Clinical trials: Pericarditis
Recurrent Pericarditis
CardiolRx in Recurrent Pericarditis (MAVERIC Phase-3)
Multi-center, randomized, double-blind, placebo-controlled, phase-3 Trial. Patients with a history of recurrent pericarditis who are being treated with an IL-1 blocker for at least 12 months, scheduled to be discontinued, will be…
- Trial name
- MAVERIC (NCT06708299)
- Testing
- CardiolRx
- Where
- 27 sites in United States, Canada and 2 more
- Volunteers
- 110 people
- Sponsor
- Cardiol Therapeutics Inc.
Heart Transplantation, Dilated Cardiomyopathy (DCM)
Multimodal Analysis of Endomyocardial Biopsies
The goal of this observational study is to pursue a multimodal approach to identify the molecular signatures and immune signalling molecules of various myocardial diseases and thereby contribute to improving diagnosis and…
- Conditions
- Heart Transplantation, Dilated Cardiomyopathy (DCM), Hypertrophic Cardiomyopathy (HCM), Myocarditis, Pericarditis
- Trial name
- NCT07359690
- Where
- Germany
- Volunteers
- 216 people
- Sponsor
- University Hospital, Essen
Pericarditis, Pericarditis Acute
Phase 2/3 Study of Participants With Recurrent Pericarditis Evaluating the Efficacy and Safety of KPL-387
This study is being done to demonstrate whether KPL-387 is an effective and safe treatment for recurrent pericarditis.
- Conditions
- Pericarditis, Pericarditis Acute, Recurrent Pericarditis
- Trial name
- PASTORALE (NCT07010159)
- Testing
- KPL-387
- Where
- 66 sites in United States, Canada and 8 more
- Volunteers
- 325 people
- Sponsor
- Kiniksa Pharmaceuticals International, plc
Recurrent Pericarditis
Therapy Management in Patients Treated With Anakinra Due to Recurrent Pericarditis
To determine the utility of serial cardiac magnetic resonance (CMR) imaging for guidance of therapy management in patients treated with anakinra due to recurrent pericarditis (RP), compared with c-reactive protein (CRP) assay…
- Trial name
- NCT06071156
- Testing
- Anakinra
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Azienda Ospedaliero, Universitaria Ospedali Riuniti
Pericarditis, Recurrence
Study of Colchicine to Treat and Prevent Recurrent Pericarditis After Failure of Conventional Treatment.
The purpose of the study is to determine whether colchicine is safe and effective in treatment and prevention of recurrent pericarditis after failure of conventional treatment.
- Trial name
- CORP 2 (NCT00235079)
- Testing
- Colchicine
- Where
- 4 sites in Italy
- Volunteers
- 240 people
- Sponsor
- Azienda Sanitaria Locale 3, Torino
Acute Chest Syndrome
ST Elevation in Acute Chest Pain; Could Measurement of Lipoprotein-associated Phospholipase A2 (Lp-PLA2) be Helpful to the Clinician?
A blood test (2-3 cc peripheral venous blood) drawn /used from already available required lab tests to distinguish between pericarditis accompanied with electrocardiogram (ECG) signs mimicking infarction.
- Trial name
- NCT01041339
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Alexhander Izhaki
Vaccine Adverse Reaction
Genomics and COVID-19 Vaccine Adverse Events
Vaccines routinely used are extremely safe; however, severe adverse events to vaccines do occur. As vaccination against COVID-19 has begun, adverse events to the vaccine, particularly Guillain-Barré syndrome (GBS)…
- Trial name
- NCT05212792
- Testing
- COVID-19 vaccines
- Where
- Canada
- Volunteers
- 6,325 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Recurrent Pericarditis
Impact of CardiolRxTM on Recurrent Pericarditis (MAvERIC-Pilot)
Patients with recurrent pericarditis who are refractory or intolerant to current therapeutic management options or who require long-term administration of corticosteroids to control their disease are particularly challenging to…
- Trial name
- NCT05494788
- Testing
- CardiolRx
- Where
- 8 sites in United States
- Volunteers
- 27 people
- Sponsor
- Cardiol Therapeutics Inc.
Recurrent Pericarditis
REgiStry Of the NAtural History of recurreNt periCarditis in pEdiatric and Adult Patients
The registry will focus on furthering the understanding of the natural history of recurrent pericarditis (RP), as well as document RP-related clinical, health-related quality of life (HRQoL), and economic burden and will assist…
- Trial name
- RESONANCE (NCT04687358)
- Where
- 29 sites in United States
- Volunteers
- 500 people
- Sponsor
- Kiniksa Pharmaceuticals International, plc
Pericarditis, Tako-TSUBO Cardiomyopathy
Inflammatory Disease Biobank for Immunophenotyping and Cardiovascular Research
INFLAME-BANK is a French multicenter prospective observational ancillary study of the international EACVI-INFLAME project. It aims to establish a biobank and perform immunophenotyping and proteomic analyses in patients with…
- Conditions
- Pericarditis, Tako-TSUBO Cardiomyopathy, Myocarditis, Inflammatory Cardiomyopathies
- Trial name
- INFLAME-BANK (NCT07737470)
- Volunteers
- 300 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pericarditis
Effects of Pulmonary Rehabilitation Versus Standard Care in Patients With Pericarditis
Pericarditis is associated with symptoms such as chest pain, dyspnea, fatigue, cough, and anxiety, which can significantly impair functional capacity and quality of life.
