StrokeNCT07725003
Telerehabilitation Based Motor Relearning Program and Telerehabilitation Based Conventional Physical Therapy in Stroke
A study testing Telerehabilitation Based Motor Relearning Program and Conventional physical therapy in people with Stroke, run by Riphah International University at 1 site in Pakistan.
Trial summary
This study aims to compare the effects of telerehabilitation based motor relearning program and telerehabilitation based conventional physical therapy on motor function and balance in stroke patients. Read more about this study
- Who is it for?
- Ages 40 to 70 years
- Conditions the study is for
- Stroke
- What is being tested?
- Telerehabilitation Based Motor Relearning Program and Conventional physical therapy
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 30 participants
- Where
- 1 sitePakistan
- Study dates
- 5 Jun 2025to 6 Aug 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 40 to 70 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Male or female participants.
- Diagnosed with ischemic or hemorrhagic stroke 3-12 months prior to enrollment.
- Medically stable and cleared to participate in physical rehabilitation.
- Mini-Mental State Examination (MMSE) score ≥24.
- Able to understand and follow verbal instructions.
- Have access to a smartphone, tablet, or computer with a stable internet connection for telerehabilitation sessions.
Show all 13Show fewer
- Willing and able to provide written informed consent.
- Exclusion Criteria: MMSE score <24 or severe cognitive impairment.
- Presence of other neurological disorders (e.g., Parkinson's disease or multiple sclerosis).
- Uncontrolled hypertension or recent cardiac event.
- Severe visual, auditory, or communication impairments that prevent participation.
- Currently enrolled in another structured rehabilitation program.
- Any musculoskeletal or medical condition that would interfere with safe participation in the intervention.
Who cannot join
None listed.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Pakistan1 site, 1 recruiting
- Recruiting
Aziz Fatimah Hospital
Faisalabad, Punjab Province, 38000
Misbah Waris, Phd, +92 3008834613, misbah.waris123@gmail.com
khalid.zainab704@gmail.com
About this study
Official title: Comparative Effects of Telerehabilitation Based Motor Relearning Program and Telerehabilitation Based Conventional Physical Therapy on Motor Function and Balance in Stroke Patients.
This study aims to compare the effects of telerehabilitation based motor relearning program and telerehabilitation based conventional physical therapy on motor function and balance in stroke patients.
Read the detailed description
Several recent studies have demonstrated the effectiveness of telerehabilitation in stroke rehabilitation. An umbrella review published in 2024 evaluated systematic reviews and meta-analyses conducted between 2010 and 2023 and concluded that telerehabilitation is effective in enhancing mobility, upper limb function, and balance in post-stroke patients. The review also emphasized the technology's role in increasing access to rehabilitation services and reducing treatment delays, especially in rural or underserved areas. The findings support the integration of telerehabilitation into standard stroke care practices.
A randomized controlled trial conducted in 2023 on 60 post-stroke patients compared home-based telerehabilitation with traditional outpatient therapy over an 8-week period. Participants in both groups demonstrated significant improvements in the Berg Balance Scale (BBS) and Fugl-Meyer Assessment (FMA) scores. However, the telerehabilitation group reported slightly higher patient satisfaction and adherence, indicating that home-based telerehabilitation is a feasible and effective alternative for improving motor function and balance in stroke survivors.
A longitudinal observational study published in 2022 involving 120 individuals in the subacute and chronic phases of stroke recovery explored balance recovery mechanisms. The findings showed that balance impairments are most responsive to intervention within the first six months after stroke, corresponding with a heightened period of neuroplasticity. The study highlighted the importance of early, structured, and task-specific rehabilitation during this critical phase, supporting the potential application of the Motor Relearning Program (MRP).
A pilot study published in 2021 evaluated the feasibility of delivering task-specific therapy through telerehabilitation using video conferencing. The intervention included functional training exercises for 25 stroke patients aged 45-70 years over six weeks. Significant improvements were observed in trunk control, sit-to-stand transfers, and walking ability, with positive participant feedback and no reported adverse events. The findings suggest that telerehabilitation can effectively deliver neurophysiological principles such as motor learning.
