HysterectomyCOFFEE-LHNCT07686510
Coffee Consumption After Laparoscopic Hysterectomy
A study testing Postoperative Coffee Consumption in people with Hysterectomy and Gastrointestinal Motility Disorder, run by Istanbul Medipol University Hospital at 1 site in Turkey (Türkiye).
Trial summary
Postoperative ileus and delayed bowel recovery remain common concerns following laparoscopic hysterectomy despite enhanced recovery protocols. Coffee consumption has been suggested as a simple, safe, and inexpensive intervention that may stimulate gastrointestinal motility and accelerate postoperative recovery. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Hysterectomy, Gastrointestinal Motility Disorder, Postoperative Ileus
- What is being tested?
- Postoperative Coffee Consumption
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 50 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 12 May 2025to 25 Oct 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Women aged 18 years or older.
- Scheduled for elective laparoscopic hysterectomy.
- Able to consume oral fluids according to the ERAS protocol.
- Able to communicate in Turkish.
- Willing to participate and provide written informed consent.
Who cannot join
- Emergency surgery.
- Known allergy or intolerance to coffee or caffeine.
- Gastrointestinal diseases or conditions affecting bowel motility.
- Postoperative complications requiring intensive care or preventing oral intake.
- Withdrawal of informed consent at any stage of the study.
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
Istanbul Bağcılar Training and Research Hospital
Istanbul, 34810
About this study
Official title: Effect of Postoperative Coffee Consumption on Bowel Motility and Length of Hospital Stay Following Laparoscopic Hysterectomy: A Randomized Controlled Trial
Postoperative ileus and delayed bowel recovery remain common concerns following laparoscopic hysterectomy despite enhanced recovery protocols. Coffee consumption has been suggested as a simple, safe, and inexpensive intervention that may stimulate gastrointestinal motility and accelerate postoperative recovery. This randomized controlled trial aims to evaluate the effect of postoperative coffee consumption on bowel function recovery and length of hospital stay in women undergoing laparoscopic hysterectomy. Eligible participants are randomly assigned to either a coffee intervention group receiving standard postoperative care plus coffee at predetermined postoperative time points or a control group receiving standard postoperative care alone. The primary objective is to determine whether postoperative coffee consumption improves bowel recovery and shortens hospitalization.
Read the detailed description
Laparoscopic hysterectomy is one of the most commonly performed minimally invasive gynecological procedures. Although enhanced recovery after surgery (ERAS) protocols have improved postoperative outcomes, delayed gastrointestinal recovery and postoperative ileus continue to affect patient recovery, comfort, and hospital length of stay.
Coffee contains several bioactive compounds that may stimulate gastrointestinal motility through multiple physiological mechanisms, including increased gastrin secretion, activation of the gastrocolic reflex, and enhanced colonic motor activity. Previous clinical studies have suggested that postoperative coffee consumption may accelerate bowel function recovery after abdominal surgery; however, evidence specific to laparoscopic hysterectomy remains limited.
This single-center, randomized controlled trial evaluates the effectiveness of postoperative coffee consumption in women undergoing laparoscopic hysterectomy. Fifty eligible participants are randomly allocated in a 1:1 ratio to either an intervention group or a control group using block randomization. Participants in the intervention group receive standard postoperative care together with 100 mL of soluble coffee prepared with hot water at postoperative hours 6, 12, and 18, whereas participants in the control group receive standard postoperative care alone.
The study evaluates postoperative bowel recovery by assessing bowel sounds, passage of flatus, passage of stool, abdominal distension, nausea, vomiting, distension-related pain, and length of hospital stay. The findings are expected to provide evidence regarding a simple, low-cost, and feasible nursing intervention that may improve postoperative recovery following laparoscopic hysterectomy.
