Thyroid DiseasesNCT07707401
Effectiveness of WeChat-Supported Neck Rehabilitation Exercises on Early Recovery After Thyroidectomy
A study testing WeChat-supported Neck Rehabilitation Exercise and Standardized Postoperative Care and Video Education in people with Thyroid Diseases and Thyroid Cancer, run by Shanghai 6th People's Hospital at 1 site in China.
Trial summary
This study aimed to evaluate the effectiveness, safety, and implementation outcomes of a WeChat mini program-supported tele-neck rehabilitation exercises for improving early postoperative neck recovery after thyroidectomy. Read more about this study
- Who is it for?
- Ages 18 to 60 years
- Conditions the study is for
- Thyroid Diseases, Thyroid Cancer, Surgery
- What is being tested?
- WeChat-supported Neck Rehabilitation Exercise and Standardized Postoperative Care and Video Education
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 200 participants
- Where
- 1 siteChina
- Study dates
- 9 Sep 2026to 30 Jun 2029
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 60 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Undergoing thyroid surgery
- Postoperative condition stable, with the attending physician assessing the patient as fit for neck movement
- Willing to participate in the study, complete scheduled follow-ups, and sign a written informed consent form
Who cannot join
- History of prior thyroid or neck surgery
- History of cervical spondylosis, cervical spine surgery, neck trauma, or other conditions affecting neck mobility
- Postoperative complications rendering the patient unsuitable for neck movement training, such as confirmed recurrent laryngeal nerve injury, chyle leak, or complications requiring reoperation or prolonged drainage, or incision infection
- Persistent postoperative dizziness or other conditions unsuitable for exercise
- Unable to use WeChat and lacking assistance from family members
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
China1 site, 1 recruiting
- Recruiting
Shanghai Sixth People's Hospital
Shanghai, Shanghai Municipality, 200233
Ling Zhan, Doctor, 08615821120972, rebecca0428zhan@163.com
About this study
Official title: Effectiveness of WeChat-Supported Neck Rehabilitation Exercises on Early Recovery After Thyroidectomy: A Randomized Controlled Trial
This study aimed to evaluate the effectiveness, safety, and implementation outcomes of a WeChat mini program-supported tele-neck rehabilitation exercises for improving early postoperative neck recovery after thyroidectomy.
- Conditions
- Thyroid Diseases, Thyroid Cancer, Surgery, Postoperative Pain
- Being tested
- WeChat-supported Neck Rehabilitation Exercise, Standardized Postoperative Care and Video Education
- Keywords
- Tele-exercise program, Telehealth, Health-related quality of life, Postoperative rehabilitation, Thyroidectomy, Neck exercise
- Medical subject headings
- Thyroid Diseases, Thyroid Neoplasms, Pain, Postoperative
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
WeChat-supported Neck Rehabilitation ExerciseBehavioural
WeChat mini program-supported neck exercise management includes daily exercise reminders, exercise check-ins, symptom reporting, automated abnormal symptom prompts, and standardized remote feedback from the research team.
Standardized Postoperative Care and Video EducationBehavioural
This intervention consists of standard clinical postoperative care and discharge education, encompassing wound management, follow-up appointments, and generic neck activity guidelines. Prior to discharge or upon clinical stability, participants undergo a one-time, face-to-face training session with research staff featuring practical exercise demonstrations and behavioral precautions, and are provided with identical instructional video materials for home reference.
| Study group | Role | What they receive |
|---|---|---|
| WeChat-supported tele-rehabilitation group | Experimental | Participants in the WeChat-supported tele-rehabilitation group received WeChat mini program-supported postoperative neck exercise management. Receives: Behavioral: WeChat-supported Neck Rehabilitation Exercise; Behavioral: Standardized Postoperative Care and Video Education |
| Routine care group | Active comparator | Participants in the routine care group did not receive WeChat mini program-supported postoperative neck exercise management. Receives: Behavioral: Standardized Postoperative Care and Video Education |
What is being measured
The primary outcome is the main question the study is designed to answer.
Neck Pain and Disability Scale (NPDS) Score
The NPDS is used to evaluate post-surgical neck pain and its multi-dimensional impact on daily living, emotions, work, and social activities. The total score ranges from 0 to 100, with higher scores representing more severe neck pain and structural functional impairment.
Measured: Preoperative baseline; the day of drainage removal; and 7, 14, and 30 days after drainage removal
Secondary outcomes (4)
Neck Movement Pain Score
Assessment of localized pain severity provoked during active cervical movements, including neck flexion, extension, left/right lateral flexion, and left/right rotation. Each of the six movements is scored categorically as 0 (painless), 1 (mild pain), or 2 (severe pain), yielding a cumulative score range of 0 to 12. Higher total scores indicate more pronounced motion-induced cervical pain.
Measured: Preoperative baseline; the day of drainage removal; and 7, 14, and 30 days after drainage removal
Health-related quality of life
Health-related quality of life will be assessed using the EuroQol 5-Dimension 5-Level questionnaire (EQ-5D-5L). The descriptive system assesses five dimensions: mobility, self-care, usual activities, pain/discomfort, and anxiety/depression, with five response levels for each dimension.
Measured: Preoperative baseline; the day of drainage removal; and 7, 14, and 30 days after drainage removal
Incidence of Surgical Complications and Intervention-Related Adverse Events
Safety endpoints mapping the frequency and severity of post-surgical complications (e.g., wound bleeding/hematoma, incision dehiscence, surgical site infection) or any adverse events deemed by the investigator to be potentially related to the physical exercise regimen (e.g., severe motion-induced pain exacerbation, acute dizziness).
