Turbinate HypertrophyNCT07745868
Adenoidectomy With or Without Partial Inferior Turbinectomy for Pediatric Nasal Obstruction
A study testing adenoidectomy and Adenodiectomy and bilateral partial infeiror turbienctomy in people with Turbinate Hypertrophy and Adenoidectomy, run by Al-Azhar University at 1 site in Egypt.
Trial summary
Nasal obstruction is a common problem in children and is frequently caused by adenoid hypertrophy with concomitant inferior turbinate hypertrophy, leading to sleep-disordered breathing and reduced quality of life. Read more about this study
- Who is it for?
- Ages 6 to 18 years
- Conditions the study is for
- Turbinate Hypertrophy, Adenoidectomy, Adenoid Hypertrophy
- What is being tested?
- adenoidectomy and Adenodiectomy and bilateral partial infeiror turbienctomy
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 60 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Sep 2025to 1 Jul 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 6 to 18 years
- All sexes
- No healthy volunteers
- Child, Adult
Who may be able to join
- Age : children (9 - 18 years old ) only.
- Patients with bilateral nasal obstruction or sleep-disordered breathing, and having adenoid hypertrophy diagnosed by nasal endoscopy, with bilateral inferior turbinate hypertrophy investigated by CT and confirmed by endoscopy despite 3 months of medical treatment with intranasal corticosteroid and oral antihistaminic.
- Sex : both males and females.
- Patients were selected from the otorhinolaryngology outpatient clinic of Al-Azhar University hospital in Assiut in a consecutive manner.
- All patients were generally well and fit for surgery.
Who cannot join
- • Patients with recent upper respiratory tract infection.
- Evidence of any bleeding disorders .
- Patients with serous otitis media and chronic tonsillitis.
- patients contraindicated to do adenoidectomy after phoniatric consultation.
- patients with atrophic rhinitis
- patients with nasal obstruction due to other causes such as : deviated nasal septum and antrochoanal polyp.
- Patients with sinonasal pathology like a marked septal deviation or nasal polyposis, and those exhibiting symptoms that could indicate chronic or recurrent rhinosinusitis, such as fever, headaches, facial pain, rhinorrhea, antibiotic requirements, and purulence seen on nasal endoscopy.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: The Effect of Adenoidectomy With or Without Endoscopic Bilateral Partial Inferior Turbinectomy on Children With Bilateral Nasal Obstruction
Nasal obstruction is a common problem in children and is frequently caused by adenoid hypertrophy with concomitant inferior turbinate hypertrophy, leading to sleep-disordered breathing and reduced quality of life. Although adenoidectomy is the standard treatment, persistent nasal obstruction may occur in some patients due to inferior turbinate enlargement. Recent evidence suggests that combining inferior turbinate reduction with adenoidectomy may provide superior relief of nasal obstruction and improve postoperative outcomes compared with adenoidectomy alone.
The study aims to compare the effectiveness of adenoidectomy alone versus adenoidectomy combined with endoscopic bilateral partial inferior turbinectomy in relieving nasal obstruction and sleep-disordered breathing in children with adenoid and bilateral inferior turbinate hypertrophy.
- Being tested
- adenoidectomy, Adenodiectomy and bilateral partial infeiror turbienctomy
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
adenoidectomyProcedure or surgery
Adenoidectomy by currattage assisted by suction coagulation
Adenodiectomy and bilateral partial infeiror turbienctomyProcedure or surgery
adenodiectomy by currattage assisted by suction coagulation and bilateral partial inferior turbienctomy
| Study group | Role | What they receive |
|---|---|---|
| patients presneted with adenoid hypertrophy | Active comparator | Patients who presented with adenoid hypertrophy and underwent adenoidectomy by curettage assisted by endoscopic suction coagulation Receives: Procedure: adenoidectomy |
| patients who presnted with adneoid hypereophy assicated with bilateral nferior turbiante hypertrophy | Active comparator | Patients who present with adenoid hypertrophy and bilateral inferior turbinate hypertrophy will undergo adenoidectomy by currattage, assisted by endoscopic suction coagulation and bilateral partial inferior turbinectomy Receives: Procedure: Adenodiectomy and bilateral partial infeiror turbienctomy |
What is being measured
The primary outcome is the main question the study is designed to answer.
operative time
operative duration in mintues
Measured: During the procedure
nasal obstruction
pre and post operative difeerence of nasal obstruction using nose score
Measured: preoperative till 2 months after opertaions
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted4 Aug 2026
- Study start1 Sep 2025
- Primary completion1 Jul 2026
- Study completion1 Jul 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Turbinate HypertrophyStudies of the same condition, open and under way.