A clinical trial conducted in 2020 involving 40 subacute stroke patients assessed the effectiveness of task-specific training based on the Motor Relearning Program (MRP). Participants performed repetitive, goal-oriented functional tasks, including transfers and walking. After four weeks, the intervention group demonstrated significant improvements in trunk control and balance compared with the group receiving standard physiotherapy, indicating that MRP is highly effective in improving motor control and coordination when delivered in person.
A systematic review published in 2020 examined 22 randomized trials investigating telerehabilitation interventions for stroke recovery. The findings indicated that telerehabilitation was non-inferior to conventional in-clinic therapy in improving gait, balance, and upper limb function. The review further emphasized that structured and patient-specific telerehabilitation is particularly beneficial during the subacute stage when recovery potential is highest.
A controlled trial published in 2017 assessed the effectiveness of telerehabilitation in improving motor function after stroke. Fifty stroke patients aged 40-70 years were randomly assigned to either a telerehabilitation group or a conventional therapy group. After eight weeks, both groups showed significant improvements in motor function, while the telerehabilitation group achieved superior balance outcomes, demonstrating the effectiveness of remotely delivered motor-focused interventions.
A foundational publication in 2015 described the theoretical framework of the Motor Relearning Program (MRP). The program emphasizes active participation, task analysis, and repetitive practice to retrain functional movements. Based on principles of motor control and neuroplasticity, MRP is considered particularly effective for post-stroke patients during the recovery period of 3-12 months. Although widely accepted for face-to-face rehabilitation, its application through digital platforms remains underexplored.
Another meta-analysis published in 2015 evaluated telerehabilitation programs for stroke patients and concluded that while telerehabilitation improves overall function, many interventions lacked specificity and did not incorporate evidence-based motor learning principles. The findings highlighted the need to strengthen telerehabilitation frameworks through structured approaches such as the Motor Relearning Program.
Despite the increasing adoption of telerehabilitation in post-stroke care, notable gaps remain in the current body of research. No study to date has directly compared conventional telerehabilitation programs, which are typically based on general physiotherapy principles, with telerehabilitation approaches specifically structured around the Motor Relearning Program. While existing evidence supports the use of general telerehabilitation in improving motor function, balance, and participation among stroke survivors, these programs often lack the task-specific, neuroplasticity-driven framework that defines the Motor Relearning Program. Separately, MRP-based interventions delivered in clinical settings have demonstrated superior outcomes in balance, functional mobility, and motor recovery compared to routine therapy. However, a head-to-head comparison between conventional telerehabilitation and MRP-based telerehabilitation has not yet been explored in published literature. Furthermore, most existing studies are limited by small, homogenous sample sizes, non-standardized outcome measures, and the absence of long-term follow-up. The integration of advanced technologies such as wearable sensors and real-time feedback into telerehabilitation protocols also remains underdeveloped. These gaps highlight the urgent need for rigorous, comparative, and technology-integrated research to evaluate the effectiveness of structured, MRP-based telerehabilitation in diverse stroke populations.
- Conditions
- Stroke
- Being tested
- Telerehabilitation Based Motor Relearning Program, Conventional physical therapy
- Keywords
- Balance Disorders, Motor Relearning Program, Stroke Telerehabilitation
- Medical subject headings
- Stroke
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Telerehabilitation Based Motor Relearning ProgramOther
Also called MRP, Tas-Specific Motor Relearning, Telerehabilitation MRP
Participants will receive a Motor Relearning Program (MRP) delivered through secure video conferencing under the supervision of a physiotherapist. The intervention will be provided 3 sessions per week for 6 weeks (18 sessions total). Each session will last 45-60 minutes, including a warm-up, task-specific functional training, and cool-down. Exercises include sitting and standing balance training, trunk control, sit-to-stand practice, upper limb reaching, trunk rotation, weight-shifting, step training, walking practice, stair simulation, obstacle negotiation, dual-task activities, community mobility simulation, and functional transfer training. Exercise intensity will be moderate and progressively increased according to the participant's tolerance and functional performance.
