Clinical trials: Adenoid Hypertrophy
Adenoids Hypertrophy
Efficacy and Safety of Mometasone Furoate Nasal Spray in Children With Adenoid Hypertrophy. SNORE Study (P05155)
The purpose of this study is to determine whether 8 weeks treatment with mometasone furoate nasal spray (MFNS), twice daily, is safe and effective in treating adenoid hypertrophy in children.
- Trial name
- SNORE (NCT00552032)
- Testing
- Mometasone Furoate nasal spray
- Volunteers
- 132 people
- Sponsor
- Organon and Co
Enlargement of Tonsil or Adenoid
Bioclinical Profile of Adenotonsillar Hypertrophy in the Pediatric Population
Adenotonsillar hypertrophy is the principal cause of obstructive sleep apnea of childhood, yet little is known with regard to its pathophysiologic and molecular mechanisms.
- Trial name
- NCT03541434
- Testing
- Complete Blood Count, Tympanometry, Tonsillectomy and/or adenoidectomy
- Where
- 2 sites in Greece
- Volunteers
- 134 people
- Sponsor
- University of Patras
Children, Only, Tonsillar Hypertrophy
Lidocaine Infusion for Pain Relief in Children Scheduled for Tonsillectomy and Adenoidectomy
Lidocaine is widely available and is a very commonly used local anesthetic. When administered intravenously, lidocaine infusions have anti-inflammatory effects and have significantly decreased the reliance on opioid use for…
- Conditions
- Children, Only, Tonsillar Hypertrophy, Adenoid Hypertrophy
- Trial name
- NCT03902314
- Testing
- Lidocaine Iv, Saline Solution
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Rhode Island Hospital
Adenoid Hypertrophy
Conventional Curettage Versus Endoscopic Microdebrider-Assisted Adenoidectomy in Children
The purpose of this randomized clinical trial is to compare two surgical methods for removing enlarged adenoids in children: conventional curettage adenoidectomy and endoscopic microdebrider-assisted adenoidectomy.
- Trial name
- NCT07856771
- Testing
- Conventional Curretage Adenoidectomy, Endoscopic Microdebrider-Assisted Adenoidectomy
- Where
- Pakistan
- Volunteers
- 88 people
- Sponsor
- Allama Iqbal Teaching Hospital
Adenoid Hypertrophy, Adenoidectomy
Coblation Versus Suction Diathermy in Pediatric Adenoidectomy
The goal of this clinical trial is to compare two surgical procedures in endoscopic adenoidectomy including Coblation and Suction diathermy .
- Conditions
- Adenoid Hypertrophy, Adenoidectomy, Coblation Adenoidectomy, Suction Daithermy
- Trial name
- NCT06841432
- Testing
- adenoidectomy using coblatioion, adenoidectomy by Suction diathermy
- Where
- Egypt
- Volunteers
- 245 people
- Sponsor
- Al-Azhar University
Obstructive Sleep Apnea, Enlargement of Tonsil or Adenoid
Caffeine in Children With Obstructive Sleep Apnea, Dose Response Study
The aim of this study is to evaluate whether a smaller dose of caffeine sodium benzoate 10 mg/kg IV is as effective as 20 mg/kg IV in decreasing the number of children who develop post extubation adverse upper airway respiratory…
- Trial name
- NCT01349205
- Testing
- Caffeine and sodium Benzoate 10 mg/kg IV, Caffeine and Sodium Benzoate 20 mg/kg IV, 0.9 NS Saline
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Pulmonary Diseases, Tonsillar Hypertrophy
The Influence of Feeding Position on Pulmonary Morbidity in Young Children
Supine feeding position is associated with serous otitis media. The hypothesis is that supine feeding is associated with recurrent otitis media, tonsillar and adenoid hypertrophy and recurrent pneumonia secondary to recurrent…
- Conditions
- Pulmonary Diseases, Tonsillar Hypertrophy, Otitis Media, Dental Caries
- Trial name
- NCT00248391
- Testing
- upright feeding
- Where
- Israel
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Nasal Obstruction, Adenoids Hypertrophy
Placebo-controlled Trial With Nasonex for Nasal Obstruction Secondary to Adenoids Hypertrophy in Children (P04367)(TERMINATED)
This is a randomized, double-blind, placebo-controlled study to document the long-term effect of treatment with mometasone furoate nasal spray in moderate to severe adenoids hypertrophy as reflected by the need for removal of the…
- Conditions
- Nasal Obstruction, Adenoids Hypertrophy, Adenoidectomy
- Trial name
- NCT00553891
- Testing
- mometasone furoate nasal spray
- Sponsor
- Organon and Co
Sleep Breathing Disorders, Tonsillitis
Continuous Intravenous Sufentanil Infusion for Postoperative Pain Management Following Tonsillectomy or Adeno-tonsillectomy in Children
Postoperative pain following tonsillectomy or adeno-tonsillectomy in children is severe and sometimes last for days. Sufentanil is used by epidural route for postoperative analgesia in children.
