Clinical trials: Low Testosterone
Sex Behavior
Safety Study of Transdermal Testosterone for Low Libido in Pre and Postmenopausal Women
Female sexual dysfunction (FSD) is an established side effect of Selective serotonin reuptake inhibitors (SSRIs) and serotonin noradrenalin reuptake inhibitors (SNRIs), causing symptoms such as loss of libido, arousal…
- Trial name
- TESTOSTERONE (NCT02215434)
- Testing
- Testosterone, Transdermal, Behavior
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Potiguar
Other Complications Associated With Artificial Fertilization
Efficacy of Luteinizing Hormone (LH) Activity in Low Responder Patients With Transdermal Testosterone
The investigators have previously demonstrated the utility of transdermal testosterone in in vitro fertilization (IVF) low responder patients.
- Trial name
- NCT01291212
- Testing
- Testosterone and FSHr-LHr, testosterone and FSHr alone
- Where
- Spain
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
Hypogonadism, Low Testosterone
A One Year Open Label Study for the Treatment of Hypogonadism (Low Testosterone) in Men Who Have Completed ZA-203
The purpose of this study is to determine the continued effects of Androxal on morning testosterone and reproductive status in men with secondary hypogonadism who have completed protocol ZA-203.
- Trial name
- NCT01386567
- Testing
- Androxal (enclomiphene citrate), Testim (topical testosterone)
- Where
- 8 sites in United States
- Volunteers
- 48 people
- Sponsor
- Repros Therapeutics Inc.
Mobility Limitation
Optimizing Protein Intake in Older Americans With Mobility Limitations
This will be a randomized, placebo-controlled, parallel group, double blind, clinical trial in community dwelling, older men, 65 years of age or older, who have mobility limitation and low protein intake.
- Trial name
- OPTIMen (NCT01275365)
- Testing
- Testosterone enanthate
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Brigham and Women's Hospital
Metabolic Syndrome
Testosterone Therapy in Men With Low Testosterone Levels and Metabolic Syndrome or Early Stages of Type 2 Diabetes
Men with metabolic syndrome often have lower than normal testosterone levels and low testosterone levels have been suggested to predispose for development of type2 diabetes.
- Trial name
- NCT00479609
- Testing
- Transdermal testosterone therapy
- Where
- Sweden
- Volunteers
- 176 people
- Sponsor
- Karolinska Institutet
Ovarian Diseases
Antral Follicle Priming Prior to ICSI (Intracytoplasmic Sperm Injection) in Previously Diagnosed Low Responders
The aim of this study is to compare the effectiveness of testosterone,estradiol and a combined treatment with estrogens/progestagens prior to IVF-ICSI in previously diagnosed low responder patients.
- Trial name
- FOLLPRIM (NCT01310647)
- Testing
- Testosterone, Estradiol, CombEq
- Where
- Spain
- Volunteers
- 66 people
- Sponsor
- Instituto de Investigacion Sanitaria La Fe
Peyronie's Disease
Testosterone Pellets Plus Vitamin D and E Versus Vitamin D and E Alone for the Treatment of Peyronie's Disease
Two recent studies have identified low levels of serum testosterone in association with Peyronie's Disease (PD), with a significant correlation noted between severity of testosterone deficiency and severity of curvature.
- Trial name
- PD+ (NCT01578473)
- Testing
- Vitamin D2, Vitamin E, Testosterone Pellets
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Men's Health Boston
Hypogonadism, Testosterone Deficiency
An Efficacy and Safety Study of ABT-SLV176 for the Treatment of Hypogonadal Men
This is an open-study with a 26 week open label treatment period followed by an optional 26 week open label extension. The total treatment period will be 52 weeks.
- Trial name
- NCT02082197
- Testing
- ABT-SLV176
- Where
- 42 sites in United States
- Sponsor
- AbbVie
Secondary Hypogonadism
A Randomized, Double Blind, Placebo-Controlled, Multi-Center Phase III Study in Men With Acquired Hypogonadotropic Hypogonadism to Compare Changes in Testosterone and Sperm Concentration Following Treatment With 12.5 mg or 25 mg Androxal or AndroGel 1.62%
This is a Randomized, Double Blind, Placebo-Controlled, Multi-Center Phase III Study in Men with Acquired Hypogonadotropic Hypogonadism to Compare Changes in Testosterone and Sperm Concentration Following Treatment with the 12.5…
- Trial name
- NCT01993212
- Testing
- Androxal 12.5 mg or 25 mg, AndroGel 1.62%
- Where
- 8 sites in United States
- Volunteers
- 120 people
- Sponsor
- Repros Therapeutics Inc.