Conventional physical therapyOther
Also called Standard physical therapy
Participants will receive conventional physiotherapy through secure video conferencing under the supervision of a physiotherapist. The intervention will be provided 3 sessions per week for 6 weeks (18 sessions total). Each session will last 45-60 minutes, including a warm-up, exercise session, and cool-down. The program consists of active-assisted and active range-of-motion exercises, stretching, breathing exercises, strengthening exercises, weight-shifting activities, marching in place, gait training, dynamic mobility exercises, and light resistance exercises using Theraband where appropriate. Exercise intensity will be moderate and adjusted according to each participant's tolerance and clinical progress.
| Study group | Role | What they receive |
|---|---|---|
| Telerehabilitation-Based Motor Relearning Program (MRP) | Experimental | Participants in this arm will receive a structured Motor Relearning Program delivered through telerehabilitation via secure video conferencing. The intervention will consist of task-specific, goal-oriented exercises focusing on trunk control, balance, functional transfers, gait training, and coordination. Sessions will be conducted three times per week for six weeks, with each session lasting 45-60 minutes under the remote supervision of a physiotherapist. Receives: Other: Telerehabilitation Based Motor Relearning Program |
| Telerehabilitation-Based Conventional Physical Therapy | Experimental | Participants in this arm will receive conventional physical therapy delivered through telerehabilitation via secure video conferencing. The intervention will include range-of-motion exercises, stretching, strengthening, balance training, gait exercises, and functional mobility activities. Sessions will be conducted three times per week for six weeks, with each session lasting 45-60 minutes under the remote supervision of a physiotherapist. Receives: Other: Conventional physical therapy |
What is being measured
The primary outcome is the main question the study is designed to answer.
Fugl-Meyer Assessment (FMA) Motor Function Score
Change in motor function will be assessed using the Fugl-Meyer Assessment (FMA). The FMA evaluates motor recovery of the upper and lower extremities, with higher scores indicating better motor function.
Measured: Baseline and after 6 weeks of intervention
Berg Balance Scale (BBS) Score
Balance performance will be assessed using the Berg Balance Scale (BBS). The scale consists of 14 functional balance tasks, with higher scores indicating better balance.
Measured: Baseline and after 6 weeks of intervention
Secondary outcomes (1)
Timed Up and Go (TUG) Test
Functional mobility will be assessed using the Timed Up and Go (TUG) Test by measuring the time required for a participant to stand up from a chair, walk 3 meters, turn, return, and sit down. Lower completion times indicate better functional mobility.
Measured: Baseline and after 6 weeks of intervention
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted24 Jul 2026
- Study start5 Jun 2025
- Primary completion6 Aug 2026 (estimated)
- Study completion6 Aug 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (8)Papers the sponsor has linked to this study.
- Other trials for StrokeStudies of the same condition, open and under way.
- More trials run by Riphah International UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Participant, Investigator
- Enrolment
- 30 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Riphah International University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Misbah Waris, phd, Principal investigator, Riphah International University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07725003
- Sponsor's protocol ID
- REC/RCR & AHS/25/0201
- Status last verified
- Jul 2026
- First submitted
- 21 Jul 2026
- Last updated
- 24 Jul 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Winstein CJ, Stein J, Arena R, Bates B, Cherney LR, Cramer SC, Deruyter F, Eng JJ, Fisher B, Harvey RL, Lang CE, MacKay-Lyons M, Ottenbacher KJ, Pugh S, Reeves MJ, Richards LG, Stiers W, Zorowitz RD; American Heart Association Stroke Council, Council on Cardiovascular and Stroke Nursing, Council on Clinical Cardiology, and Council on Quality of Care and Outcomes Research. Guidelines for Adult Stroke Rehabilitation and Recovery: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association. Stroke. 2016 Jun;47(6):e98-e169. doi: 10.1161/STR.0000000000000098. Epub 2016 May 4.
PubMed 27145936Ghrouz A, Marco E, Munoz-Redondo E, Boza R, Ramirez-Fuentes C, Duarte E. The effect of motor relearning on balance, mobility and performance of activities of daily living among post-stroke patients: Study protocol for a randomised controlled trial. Eur Stroke J. 2022 Mar;7(1):76-84. doi: 10.1177/23969873211061027. Epub 2022 Feb 11.
