Male InfertilityNCT07740161
A Clinical Trial to Evaluate the Effects of a Supplement on Markers of Male Fertility
A study testing WeNatal For Him Supplement in people with Male Infertility and Low Sperm Quality, run by WeNatal at 1 site in United States.
Trial summary
This study will evaluate the effects of the WeNatal For Him supplement on markers of male fertility over a 3-month period. The trial is a single-arm, unblinded study enrolling 40 male participants who will take 3 capsules of the test product daily in the morning with their first meal. Read more about this study
- Who is it for?
- Ages 30 years and olderHealthy volunteers can take part
- Conditions the study is for
- Male Infertility, Low Sperm Quality, Low Testosterone
- What is being tested?
- WeNatal For Him Supplement
- Type of treatment
- Pill or oral medicine
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 40 participants
- Where
- 1 siteUnited States
- Study dates
- 14 Apr 2025to 15 Sep 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 30 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Be male
- Be aged 30+
- Anyone currently experiencing issues regarding low energy and low libido
- Anyone who is generally healthy - does not live with any uncontrolled chronic disease
- Willing to stop taking any other products or prescription medication, herbal remedies, or supplements for the duration of the study that target fertility, reproductive health, and sexual health
- Not planning on introducing any products or any new prescription medication, herbal remedies, or supplements that target male fertility, reproductive health, or sexual health for the study duration
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- Resides in the United States
- Not currently partaking in another research study and will not be partaking in any other research study for the next 3 months and at any point during this study's duration
- Willing to provide a semen sample via masturbation
- Willing to abstain from ejaculation for a minimum of 48 hours and a maximum of 5 days before providing the semen sample
- Willing to abstain from marijuana products during the entire study duration
Who cannot join
- Anyone with pre-existing chronic conditions that would prevent participants from adhering to the protocol, including oncological and psychiatric disorders
- Anyone who has ever taken supplemental testosterone
- Anyone planning to undergo any surgeries or invasive treatments for the study duration
- Anyone who has had a major illness in the last 3 months
- Anyone currently undergoing any type of fertility treatment
- Anyone with any allergies or sensitivities to any of the study product ingredients
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- Anyone unwilling to follow the study protocol
- Anyone taking anticoagulant or 'blood thinner' medication
- Anyone undergoing chemotherapy
- Anyone taking insulin or diabetes medication
- Anyone who drinks heavily (i.e. 8 or more alcoholic drinks per week for women or 15 or more alcoholic drinks per week for men)
- Anyone with a history of substance abuse
- Anyone who is currently a smoker or has been a smoker in the past 3 months
Trial locations and contacts
1 site in 1 country.
About this study
This study will evaluate the effects of the WeNatal For Him supplement on markers of male fertility over a 3-month period. The trial is a single-arm, unblinded study enrolling 40 male participants who will take 3 capsules of the test product daily in the morning with their first meal.
Participants will complete questionnaires at Baseline, Month 1, Month 2, and Month 3. Semen analysis will be conducted at home at Baseline and Month 3, and blood testing will be performed at a local Labcorp location at Baseline and Month 3. The primary focus is on sperm quality parameters and testosterone levels, while secondary endpoints capture participants' perceptions of changes in reproductive and sexual health, including energy and libido.
- Conditions
- Male Infertility, Low Sperm Quality, Low Testosterone, Low Energy, Low Libido
- Being tested
- WeNatal For Him Supplement
- Medical subject headings
- Infertility, Male
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
WeNatal For Him SupplementDietary supplement
All participants take 3 capsules of the WeNatal For Him supplement daily in the morning with their first meal for 3 months.
| Study group | Role | What they receive |
|---|---|---|
| WeNatal For Him Supplement | Experimental | Not described Receives: Dietary Supplement: WeNatal For Him Supplement |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in Testosterone (Free and Total)
Assessed via blood test at a local Labcorp location measuring free and total testosterone levels
Measured: Baseline and Month 3
Change in Sperm Volume
Assessed via at-home semen analysis using the Fellow Semen Analysis kit
Measured: Baseline and Month 3
Change in Sperm Concentration
Assessed via at-home semen analysis using the Fellow Semen Analysis kit
Measured: Baseline and Month 3
Change in Sperm Count
Assessed via at-home semen analysis using the Fellow Semen Analysis kit
Measured: Baseline and Month 3
Change in Sperm Motility
Assessed via at-home semen analysis using the Fellow Semen Analysis kit
Measured: Baseline and Month 3
Change in Total Motile Count
Assessed via at-home semen analysis using the Fellow Semen Analysis kit
Measured: Baseline and Month 3
Change in Sperm Morphology
Assessed via at-home semen analysis using the Fellow Semen Analysis kit
Measured: Baseline and Month 3
Change in 25-hydroxy Vitamin D
Assessed via blood test at a local Labcorp location
Measured: Baseline and Month 3
Change in hs-CRP
Assessed via blood test at a local Labcorp location
Measured: Baseline and Month 3
Change in Homocysteine
Assessed via blood test at a local Labcorp location
Measured: Baseline and Month 3
Secondary outcomes (3)
Change in Self-Reported Reproductive Health