- More trials run by Al-Azhar UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Masking
- Quadruple blind
- Who is masked
- Participant, Care provider, Investigator, Outcomes assessor
- Enrolment
- 60 participants (actual)
Sponsor and investigators
- Lead sponsor
- Al-Azhar University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Ahmed Nabil Selim, Al-Azhar University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07745868
- Sponsor's protocol ID
- MSCAZASTENT0301424792025
- Status last verified
- Sep 2025
- First submitted
- 30 Jul 2026
- Last updated
- 4 Aug 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 4 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effect of Adenoidectomy With or Without Endoscopic Bilateral Partial Inferior Turbinectomy on Children With Bilateral Nasal Obstruction
- ClinicalTrials.gov ID
- NCT07745868
- Acronym / sponsor ID
- MSCAZASTENT0301424792025
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 60 participants (actual)
- Lead sponsor
- Al-Azhar UniversityUniversity, hospital or other
- Study start
- 1 Sep 2025 (actual)
- Primary completion
- 1 Jul 2026 (actual)
- Study completion
- 1 Jul 2026 (actual)
- First posted
- 4 Aug 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Nasal obstruction is a common problem in children and is frequently caused by adenoid hypertrophy with concomitant inferior turbinate hypertrophy, leading to sleep-disordered breathing and reduced quality of life. Although adenoidectomy is the standard treatment, persistent nasal obstruction may occur in some patients due to inferior turbinate enlargement. Recent evidence suggests that combining inferior turbinate reduction with adenoidectomy may provide superior relief of nasal obstruction and improve postoperative outcomes compared with adenoidectomy alone.
The study aims to compare the effectiveness of adenoidectomy alone versus adenoidectomy combined with endoscopic bilateral partial inferior turbinectomy in relieving nasal obstruction and sleep-disordered breathing in children with adenoid and bilateral inferior turbinate hypertrophy.
Study design
- Primary purpose
- Treatment
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Masking
- Quadruple blind (participant, care provider, investigator, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| patients presneted with adenoid hypertrophy | Active comparator | Procedure: adenoidectomyPatients who presented with adenoid hypertrophy and underwent adenoidectomy by curettage assisted by endoscopic suction coagulation |
| patients who presnted with adneoid hypereophy assicated with bilateral nferior turbiante hypertrophy | Active comparator | Procedure: Adenodiectomy and bilateral partial infeiror turbienctomyPatients who present with adenoid hypertrophy and bilateral inferior turbinate hypertrophy will undergo adenoidectomy by currattage, assisted by endoscopic suction coagulation and bilateral partial inferior turbinectomy |
Who may qualify
- Ages
- 6 to 18 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult
Key inclusion criteria (5 listed)
- Age : children (9 - 18 years old ) only.
Key exclusion criteria (7 listed)
- • Patients with recent upper respiratory tract infection.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| adenoidectomyAdenoidectomy by currattage assisted by suction coagulation | Procedure or surgery | patients presneted with adenoid hypertrophy |
| Adenodiectomy and bilateral partial infeiror turbienctomyadenodiectomy by currattage assisted by suction coagulation and bilateral partial inferior turbienctomy | Procedure or surgery | patients who presnted with adneoid hypereophy assicated with bilateral nferior turbiante hypertrophy |
Primary outcome
operative time
Time frame: During the procedure
operative duration in mintues
nasal obstruction
Time frame: preoperative till 2 months after opertaions
pre and post operative difeerence of nasal obstruction using nose score
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 4 Aug 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing adenoidectomy and Adenodiectomy and bilateral partial infeiror turbienctomy in people with Turbinate Hypertrophy and Adenoidectomy, run by Al-Azhar University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 4 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
operative time (time frame: During the procedure). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 4 Aug 2026.