PubMed 35300258Khallaf ME. Effect of Task-Specific Training on Trunk Control and Balance in Patients with Subacute Stroke. Neurol Res Int. 2020 Nov 17;2020:5090193. doi: 10.1155/2020/5090193. eCollection 2020.
PubMed 33294224Chen J, Jin W, Zhang XX, Xu W, Liu XN, Ren CC. Telerehabilitation Approaches for Stroke Patients: Systematic Review and Meta-analysis of Randomized Controlled Trials. J Stroke Cerebrovasc Dis. 2015 Dec;24(12):2660-8. doi: 10.1016/j.jstrokecerebrovasdis.2015.09.014. Epub 2015 Oct 23.
PubMed 26483155Cramer SC, Dodakian L, Le V, See J, Augsburger R, McKenzie A, Zhou RJ, Chiu NL, Heckhausen J, Cassidy JM, Scacchi W, Smith MT, Barrett AM, Knutson J, Edwards D, Putrino D, Agrawal K, Ngo K, Roth EJ, Tirschwell DL, Woodbury ML, Zafonte R, Zhao W, Spilker J, Wolf SL, Broderick JP, Janis S; National Institutes of Health StrokeNet Telerehab Investigators. Efficacy of Home-Based Telerehabilitation vs In-Clinic Therapy for Adults After Stroke: A Randomized Clinical Trial. JAMA Neurol. 2019 Sep 1;76(9):1079-1087. doi: 10.1001/jamaneurol.2019.1604.
PubMed 31233135Laver KE, Adey-Wakeling Z, Crotty M, Lannin NA, George S, Sherrington C. Telerehabilitation services for stroke. Cochrane Database Syst Rev. 2020 Jan 31;1(1):CD010255. doi: 10.1002/14651858.CD010255.pub3.
PubMed 32002991Alwadai B, Lazem H, Almoajil H, Hall AJ, Mansoubi M, Dawes H. Telerehabilitation and Its Impact Following Stroke: An Umbrella Review of Systematic Reviews. J Clin Med. 2024 Dec 26;14(1):50. doi: 10.3390/jcm14010050.
PubMed 39797132Feigin VL, Brainin M, Norrving B, Martins S, Sacco RL, Hacke W, Fisher M, Pandian J, Lindsay P. World Stroke Organization (WSO): Global Stroke Fact Sheet 2022. Int J Stroke. 2022 Jan;17(1):18-29. doi: 10.1177/17474930211065917.
PubMed 34986727
Study at a glance
From the registry record, last updated by the sponsor on 24 Jul 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparative Effects of Telerehabilitation Based Motor Relearning Program and Telerehabilitation Based Conventional Physical Therapy on Motor Function and Balance in Stroke Patients.
- ClinicalTrials.gov ID
- NCT07725003
- Acronym / sponsor ID
- REC/RCR & AHS/25/0201
- Conditions
- Stroke
- Keywords
- Balance Disorders, Motor Relearning Program, Stroke Telerehabilitation
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 30 participants (estimated)
- Lead sponsor
- Riphah International UniversityUniversity, hospital or other
- Study start
- 5 Jun 2025 (actual)
- Primary completion
- 6 Aug 2026 (estimated)
- Study completion
- 6 Aug 2026 (estimated)
- First posted
- 24 Jul 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aims to compare the effects of telerehabilitation based motor relearning program and telerehabilitation based conventional physical therapy on motor function and balance in stroke patients.
Detailed description
Several recent studies have demonstrated the effectiveness of telerehabilitation in stroke rehabilitation. An umbrella review published in 2024 evaluated systematic reviews and meta-analyses conducted between 2010 and 2023 and concluded that telerehabilitation is effective in enhancing mobility, upper limb function, and balance in post-stroke patients. The review also emphasized the technology's role in increasing access to rehabilitation services and reducing treatment delays, especially in rural or underserved areas. The findings support the integration of telerehabilitation into standard stroke care practices.
A randomized controlled trial conducted in 2023 on 60 post-stroke patients compared home-based telerehabilitation with traditional outpatient therapy over an 8-week period. Participants in both groups demonstrated significant improvements in the Berg Balance Scale (BBS) and Fugl-Meyer Assessment (FMA) scores. However, the telerehabilitation group reported slightly higher patient satisfaction and adherence, indicating that home-based telerehabilitation is a feasible and effective alternative for improving motor function and balance in stroke survivors.
