Dental CariesNCT07725757
Caries of First Permanent Molars and Association With Dietary and Oral Habits Among a Group of Egyptian Children
An observational study of Dental Caries, run by October University for Modern Sciences and Arts.
Trial summary
This cross-sectional study aims to assess the prevalence of dental caries in the first permanent molars of Egyptian children aged 6 to 7 years, and to examine how this caries status relates to the children's dietary habits and oral hygiene practices. Read more about this study
- Who is it for?
- Ages 6 to 7 yearsHealthy volunteers can take part
- Conditions the study is for
- Dental Caries
- How many people
- 272 participants
- Where
- No sites listed yet
- Study dates
- 1 Sep 2026to 1 Nov 2026
- How long will I take part?
- 1 Day
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 6 to 7 years
- All sexes
- Healthy volunteers accepted
- Child
Study population: children Aged 6-7 years presented to the Paediatric Dentistry Department, Faculty of Dentistry, October University for Modern Sciences and Arts, and nurses residing in Giza City.
Who may be able to join
- Age: 6 to 7 years old children
- Children with written informed consent from their parents or guardians were included
- Healthy child
Who cannot join
- Previous history/current radiotherapy and/or chemotherapy.
- Presence of retained primary teeth or congenital or developmental anomalies affecting the permanent dentition.
- Missing teeth due to causes other than dental caries.
- Subjects undergoing orthodontic therapy, which might preclude normal tooth brushing.
- Subjects who, in the opinion of the Investigator, may be non-compliant with study procedures.
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
About this study
Official title: Caries Status of First Permanent Molars and Their Association With Dietary and Oral Hygiene Habits Among a Group of Egyptian Children Aged 6-7 Years : A Cross Sectional Study.
This cross-sectional study aims to assess the prevalence of dental caries in the first permanent molars of Egyptian children aged 6 to 7 years, and to examine how this caries status relates to the children's dietary habits and oral hygiene practices. A total of 272 children will undergo a clinical oral examination, and their parents or guardians will complete a structured questionnaire covering diet, tooth-brushing habits, and socio-demographic background. The findings are intended to help identify risk factors associated with early caries in these key teeth, supporting better-targeted preventive dental care for this age group.
Read the detailed description
First permanent molars are the earliest-erupting permanent teeth and, because they emerge without replacing a primary tooth, they are particularly susceptible to plaque accumulation and early carious lesions. As they account for a large proportion of dental caries in school-aged children, their eruption period represents a critical window for preventive interventions such as pit-and-fissure sealants.
Dental caries remains one of the most prevalent chronic diseases in childhood worldwide, with a multifactorial etiology involving diet, sugar consumption, salivary factors, fluoride exposure, and oral hygiene behavior. In Egypt, population-level data on the caries status of first permanent molars specifically - as opposed to caries in the dentition generally - remain limited.
This study will use a cross-sectional observational design conducted in the Paediatric Dentistry Department at October University for Modern Sciences and Arts (Giza, Egypt). Children aged 6-7 years who meet the eligibility criteria (healthy, no history of radiotherapy/chemotherapy, no retained primary teeth or developmental anomalies affecting the permanent dentition, no orthodontic treatment, and provision of parental informed consent) will be enrolled.
Each participating child will receive an intraoral clinical examination using a mirror and CPI probe, following WHO Oral Health Survey (2013) criteria, to assess caries status of the first permanent molars using the DMFT index and to record eruption pattern. Parents/guardians will complete a pre-tested, structured questionnaire (translated into Arabic) capturing dietary habits, tooth-brushing frequency, flossing, sweets intake, dental check-up frequency, fluoride toothpaste use, and socio-demographic variables (child's sex, number of children in the family, parental education).
Based on a previously reported FPM caries prevalence of 5.5%, a sample size of 272 children was calculated (97% confidence interval, 3% margin of error, with finite population correction, using Epi Info v7.2.5.0)
- Conditions
- Dental Caries
- Keywords
- Dental caries, First Permanent Molars, Prevalence, Cross sectional, dietary habits, Oral hygiene habits, Egyptian children
- Medical subject headings
- Dental Caries, Feeding Behavior
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Arm A: children aged 6-7 years | healthy children aged 6 to 7 years old to examine their first permanent molars |
What is being measured
The primary outcome is the main question the study is designed to answer.
DMFT
Measuring DMFT index for first permanent molars
Measured: baseline
Secondary outcomes (3)
DMFS
Measuring DMFS index for first permanent molar
Measured: baseline
Oral hygiene habits
Assessing oral hygiene habits through questionnaire for children aged 6-7 years
Measured: baseline
Dietary habits
Measuring Dietary habits through questionnaire for children aged 6-7 years
Measured: baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted24 Jul 2026
- Study start1 Sep 2026 (estimated)
- Primary completion1 Oct 2026 (estimated)
- Study completion1 Nov 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Dental CariesStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Cross-sectional
- Enrolment
- 272 participants (estimated)
- Target duration
- 1 Day
Sponsor and investigators
- Lead sponsor
- October University for Modern Sciences and Arts
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Nour Mohamed, October University for Modern Sciences and Arts
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07725757
- Sponsor's protocol ID
- MSA Noor
- Status last verified
- Jul 2026
- First submitted
- 21 Jul 2026
- Last updated
- 24 Jul 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 24 Jul 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Caries Status of First Permanent Molars and Their Association With Dietary and Oral Hygiene Habits Among a Group of Egyptian Children Aged 6-7 Years : A Cross Sectional Study.
