PericarditisNCT07716696
Effects of Pulmonary Rehabilitation Versus Standard Care in Patients With Pericarditis
A study testing Pulmonary Rehabilitation in people with Pericarditis, run by University of Lahore at 1 site in Pakistan.
Trial summary
Pericarditis is associated with symptoms such as chest pain, dyspnea, fatigue, cough, and anxiety, which can significantly impair functional capacity and quality of life. Pulmonary rehabilitation is a structured intervention designed to improve respiratory function and overall physical performance. Read more about this study
- Who is it for?
- Ages 18 to 65 years
- Conditions the study is for
- Pericarditis
- What is being tested?
- Pulmonary Rehabilitation
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 60 participants
- Where
- 1 sitePakistan
- Study dates
- 11 Dec 2025to 16 Oct 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Diagnosed with pericarditis Age between 18-65 years Both male and female participants Medically stable Able to participate in rehabilitation Willing to provide informed consent
Who cannot join
- Severe cardiovascular or respiratory instability Other major pulmonary diseases Recent surgery or trauma Neurological disorders affecting participation Unwillingness to participate
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Comparative Effects of Pulmonary Rehabilitation Versus Standard Care on Pain, Dyspnea, Cough Severity, Fatigue, and Anxiety in Patients With Pericarditis: A Randomized Controlled Trial
Pericarditis is associated with symptoms such as chest pain, dyspnea, fatigue, cough, and anxiety, which can significantly impair functional capacity and quality of life. Pulmonary rehabilitation is a structured intervention designed to improve respiratory function and overall physical performance. This study aims to compare the effectiveness of pulmonary rehabilitation versus standard care in improving clinical symptoms and functional outcomes in patients with pericarditis.
Read the detailed description
This randomized controlled trial evaluates the comparative effectiveness of pulmonary rehabilitation and standard care in patients diagnosed with pericarditis. Participants are allocated into two groups: an intervention group receiving pulmonary rehabilitation and a control group receiving standard medical care.
Pulmonary rehabilitation includes breathing exercises, aerobic training, and patient education aimed at improving respiratory efficiency and reducing symptom burden. Such programs are widely used to improve functional capacity and quality of life in clinical populations [1].
Outcome measures include pain intensity, dyspnea, cough severity, fatigue, and anxiety, assessed using validated tools such as the Visual Analog Scale (VAS) and McMaster Cough Severity Questionnaire.
Assessments will be conducted at baseline and after completion of the intervention period.
- Conditions
- Pericarditis
- Being tested
- Pulmonary Rehabilitation, Standard Care
- Keywords
- Pulmonary Rehabilitation, Pericarditis, Dyspnea, Chest Pain, Fatigue, Cough, Anxiety
- Medical subject headings
- Pericarditis, Dyspnea, Chest Pain, Fatigue, Cough, Anxiety Disorders
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Pulmonary RehabilitationOther
A structured program including breathing exercises, aerobic conditioning, and patient education administered over multiple weeks.
Standard CareOther
Routine clinical management as prescribed by the treating physician without additional rehabilitation protocol.
| Study group | Role | What they receive |
|---|---|---|
| Pulmonary Rehabilitation Group | Experimental | Participants receive a structured pulmonary rehabilitation program including breathing exercises, aerobic training, and education sessions. Receives: Other: Pulmonary Rehabilitation |
| Standard Care Group | Active comparator | Routine clinical management as prescribed by the treating physician without additional rehabilitation protocol. Receives: Other: Standard Care |
What is being measured
The primary outcome is the main question the study is designed to answer.
Dyspnea Severity
Measured using Visual Analog Scale (VAS)
Measured: Baseline and 8 weeks
Secondary outcomes (4)
Pain Intensity
Measured using VAS
Measured: Baseline and 8 weeks
Cough Severity
Measured using McMaster Cough Severity Questionnaire
Measured: Baseline and 8 weeks
Fatigue
Measured using VAS or standardized fatigue scale
Measured: Time Frame: Baseline and 8 weeks
Anxiety
Measured using a validated anxiety scale
Measured: Time Frame: Baseline and 8 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted21 Jul 2026
- Study start11 Dec 2025
- Primary completion15 Sep 2026 (estimated)
- Study completion16 Oct 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for PericarditisStudies of the same condition, open and under way.
- More trials run by University of LahoreThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Participants are randomly assigned to either pulmonary rehabilitation or standard care groups and followed over the intervention period.