A longitudinal observational study published in 2022 involving 120 individuals in the subacute and chronic phases of stroke recovery explored balance recovery mechanisms. The findings showed that balance impairments are most responsive to intervention within the first six months after stroke, corresponding with a heightened period of neuroplasticity. The study highlighted the importance of early, structured, and task-specific rehabilitation during this critical phase, supporting the potential application of the Motor Relearning Program (MRP).
A pilot study published in 2021 evaluated the feasibility of delivering task-specific therapy through telerehabilitation using video conferencing. The intervention included functional training exercises for 25 stroke patients aged 45-70 years over six weeks. Significant improvements were observed in trunk control, sit-to-stand transfers, and walking ability, with positive participant feedback and no reported adverse events. The findings suggest that telerehabilitation can effectively deliver neurophysiological principles such as motor learning.
A clinical trial conducted in 2020 involving 40 subacute stroke patients assessed the effectiveness of task-specific training based on the Motor Relearning Program (MRP). Participants performed repetitive, goal-oriented functional tasks, including transfers and walking. After four weeks, the intervention group demonstrated significant improvements in trunk control and balance compared with the group receiving standard physiotherapy, indicating that MRP is highly effective in improving motor control and coordination when delivered in person.
A systematic review published in 2020 examined 22 randomized trials investigating telerehabilitation interventions for stroke recovery. The findings indicated that telerehabilitation was non-inferior to conventional in-clinic therapy in improving gait, balance, and upper limb function. The review further emphasized that structured and patient-specific telerehabilitation is particularly beneficial during the subacute stage when recovery potential is highest.
A controlled trial published in 2017 assessed the effectiveness of telerehabilitation in improving motor function after stroke. Fifty stroke patients aged 40-70 years were randomly assigned to either a telerehabilitation group or a conventional therapy group. After eight weeks, both groups showed significant improvements in motor function, while the telerehabilitation group achieved superior balance outcomes, demonstrating the effectiveness of remotely delivered motor-focused interventions.
A foundational publication in 2015 described the theoretical framework of the Motor Relearning Program (MRP). The program emphasizes active participation, task analysis, and repetitive practice to retrain functional movements. Based on principles of motor control and neuroplasticity, MRP is considered particularly effective for post-stroke patients during the recovery period of 3-12 months. Although widely accepted for face-to-face rehabilitation, its application through digital platforms remains underexplored.
Another meta-analysis published in 2015 evaluated telerehabilitation programs for stroke patients and concluded that while telerehabilitation improves overall function, many interventions lacked specificity and did not incorporate evidence-based motor learning principles. The findings highlighted the need to strengthen telerehabilitation frameworks through structured approaches such as the Motor Relearning Program.
Despite the increasing adoption of telerehabilitation in post-stroke care, notable gaps remain in the current body of research. No study to date has directly compared conventional telerehabilitation programs, which are typically based on general physiotherapy principles, with telerehabilitation approaches specifically structured around the Motor Relearning Program. While existing evidence supports the use of general telerehabilitation in improving motor function, balance, and participation among stroke survivors, these programs often lack the task-specific, neuroplasticity-driven framework that defines the Motor Relearning Program. Separately, MRP-based interventions delivered in clinical settings have demonstrated superior outcomes in balance, functional mobility, and motor recovery compared to routine therapy. However, a head-to-head comparison between conventional telerehabilitation and MRP-based telerehabilitation has not yet been explored in published literature. Furthermore, most existing studies are limited by small, homogenous sample sizes, non-standardized outcome measures, and the absence of long-term follow-up. The integration of advanced technologies such as wearable sensors and real-time feedback into telerehabilitation protocols also remains underdeveloped. These gaps highlight the urgent need for rigorous, comparative, and technology-integrated research to evaluate the effectiveness of structured, MRP-based telerehabilitation in diverse stroke populations.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, investigator)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Telerehabilitation-Based Motor Relearning Program (MRP) | Experimental | Other: Telerehabilitation Based Motor Relearning ProgramParticipants in this arm will receive a structured Motor Relearning Program delivered through telerehabilitation via secure video conferencing. The intervention will consist of task-specific, goal-oriented exercises focusing on trunk control, balance, functional transfers, gait training, and coordination. Sessions will be conducted three times per week for six weeks, with each session lasting 45-60 minutes under the remote supervision of a physiotherapist. |
| Telerehabilitation-Based Conventional Physical Therapy | Experimental | Other: Conventional physical therapyParticipants in this arm will receive conventional physical therapy delivered through telerehabilitation via secure video conferencing. The intervention will include range-of-motion exercises, stretching, strengthening, balance training, gait exercises, and functional mobility activities. Sessions will be conducted three times per week for six weeks, with each session lasting 45-60 minutes under the remote supervision of a physiotherapist. |
Who may qualify
- Ages
- 40 to 70 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (13 listed)
- Male or female participants.