- ClinicalTrials.gov ID
- NCT07725757
- Acronym / sponsor ID
- MSA Noor
- Conditions
- Dental Caries
- Keywords
- Dental caries, First Permanent Molars, Prevalence, Cross sectional, dietary habits, Oral hygiene habits, Egyptian children
- Study type
- Observational
- Recruitment status
- Not yet recruiting
- Enrolment
- 272 participants (estimated)
- Lead sponsor
- October University for Modern Sciences and ArtsUniversity, hospital or other
- Study start
- 1 Sep 2026 (estimated)
- Primary completion
- 1 Oct 2026 (estimated)
- Study completion
- 1 Nov 2026 (estimated)
- First posted
- 24 Jul 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This cross-sectional study aims to assess the prevalence of dental caries in the first permanent molars of Egyptian children aged 6 to 7 years, and to examine how this caries status relates to the children's dietary habits and oral hygiene practices. A total of 272 children will undergo a clinical oral examination, and their parents or guardians will complete a structured questionnaire covering diet, tooth-brushing habits, and socio-demographic background. The findings are intended to help identify risk factors associated with early caries in these key teeth, supporting better-targeted preventive dental care for this age group.
Detailed description
First permanent molars are the earliest-erupting permanent teeth and, because they emerge without replacing a primary tooth, they are particularly susceptible to plaque accumulation and early carious lesions. As they account for a large proportion of dental caries in school-aged children, their eruption period represents a critical window for preventive interventions such as pit-and-fissure sealants.
Dental caries remains one of the most prevalent chronic diseases in childhood worldwide, with a multifactorial etiology involving diet, sugar consumption, salivary factors, fluoride exposure, and oral hygiene behavior. In Egypt, population-level data on the caries status of first permanent molars specifically - as opposed to caries in the dentition generally - remain limited.
This study will use a cross-sectional observational design conducted in the Paediatric Dentistry Department at October University for Modern Sciences and Arts (Giza, Egypt). Children aged 6-7 years who meet the eligibility criteria (healthy, no history of radiotherapy/chemotherapy, no retained primary teeth or developmental anomalies affecting the permanent dentition, no orthodontic treatment, and provision of parental informed consent) will be enrolled.
Each participating child will receive an intraoral clinical examination using a mirror and CPI probe, following WHO Oral Health Survey (2013) criteria, to assess caries status of the first permanent molars using the DMFT index and to record eruption pattern. Parents/guardians will complete a pre-tested, structured questionnaire (translated into Arabic) capturing dietary habits, tooth-brushing frequency, flossing, sweets intake, dental check-up frequency, fluoride toothpaste use, and socio-demographic variables (child's sex, number of children in the family, parental education).
Based on a previously reported FPM caries prevalence of 5.5%, a sample size of 272 children was calculated (97% confidence interval, 3% margin of error, with finite population correction, using Epi Info v7.2.5.0)
Study design
- Observational model
- Other
- Time perspective
- Cross-sectional
- Target follow-up
- 1 Day
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Arm A: children aged 6-7 years | – | –healthy children aged 6 to 7 years old to examine their first permanent molars |
Who may qualify
- Ages
- 6 to 7 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child
- Study population
- children Aged 6-7 years presented to the Paediatric Dentistry Department, Faculty of Dentistry, October University for Modern Sciences and Arts, and nurses residing in Giza City.
Key inclusion criteria (3 listed)
- Age: 6 to 7 years old children
- Children with written informed consent from their parents or guardians were included
- Healthy child
Key exclusion criteria (5 listed)
- Previous history/current radiotherapy and/or chemotherapy.
- Presence of retained primary teeth or congenital or developmental anomalies affecting the permanent dentition.
- Missing teeth due to causes other than dental caries.
- Subjects undergoing orthodontic therapy, which might preclude normal tooth brushing.
- Subjects who, in the opinion of the Investigator, may be non-compliant with study procedures.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
DMFT
Time frame: baseline
Measuring DMFT index for first permanent molars
3 secondary outcomes
DMFS
Time frame: baseline
Oral hygiene habits
Time frame: baseline
Dietary habits
Time frame: baseline
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 24 Jul 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Questions about this trial
What is this clinical trial studying?
An observational study of Dental Caries, run by October University for Modern Sciences and Arts.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 24 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Noor Mohamed Hanafy, General Dentist (00201033475613, noor.mohamed5@msa.edu.eg), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
DMFT (time frame: baseline). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 24 Jul 2026.