Clinical trials: Postoperative Ileus
Postoperative Ileus
Electroacupuncture Combined With Fast-track Perioperative Program for Laparoscopic Colorectal Surgery
Background: The investigators' previous study demonstrated that electroacupuncture (EA) reduces the duration of postoperative ileus and hospital stay after laparoscopic colorectal surgery within a traditional perioperative care…
- Trial name
- NCT04090073
- Testing
- Electroacupuncture, Fast-track Perioperative program
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Chinese University of Hong Kong
Cesarean Section Complications
Outcomes of Early Versus Delayed Oral Feeding After Cesarean Section in Korle-bu Teaching Hospital
study compares the outcomes of feeding mothers early (4 hours ) after cesarean section compared to delayed feeding (on post operation day 1) in terms of gastrointestinal function and maternal satisfaction with the feeding…
- Trial name
- NCT03070795
- Testing
- early feeding, delayed feeding
- Where
- Ghana
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- University of Ghana Medical School
Colon Cancer, Colon Diverticulosis
Multimodal Narcotic Limited Perioperative Pain Control With Colorectal Surgery
The General Objective of this study is to investigate the cost and efficacy of treating patients undergoing colorectal surgical resections with an opioid limited pain control regimen as part of an Enhanced Recovery After Surgery…
- Conditions
- Colon Cancer, Colon Diverticulosis, Colonic Neoplasms, Colonic Diverticulitis
- Trial name
- NCT02958566
- Testing
- Acetaminophen, Gabapentin, Orphenadrine
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Illinois College of Medicine at Peoria
Incarcerated Hernia, Appendicitis Acute
Prevention of Postoperative Hernias in Emergency Surgery
The aim of this observational study is to understand the risk factors and incidence of postoperative hernias among patients undergoing emergency surgery.
- Conditions
- Incarcerated Hernia, Appendicitis Acute, Cholecystitis, Acute, Ileus
- Trial name
- PROPHECY (NCT06815822)
- Where
- Poland
- Volunteers
- 500 people
- Sponsor
- Jan Kochanowski University
Ileus
Intermountain Healthcare's Enhanced Recovery Protocol for Colon Surgery With and Without Alvimopan Use
The purpose of this study is to determine if the addition of alvimopan to our care process model for colon resection patients will decrease length of stay.
- Trial name
- NCT01143259
- Testing
- Alvimopam, 300 mg Polyethylene
- Where
- 9 sites in United States
- Volunteers
- 274 people
- Sponsor
- Intermountain Health Care, Inc.
Pancreas Neoplasm
Effects of Chewing Gum Against Postoperative Ileus
The purpose of this study is to determine whether the use of chewing gum effects postoperative ileus after pancreaticoduodenectomy
- Trial name
- NCT04768660
- Testing
- gum
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Assiut University
Ileus
Study to Evaluate LB1148 for Return of Gastrointestinal Function, Decrease Post-Operative Ileus
The purpose of this study is to establish preliminary evidence of the efficacy, safety, and tolerability of LB1148 for the treatment of return of gastrointestinal function and decrease Post-Operative Ileus in subjects undergoing…
- Trial name
- NCT05056935
- Testing
- LB1148
- Where
- 6 sites in China
- Volunteers
- 131 people
- Sponsor
- Newsoara Biopharma Co., Ltd.
Postoperative Ileus, Colorectal Cancer Control and Prevention
Implementation of an Efferent Loop Stimulation Protocol Prior to Ileostomy Closure at La Paz University Hospital
Stoma creation is a common surgical procedure, employed in certain contexts within general surgery, particularly in colorectal and emergency surgery.
- Conditions
- Postoperative Ileus, Colorectal Cancer Control and Prevention, Stoma - Ileostomy
- Trial name
- NCT06974500
- Testing
- Daily efferent limb stimulation for at least two weeks prior to surgery using saline solution and a thickering agent
- Where
- Spain
- Volunteers
- 68 people
- Sponsor
- Hospital Universitario La Paz
Ileus, Gastrointestinal Dysfunction
Alvimopan as a Rescue Treatment of Postoperative Ileus
This study aims to evaluate the cost effectiveness of Alvimopan as rescue therapy in patients undergoing colorectal or small bowel resection who develop POI, and its safety and effectiveness in reducing LOS and POI duration.
- Trial name
- NCT04405037
- Testing
- Alvimopan
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Scott Steele
Postoperative Ileus
A Study of Alvimopan for the Management of Postoperative Ileus in Participants Undergoing Radical Cystectomy
This study is being conducted to determine whether alvimopan can accelerate recovery of gastrointestinal function following radical cystectomy when compared with a placebo.
