Chronic Kidney DiseasePhase 3Elevate-CKDNCT07753993

A Study to Investigate Outcomes With Elecoglipron Compared With Placebo in Adult Participants With Chronic Kidney Disease.

A Phase 3 study testing Elecoglipron in people with Chronic Kidney Disease, run by AstraZeneca at 715 sites in 37 countries.

Recruiting

Looking for participants now. Contact the study team or a site below to ask about taking part.

Sites and contacts

Official record

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Trial summary

This is a Phase III, randomized, double-blind, parallel-group, placebo-controlled multicenter study to investigate outcomes with elecoglipron compared with placebo in participants with CKD with and without T2DM who are on background SGLT2i (dapagliflozin) as GDMT and other SoC treatments for CKD. Read more about this study

Who is it for?: Ages 18 years and older
Conditions the study is for: Chronic Kidney Disease
What is being tested?: Elecoglipron
Type of treatment: Pill or oral medicine
Could I receive a placebo?: Yes, some participants may receive a placebo
How many people: 7,000 participants
Where: 715 sitesin 37 countries
Study dates: 21 Aug 2026to 4 Oct 2030
Phase: Phase 3
Are there results?: Not yet: the study is under way

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

Ages 18 years and older
All sexes
No healthy volunteers
Adult, Older adult

Who may be able to join

Adults with confirmed CKD; UACR ≥30 mg/g and eGFR ≥20 mL/min/1.73 m² within specified ranges.
On stable, patient maximum tolerated, labeled daily dose of ACEI or ARB for ≥4 weeks at least 28 days before screening.

Who cannot join

BMI <23 kg/m² at screening
History of type 1 diabetes mellitus
HbA1c ≥10% (86 mmol/mol) at screening
Currently receiving, or anticipated to receive, therapeutic intervention for diabetic retinopathy and/or macular edema.
Have had more than one episode of severe hypoglycemia within 180 days prior to screening, or hypoglycemia unawareness
Acute coronary syndrome, major cardiac procedure, stroke, or TIA within 3 months prior to screening

Show all 9Show fewer

Clinically significant condition affecting the upper GI tract or chronic use of any medication that affects gastric motility or gastric emptying
History of acute or chronic pancreatitis
History/family history (first degree) of medullary thyroid cancer or MEN2

Trial locations and contacts

715 sites in 37 countries. Contact the study team or a site near you to ask about taking part.