- Being tested
- Postoperative Coffee Consumption
- Keywords
- Laparoscopic Hysterectomy, Coffee, ERAS, Nursing Intervention, Postoperative Recovery
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Postoperative Coffee ConsumptionBehavioural
Participants received 100 mL of hot soluble coffee prepared with hot water at postoperative hours 6, 12, and 18 in addition to standard postoperative ERAS care.
| Study group | Role | What they receive |
|---|---|---|
| Coffee Group | Experimental | Participants received standard postoperative care plus 100 mL of soluble coffee prepared with hot water at postoperative 6, 12, and 18 hours. Receives: Behavioral: Postoperative Coffee Consumption |
| Control Group | No intervention | Participants received standard postoperative care according to institutional clinical practice without postoperative coffee consumption. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Time to First Passage of Flatus
Time from the end of surgery to the first passage of flatus, recorded in hours.
Measured: From the end of surgery until the first passage of flatus, assessed for up to 72 hours after surgery.
Secondary outcomes (3)
Time to First Defecation
Time from the end of surgery to the first bowel movement.
Measured: From the end of surgery until the first bowel movement, assessed for up to 72 hours after surgery.
Time to First Bowel Sounds
Time from the end of surgery to the first audible bowel sounds.
Measured: From the end of surgery until the first bowel sounds are detected, assessed for up to 72 hours after surgery.
Length of Hospital Stay
Duration of hospitalization from surgery until discharge.
Measured: From the date of surgery until hospital discharge, assessed for up to 5 days after surgery.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted7 Jul 2026
- Study start12 May 2025
- Primary completion25 Oct 2025
- Study completion25 Oct 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for HysterectomyStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Participants were randomly assigned in a 1:1 ratio to either the intervention or control group using block randomization. The intervention group received postoperative coffee in addition to standard postoperative care, whereas the control group received standard postoperative care alone.
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 50 participants (actual)
Sponsor and investigators
- Lead sponsor
- Istanbul Medipol University Hospital
- Sponsor type
- University, hospital or other
- Collaborators
- Bagcilar Training and Research Hospital
- Responsible party
- Principal investigator, muzeyyen ataseven, Istanbul Medipol University Hospital
- Investigators
- Müzeyyen Ataseven, PhD,RN, Principal investigator, Istanbul Medipol University, Faculty of Health Sciences
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07686510
- Sponsor's protocol ID
- LHCOFFEE2025
- Acronym
- COFFEE-LH
- Status last verified
- Jul 2026
- First submitted
- 29 Jun 2026
- Last updated
- 7 Jul 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Individual participant data (IPD) will not be shared. The study did not include a data-sharing plan, and participant confidentiality will be maintained.
Study at a glance
From the registry record, last updated by the sponsor on 7 Jul 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effect of Postoperative Coffee Consumption on Bowel Motility and Length of Hospital Stay Following Laparoscopic Hysterectomy: A Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT07686510
- Acronym / sponsor ID
- COFFEE-LH / LHCOFFEE2025
- Keywords
- Laparoscopic Hysterectomy, Coffee, ERAS, Nursing Intervention, Postoperative Recovery
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 50 participants (actual)
- Lead sponsor
- Istanbul Medipol University HospitalUniversity, hospital or other
- Collaborators
- Bagcilar Training and Research Hospital
- Study start
- 12 May 2025 (actual)
- Primary completion
- 25 Oct 2025 (actual)
- Study completion
- 25 Oct 2025 (actual)
- First posted
- 7 Jul 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Postoperative ileus and delayed bowel recovery remain common concerns following laparoscopic hysterectomy despite enhanced recovery protocols. Coffee consumption has been suggested as a simple, safe, and inexpensive intervention that may stimulate gastrointestinal motility and accelerate postoperative recovery. This randomized controlled trial aims to evaluate the effect of postoperative coffee consumption on bowel function recovery and length of hospital stay in women undergoing laparoscopic hysterectomy. Eligible participants are randomly assigned to either a coffee intervention group receiving standard postoperative care plus coffee at predetermined postoperative time points or a control group receiving standard postoperative care alone. The primary objective is to determine whether postoperative coffee consumption improves bowel recovery and shortens hospitalization.
