalization related to symptom management for exacerbation of visceral pain and/or nausea.
Key exclusion criteria (7 listed)
- Currently using hypnosis
- severe developmental delay or cognitive impairment
- serious mental illness (i.e. psychosis or dissociation)
- hearing impairment
- Non-English speaking
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Gut directed hypnotherapy via telephone interventionParticipants will undergo a self-directed gut-directed hypnosis intervention over the telephone. | Behavioural | Hypnosis |
| Educational recordingParticipants will listen to educational material over the telephone about their gastrointestinal symptoms. | Behavioural | Education |
Primary outcome
Recruitment rate
Time frame: Up to 1 year.
Recruitment rate is the proportion enrolled among eligible patients approached.
Number of participants who adhered to intervention
Time frame: 3 months.
Proportion of participants completing ≥1 hypnosis session during hospitalization and total number of listens
Retention rate
Time frame: 3 months.
Retention rate is defined as survey completion at baseline, 1 week, 1 month, and 3 months.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 30 Jun 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Irene Sonu, MD principal investigator
Stanford University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Gut directed hypnotherapy via telephone intervention and Educational recording in people with Disorders of Gut-brain Interaction and Inflammatory Bowel Disease (IBD), run by Stanford University at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 30 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Recruitment rate (time frame: Up to 1 year.). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 30 Jun 2026.