StrokeNCT07685691
Relationship Between Clinical Status and Nerve Conduction Test Findings in Patients With Unilateral Hemiplegia
An observational study of Stroke and Hemiplegia, run by Baskent University at 1 site in Turkey (Türkiye).
Trial summary
Stroke-related hemiplegia may be accompanied by peripheral nerve conduction abnormalities, which may contribute to motor impairment and functional limitations. However, the frequency of these abnormalities and their relationship with clinical status have not been fully characterized. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Stroke, Hemiplegia, Intracranial Hemorrhage, Spontaneous
- What is being tested?
- Nerve Conduction Study
- How many people
- 72 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 4 Oct 2024to 24 Jun 2026
- How long will I take part?
- 30 Days
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Adults with unilateral hemiplegia secondary to ischemic or hemorrhagic stroke who were recruited from the Department of Physical Medicine and Rehabilitation at a single tertiary care center. All participants underwent standardized nerve conduction studies and clinical assessments according to the study protocol.
Who may be able to join
- Adults (≥18 years of age).
- Unilateral hemiplegia secondary to ischemic or hemorrhagic stroke, or intracranial hemorrhage.
- Ability to undergo standardized nerve conduction studies and clinical assessments.
- Provision of written informed consent.
Who cannot join
- Bilateral hemiplegia.
- Hemiplegia secondary to benign or malignant intracranial tumors.
- Upper or lower extremity fracture, amputation, skin lesions preventing electrophysiological testing, or diagnosed peripheral vascular disease.
- Concomitant neurological disorders that may affect motor function or peripheral nerve conduction (e.g., Parkinson's disease, multiple sclerosis, encephalitis).
- Contraindications to nerve conduction studies (e.g., cardiac pacemaker or inability to safely undergo the examination).
- Inability to cooperate with or tolerate nerve conduction studies.
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
Başkent University Adana Dr. Turgut Noyan Application and Research Center
Adana, 01250
About this study
Official title: Prevalence of Peripheral Nerve Conduction Abnormalities and Their Association With Clinical Scores in Patients With Hemiplegia
Stroke-related hemiplegia may be accompanied by peripheral nerve conduction abnormalities, which may contribute to motor impairment and functional limitations. However, the frequency of these abnormalities and their relationship with clinical status have not been fully characterized. This single-center observational study aims to evaluate the frequency of peripheral nerve conduction abnormalities identified by nerve conduction studies in patients with unilateral hemiplegia and to examine their association with motor and functional clinical assessment scores. The findings may contribute to a better understanding of peripheral nerve involvement in stroke rehabilitation.
Read the detailed description
This is a single-center observational study designed to evaluate peripheral nerve conduction abnormalities in patients with unilateral hemiplegia following stroke. Participants undergo standardized nerve conduction studies together with routine clinical assessments, including validated measures of motor recovery and functional status. The study aims to describe the frequency of peripheral nerve conduction abnormalities within the study population and to examine their association with clinical assessment scores. The results may improve the understanding of peripheral nerve involvement in patients with hemiplegia and provide information that may be useful for rehabilitation practice.
- Conditions
- Stroke, Hemiplegia, Intracranial Hemorrhage, Spontaneous
- Being tested
- Nerve Conduction Study
- Keywords
- nerve conduction study, Electrophysiology, Fugl-Meyer Assessment, Rehabilitation
- Medical subject headings
- Stroke, Hemiplegia, Intracranial Hemorrhages
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Nerve Conduction StudyDiagnostic test
Also called NCS
Standardized motor and sensory nerve conduction studies were performed to evaluate peripheral nerve conduction abnormalities in patients with unilateral post-stroke hemiplegia. The test was used as a diagnostic assessment and was not part of a therapeutic intervention.
| Study group | Role | What they receive |
|---|---|---|
| Patients With Unilateral Post-Stroke Hemiplegia | Patients with unilateral post-stroke hemiplegia who underwent standardized nerve conduction studies and clinical assessments, including motor and functional outcome measures. Receives: Diagnostic Test: Nerve Conduction Study |
What is being measured
The primary outcome is the main question the study is designed to answer.
Association Between Peripheral Nerve Conduction Abnormalities and Clinical Assessment Scores
To evaluate the association between peripheral nerve conduction abnormalities identified by standardized nerve conduction studies and motor and functional outcome measures in patients with unilateral hemiplegia secondary to ischemic or hemorrhagic stroke. Peripheral nerve conduction abnormalities identified by standardized nerve conduction studies will also be described.
Measured: Baseline
Secondary outcomes (4)
Fugl-Meyer Assessment (FMA) Score (Upper and Lower Extremities)
Association between peripheral nerve conduction abnormalities and motor impairment assessed using the Fugl-Meyer Assessment.
Measured: Baseline
Functional Independence Measure (FIM) Score
Association between peripheral nerve conduction abnormalities and functional independence measured using the Functional Independence Measure.
Measured: Baseline
Timed Up and Go Test (TUG)
Association between peripheral nerve conduction abnormalities and mobility performance assessed using the Timed Up and Go test.
Measured: Baseline
Tetrax Fall Index
The Fall Index was assessed using the Tetrax static posturography system. Higher scores indicate a greater estimated risk of falling.