AstraZeneca Clinical Study Information Center contact

1-877-240-9479

information.center@astrazeneca.com

Country

City, postcode or hospital

Sites recruiting now only

715 sites in 37 countries

United States120 sites, 111 recruiting

Research Site
Albany, New York, 12205
Not yet recruiting
Research Site
Albuquerque, New Mexico, 87106
Not yet recruiting
Research Site
Ames, Iowa, 50010
Withdrawn
Research Site
Arlington, Texas, 76015
Recruiting
Research Site
Arlington, Virginia, 22205
Not yet recruiting
Research Site
Arvada, Colorado, 80002
Not yet recruiting
Research Site
Austell, Georgia, 30106
Not yet recruiting
Research Site
Beaver, Pennsylvania, 15009
Not yet recruiting
Research Site
Beltsville, Maryland, 20705
Not yet recruiting
Research Site
Boca Raton, Florida, 33487
Not yet recruiting
Research Site
Boston, Massachusetts, 02115
Not yet recruiting
Research Site
Boynton Beach, Florida, 33435
Not yet recruiting
Research Site
Brookhaven, Mississippi, 39601
Not yet recruiting
Research Site
Brooklyn, New York, 11220
Not yet recruiting
Research Site
Buffalo, New York, 14215
Not yet recruiting
Research Site
Burlington, Vermont, 05401
Not yet recruiting
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Champaign, Illinois, 61820
Not yet recruiting
Research Site
Chesterfield, Missouri, 63005
Not yet recruiting
Research Site
Chicago, Illinois, 60611
Not yet recruiting
Research Site
Chicago, Illinois, 60640
Not yet recruiting
Research Site
Chula Vista, California, 91910
Not yet recruiting
Research Site
Cincinnati, Ohio, 45212
Not yet recruiting
Research Site
Columbus, Georgia, 31904
Not yet recruiting
Research Site
Concord, California, 94520
Not yet recruiting
Research Site
Cutler Bay, Florida, 33157
Not yet recruiting
Research Site
Dallas, Texas, 75246
Not yet recruiting
Research Site
Daly City, California, 94015
Not yet recruiting
Research Site
Denver, Colorado, 80220
Not yet recruiting
Research Site
Detroit, Michigan, 48207
Not yet recruiting
Research Site
East Point, Georgia, 30344
Not yet recruiting
Research Site
East Providence, Rhode Island, 02914
Not yet recruiting
Research Site
Eatontown, New Jersey, 07724
Not yet recruiting
Research Site
El Paso, Texas, 79902
Not yet recruiting
Research Site
Exton, Pennsylvania, 19341
Not yet recruiting
Research Site
Flint, Michigan, 48532
Not yet recruiting
Research Site
Fort Lauderdale, Florida, 33316
Not yet recruiting
Research Site
Fremont, California, 94538
Not yet recruiting
Research Site
Greensboro, North Carolina, 27405
Not yet recruiting
Research Site
Hartford, Connecticut, 06112
Not yet recruiting
Research Site
Hollywood, Florida, 33024
Not yet recruiting
Research Site
Houston, Texas, 77036
Not yet recruiting
Research Site
Houston, Texas, 77040
Not yet recruiting
Research Site
Houston, Texas, 77054
Not yet recruiting
Research Site
Huntington Beach, California, 92647
Not yet recruiting
Research Site
Huntington Park, California, 90255
Not yet recruiting
Research Site
Huntsville, Alabama, 35801
Not yet recruiting
Research Site
Indiana, Pennsylvania, 15701
Not yet recruiting
Research Site
Jacksonville Beach, Florida, 32250
Not yet recruiting
Research Site
Jensen Beach, Florida, 34957
Not yet recruiting
Research Site
Jersey City, New Jersey, 07306
Not yet recruiting
Research Site
Knoxville, Tennessee, 37912
Withdrawn
Research Site
Las Vegas, Nevada, 89101
Not yet recruiting
Research Site
Las Vegas, Nevada, 89107
Not yet recruiting
Research Site
Las Vegas, Nevada, 89146
Not yet recruiting
Research Site
Lauderdale Lakes, Florida, 33313
Not yet recruiting
Research Site
Little Rock, Arkansas, 72205
Withdrawn
Research Site
Lomita, California, 90717
Not yet recruiting
Research Site
Longwood, Florida, 32750