Detailed description
Laparoscopic hysterectomy is one of the most commonly performed minimally invasive gynecological procedures. Although enhanced recovery after surgery (ERAS) protocols have improved postoperative outcomes, delayed gastrointestinal recovery and postoperative ileus continue to affect patient recovery, comfort, and hospital length of stay.
Coffee contains several bioactive compounds that may stimulate gastrointestinal motility through multiple physiological mechanisms, including increased gastrin secretion, activation of the gastrocolic reflex, and enhanced colonic motor activity. Previous clinical studies have suggested that postoperative coffee consumption may accelerate bowel function recovery after abdominal surgery; however, evidence specific to laparoscopic hysterectomy remains limited.
This single-center, randomized controlled trial evaluates the effectiveness of postoperative coffee consumption in women undergoing laparoscopic hysterectomy. Fifty eligible participants are randomly allocated in a 1:1 ratio to either an intervention group or a control group using block randomization. Participants in the intervention group receive standard postoperative care together with 100 mL of soluble coffee prepared with hot water at postoperative hours 6, 12, and 18, whereas participants in the control group receive standard postoperative care alone.
The study evaluates postoperative bowel recovery by assessing bowel sounds, passage of flatus, passage of stool, abdominal distension, nausea, vomiting, distension-related pain, and length of hospital stay. The findings are expected to provide evidence regarding a simple, low-cost, and feasible nursing intervention that may improve postoperative recovery following laparoscopic hysterectomy.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
- Model description
- Participants were randomly assigned in a 1:1 ratio to either the intervention or control group using block randomization. The intervention group received postoperative coffee in addition to standard postoperative care, whereas the control group received standard postoperative care alone.
| Arm | Type | Receives |
|---|---|---|
| Coffee Group | Experimental | Behavioral: Postoperative Coffee ConsumptionParticipants received standard postoperative care plus 100 mL of soluble coffee prepared with hot water at postoperative 6, 12, and 18 hours. |
| Control Group | No intervention | –Participants received standard postoperative care according to institutional clinical practice without postoperative coffee consumption. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (5 listed)
- Women aged 18 years or older.
- Scheduled for elective laparoscopic hysterectomy.
- Able to consume oral fluids according to the ERAS protocol.
- Able to communicate in Turkish.
- Willing to participate and provide written informed consent.
Key exclusion criteria (5 listed)
- Emergency surgery.
- Known allergy or intolerance to coffee or caffeine.
- Gastrointestinal diseases or conditions affecting bowel motility.
- Postoperative complications requiring intensive care or preventing oral intake.
- Withdrawal of informed consent at any stage of the study.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Postoperative Coffee ConsumptionParticipants received 100 mL of hot soluble coffee prepared with hot water at postoperative hours 6, 12, and 18 in addition to standard postoperative ERAS care. | Behavioural | Coffee Group |
Primary outcome
Time to First Passage of Flatus
Time frame: From the end of surgery until the first passage of flatus, assessed for up to 72 hours after surgery.
Time from the end of surgery to the first passage of flatus, recorded in hours.
3 secondary outcomes
Time to First Defecation
Time frame: From the end of surgery until the first bowel movement, assessed for up to 72 hours after surgery.
Time to First Bowel Sounds
Time frame: From the end of surgery until the first bowel sounds are detected, assessed for up to 72 hours after surgery.
Length of Hospital Stay
Time frame: From the date of surgery until hospital discharge, assessed for up to 5 days after surgery.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 7 Jul 2026.
- Individual participant dataSharing planned: No. Individual participant data (IPD) will not be shared. The study did not include a data-sharing plan, and participant confidentiality will be maintained.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Müzeyyen Ataseven, PhD,RN principal investigator
Istanbul Medipol University, Faculty of Health Sciences
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Postoperative Coffee Consumption in people with Hysterectomy and Gastrointestinal Motility Disorder, run by Istanbul Medipol University Hospital at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 7 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Time to First Passage of Flatus (time frame: From the end of surgery until the first passage of flatus, assessed for up to 72 hours after surgery.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 7 Jul 2026.