Visual LossNCT07715695

Evaluation of a Scalable Educational Intervention for Adjustment and Coping to Vision Loss

A study testing audiovisual educational intervention in people with Visual Loss, run by Brigham and Women's Hospital at 2 sites in United States.

Enrolling by invitation

Enrolling by invitation. The study team selects and invites participants, usually from an existing group of patients.

Sites and contacts

Official record

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Trial summary

The goal of this interventional study is to learn if an educational intervention improves awareness in people experiencing visual loss. The main question it aim to answer is: Will participants have an improved awareness of shared experiences regarding themes such as grief and isolation? Participants will be asked to… Read more about this study

Who is it for?: Ages 18 to 89 years
Conditions the study is for: Visual Loss
What is being tested?: audiovisual educational intervention
Could I receive a placebo?: No, everyone receives an active treatment
How many people: 300 participants
Where: 2 sitesUnited States
Study dates: 21 Jul 2026to 30 Jun 2027
Phase: Interventional
Are there results?: Not yet: the study is under way

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

Ages 18 to 89 years
All sexes
No healthy volunteers
Adult, Older adult

Who may be able to join

have capacity to provide informed consent
have had a visit within a low-vision rehabilitation clinic

Who cannot join

are unable to engage with the audiovisual educational intervention

Trial locations and contacts

2 sites in 1 country. Contact the study team or a site near you to ask about taking part.

United States2 sites

Brigham and Women's Hospital, Mass General Brigham
Boston, Massachusetts, 02115
New England College of Optometry
Boston, Massachusetts, 02115

Other trials in United States

About this study

The goal of this interventional study is to learn if an educational intervention improves awareness in people experiencing visual loss. The main question it aim to answer is:

Will participants have an improved awareness of shared experiences regarding themes such as grief and isolation?

Participants will be asked to answer questions, engage with an audiovisual educational intervention, and then answer additional questions.

Conditions: Visual Loss
Being tested: audiovisual educational intervention
Medical subject headings: Vision Disorders

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

audiovisual educational interventionOther
A brief audiovisual educational intervention.

Study groups in NCT07715695
Study group	Role	What they receive
Educational Intervention Arm	Experimental	Not described Receives: Other: audiovisual educational intervention

What is being measured

The primary outcome is the main question the study is designed to answer.

Change from Baseline in Educational Awareness of Shared Themes as Measured by Likert-scale Questions
Higher values (or increases relative to baseline) correspond to better outcomes, with each question having a minimum value of 1 and a maximum value of 5.
Measured: From baseline to completion of post-intervention questions (e.g., within 1 week).

Secondary outcomes (2)

Change from Baseline in Screening Measures of Depression and Anxiety as Measured by the Patient Health Questionnaire 4 (PHQ-4)
Lower values (or decreases relative to baseline) correspond to better outcomes, with each question having a minimum value of 0 and a maximum value of 3.
Measured: From baseline to completion of post-intervention questions (e.g., within 1 week).
Change from Baseline of Vision-Related Wellbeing as Measured by the Visual Function Questionnaire 25 (VFQ-25) Socioemotional Wellbeing Subscale
Measured: From baseline to completion of post-intervention questions (e.g., within 1 week).

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

21 Jul 202630 Jun 2027

First posted20 Jul 2026
Study start21 Jul 2026
Primary completion30 May 2027 (estimated)
Study completion30 Jun 2027 (estimated)

Resources

Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
Other trials for Visual LossStudies of the same condition, open and under way.
More trials run by Brigham and Women's HospitalThe sponsor's other registered studies.
What the trial phases meanHow a treatment moves from first tests in people to approval.

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design

Study type: Interventional
Phase: Phase N/A
Primary purpose: Other
Allocation: Not applicable
Intervention model: Single group
Masking: None (open label)
Enrolment: 300 participants (estimated)

IDs, dates and publications

ClinicalTrials.gov ID: NCT07715695
Sponsor's protocol ID: 2026P001151
Other IDs: HADLEY-RFA-2026-01
Status last verified: Oct 2026
First submitted: 1 Jul 2026
Last updated: 8 Oct 2026
Results posted: No
Data monitoring committee: No
FDA-regulated drug: No
FDA-regulated device: No
Individual data sharing: No

Interested in taking part?

The sponsor has not listed a contact. The official record may have more details.

Talk to your doctor first and take this page with you. Only the study team can confirm whether you can join.

Questions to ask the study team

What is the study trying to find out?
What would I need to do, and how often would I visit?
Could I receive a placebo instead of the treatment?
What are the possible risks and benefits for me?
Will it cost me anything? Are travel or time paid for?
Can I keep seeing my own doctor during the study?
What happens when the study ends?