Not yet recruiting
Research Site
Lubbock, Texas, 79430
Not yet recruiting
Research Site
Maumee, Ohio, 43537
Not yet recruiting
Research Site
McKinney, Texas, 75071
Not yet recruiting
Research Site
Media, Pennsylvania, 19063
Not yet recruiting
Research Site
Melbourne, Florida, 32901
Not yet recruiting
Research Site
Mesquite, Texas, 75149
Not yet recruiting
Research Site
Miami, Florida, 33125
Not yet recruiting
Research Site
Miami, Florida, 33135
Not yet recruiting
Research Site
Middlebury, Connecticut, 06762
Not yet recruiting
Research Site
Mineola, New York, 11501
Not yet recruiting
Research Site
Minneapolis, Minnesota, 55435
Recruiting
Research Site
Minneapolis, Minnesota, 55435
Not yet recruiting
Research Site
Montgomery, Alabama, 36117
Not yet recruiting
Research Site
Morehead City, North Carolina, 28557
Not yet recruiting
Research Site
Morristown, Tennessee, 37813
Not yet recruiting
Research Site
National City, California, 91950
Not yet recruiting
Research Site
New Bedford, Massachusetts, 02740
Not yet recruiting
Research Site
Norfolk, Virginia, 23502
Not yet recruiting
Research Site
Northridge, California, 91324
Not yet recruiting
Research Site
Northridge, California, 91325
Not yet recruiting
Research Site
Ocoee, Florida, 34761
Not yet recruiting
Research Site
Orlando, Florida, 32806
Not yet recruiting
Research Site
Paris, Texas, 75462
Not yet recruiting
Research Site
Pasadena, Texas, 77504
Not yet recruiting
Research Site
Pensacola, Florida, 32503
Not yet recruiting
Research Site
Peoria, Arizona, 85382
Not yet recruiting
Research Site
Philadelphia, Pennsylvania, 19107
Not yet recruiting
Research Site
Phoenix, Arizona, 85012
Not yet recruiting
Research Site
Plymouth Meeting, Pennsylvania, 19462
Not yet recruiting
Research Site
Port Charlotte, Florida, 33952
Not yet recruiting
Research Site
Portland, Oregon, 97202
Not yet recruiting
Research Site
Providence, Rhode Island, 02903
Not yet recruiting
Research Site
Rapid City, South Dakota, 57701
Not yet recruiting
Research Site
Riverview, Florida, 33578
Not yet recruiting
Research Site
Rockford, Illinois, 61107
Not yet recruiting
Research Site
Rocky Mount, North Carolina, 27804
Suspended
Research Site
Rolling Hills Estates, California, 90274
Withdrawn
Research Site
Saginaw, Michigan, 48604
Not yet recruiting
Research Site
Saint Joseph, Michigan, 49085
Not yet recruiting
Research Site
San Antonio, Texas, 78212
Not yet recruiting
Research Site
San Antonio, Texas, 78230
Not yet recruiting
Research Site
San Antonio, Texas, 78251
Not yet recruiting
Research Site
San Diego, California, 92111
Not yet recruiting
Research Site
San Francisco, California, 94110
Withdrawn
Research Site
San Mateo, California, 94403
Not yet recruiting
Research Site
Seattle, Washington, 98122
Not yet recruiting
Research Site
Sheffield, Alabama, 35660
Not yet recruiting
Research Site
Shelby, North Carolina, 28150
Not yet recruiting
Research Site
Shenandoah, Texas, 77384
Not yet recruiting
Research Site
South Salt Lake, Utah, 84115
Recruiting
Research Site
Southfield, Michigan, 48075
Not yet recruiting
Research Site
Statesville, North Carolina, 28625
Suspended
Research Site
Sugar Land, Texas, 77479
Not yet recruiting
Research Site
Surprise, Arizona, 85374
Not yet recruiting
Research Site
Tarzana, California, 91356
Not yet recruiting
Research Site
Tinley Park, Illinois, 60477
Not yet recruiting
Research Site
Topeka, Kansas, 66606
Withdrawn
Research Site
Troy, Michigan, 48098
Not yet recruiting
Research Site
Tucker, Georgia, 30084
Not yet recruiting
Research Site
Waterbury, Connecticut, 06708
Not yet recruiting
Research Site
Wilmington, North Carolina, 28401
Suspended
Research Site
Wilmington, North Carolina, 28403
Not yet recruiting