Measured: Up to 3 month post-operation
Cervical Range of Motion (ROM)
Objective clinical measurement of neck mobility, quantifying the exact degrees of cervical movement achieved during forward flexion, backward extension, left/right lateral flexion, and left/right rotation, assessed by a blinded investigator.
Measured: Preoperative baseline; the day of drainage removal; and 7, 14, and 30 days after drainage removal
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted16 Jul 2026
- Study start9 Sep 2026
- Primary completion31 Dec 2028 (estimated)
- Study completion30 Jun 2029 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Thyroid DiseasesStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 200 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Shanghai 6th People's Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Ling Zhan, Shanghai 6th People's Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07707401
- Sponsor's protocol ID
- 2026-KY-277(K)
- Status last verified
- Sep 2026
- First submitted
- 13 Jul 2026
- Last updated
- 10 Sep 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 10 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effectiveness of WeChat-Supported Neck Rehabilitation Exercises on Early Recovery After Thyroidectomy: A Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT07707401
- Acronym / sponsor ID
- 2026-KY-277(K)
- Conditions
- Thyroid Diseases, Thyroid Cancer, Surgery, Postoperative Pain
- Keywords
- Tele-exercise program, Telehealth, Health-related quality of life, Postoperative rehabilitation, Thyroidectomy, Neck exercise
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 200 participants (estimated)
- Lead sponsor
- Shanghai 6th People's HospitalUniversity, hospital or other
- Study start
- 9 Sep 2026 (actual)
- Primary completion
- 31 Dec 2028 (estimated)
- Study completion
- 30 Jun 2029 (estimated)
- First posted
- 16 Jul 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aimed to evaluate the effectiveness, safety, and implementation outcomes of a WeChat mini program-supported tele-neck rehabilitation exercises for improving early postoperative neck recovery after thyroidectomy.
Study design
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| WeChat-supported tele-rehabilitation group | Experimental | Behavioral: WeChat-supported Neck Rehabilitation Exercise, Behavioral: Standardized Postoperative Care and Video EducationParticipants in the WeChat-supported tele-rehabilitation group received WeChat mini program-supported postoperative neck exercise management. |
| Routine care group | Active comparator | Behavioral: Standardized Postoperative Care and Video EducationParticipants in the routine care group did not receive WeChat mini program-supported postoperative neck exercise management. |
Who may qualify
- Ages
- 18 to 60 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (3 listed)
- Undergoing thyroid surgery
- Postoperative condition stable, with the attending physician assessing the patient as fit for neck movement
- Willing to participate in the study, complete scheduled follow-ups, and sign a written informed consent form
Key exclusion criteria (5 listed)
- History of prior thyroid or neck surgery
- History of cervical spondylosis, cervical spine surgery, neck trauma, or other conditions affecting neck mobility
- Postoperative complications rendering the patient unsuitable for neck movement training, such as confirmed recurrent laryngeal nerve injury, chyle leak, or complications requiring reoperation or prolonged drainage, or incision infection
- Persistent postoperative dizziness or other conditions unsuitable for exercise
- Unable to use WeChat and lacking assistance from family members
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| WeChat-supported Neck Rehabilitation ExerciseWeChat mini program-supported neck exercise management includes daily exercise reminders, exercise check-ins, symptom reporting, automated abnormal symptom prompts, and standardized remote feedback from the research team. | Behavioural | WeChat-supported tele-rehabilitation group |
| Standardized Postoperative Care and Video EducationThis intervention consists of standard clinical postoperative care and discharge education, encompassing wound management, follow-up appointments, and generic neck activity guidelines. Prior to discharge or upon clinical stability, participants undergo a one-time, face-to-face training session with research staff featuring practical exercise demonstrations and behavioral precautions, and are provided with identical instructional video materials for home reference. | Behavioural | Routine care group, WeChat-supported tele-rehabilitation group |
Primary outcome
Neck Pain and Disability Scale (NPDS) Score
Time frame: Preoperative baseline; the day of drainage removal; and 7, 14, and 30 days after drainage removal
The NPDS is used to evaluate post-surgical neck pain and its multi-dimensional impact on daily living, emotions, work, and social activities. The total score ranges from 0 to 100, with higher scores representing more severe neck pain and structural functional impairment.
4 secondary outcomes
Neck Movement Pain Score
Time frame: Preoperative baseline; the day of drainage removal; and 7, 14, and 30 days after drainage removal
Health-related quality of life
Time frame: Preoperative baseline; the day of drainage removal; and 7, 14, and 30 days after drainage removal
Incidence of Surgical Complications and Intervention-Related Adverse Events
Time frame: Up to 3 month post-operation
Cervical Range of Motion (ROM)
Time frame: Preoperative baseline; the day of drainage removal; and 7, 14, and 30 days after drainage removal
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 10 Sep 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing WeChat-supported Neck Rehabilitation Exercise and Standardized Postoperative Care and Video Education in people with Thyroid Diseases and Thyroid Cancer, run by Shanghai 6th People's Hospital at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 10 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Ling Zhan, Dr (+8615821120972, rebecca0428zhan@163.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Neck Pain and Disability Scale (NPDS) Score (time frame: Preoperative baseline; the day of drainage removal; and 7, 14, and 30 days after drainage removal). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 10 Sep 2026; AzTrials last refreshed its copy on 8 Nov 2026.