Healthy AdultNCT07711340
Diurnal Strength Variation
A study testing Time-driven dosing in people with Healthy Adult and Exercise, run by Stanford University at 1 site in United States.
Trial summary
Healthy individuals will be tested at different times of day to determine whether exercise at a non-expected time results in poorer performance. Read more about this study
- Who is it for?
- Ages 18 to 25 yearsHealthy volunteers can take part
- Conditions the study is for
- Healthy Adult, Exercise
- What is being tested?
- Time-driven dosing
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 20 participants
- Where
- 1 siteUnited States
- Study dates
- 1 Aug 2026to 31 Dec 2027
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 25 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- Healthy
- 18-25 years old
- Lower body exercise three or more times per week, all at the same time of day (within 2 hour window)
- Regular meal times (±1 hour window)
- Regular sleep times (±1 hour window)
Who cannot join
- Active or uncontrolled mental or physical health issues
- Current musculoskeletal injury
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Exercise Timing and Lower Limb Biomechanics
Healthy individuals will be tested at different times of day to determine whether exercise at a non-expected time results in poorer performance.
- Conditions
- Healthy Adult, Exercise
- Being tested
- Time-driven dosing
- Medical subject headings
- Motor Activity
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Time-driven dosingBehavioural
Three hours earlier or later than usual exercise
| Study group | Role | What they receive |
|---|---|---|
| Regular Exercise | No intervention | Exercise at the usual time |
| Early Exercise | Experimental | Exercise three hours earlier than usual Receives: Behavioral: Time-driven dosing |
| Exercise Late | Experimental | Exercise three hours later than usual Receives: Behavioral: Time-driven dosing |
What is being measured
The primary outcome is the main question the study is designed to answer.
Isometric quadriceps strength
isometric quadriceps strength as determined during dynamometer testing
Measured: 15 minutes
Secondary outcomes (2)
Isometric hamstring strength
Hamstring strength as determined during dynamometer testing
Measured: 15 minutes
Isokinetic hamstring/quad strength
Hamstring/quad strength as determined during dynamometer testing
Measured: 15 minutes
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted17 Jul 2026
- Study start1 Aug 2026
- Primary completion30 Sep 2027 (estimated)
- Study completion31 Dec 2027 (estimated)
Why it stopped: no personnel to current run this study
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Healthy AdultStudies of the same condition, open and under way.
- More trials run by Stanford UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 20 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Stanford University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Jamie Zeitzer, Stanford University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07711340
- Sponsor's protocol ID
- 87320
- Status last verified
- Sep 2026
- First submitted
- 14 Jul 2026
- Last updated
- 28 Sep 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: Deidentified outcome data from muscle testing will be shared on Dryad.
Study at a glance
From the registry record, last updated by the sponsor on 28 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Exercise Timing and Lower Limb Biomechanics
- ClinicalTrials.gov ID
- NCT07711340
- Acronym / sponsor ID
- 87320
- Conditions
- Healthy Adult, Exercise
- Study type
- Interventional
- Recruitment status
- SuspendedReason stopped: no personnel to current run this study
- Enrolment
- 20 participants (estimated)
- Lead sponsor
- Stanford UniversityUniversity, hospital or other
- Study start
- 1 Aug 2026 (actual)
- Primary completion
- 30 Sep 2027 (estimated)
- Study completion
- 31 Dec 2027 (estimated)
- First posted
- 17 Jul 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Healthy individuals will be tested at different times of day to determine whether exercise at a non-expected time results in poorer performance.
Study design
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| Regular Exercise | No intervention | –Exercise at the usual time |
| Early Exercise | Experimental | Behavioral: Time-driven dosingExercise three hours earlier than usual |
| Exercise Late | Experimental | Behavioral: Time-driven dosingExercise three hours later than usual |
Who may qualify
- Ages
- 18 to 25 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (5 listed)
- Healthy
- 18-25 years old
- Lower body exercise three or more times per week, all at the same time of day (within 2 hour window)
- Regular meal times (±1 hour window)
- Regular sleep times (±1 hour window)
Key exclusion criteria (2 listed)
- Active or uncontrolled mental or physical health issues
- Current musculoskeletal injury
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Time-driven dosingThree hours earlier or later than usual exercise | Behavioural | Early Exercise, Exercise Late |
Primary outcome
Isometric quadriceps strength
Time frame: 15 minutes
isometric quadriceps strength as determined during dynamometer testing
2 secondary outcomes
Isometric hamstring strength
Time frame: 15 minutes
Isokinetic hamstring/quad strength
Time frame: 15 minutes
Results and safety
Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 28 Sep 2026.
- Individual participant dataSharing planned: Yes. Deidentified outcome data from muscle testing will be shared on Dryad.
Related trials for Healthy Adult
Not yet recruitingPhase 1
A Study of Phenytoin Mucoadhesive Film for Oral Ulcers in Healthy Volunteers
Oral Ulcer, Oral Mucositis
Active, not recruiting
Deliver-EE: Evaluating Effects of Meal Delivery
Healthy
Not yet recruiting
Healthy Adults Aged 18-55, Three Ukrainian Windlass Tourniquets (SICH, DNIPRO GEN 2, PULS) Compared With CAT Gen 7, and Complete Limb Arterial Occlusion Confirmed by Doppler.
Hemorrhage, Healthy Volunteers
Recruiting
Methylation Analyses for Gynaecological Research Through Home-based Self-sampling
Healthy Adult Participants, Gynecological Disease
Recruiting
Nicotinamide Riboside, Vit B3 Analogue, and Brain Energy Metabolism
Healthy Adult
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Time-driven dosing in people with Healthy Adult and Exercise, run by Stanford University at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: paused, as of the sponsor's last update on 28 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Isometric quadriceps strength (time frame: 15 minutes). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 28 Sep 2026.