Psychological Well-BeingNCT07740148
Human-Created vs AI-generated Art on Immediate Psychological Responses
A study testing Human-created Animated Art Film and AI-generated Comparator Film in people with Psychological Well-Being, run by Stanford University at 2 sites in United States.
Trial summary
This online randomized controlled trial will evaluate the immediate psychological effects of a brief human-created animated art film. U.S.-based adults recruited through Prolific will be randomized in Stanford Qualtrics to view a human-created animated art film, view an AI-created comparison video, or to a do-nothing… Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Psychological Well-Being
- What is being tested?
- Human-created Animated Art Film and AI-generated Comparator Film
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 4,500 participants
- Where
- 2 sitesUnited States
- Study dates
- 31 Jul 2026to Dec 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Resides in the United States
- Able to read and understand English
- Current Prolific participant
- Able to provide electronic informed consent
- Able to complete the study online using a computer or mobile device with internet access
Who cannot join
- Residence outside the United States
- Unable to read and understand English sufficiently to complete the study
- Does not provide electronic informed consent
- Prior participation in this study
Trial locations and contacts
2 sites in 1 country. Contact the study team or a site near you to ask about taking part.
United States2 sites, 2 recruiting
- Enrolling by invitation
Prolific Academic Online Academic Research Platform
Palo Alto, California, 94304
- Recruiting
Stanford University
Stanford, California, 94305
Maya Adam, MD, PhD, 650-839-3600, madam@stanford.edu
About this study
Official title: Immediate Psychological Effects of a Brief Human-Created Animated Art Film: A Three-Arm Online Randomized Controlled Trial
This online randomized controlled trial will evaluate the immediate psychological effects of a brief human-created animated art film. U.S.-based adults recruited through Prolific will be randomized in Stanford Qualtrics to view a human-created animated art film, view an AI-created comparison video, or to a do-nothing control arm. Outcomes will be assessed immediately after exposure.
- Conditions
- Psychological Well-Being
- Being tested
- Human-created Animated Art Film, AI-generated Comparator Film
- Keywords
- Animated video, digital human-created art, AI-generated art, moral elevation, social connection, empathy, hope, artificial intelligence
- Medical subject headings
- Psychological Well-Being
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Human-created Animated Art FilmOther
A brief, ~3min human-created art film featuring 2D animation, dance, song and instrumental music.
AI-generated Comparator FilmOther
A brief, ~3min AI-generated film featuring 2D animation, dance, song and instrumental music.
| Study group | Role | What they receive |
|---|---|---|
| Human-Created Animated Art Film | Experimental | Participants view the brief human-created animated art film Thought of You. Receives: Other: Human-created Animated Art Film |
| AI-Created Comparison Video | Experimental | Participants view a brief AI-created comparison video. Receives: Other: AI-generated Comparator Film |
| Do-nothing Control | No intervention | Participants do not receive any intervention. |
What is being measured
The primary outcome is the main question the study is designed to answer.
State Moral Elevation
State moral elevation is assessed using a 9-item State Moral Elevation Scale. Each item is rated from 0 (Not at all) to 4 (Extremely). Item scores are summed to produce a total score ranging from 0 to 36, with higher scores indicating greater state moral elevation.
Measured: Immediately after assigned exposure, within the single study session (approximately 10 minutes after enrollment).
Secondary outcomes (4)
Change From Baseline in State Empathic Concern
State empathic concern is assessed using 4 items adapted from Batson's empathic concern scale: compassionate, sympathetic, warm, and tender. Each item is rated from 1 (Not at all) to 5 (Extremely). Item scores are summed to produce a total score ranging from 4 to 20, with higher scores indicating greater empathic concern.
Measured: Baseline and immediately after assigned exposure, within the single study session.
Change From Baseline in State Social Connection
State social connection is assessed using the 10-item University of British Columbia State Social Connection Scale. Each item is rated from 1 (Strongly disagree) to 7 (Strongly agree). Negatively worded items are reverse scored and item scores are summed, yielding a total score from 10 to 70; higher scores indicate greater state social connection.
Measured: Baseline and immediately after assigned exposure, within the single study session
Change From Baseline in State Hope
State hope is assessed using the 6-item State Hope Scale. Each item is rated from 1 (Definitely false) to 8 (Definitely true). Item scores are summed to produce a total score ranging from 6 to 48, with higher scores indicating greater state hope.