- Diagnosed with ischemic or hemorrhagic stroke 3-12 months prior to enrollment.
- Medically stable and cleared to participate in physical rehabilitation.
- Mini-Mental State Examination (MMSE) score ≥24.
- Able to understand and follow verbal instructions.
Key exclusion criteria (0 listed)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Telerehabilitation Based Motor Relearning ProgramAlso: MRP, Tas-Specific Motor Relearning, Telerehabilitation MRPParticipants will receive a Motor Relearning Program (MRP) delivered through secure video conferencing under the supervision of a physiotherapist. The intervention will be provided 3 sessions per week for 6 weeks (18 sessions total). Each session will last 45-60 minutes, including a warm-up, task-specific functional training, and cool-down. Exercises include sitting and standing balance training, trunk control, sit-to-stand practice, upper limb reaching, trunk rotation, weight-shifting, step training, walking practice, stair simulation, obstacle negotiation, dual-task activities, community mobility simulation, and functional transfer training. Exercise intensity will be moderate and progressively increased according to the participant's tolerance and functional performance. | Other | Telerehabilitation-Based Motor Relearning Program (MRP) |
| Conventional physical therapyAlso: Standard physical therapyParticipants will receive conventional physiotherapy through secure video conferencing under the supervision of a physiotherapist. The intervention will be provided 3 sessions per week for 6 weeks (18 sessions total). Each session will last 45-60 minutes, including a warm-up, exercise session, and cool-down. The program consists of active-assisted and active range-of-motion exercises, stretching, breathing exercises, strengthening exercises, weight-shifting activities, marching in place, gait training, dynamic mobility exercises, and light resistance exercises using Theraband where appropriate. Exercise intensity will be moderate and adjusted according to each participant's tolerance and clinical progress. | Other | Telerehabilitation-Based Conventional Physical Therapy |
Primary outcome
Fugl-Meyer Assessment (FMA) Motor Function Score
Time frame: Baseline and after 6 weeks of intervention
Change in motor function will be assessed using the Fugl-Meyer Assessment (FMA). The FMA evaluates motor recovery of the upper and lower extremities, with higher scores indicating better motor function.
Berg Balance Scale (BBS) Score
Time frame: Baseline and after 6 weeks of intervention
Balance performance will be assessed using the Berg Balance Scale (BBS). The scale consists of 14 functional balance tasks, with higher scores indicating better balance.
1 secondary outcome
Timed Up and Go (TUG) Test
Time frame: Baseline and after 6 weeks of intervention
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 24 Jul 2026.
- Background: PubMed 27145936Winstein CJ, Stein J, Arena R, Bates B, Cherney LR, Cramer SC, Deruyter F, Eng JJ, Fisher B, Harvey RL, Lang CE, MacKay-Lyons M, Ottenbacher KJ, Pugh S, Reeves MJ, Richards LG, Stiers W, Zorowitz RD; American Heart Association Stroke Council, Council on Cardiovascular and Stroke Nursing, Council on Clinical Cardiology, and Council on Quality of Care and Outcomes Research. Guidelines for Adult Stroke Rehabilitation and Recovery: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association. Stroke. 2016 Jun;47(6):e98-e169. doi: 10.1161/STR.0000000000000098. Epub 2016 May 4.