Localized Prostate Carcinoma, Stage I Prostate Cancer AJCC v8
Testosterone Replacement Therapy for the Treatment of Low Testosterone in Hypogonadal Men With Localized Prostate Cancer on Active Surveillance
This phase IV trial studies the effects of testosterone replacement therapy (TRT) on treatment outcomes in hypogonadal men with prostate cancer that has not spread to other parts of the body (localized) and who are on active…
- Conditions
- Localized Prostate Carcinoma, Stage I Prostate Cancer AJCC v8, Stage II Prostate Cancer AJCC v8, Stage III Prostate Cancer AJCC v8
- Trial name
- NCT06733350
- Testing
- Biopsy of Prostate, Biospecimen Collection, Magnetic Resonance Imaging
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Roswell Park Cancer Institute
Multiple Sclerosis, Erectile Dysfunction
Testosterone Treatment for Erectile Dysfunction and Multiple Sclerosis
The purpose of the study is to determine the effects of testosterone treatment on erectile function, fatigue, depression, cognitive function, quality of life, urinary incontinence, pain, and damage to neurons in male Multiple…
- Conditions
- Multiple Sclerosis, Erectile Dysfunction, Testosterone Deficiency
- Trial name
- NCT04601233
- Testing
- XYOSTED 75 milligram (mg) in 0.5 ML Auto-Injector
- Where
- United States
- Sponsor
- Tulane University
Gonadal Dysfunction, Gonadal Failure
Fertility Enhancement Through Regenerative Treatment in Ovaries and Testes
This study investigates the safety and efficacy of stem cell or stem cell-derived exosome therapy for gonadal failure, including testicular failure, hypogonadism, ovarian insufficiency, and premature ovarian failure (POF).
- Conditions
- Gonadal Dysfunction, Gonadal Failure, Azoospermia, Testosterone Deficiency
- Trial name
- FERTILE (NCT06841328)
- Testing
- Stem cells
- Where
- United Arab Emirates
- Volunteers
- 60 people
- Sponsor
- Jumeirah American Clinic
Sleep Apnea, Obstructive, Sleep Apnea
Sexual Dysfunction And Hypotestosteronemia In Patients With Obstructive Sleep Apnea Syndrome
Obstructive Sleep Apnea Syndrome (OSAS)is a common disease and is suspected to be associated with sexual dysfunction. Our purpose is to sudy the effect of CPAP (Continuous Positive Airway Pressure) treatment on patients' sexual…
- Conditions
- Sleep Apnea, Obstructive, Sleep Apnea, Hypotestosteronism
- Trial name
- NCT00832065
- Where
- 2 sites in United States
- Sponsor
- Lahey Clinic
Aging, Low DHEA for Women
DHEA and Testosterone Replacement in Elderly
Sarcopenia is a major health problem among the rapidly expanding elderly population in our society. Disabilities directly related to muscle weakness, and indirectly related to changes in body composition and metabolic…
- Conditions
- Aging, Low DHEA for Women, Low Testosterone and DHEA for Men
- Trial name
- NCT00254371
- Testing
- Androgen Replacement
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Hypoactive Sexual Desire Disorder (HSDD)
Study to Assess the Efficacy/Safety of Transdermal Testosterone Patches in Naturally Menopausal Women With Low Libido
This study is designed to evaluate efficacy and safety of a testosterone patch as treatment for low libido in naturally menopausal women who are taking estrogen or estrogen/progestin therapy.
- Trial name
- NCT00349791
- Testing
- Testosterone Transdermal System
- Where
- 3 sites in United States, Australia and 1 more
- Volunteers
- 549 people
- Sponsor
- Warner Chilcott
Heart Failure
Assessing the Safety/Efficacy of Transdermal Testosterone in Female Patients With Symptomatic Heart Failure
Heart failure (HF) is a complex condition resulting from structural or functional heart diseases that impair the ability of the heart to fill with or pump out blood.
- Trial name
- CORDELIA (NCT00957034)
- Testing
- testosterone
- Where
- 16 sites in United States
- Volunteers
- 17 people
- Sponsor
- Warner Chilcott
Hypogonadism
Cycled Testosterone Replacement Study
The purpose of this study is to determine whether testosterone (male hormone) therapy is effective if administered in a cyclic fashion (periodic dosing) compared to continuous dosing in men aged 60 to 85 years.
- Trial name
- NCT00957528
- Testing
- Testosterone
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Cancer Survivor, Sexual Dysfunction
Low-Dose Testosterone in Improving Libido in Postmenopausal Female Cancer Survivors
RATIONALE: The hormone testosterone may improve the libido (sex drive) in women. It is not yet known whether testosterone is effective in improving libido in female cancer survivors.
- Conditions
- Cancer Survivor, Sexual Dysfunction, Sexuality and Reproductive Issues, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT00075855
- Testing
- therapeutic testosterone
- Where
- 16 sites in United States
- Volunteers
- 150 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Male Hypogonadism
Safety and Efficacy Trial of Testosterone Undecanoate
The purpose of the study is to determine if oral testosterone undecanoate is effective and safe in the treatment of low testosterone in men.
- Trial name
- NCT01765179
- Testing
- Oral testosterone undecanoate
- Where
- 27 sites in United States
- Volunteers
- 144 people
- Sponsor
- Clarus Therapeutics, Inc.
Circadian, Exercise
Diagnostic Relevance of Salivary Testosterone Concentrations in Doping Control.
It is generally accepted that chemical testing of biologic fluids is the most objective means of diagnosis of drug use. In recent years saliva has attracted much attention.
- Conditions
- Circadian, Exercise, Testosterone
- Trial name
- NCT02134470
- Testing
- Testosterone supplementation
- Where
- Germany
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Paracelsus Medical University