Measured: Baseline and immediately after assigned exposure, within the single study session.
Change From Baseline in Motivation to Improve Close Relationships
Motivation to put effort into improving close relationships is assessed with one investigator-developed visual analogue scale ranging from 1-100, with higher scores indicating greater motivation.
Measured: Baseline and immediately after assigned exposure, within the single study session.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted31 Jul 2026
- Study start31 Jul 2026
- Primary completion21 Aug 2026
- Study completionDec 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Psychological Well-BeingStudies of the same condition, open and under way.
- More trials run by Stanford UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 4,500 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Stanford University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Maya Adam, Stanford University
- Investigators
- Maya Adam, MD, PhD, Principal investigator, Stanford University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07740148
- Sponsor's protocol ID
- 86234
- Status last verified
- Aug 2026
- First submitted
- 28 Jul 2026
- Last updated
- 24 Aug 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 24 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Immediate Psychological Effects of a Brief Human-Created Animated Art Film: A Three-Arm Online Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT07740148
- Acronym / sponsor ID
- 86234
- Conditions
- Psychological Well-Being
- Keywords
- Animated video, digital human-created art, AI-generated art, moral elevation, social connection, empathy, hope, artificial intelligence
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 4,500 participants (estimated)
- Lead sponsor
- Stanford UniversityUniversity, hospital or other
- Study start
- 31 Jul 2026 (actual)
- Primary completion
- 21 Aug 2026 (actual)
- Study completion
- Dec 2026 (estimated)
- First posted
- 31 Jul 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This online randomized controlled trial will evaluate the immediate psychological effects of a brief human-created animated art film. U.S.-based adults recruited through Prolific will be randomized in Stanford Qualtrics to view a human-created animated art film, view an AI-created comparison video, or to a do-nothing control arm. Outcomes will be assessed immediately after exposure.
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| Human-Created Animated Art Film | Experimental | Other: Human-created Animated Art FilmParticipants view the brief human-created animated art film Thought of You. |
| AI-Created Comparison Video | Experimental | Other: AI-generated Comparator FilmParticipants view a brief AI-created comparison video. |
| Do-nothing Control | No intervention | –Participants do not receive any intervention. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (5 listed)
- Resides in the United States
- Able to read and understand English
- Current Prolific participant
- Able to provide electronic informed consent
- Able to complete the study online using a computer or mobile device with internet access
Key exclusion criteria (4 listed)
- Residence outside the United States
- Unable to read and understand English sufficiently to complete the study
- Does not provide electronic informed consent
- Prior participation in this study
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Human-created Animated Art FilmA brief, ~3min human-created art film featuring 2D animation, dance, song and instrumental music. | Other | Human-Created Animated Art Film |
| AI-generated Comparator FilmA brief, ~3min AI-generated film featuring 2D animation, dance, song and instrumental music. | Other | AI-Created Comparison Video |
Primary outcome
State Moral Elevation
Time frame: Immediately after assigned exposure, within the single study session (approximately 10 minutes after enrollment).
State moral elevation is assessed using a 9-item State Moral Elevation Scale. Each item is rated from 0 (Not at all) to 4 (Extremely). Item scores are summed to produce a total score ranging from 0 to 36, with higher scores indicating greater state moral elevation.
4 secondary outcomes
Change From Baseline in State Empathic Concern
Time frame: Baseline and immediately after assigned exposure, within the single study session.
Change From Baseline in State Social Connection
Time frame: Baseline and immediately after assigned exposure, within the single study session
Change From Baseline in State Hope
Time frame: Baseline and immediately after assigned exposure, within the single study session.
Change From Baseline in Motivation to Improve Close Relationships
Time frame: Baseline and immediately after assigned exposure, within the single study session.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 24 Aug 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Maya Adam, MD, PhD principal investigator
Stanford University
2 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Human-created Animated Art Film and AI-generated Comparator Film in people with Psychological Well-Being, run by Stanford University at 2 sites in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 24 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 2 sites in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Maya Adam, MD, PhD (6508393600, madam@stanford.edu), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
State Moral Elevation (time frame: Immediately after assigned exposure, within the single study session (approximately 10 minutes after enrollment).). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 24 Aug 2026.