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 60 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of Lahore
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Laiba Ali Khan, University of Lahore
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07716696
- Sponsor's protocol ID
- UOL/IREB/25/15/03/21
- Status last verified
- Jul 2026
- First submitted
- 16 Jul 2026
- Last updated
- 21 Jul 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Individual participant data will not be shared because this study was conducted as an academic research project. The informed consent obtained from participants did not include provisions for public data sharing, and the dataset contains sensitive personal health information. Data will be stored securely and used only for academic and research purposes in accordance with institutional ethics approval.
Study at a glance
From the registry record, last updated by the sponsor on 21 Jul 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparative Effects of Pulmonary Rehabilitation Versus Standard Care on Pain, Dyspnea, Cough Severity, Fatigue, and Anxiety in Patients With Pericarditis: A Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT07716696
- Acronym / sponsor ID
- UOL/IREB/25/15/03/21
- Conditions
- Pericarditis
- Keywords
- Pulmonary Rehabilitation, Pericarditis, Dyspnea, Chest Pain, Fatigue, Cough, Anxiety
- Study type
- Interventional
- Recruitment status
- Active, not recruiting
- Enrolment
- 60 participants (estimated)
- Lead sponsor
- University of LahoreUniversity, hospital or other
- Study start
- 11 Dec 2025 (actual)
- Primary completion
- 15 Sep 2026 (estimated)
- Study completion
- 16 Oct 2026 (estimated)
- First posted
- 21 Jul 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Pericarditis is associated with symptoms such as chest pain, dyspnea, fatigue, cough, and anxiety, which can significantly impair functional capacity and quality of life. Pulmonary rehabilitation is a structured intervention designed to improve respiratory function and overall physical performance. This study aims to compare the effectiveness of pulmonary rehabilitation versus standard care in improving clinical symptoms and functional outcomes in patients with pericarditis.
Detailed description
This randomized controlled trial evaluates the comparative effectiveness of pulmonary rehabilitation and standard care in patients diagnosed with pericarditis. Participants are allocated into two groups: an intervention group receiving pulmonary rehabilitation and a control group receiving standard medical care.
Pulmonary rehabilitation includes breathing exercises, aerobic training, and patient education aimed at improving respiratory efficiency and reducing symptom burden. Such programs are widely used to improve functional capacity and quality of life in clinical populations [1].
Outcome measures include pain intensity, dyspnea, cough severity, fatigue, and anxiety, assessed using validated tools such as the Visual Analog Scale (VAS) and McMaster Cough Severity Questionnaire.
Assessments will be conducted at baseline and after completion of the intervention period.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
- Model description
- Participants are randomly assigned to either pulmonary rehabilitation or standard care groups and followed over the intervention period.
| Arm | Type | Receives |
|---|---|---|
| Pulmonary Rehabilitation Group | Experimental | Other: Pulmonary RehabilitationParticipants receive a structured pulmonary rehabilitation program including breathing exercises, aerobic training, and education sessions. |
| Standard Care Group | Active comparator | Other: Standard CareRoutine clinical management as prescribed by the treating physician without additional rehabilitation protocol. |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (1 listed)
- Diagnosed with pericarditis Age between 18-65 years Both male and female participants Medically stable Able to participate in rehabilitation Willing to provide informed consent
Key exclusion criteria (1 listed)
- Severe cardiovascular or respiratory instability Other major pulmonary diseases Recent surgery or trauma Neurological disorders affecting participation Unwillingness to participate
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Pulmonary RehabilitationA structured program including breathing exercises, aerobic conditioning, and patient education administered over multiple weeks. | Other | Pulmonary Rehabilitation Group |
| Standard CareRoutine clinical management as prescribed by the treating physician without additional rehabilitation protocol. | Other | Standard Care Group |
Primary outcome
Dyspnea Severity
Time frame: Baseline and 8 weeks
Measured using Visual Analog Scale (VAS)
4 secondary outcomes
Pain Intensity
Time frame: Baseline and 8 weeks
Cough Severity
Time frame: Baseline and 8 weeks
Fatigue
Time frame: Time Frame: Baseline and 8 weeks
Anxiety
Time frame: Time Frame: Baseline and 8 weeks
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 21 Jul 2026.
- Individual participant dataSharing planned: No. Individual participant data will not be shared because this study was conducted as an academic research project. The informed consent obtained from participants did not include provisions for public data sharing, and the dataset contains sensitive personal health information. Data will be stored securely and used only for academic and research purposes in accordance with institutional ethics approval.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Pulmonary Rehabilitation in people with Pericarditis, run by University of Lahore at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 21 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Dyspnea Severity (time frame: Baseline and 8 weeks). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 21 Jul 2026.