Other trials in United States

China66 sites, 66 recruiting

Research Site
Baoding, 071000
Not yet recruiting
Research Site
Beijing, 100029
Not yet recruiting
Research Site
Beijing, 100034
Not yet recruiting
Research Site
Beijing, 100037
Not yet recruiting
Research Site
Beijing, 101199
Not yet recruiting
Research Site
Beijing, 102218
Not yet recruiting
Research Site
Changchun, 130021
Not yet recruiting
Research Site
Changsha, 410008
Not yet recruiting
Research Site
Changsha, 410015
Not yet recruiting
Research Site
Changzhou, 213000
Not yet recruiting
Research Site
Changzhou, 213100
Not yet recruiting
Research Site
Chengdu, 610041
Not yet recruiting
Research Site
Chenzhou, 423000
Not yet recruiting
Research Site
Chongqing, 400010
Not yet recruiting
Research Site
Dongguan, 523009
Not yet recruiting
Research Site
Foshan, 528000
Not yet recruiting
Research Site
Ganzhou, 341000
Not yet recruiting
Research Site
Guangzhou, 510100
Not yet recruiting
Research Site
Guangzhou, 510150
Not yet recruiting
Research Site
Guangzhou, 510280
Not yet recruiting
Research Site
Guangzhou, 510665
Not yet recruiting
Research Site
Guiyang, 550044
Not yet recruiting
Research Site
Hefei, 230061
Not yet recruiting
Research Site
Huangshi, 435000
Not yet recruiting
Research Site
Huizhou, 516001
Not yet recruiting
Research Site
Jiangmen, 529000
Not yet recruiting
Research Site
Jining, 272006
Not yet recruiting
Research Site
Linfen, 041099
Not yet recruiting
Research Site
Luoyang, 471003
Not yet recruiting
Research Site
Nanchang, 330006
Not yet recruiting
Research Site
Nanjing, 210011
Not yet recruiting
Research Site
Nanjing, 210029
Not yet recruiting
Research Site
Nanning, 530000
Not yet recruiting
Research Site
Nanning, 530021
Not yet recruiting
Research Site
Nanning, 530022
Not yet recruiting
Research Site
Ningbo, 315000
Not yet recruiting
Research Site
Panjin, 124009
Not yet recruiting
Research Site
Pingxiang, 337055
Not yet recruiting
Research Site
Qingzhou, 262550
Not yet recruiting
Research Site
Sacramento, 95816
Not yet recruiting
Research Site
Shanghai, 200001
Not yet recruiting
Research Site
Shanghai, 200240
Not yet recruiting
Research Site
Shanghai, 201199
Not yet recruiting
Research Site
Shantou, 515065
Not yet recruiting
Research Site
Shenzhen, 518020
Not yet recruiting
Research Site
Shenzhen, 518036
Not yet recruiting
Research Site
Shenzhen, 518039
Not yet recruiting
Research Site
Shenzhen, 518053
Not yet recruiting
Research Site
Shijiazhuang, 50051
Not yet recruiting
Research Site
Tianjin, 300000
Not yet recruiting
Research Site
Tianjin, CN-300052
Not yet recruiting
Research Site
Ürümqi, 831118
Not yet recruiting
Research Site
Wuhan, 430010
Not yet recruiting
Research Site
Wuhan, 430033
Not yet recruiting
Research Site
Wuhan, 430060
Not yet recruiting
Research Site
Wuxi, 214023
Not yet recruiting
Research Site
Xi'an, 710068
Not yet recruiting
Research Site
Xuzhou, 221000
Not yet recruiting
Research Site
Yancheng, 224005
Not yet recruiting
Research Site
Yangzhou, 225000
Not yet recruiting
Research Site
Yantai, 264000
Not yet recruiting
Research Site
Yibin, 644000
Not yet recruiting
Research Site
Zhenjiang, 212002
Not yet recruiting
Research Site
Zhongshan, 528401
Not yet recruiting
Research Site
Zigong, 643000
Not yet recruiting
Research Site
Zunyi, 563100
Not yet recruiting