Assessed via self-reported questionnaire
Measured: Baseline, Month 1, Month 2, and Month 3
Change in Self-Reported Energy
Assessed via self-reported questionnaire
Measured: Baseline, Month 1, Month 2, and Month 3
Change in Self-Reported Libido
Assessed via self-reported questionnaire
Measured: Baseline, Month 1, Month 2, and Month 3
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted31 Jul 2026
- Study start14 Apr 2025
- Primary completion15 Sep 2025
- Study completion15 Sep 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Male InfertilityStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 40 participants (actual)
Sponsor and investigators
- Lead sponsor
- WeNatal
- Sponsor type
- Industry (pharma, biotech, devices)
- Collaborators
- Citruslabs
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07740161
- Sponsor's protocol ID
- 20728
- Other IDs
- legacy-20728
- Status last verified
- Jul 2026
- First submitted
- 28 Jul 2026
- Last updated
- 31 Jul 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 31 Jul 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- A Clinical Trial to Evaluate the Effects of a Supplement on Markers of Male Fertility
- ClinicalTrials.gov ID
- NCT07740161
- Acronym / sponsor ID
- 20728
- Conditions
- Male Infertility, Low Sperm Quality, Low Testosterone, Low Energy, Low Libido
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 40 participants (actual)
- Lead sponsor
- WeNatalIndustry (pharma, biotech, devices)
- Collaborators
- Citruslabs
- Study start
- 14 Apr 2025 (actual)
- Primary completion
- 15 Sep 2025 (actual)
- Study completion
- 15 Sep 2025 (actual)
- First posted
- 31 Jul 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study will evaluate the effects of the WeNatal For Him supplement on markers of male fertility over a 3-month period. The trial is a single-arm, unblinded study enrolling 40 male participants who will take 3 capsules of the test product daily in the morning with their first meal.
Participants will complete questionnaires at Baseline, Month 1, Month 2, and Month 3. Semen analysis will be conducted at home at Baseline and Month 3, and blood testing will be performed at a local Labcorp location at Baseline and Month 3. The primary focus is on sperm quality parameters and testosterone levels, while secondary endpoints capture participants' perceptions of changes in reproductive and sexual health, including energy and libido.
Study design
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| WeNatal For Him Supplement | Experimental | Dietary Supplement: WeNatal For Him Supplement |
Who may qualify
- Ages
- 30 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (11 listed)
- Be male
- Be aged 30+
- Anyone currently experiencing issues regarding low energy and low libido
- Anyone who is generally healthy - does not live with any uncontrolled chronic disease
- Willing to stop taking any other products or prescription medication, herbal remedies, or supplements for the duration of the study that target fertility, reproductive health, and sexual health
Key exclusion criteria (13 listed)
- Anyone with pre-existing chronic conditions that would prevent participants from adhering to the protocol, including oncological and psychiatric disorders
- Anyone who has ever taken supplemental testosterone
- Anyone planning to undergo any surgeries or invasive treatments for the study duration
- Anyone who has had a major illness in the last 3 months
- Anyone currently undergoing any type of fertility treatment
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| WeNatal For Him SupplementAll participants take 3 capsules of the WeNatal For Him supplement daily in the morning with their first meal for 3 months. | Dietary supplement | WeNatal For Him Supplement |
Primary outcome
Change in Testosterone (Free and Total)
Time frame: Baseline and Month 3
Assessed via blood test at a local Labcorp location measuring free and total testosterone levels
Change in Sperm Volume
Time frame: Baseline and Month 3
Assessed via at-home semen analysis using the Fellow Semen Analysis kit
Change in Sperm Concentration
Time frame: Baseline and Month 3
Assessed via at-home semen analysis using the Fellow Semen Analysis kit
Change in Sperm Count
Time frame: Baseline and Month 3
Assessed via at-home semen analysis using the Fellow Semen Analysis kit
Change in Sperm Motility
Time frame: Baseline and Month 3
Assessed via at-home semen analysis using the Fellow Semen Analysis kit
Change in Total Motile Count
Time frame: Baseline and Month 3
Assessed via at-home semen analysis using the Fellow Semen Analysis kit
Change in Sperm Morphology
Time frame: Baseline and Month 3
Assessed via at-home semen analysis using the Fellow Semen Analysis kit
Change in 25-hydroxy Vitamin D
Time frame: Baseline and Month 3
Assessed via blood test at a local Labcorp location
Change in hs-CRP
Time frame: Baseline and Month 3
Assessed via blood test at a local Labcorp location
Change in Homocysteine
Time frame: Baseline and Month 3
Assessed via blood test at a local Labcorp location
3 secondary outcomes
Change in Self-Reported Reproductive Health
Time frame: Baseline, Month 1, Month 2, and Month 3
Change in Self-Reported Energy
Time frame: Baseline, Month 1, Month 2, and Month 3
Change in Self-Reported Libido
Time frame: Baseline, Month 1, Month 2, and Month 3
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 31 Jul 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing WeNatal For Him Supplement in people with Male Infertility and Low Sperm Quality, run by WeNatal at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 11 inclusion and 13 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 31 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in Testosterone (Free and Total) (time frame: Baseline and Month 3). The study lists 10 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 31 Jul 2026.