Measured: At study enrollment (baseline)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted6 Jul 2026
- Study start4 Oct 2024
- Primary completion20 May 2026
- Study completion24 Jun 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for StrokeStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 72 participants (actual)
- Target duration
- 30 Days
Sponsor and investigators
- Lead sponsor
- Baskent University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07685691
- Sponsor's protocol ID
- BASKENT UNIVERSITY KA24/315
- Status last verified
- Jul 2026
- First submitted
- 29 Jun 2026
- Last updated
- 29 Jul 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided: A decision regarding the sharing of individual participant data has not yet been made. Data sharing will be considered after completion of the study and publication of the primary results, in accordance with institutional policies, ethical requirements, and applicable regulations.
Study at a glance
From the registry record, last updated by the sponsor on 29 Jul 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Prevalence of Peripheral Nerve Conduction Abnormalities and Their Association With Clinical Scores in Patients With Hemiplegia
- ClinicalTrials.gov ID
- NCT07685691
- Acronym / sponsor ID
- BASKENT UNIVERSITY KA24/315
- Conditions
- Stroke, Hemiplegia, Intracranial Hemorrhage, Spontaneous
- Keywords
- nerve conduction study, Electrophysiology, Fugl-Meyer Assessment, Rehabilitation
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 72 participants (actual)
- Lead sponsor
- Baskent UniversityUniversity, hospital or other
- Study start
- 4 Oct 2024 (actual)
- Primary completion
- 20 May 2026 (actual)
- Study completion
- 24 Jun 2026 (actual)
- First posted
- 6 Jul 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Stroke-related hemiplegia may be accompanied by peripheral nerve conduction abnormalities, which may contribute to motor impairment and functional limitations. However, the frequency of these abnormalities and their relationship with clinical status have not been fully characterized. This single-center observational study aims to evaluate the frequency of peripheral nerve conduction abnormalities identified by nerve conduction studies in patients with unilateral hemiplegia and to examine their association with motor and functional clinical assessment scores. The findings may contribute to a better understanding of peripheral nerve involvement in stroke rehabilitation.
Detailed description
This is a single-center observational study designed to evaluate peripheral nerve conduction abnormalities in patients with unilateral hemiplegia following stroke. Participants undergo standardized nerve conduction studies together with routine clinical assessments, including validated measures of motor recovery and functional status. The study aims to describe the frequency of peripheral nerve conduction abnormalities within the study population and to examine their association with clinical assessment scores. The results may improve the understanding of peripheral nerve involvement in patients with hemiplegia and provide information that may be useful for rehabilitation practice.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Target follow-up
- 30 Days
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Patients With Unilateral Post-Stroke Hemiplegia | – | Diagnostic Test: Nerve Conduction StudyPatients with unilateral post-stroke hemiplegia who underwent standardized nerve conduction studies and clinical assessments, including motor and functional outcome measures. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Adults with unilateral hemiplegia secondary to ischemic or hemorrhagic stroke who were recruited from the Department of Physical Medicine and Rehabilitation at a single tertiary care center. All participants underwent standardized nerve conduction studies and clinical assessments according to the study protocol.
Key inclusion criteria (4 listed)
- Adults (≥18 years of age).
- Unilateral hemiplegia secondary to ischemic or hemorrhagic stroke, or intracranial hemorrhage.
- Ability to undergo standardized nerve conduction studies and clinical assessments.
- Provision of written informed consent.
Key exclusion criteria (6 listed)
- Bilateral hemiplegia.
- Hemiplegia secondary to benign or malignant intracranial tumors.
- Upper or lower extremity fracture, amputation, skin lesions preventing electrophysiological testing, or diagnosed peripheral vascular disease.
- Concomitant neurological disorders that may affect motor function or peripheral nerve conduction (e.g., Parkinson's disease, multiple sclerosis, encephalitis).
- Contraindications to nerve conduction studies (e.g., cardiac pacemaker or inability to safely undergo the examination).
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Nerve Conduction StudyAlso: NCSStandardized motor and sensory nerve conduction studies were performed to evaluate peripheral nerve conduction abnormalities in patients with unilateral post-stroke hemiplegia. The test was used as a diagnostic assessment and was not part of a therapeutic intervention. | Diagnostic test | Patients With Unilateral Post-Stroke Hemiplegia |
Primary outcome
Association Between Peripheral Nerve Conduction Abnormalities and Clinical Assessment Scores
Time frame: Baseline
To evaluate the association between peripheral nerve conduction abnormalities identified by standardized nerve conduction studies and motor and functional outcome measures in patients with unilateral hemiplegia secondary to ischemic or hemorrhagic stroke. Peripheral nerve conduction abnormalities identified by standardized nerve conduction studies will also be described.
4 secondary outcomes
Fugl-Meyer Assessment (FMA) Score (Upper and Lower Extremities)
Time frame: Baseline
Functional Independence Measure (FIM) Score
Time frame: Baseline
Timed Up and Go Test (TUG)
Time frame: Baseline
Tetrax Fall Index
Time frame: At study enrollment (baseline)
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 29 Jul 2026.
- Individual participant dataSharing planned: Undecided. A decision regarding the sharing of individual participant data has not yet been made. Data sharing will be considered after completion of the study and publication of the primary results, in accordance with institutional policies, ethical requirements, and applicable regulations.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Stroke and Hemiplegia, run by Baskent University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 29 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Association Between Peripheral Nerve Conduction Abnormalities and Clinical Assessment Scores (time frame: Baseline). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 29 Jul 2026.