Other trials in China

Japan57 sites, 54 recruiting

Research Site
Aira, 899-5421
Not yet recruiting
Research Site
Akita, 010-8543
Not yet recruiting
Research Site
Asahikawa-shi, 070-8530
Not yet recruiting
Research Site
Chūōku, 103-0002
Not yet recruiting
Research Site
Fujisawa-shi, 251-0041
Not yet recruiting
Research Site
Fukuoka, 814-0180
Not yet recruiting
Research Site
Fukuoka, 815-0033
Not yet recruiting
Research Site
Hachioji-shi, 192-0083
Not yet recruiting
Research Site
Hamamatsu, 431-3192
Not yet recruiting
Research Site
Hiroshima, 734-8551
Not yet recruiting
Research Site
Ichikawa-shi, 272-8516
Not yet recruiting
Research Site
Ina-shi, 396-8555
Not yet recruiting
Research Site
Iruma-Gun, 350-0495
Not yet recruiting
Research Site
Izunokuni-shi, 410-2295
Not yet recruiting
Research Site
Kamakura-shi, 247-0056
Recruiting
Research Site
Kamiina-gun, 399-4511
Not yet recruiting
Research Site
Kanazawa, 920-8650
Not yet recruiting
Research Site
Kasuga-shi, 816-0864
Withdrawn
Research Site
Kasugai-shi, 486-8510
Not yet recruiting
Research Site
Kawachinagano-shi, 586-8521
Not yet recruiting
Research Site
Kitakyushu, 802-8555
Not yet recruiting
Research Site
Kitakyushu-shi, 802-0077
Not yet recruiting
Research Site
Kumamoto, 862-0950
Withdrawn
Research Site
Kurume, 830-8543
Not yet recruiting
Research Site
Kuwana-shi, 511-0061
Not yet recruiting
Research Site
Matsumoto-shi, 390-1401
Not yet recruiting
Research Site
Minatoku, 108-0073
Not yet recruiting
Research Site
Minokamo Shi, 505-8510
Recruiting
Research Site
Moriyama-shi, 524-8524
Not yet recruiting
Research Site
Nagoya, 451-8511
Not yet recruiting
Research Site
Nagoya, 468-0009
Recruiting
Research Site
Naka, 311-0113
Not yet recruiting
Research Site
Naka, 311-0133
Not yet recruiting
Research Site
Ōita, 870-0039
Not yet recruiting
Research Site
Okayama, 700-0804
Not yet recruiting
Research Site
Okayama, 700-8557
Not yet recruiting
Research Site
Osaka, 558-8558
Not yet recruiting
Research Site
Osaka, 559-0012
Not yet recruiting
Research Site
Oyama-shi, 323-0022
Not yet recruiting
Research Site
Sakaishi, 593-8304
Not yet recruiting
Research Site
Sakushu, 385-8558
Not yet recruiting
Research Site
Sapporo, 006-0852
Not yet recruiting
Research Site
Sapporo, 060-0062
Not yet recruiting
Research Site
Sapporo, 062-0931
Not yet recruiting
Research Site
Sasebo-shi, 857-8511
Withdrawn
Research Site
Shinjuku-ku, 160-0023
Not yet recruiting
Research Site
Suita-shi, 564-8565
Not yet recruiting
Research Site
Suita-shi, 565-0871
Not yet recruiting
Research Site
Suwa-shi, 392-8510
Not yet recruiting
Research Site
Takasago-shi, 676-0812
Not yet recruiting
Research Site
Tsu, 514-8507
Not yet recruiting
Research Site
Ueda-shi, 386-8610
Not yet recruiting
Research Site
Ushiku-shi, 300-1207
Not yet recruiting
Research Site
Utsunomiya, 321-0151
Not yet recruiting
Research Site
Yokohama, 230-8765
Not yet recruiting
Research Site
Yokohama, 234-0054
Not yet recruiting
Research Site
Yokohama, 236-0004
Not yet recruiting

Other trials in Japan

Germany49 sites, 41 recruiting

Research Site
Ahrensburg, 22926
Not yet recruiting
Research Site
Bad Mergentheim, 97980
Not yet recruiting
Research Site
Bad Nenndorf, 31542
Not yet recruiting
Research Site
Berlin, 10117
Not yet recruiting
Research Site
Berlin, 10249
Not yet recruiting
Research Site
Berlin, 10787
Not yet recruiting
Research Site
Berlin, 12203
Withdrawn
Research Site
Bonn, 53127
Withdrawn
Research Site
Brandenburg an der Havel, 14770
Not yet recruiting
Research Site
Braunschweig, 38126
Not yet recruiting
Research Site
Chemnitz, 09116
Not yet recruiting
Research Site
Cloppenburg, 49661
Not yet recruiting
Research Site
Cuxhaven, 27472
Withdrawn
Research Site
Dortmund, 44137
Not yet recruiting
Research Site
Dresden, 1307
Not yet recruiting
Research Site
Duisburg, 47269
Not yet recruiting
Research Site
Erlangen, 91054
Not yet recruiting
Research Site
Essen, 45122
Not yet recruiting
Research Site
Frankfurt, 60596
Not yet recruiting
Research Site
Frankfurt am Main, 60431
Not yet recruiting
Research Site
Freiburg im Breisgau, 79110
Not yet recruiting
Research Site
Fulda, 36037
Not yet recruiting
Research Site
Gladbeck, 45968
Not yet recruiting
Research Site
Goslar, 38642
Not yet recruiting
Research Site
Göttingen, 37075
Not yet recruiting
Research Site
Hamburg, 21109
Suspended
Research Site
Hamburg, 22041
Withdrawn
Research Site
Hamburg, 22143
Not yet recruiting
Research Site
Hanover, 30159
Suspended
Research Site
Hanover, 30625
Not yet recruiting
Research Site
Heidelberg, 69120
Not yet recruiting
Research Site
Herne, 44625
Not yet recruiting
Research Site
Jerichow, 39319
Withdrawn
Research Site
Kiel, 24105
Not yet recruiting
Research Site
Landshut, 84034
Not yet recruiting
Research Site
Leipzig, 04177
Not yet recruiting
Research Site
Leipzig, 04179
Not yet recruiting
Research Site
Lübeck, 23552
Not yet recruiting
Research Site
Magdeburg, 39120
Not yet recruiting
Research Site
Mannheim, 68167
Not yet recruiting
Research Site
Nuremberg, 90443
Not yet recruiting
Research Site
Nuremberg, 90471
Not yet recruiting
Research Site
Reinfeld (Holstein), 23858
Not yet recruiting
Research Site
Riesa, 01589
Not yet recruiting
Research Site
Rostock, 18057
Suspended
Research Site
Stuttgart, 70376
Recruiting
Research Site
Ulm, 89081
Not yet recruiting
Research Site
Wiesbaden, 65189
Not yet recruiting
Research Site
Würzburg, 97080
Not yet recruiting