- Conditions
- Sleep Breathing Disorders, Tonsillitis, Adenoid Hypertrophy
- Trial name
- NCT02205580
- Testing
- continuous intravenous sufentanil 0.02μg•kg-1•h-1 infusion, continuous intravenous sufentanil 0.03μg•kg-1•h-1 infusion, continuous intravenous sufentanil 0.04μg•kg-1•h-1 infusion
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Jin Ni
Adenoid Hypertrophy
A Pilot Study: a Non-opioid Technique for Postoperative Adenoidectomy Pain Relief in Pediatric Patients
This proposed study will assess analgesic efficacy of a multi-modal, non-opioid analgesic regimen for providing surgical analgesia in pediatric patients undergoing adenoidectomy and to assess recovery characteristics in the…
- Trial name
- NCT03714919
- Testing
- Dextromethorphan, Acetaminophen, Dexmedetomidine
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Arlyne Thung
Adenoiditis Acute Infective
Relationship of Endoplasmic Reticulum Stress and Adenoid Diseases
Adenoid tissue is a significant organ for the performing of immune systems in children. The Endoplasmic Reticulum (ER), is an organelle needed for the care of a stable function of cells.
- Trial name
- NCT04583631
- Testing
- Adenoidectomy surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Selcuk University
Children, Only, Adenoidal Hypertrophy
Tongue Depressor-related Tongue Swelling
This study aimed to detect tongue swelling induced by the pressure exerted by tongue depressor; swelling detection was made through tongue surface area measurement using ultrasonography (USG) in pediatric patients who underwent…
- Conditions
- Children, Only, Adenoidal Hypertrophy, Adenoid Disease - Chronic, Complication
- Trial name
- NCT04256590
- Testing
- Ultrasonography imaging
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people
- Sponsor
- Selcuk University
Adenoid Hypertrophy, Tonsillar Hypertrophy
Evaluation of the Effects of Adenoidectomy and Adenotonsillectomy on Voice in Children
This prospective study aims to evaluate the effects of adenoidectomy and adenotonsillectomy on voice and speech functions in children.
- Conditions
- Adenoid Hypertrophy, Tonsillar Hypertrophy, Voice Disorders in Children
- Trial name
- NCT07399041
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Adenoids
Nasonex (Mometasone Furoate Nasal Spray) in Adenoids Hypertrophy in Children (P04367)
To document the short term \& long term effect of treatment with Nasonex (mometasone furoate nasal spray) in moderate to severe adenoids hypertrophy (which cause > 50% obstruction of the posterior choanae).
- Trial name
- NAHCh (NCT01098071)
- Testing
- mometasone furoate nasal spray
- Volunteers
- 34 people
- Sponsor
- Organon and Co
Adenoid Hypertrophy, Adenoid Hyperplasia
Effect of OM-85 on Respiratory Tract Infections and Adenoid Tissue in Children With Adenoid Hypertrophy
Clinical research question: Can OM-85 reduce the recurrence of respiratory tract infections (RTIs) in children with AH by stimulating the immunological response of the host and therefore, as a consequence reduce the size of…
- Conditions
- Adenoid Hypertrophy, Adenoid Hyperplasia, Respiratory Tract Infections, Preschool Children
- Trial name
- NCT03243565
- Testing
- OM-85
- Volunteers
- 68 people
- Sponsor
- Dr. Sami Ulus Children's Hospital
Adenoid Hypertrophy, Adenotonsillar Hypertrophy
Serum and Salivary Leptin Levels in Children With Adenoid/Adenotonsillar Hypertrophy
Adenoid and adenotonsillar hypertrophy are among the most common causes of nasal obstruction, snoring and sleep-disordered breathing in children, and chronic upper airway obstruction may affect growth, appetite and energy…
- Trial name
- NCT07887451
- Testing
- Blood and saliva sampling
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Harran University
Obstructive Sleep Apnea, Nasal Obstruction
Assessment of Adenoidal Obstruction in Children : Clinical Signs Versus Flexible Nasal Endoscopy and Roentgenographic Findings
The term adenoids describes lymphoid tissue on the superior and posterior walls of the nasopharynx, and their hypertrophy is a common condition of childhood.
- Trial name
- NCT01965457
- Where
- Israel
- Volunteers
- 36 people
- Sponsor
- Carmel Medical Center
Adenoid Hypertrophy
Conventional Curettage Adenoidectomy vs Curettage Adenoidectomy With Transoral Endoscopic Residue Ablation in Children
This prospective study is designed to compare short and long term results of conventional cold curettage adenoidectomy in children performed without doing any endoscopic or mirror examination before ending the operation versus…
- Trial name
- NCT04302337
- Testing
- Curettage adenoidectomy with transoral endoscopic ablation, Conventional cold curettage adenoidectomy
- Where
- Turkey (Türkiye)
- Sponsor
- Istanbul University
Adenoid Hypertrophy, Middle Ear Effusion
It is Accepted That Adenoid Hypertrophy is Related to Otitis Media With Effusion Incidence. Better Understanding of the Correlation Between the Relative Size of AH and the Incidence of Persistent OME May Provide Evidence to Support a More Standardized Approach to the Diagnosis and Treatment of OME.
The aim of this study is to further investigate the correlation between Site and size of adenoid hypertrophy and middle ear effusion in order to provide evidence for designing a more standardized approach to the diagnosis and…
- Trial name
- NCT06674720
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Turbinate Hypertrophy, Adenoidectomy
Adenoidectomy With or Without Partial Inferior Turbinectomy for Pediatric Nasal Obstruction
Nasal obstruction is a common problem in children and is frequently caused by adenoid hypertrophy with concomitant inferior turbinate hypertrophy, leading to sleep-disordered breathing and reduced quality of life.
- Conditions
- Turbinate Hypertrophy, Adenoidectomy, Adenoid Hypertrophy, Turbinate Surgery
- Trial name
- NCT07745868
- Testing
- adenoidectomy, Adenodiectomy and bilateral partial infeiror turbienctomy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Al-Azhar University