See sites and contacts

Recruiting
Brain Stimulation Effects on Orientation and Mobility Skills in Adults With Vision Impairment
Retinitis Pigmentosa (RP), Rod Cone Dystrophy
Active, not recruitingPhase 4
A Study About the Safety of ASP3021 Eye Injections and if They Help People in Japan With Vision Loss From Age-related Macular Degeneration
Geographic Atrophy, Age-Related Macular Degeneration
Not yet recruiting
Multisensory Rehabilitation of Vision Loss After Cortical Damage
Cortical Blindness
Not yet recruiting
Remapping Text in Sentence and Word Tasks to Aid Reading With Central Vision Loss
Macular Degeneration, Central Visual Impairment
RecruitingPhase 1
A Study About the Safety of a Single ASP2020 Eye Injection and if it Helps People With Vision Loss From Stargardt-type Eye Conditions
Stargardt Disease, Stargardt Macular Dystrophy

All Visual Loss trials

Study at a glance

From the registry record, last updated by the sponsor on 8 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.

Official title: Evaluation of a Scalable Educational Intervention for Adjustment and Coping to Vision Loss
ClinicalTrials.gov ID: NCT07715695
Acronym / sponsor ID: 2026P001151
Conditions: Visual Loss
Study type: Interventional
Recruitment status: Enrolling by invitation
Enrolment: 300 participants (estimated)
Lead sponsor: Brigham and Women's HospitalUniversity, hospital or other
Collaborators: New England College of Optometry, Hadley Foundation, Inc.
Study start: 21 Jul 2026 (actual)
Primary completion: 30 May 2027 (estimated)
Study completion: 30 Jun 2027 (estimated)
First posted: 20 Jul 2026 (actual)
Results: Not posted in the source record

Clinical summary

The research question as the sponsor registered it. This describes what the study plans to test, not what it found.

The goal of this interventional study is to learn if an educational intervention improves awareness in people experiencing visual loss. The main question it aim to answer is:

Will participants have an improved awareness of shared experiences regarding themes such as grief and isolation?

Participants will be asked to answer questions, engage with an audiovisual educational intervention, and then answer additional questions.

Study design

Primary purpose: Other
Allocation: Not applicable
Intervention model: Single group
Masking: None (open label)
Number of arms: 1

Arm	Type	Receives
Educational Intervention Arm	Experimental	Other: audiovisual educational intervention

Who may qualify

Ages: 18 to 89 years
Sex: All
Healthy volunteers: Not accepted
Age groups: Adult, Older adult

Key inclusion criteria (2 listed)

have capacity to provide informed consent
have had a visit within a low-vision rehabilitation clinic

Key exclusion criteria (1 listed)

are unable to engage with the audiovisual educational intervention

Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.

Interventions

Intervention	Type	Arms
audiovisual educational interventionA brief audiovisual educational intervention.	Other	Educational Intervention Arm

Primary outcome

Change from Baseline in Educational Awareness of Shared Themes as Measured by Likert-scale Questions
Time frame: From baseline to completion of post-intervention questions (e.g., within 1 week).
Higher values (or increases relative to baseline) correspond to better outcomes, with each question having a minimum value of 1 and a maximum value of 5.

2 secondary outcomes

Change from Baseline in Screening Measures of Depression and Anxiety as Measured by the Patient Health Questionnaire 4 (PHQ-4)
Time frame: From baseline to completion of post-intervention questions (e.g., within 1 week).
Change from Baseline of Vision-Related Wellbeing as Measured by the Visual Function Questionnaire 25 (VFQ-25) Socioemotional Wellbeing Subscale
Time frame: From baseline to completion of post-intervention questions (e.g., within 1 week).

Results and safety

This study is still under way. Results are not available in the source record yet.

Research links

Official record on ClinicalTrials.govLast updated by the sponsor 8 Oct 2026.
Individual participant dataSharing planned: No

Related trials for Visual Loss

Recruiting
Brain Stimulation Effects on Orientation and Mobility Skills in Adults With Vision Impairment
Retinitis Pigmentosa (RP), Rod Cone Dystrophy
Active, not recruitingPhase 4
A Study About the Safety of ASP3021 Eye Injections and if They Help People in Japan With Vision Loss From Age-related Macular Degeneration
Geographic Atrophy, Age-Related Macular Degeneration
Not yet recruiting
Multisensory Rehabilitation of Vision Loss After Cortical Damage
Cortical Blindness
Not yet recruiting
Remapping Text in Sentence and Word Tasks to Aid Reading With Central Vision Loss
Macular Degeneration, Central Visual Impairment
RecruitingPhase 1
A Study About the Safety of a Single ASP2020 Eye Injection and if it Helps People With Vision Loss From Stargardt-type Eye Conditions
Stargardt Disease, Stargardt Macular Dystrophy

Referral and contact

AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.

Ali S Raza, MD, PhD principal investigator

Brigham and Women's Hospital, Mass General Brigham

2 sites in 1 country: see every site and its status.

Questions about this trial

What is this clinical trial studying?

A study testing audiovisual educational intervention in people with Visual Loss, run by Brigham and Women's Hospital at 2 sites in United States.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 2 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: enrolling by invitation, as of the sponsor's last update on 8 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 2 sites in United States. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

This study is still under way. Results are not available in the source record yet.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Change from Baseline in Educational Awareness of Shared Themes as Measured by Likert-scale Questions (time frame: From baseline to completion of post-intervention questions (e.g., within 1 week).). It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT07715695.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 8 Oct 2026.