Other trials in Germany

India24 sites, 24 recruiting

Research Site
Aligarh, 202002
Not yet recruiting
Research Site
Bangalore, 560060
Not yet recruiting
Research Site
Bangalore, 560092
Not yet recruiting
Research Site
Belagavi, 590006
Not yet recruiting
Research Site
Bhubaneswar, 751019
Not yet recruiting
Research Site
Calicut, 673 008
Not yet recruiting
Research Site
Chennai, 600037
Not yet recruiting
Research Site
Dehradun, 248001
Not yet recruiting
Research Site
Delhi, 110062
Not yet recruiting
Research Site
Gūrgaon, 122001
Not yet recruiting
Research Site
Guwahati, 781032
Not yet recruiting
Research Site
Haryāna, 124001
Not yet recruiting
Research Site
Hyderabad, 500028
Not yet recruiting
Research Site
Hyderabad, 500082
Not yet recruiting
Research Site
Kolkata, 700014
Not yet recruiting
Research Site
Kottayam, 686008
Not yet recruiting
Research Site
Mumbai, 400012
Not yet recruiting
Research Site
Mysuru, 570004
Not yet recruiting
Research Site
New Delhi, 110001
Not yet recruiting
Research Site
New Delhi, 110017
Not yet recruiting
Research Site
New Delhi, 110029
Not yet recruiting
Research Site
Noida, 201310
Not yet recruiting
Research Site
Secunderabad, 500003
Not yet recruiting
Research Site
Varanasi, 221 005
Not yet recruiting

Other trials in India

Brazil20 sites, 20 recruiting

Research Site
Barretos, 14784-400
Not yet recruiting
Research Site
Belém, 66073-005
Not yet recruiting
Research Site
Belo Horizonte, 30150-320
Not yet recruiting
Research Site
Bragança Paulista, 12916-542
Not yet recruiting
Research Site
Brasília, 71625-009
Not yet recruiting
Research Site
Campina Grande do Sul, 83.430-000
Not yet recruiting
Research Site
Campinas, 13060-080
Not yet recruiting
Research Site
Campinas, 13092133
Not yet recruiting
Research Site
Curitiba, 80810-040
Not yet recruiting
Research Site
Joinville, 89227-680
Not yet recruiting
Research Site
Natal, 59020-035
Not yet recruiting
Research Site
Porto Alegre, 90020-090
Not yet recruiting
Research Site
Porto Alegre, 9061-000
Not yet recruiting
Research Site
Porto Alegre, 90630-165
Not yet recruiting
Research Site
Presidente Prudente, 19050-680
Not yet recruiting
Research Site
São José dos Campos, 12230-001
Not yet recruiting
Research Site
São Paulo, 01228-000
Not yet recruiting
Research Site
São Paulo, 01327-001
Not yet recruiting
Research Site
São Paulo, 04038-031
Not yet recruiting
Research Site
São Paulo, 05403-9000
Not yet recruiting