- Trial name
- NCT00708201
- Testing
- Alvimopan
- Where
- 20 sites in United States
- Volunteers
- 280 people
- Sponsor
- Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Postoperative Ileus, Surgery-Complications
Intestinal Microbiota and Postoperative Ileus After Colorectal Surgery
Postoperative ileus (POI) after colorectal surgery is frequent and is a burden for national health authority because it increases the morbidity and the length of hospital stay.
- Trial name
- MICRO-IPO (NCT05512741)
- Testing
- Feces collection
- Where
- France
- Volunteers
- 64 people
- Sponsor
- University Hospital, Angers
Bladder Cancer, Cystostomy; Complications
Evaluation of Naloxegol in the Prevention of POI After Cystectomy
Postoperative ileus (POI) is defined as a transient reduction of bowel motility that prevents effective transit of bowel content and tolerance of oral intake following surgical interventions, especially after radical cystectomy.
- Trial name
- ANTAGOCYST (NCT04219046)
- Testing
- Naloxégol oxalate
- Sponsor
- Institut Paoli-Calmettes
Ileus
Study of Alvimopan for the Management of Opioid-induced Postoperative Bowel Dysfunction/Postoperative Ileus
Patients undergoing major abdominal surgery are at highest risk for developing Postoperative Ileus (POI), occurring in nearly all cases.
- Trial name
- NCT00205842
- Testing
- alvimopan
- Where
- United States
- Volunteers
- 660 people
- Sponsor
- Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Ileus, Opioid Use
Postoperative Opioid Use and Ileus Occurrence---A Case Control Study
Postoperative ileus (POI) is a significant complication after colorectal surgery, with reported incidence ranging from 10~30%, leading to increased morbidity, hospital length of stay, and thus medical cost.
- Trial name
- NCT05262569
- Testing
- ileus
- Where
- China
- Volunteers
- 596 people
- Sponsor
- Peking University People's Hospital
Pain, Postoperative, Postoperative Ileus
Effect of Tegileridine on Postoperative Bowel Function Recovery in Abdominal Surgery
Title: Effect of Tegileridine on Postoperative Bowel Function Recovery in Abdominal Surgery: A Multicenter, Randomized, Controlled Trial The goal of this clinical trial is to evaluate the effectiveness and safety of tegileridine…
- Trial name
- NCT07412223
- Testing
- Tegileridine, Morphine
- Where
- 3 sites in China
- Volunteers
- 152 people
- Sponsor
- Xiangya Hospital of Central South University
Post-Operative Ileus (POI)
Study of Intravenous (IV) Methylnaltrexone Bromide (MNTX) in the Treatment of Post-Operative Ileus (POI)
To evaluate the safety and efficacy of MNTX in participants who have undergone segmental colectomy and to assess if the time between the end of surgery and the first bowel movement is significantly shorter in the MNTX regimen…
- Trial name
- NCT00401375
- Testing
- Methylnaltrexone
- Where
- United States
- Volunteers
- 524 people
- Sponsor
- Bausch Health Americas, Inc.
Paralytic Ileus
Daikenchuto for Intestinal Dysmotility and Prevention of Postoperative Paralytic Ielus After Pancreaticoduodenectomy
A multicenter randomized-controlled trial of daikenchuto (TJ-100), a traditional Japanese herbal medicine (Kampo), to investigate its effect on intestinal dysmotility and for the prevention of postoperative paralytic ileus.
- Trial name
- JAPAN-PD (NCT01607307)
- Testing
- Oral/enteral TJ-100 solution
- Where
- 5 sites in Japan
- Volunteers
- 220 people
- Sponsor
- Wakayama Medical University
Ileus
Study of Alvimopan for the Management of Opioid-induced Postoperative Bowel Dysfunction/ Postoperative Ileus
Patients undergoing major abdominal surgery are at highest risk for developing postoperative ileus (POI), occurring in nearly all cases.
- Trial name
- NCT00388479
- Testing
- Alvimopan
- Where
- United States
- Volunteers
- 666 people
- Sponsor
- Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Postoperative Ileus
Effect of Mosapride on Postoperative Ileus in Patients Undergoing Colorectal Surgery
Postoperative Ileus is defined as the transient postoperative functional inhibition of propulsive bowel activity. The ethiology of this process can best be described as multifactorial.
- Trial name
- ILEUS (NCT02056405)
- Testing
- Mosapride
- Where
- Argentina
- Volunteers
- 90 people
- Sponsor
- Hospital Italiano de Buenos Aires
Postoperative Ileus
The Effect of Coffee After Resection of Small Bowel
Post-operative ileus ("post-op ileus") is a condition which can occur after surgery. This means that the bowels stop working correctly and food and liquids will not pass through in the normal manner.
- Trial name
- NCT03143621
- Testing
- Coffee, Water
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Mount Carmel Health System