- Trial name
- NCT07716696
- Testing
- Pulmonary Rehabilitation, Standard Care
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- University of Lahore
Acute Pericarditis, Pericardial Effusion
Pericardial Fluid Analysis in Recurrent Pericarditis
This clinical trial aims to examine the biochemical and cytological features of pericardial effusion during acute and recurrent pericarditis and to understand the molecular factors responsible for pathogenesis.
- Conditions
- Acute Pericarditis, Pericardial Effusion, Pericardial Disease, Pericardial Fluid Exudate
- Trial name
- PEFLANA (NCT06293924)
- Testing
- Pericardiocentesis, Pericardiotomy, Cytofluorometry and Gene expression analysis
- Where
- Italy
- Volunteers
- 432 people
- Sponsor
- ASST Fatebenefratelli Sacco
Pericarditis
Pericardial Imaging Study
The pericardium is a thin, double-layered sac around the heart that helps reduce friction as the heart moves. When this sac gets inflamed, it is called pericarditis, which can cause serious health problems and even be…
- Trial name
- NCT07245849
- Testing
- 18F-FDG PET/CT
- Volunteers
- 44 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Infective Pericarditis
Improvement of the Etiological Diagnosis of the Pericarditis
Pericardial syndrome includes pericardites acute pericardial effusion and cardiac tamponade, recurrent pericarditis squeezing chronic pericarditis.
- Trial name
- PERICARDITE (NCT02828085)
- Testing
- Nasal swab
- Where
- France
- Volunteers
- 979 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Recurrent Pericarditis
Efficacy and Safety of RPH-104 Treatment in Patients With Recurrent Pericarditis
The primary purpose of this study is the evaluation of the efficacy and safety of RPH-104 treatment in patients with recurrent pericarditis.
- Trial name
- NCT05107934
- Testing
- RPH-104
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- R-Pharm Overseas, Inc.
Idiopathic Recurrent Pericarditis
AnakInRa for Treatment of Recurrent Idiopathic Pericarditis (AIRTRIP)
Recent findings suggest that recurrent pericarditis (RP) may be a previously unrecognized autoinflammatory disease. The pivotal pathogenic role of interleukin (IL)-1 in RP has been shown by the achievement of complete responses…
- Trial name
- AIR TRIP (NCT02219828)
- Testing
- Anakinra
- Where
- 3 sites in Italy
- Volunteers
- 21 people
- Sponsor
- Massimo Imazio
Camptodactyly, Arthropathy
CACP: Study on Camptodactyly - Arthropathy - Coxa Vara - Pericarditis (CACP) Syndrome
CACP syndrome is a rare autosomal recessive disorder characterized by the triad of camptodactyly, non-inflammatory arthropathy with synovial hyperplasia, and coxa vara.
- Conditions
- Camptodactyly, Arthropathy, Coxa Vara, Pericarditis
- Trial name
- CACP (NCT07468461)
- Where
- 10 sites in Italy, Spain and 1 more
- Volunteers
- 15 people
- Sponsor
- Meyer Children's Hospital IRCCS
Postpericardiotomy Syndrome
Study of Colchicine to Prevent the Postpericardiotomy Syndrome
The purpose of the study is to determine whether colchicine is safe and effective in the prevention of the postpericardiotomy syndrome.
- Trial name
- NCT00128427
- Testing
- Colchicine (for 1 month)
- Where
- 6 sites in Italy
- Volunteers
- 360 people
- Sponsor
- Azienda Sanitaria Locale 3, Torino
Diagnostic Self Evaluation
18F-FDG PET/CT in the Diagnosis of Tuberculous Pericarditis
A total of 11 patients confirmed with tuberculous pericarditis were enrolled in this study to analyze the diagnostic value of 18F-FDG PET/CT for tuberculous pericarditis.
- Trial name
- NCT05458089
- Testing
- 18F-FDG
- Volunteers
- 11 people
- Sponsor
- Wuxi No. 4 People's Hospital
Acute Pericarditis
Treatment of Acute Pericarditis With Anakinra
The goal of this study is to determine the safety and efficacy of anakinra for the treatment of acute pericarditis when initiated within 6 hours of diagnosis and continued for 3 or 7 days. 1.
- Trial name
- NCT03224585
- Testing
- Anakinra
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Virginia Commonwealth University