Other trials in Brazil

Canada19 sites, 19 recruiting

Research Site
Calgary, Alberta, T2R0X7
Not yet recruiting
Research Site
Calgary, Alberta, T3R 1W9
Not yet recruiting
Research Site
Edmonton, Alberta, T6G 2B7
Not yet recruiting
Research Site
London, Ontario, N6A 5A5
Not yet recruiting
Research Site
London, Ontario, N6A 5W9
Not yet recruiting
Research Site
Montreal, Quebec, H1T 2M4
Not yet recruiting
Research Site
Montreal, Quebec, H2X 0A9
Not yet recruiting
Research Site
Montreal, Quebec, H3G 1A4
Not yet recruiting
Research Site
Montreal, Quebec, H4J 1C5
Not yet recruiting
Research Site
Saint John, New Brunswick, E2L 4L2
Not yet recruiting
Research Site
Scarborough Village, Ontario, M1H 3G4
Not yet recruiting
Research Site
Sherbrooke, Quebec, J1H 5N4
Not yet recruiting
Research Site
Toronto, Ontario, M4G 3E8
Recruiting
Research Site
Toronto, Ontario, M5B 1W8
Not yet recruiting
Research Site
Toronto, Ontario, M5G 2N2
Not yet recruiting
Research Site
Toronto, Ontario, M6G 1M2
Not yet recruiting
Research Site
Vancouver, British Columbia, V5Y 3W2
Not yet recruiting
Research Site
Waterloo, Ontario, N2T 0C1
Recruiting
Research Site
Winnipeg, Manitoba, R2V 3M3
Not yet recruiting

Other trials in Canada

Italy18 sites, 18 recruiting

Research Site
Alessandria, 15100
Not yet recruiting
Research Site
Bari, 70124
Not yet recruiting
Research Site
Bologna, 40138
Not yet recruiting
Research Site
Catania, 95125
Not yet recruiting
Research Site
Chieri, 10023
Not yet recruiting
Research Site
Cinisello Balsamo, 20092
Not yet recruiting
Research Site
Cosenza, 87100
Not yet recruiting
Research Site
Eboli, 84025
Not yet recruiting
Research Site
Feltre, 32032
Not yet recruiting
Research Site
Foggia, 71100
Not yet recruiting
Research Site
Naples, 80131
Not yet recruiting
Research Site
Pavia, 27100
Not yet recruiting
Research Site
Pordenone, 33170
Not yet recruiting
Research Site
Ranica, 24020
Not yet recruiting
Research Site
Rome, 00189
Not yet recruiting
Research Site
San Fermo della Battaglia, 22020
Not yet recruiting
Research Site
San Giovanni Rotondo, 71013
Not yet recruiting
Research Site
Trieste, 34149
Not yet recruiting

Other trials in Italy

Poland18 sites, 17 recruiting

Research Site
Będzin, 42-500
Not yet recruiting
Research Site
Bialystok, 15-481
Not yet recruiting
Research Site
Czeladź, 41-250
Not yet recruiting
Research Site
Gmina Świecie, 86-100
Not yet recruiting
Research Site
Katowice, 40-648
Not yet recruiting
Research Site
Kwidzyn, 82-500
Not yet recruiting
Research Site
Lodz, 92-213
Not yet recruiting
Research Site
Lublin, 20-011
Not yet recruiting
Research Site
Olsztyn, 10-117
Not yet recruiting
Research Site
Olsztyn, 10-561
Not yet recruiting
Research Site
Poznan, 60-355
Not yet recruiting
Research Site
Poznan, 61-251
Suspended
Research Site
Rzeszów, 35-205
Not yet recruiting
Research Site
Tczew, 83-110
Not yet recruiting
Research Site
Warsaw, 00-719
Not yet recruiting
Research Site
Warsaw, 04-141
Not yet recruiting
Research Site
Włocławek, 87-800
Not yet recruiting
Research Site
Żywiec, 34-300
Not yet recruiting