- Background: PubMed 35300258Ghrouz A, Marco E, Munoz-Redondo E, Boza R, Ramirez-Fuentes C, Duarte E. The effect of motor relearning on balance, mobility and performance of activities of daily living among post-stroke patients: Study protocol for a randomised controlled trial. Eur Stroke J. 2022 Mar;7(1):76-84. doi: 10.1177/23969873211061027. Epub 2022 Feb 11.
- Background: PubMed 33294224Khallaf ME. Effect of Task-Specific Training on Trunk Control and Balance in Patients with Subacute Stroke. Neurol Res Int. 2020 Nov 17;2020:5090193. doi: 10.1155/2020/5090193. eCollection 2020.
- Background: PubMed 26483155Chen J, Jin W, Zhang XX, Xu W, Liu XN, Ren CC. Telerehabilitation Approaches for Stroke Patients: Systematic Review and Meta-analysis of Randomized Controlled Trials. J Stroke Cerebrovasc Dis. 2015 Dec;24(12):2660-8. doi: 10.1016/j.jstrokecerebrovasdis.2015.09.014. Epub 2015 Oct 23.
- Background: PubMed 31233135Cramer SC, Dodakian L, Le V, See J, Augsburger R, McKenzie A, Zhou RJ, Chiu NL, Heckhausen J, Cassidy JM, Scacchi W, Smith MT, Barrett AM, Knutson J, Edwards D, Putrino D, Agrawal K, Ngo K, Roth EJ, Tirschwell DL, Woodbury ML, Zafonte R, Zhao W, Spilker J, Wolf SL, Broderick JP, Janis S; National Institutes of Health StrokeNet Telerehab Investigators. Efficacy of Home-Based Telerehabilitation vs In-Clinic Therapy for Adults After Stroke: A Randomized Clinical Trial. JAMA Neurol. 2019 Sep 1;76(9):1079-1087. doi: 10.1001/jamaneurol.2019.1604.
- Background: PubMed 32002991Laver KE, Adey-Wakeling Z, Crotty M, Lannin NA, George S, Sherrington C. Telerehabilitation services for stroke. Cochrane Database Syst Rev. 2020 Jan 31;1(1):CD010255. doi: 10.1002/14651858.CD010255.pub3.
- Background: PubMed 39797132Alwadai B, Lazem H, Almoajil H, Hall AJ, Mansoubi M, Dawes H. Telerehabilitation and Its Impact Following Stroke: An Umbrella Review of Systematic Reviews. J Clin Med. 2024 Dec 26;14(1):50. doi: 10.3390/jcm14010050.
- Background: PubMed 34986727Feigin VL, Brainin M, Norrving B, Martins S, Sacco RL, Hacke W, Fisher M, Pandian J, Lindsay P. World Stroke Organization (WSO): Global Stroke Fact Sheet 2022. Int J Stroke. 2022 Jan;17(1):18-29. doi: 10.1177/17474930211065917.
- Individual participant dataSharing planned: No
Related trials for Stroke
Active, not recruitingObservational study
Symptomatic Carotid Outcomes Registry
Carotid Stenosis, Ischemic Stroke
RecruitingPhase 3
Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation
Atrial Fibrillation (AF)
Not yet recruiting
The Effects of an Augmented Reality-Based Mirror Therapy System in Patients With Stroke
Stroke
Recruiting
A Pivotal Study Evaluating Safety and Effectiveness of Adaptative Tip Catheter in Patients With Acute Ischemic Stroke
Ischemic Stroke
RecruitingObservational study
Role of EEG in Differentiation Between Ischemic and Hemorrhagic Stroke
Acute Ischemic Stroke, Acute Haemorrhagic Stroke
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Misbah Waris, phd principal investigator
Riphah International University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Telerehabilitation Based Motor Relearning Program and Conventional physical therapy in people with Stroke, run by Riphah International University at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 13 inclusion and 0 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 24 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Imran Amjad, phd (+923324390125, imran.amjad@riphah.edu.pk), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Fugl-Meyer Assessment (FMA) Motor Function Score (time frame: Baseline and after 6 weeks of intervention). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07725003, which also lists 8 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 24 Jul 2026.