Other trials in Poland

United Kingdom18 sites, 18 recruiting

Research Site
Aberdeen, AB25 2ZN
Not yet recruiting
Research Site
Cardiff, CF14 4XW
Not yet recruiting
Research Site
Corby, NN18 9EZ
Not yet recruiting
Research Site
Coventry, CV3 4FJ
Not yet recruiting
Research Site
Dundee, DD1 9SY
Not yet recruiting
Research Site
Glasgow, G51 4TF
Not yet recruiting
Research Site
Leicester, LE9 7RT
Not yet recruiting
Research Site
Liverpool, L9 7AL
Not yet recruiting
Research Site
London, E1 1FR
Recruiting
Research Site
London, SE5 9RS
Not yet recruiting
Research Site
Metropolitan Borough of Wirral, CH48 5AA
Not yet recruiting
Research Site
Northwood, HA6 2RN
Not yet recruiting
Research Site
Nottingham, NG7 2QW
Not yet recruiting
Research Site
Portsmouth, PO6 3LY
Not yet recruiting
Research Site
Shipley, BD18 3SA
Not yet recruiting
Research Site
Swansea, SN6 6NL
Not yet recruiting
Research Site
Thetford, IP24 1JD
Not yet recruiting
Research Site
York, YO21 8HE
Not yet recruiting

Other trials in United Kingdom

Norway17 sites, 17 recruiting

Research Site
Bergen, 5021
Not yet recruiting
Research Site
Bodø, 8005
Not yet recruiting
Research Site
Drammen, 3004
Not yet recruiting
Research Site
Grålum, 1714
Not yet recruiting
Research Site
Haugesund, 5528
Not yet recruiting
Research Site
Levanger, 7601
Not yet recruiting
Research Site
Lørenskog, 1478
Not yet recruiting
Research Site
Oslo, 0369
Not yet recruiting
Research Site
Oslo, 0450
Not yet recruiting
Research Site
Oslo, 0456
Not yet recruiting
Research Site
Oslo, 0586
Not yet recruiting
Research Site
Skedsmokorset, N-2020
Not yet recruiting
Research Site
Skien, 3710
Not yet recruiting
Research Site
Stavanger, N-4011
Not yet recruiting
Research Site
Tønsberg, 3116
Not yet recruiting
Research Site
Tromsø, N-9038
Not yet recruiting
Research Site
Trondheim, 7006
Not yet recruiting

Other trials in Norway

Malaysia16 sites, 16 recruiting

Research Site
Ipoh, 30990
Not yet recruiting
Research Site
Kajang, 43000
Not yet recruiting
Research Site
Klang, 41200
Not yet recruiting
Research Site
Kota Bharu, 15586
Not yet recruiting
Research Site
Kota Kinabalu, 88200
Not yet recruiting
Research Site
Kuala Lumpur, 50450
Not yet recruiting
Research Site
Kuala Lumpur, 50586
Not yet recruiting
Research Site
Kuala Lumpur, 56000
Not yet recruiting
Research Site
Kuala Lumpur, 59100
Not yet recruiting
Research Site
Kuala Pilah, 72000
Not yet recruiting
Research Site
Petaling Jaya, 47500
Not yet recruiting
Research Site
Sarawak Miri, 98000
Not yet recruiting
Research Site
Seri Manjung, 32040
Not yet recruiting
Research Site
Sibu, 96000
Not yet recruiting
Research Site
Sungai Buloh, 47000
Not yet recruiting
Research Site
Taiping, 34000
Not yet recruiting

Other trials in Malaysia

Taiwan16 sites, 16 recruiting

Research Site
Changhua, 500
Not yet recruiting
Research Site
Kaohsiung City, 81362
Not yet recruiting
Research Site
Kaohsiung City, 833
Not yet recruiting
Research Site
New Taipei City, 220
Not yet recruiting
Research Site
New Taipei City, 23561
Not yet recruiting
Research Site
Taichung, 402
Not yet recruiting
Research Site
Taichung, 40447
Not yet recruiting
Research Site
Taichung, 407219
Not yet recruiting
Research Site
Taichung, 433004
Recruiting
Research Site
Tainan, 704
Not yet recruiting
Research Site
Tainan, 73657
Not yet recruiting
Research Site
Taipei, 10002
Recruiting
Research Site
Taipei, 110
Not yet recruiting
Research Site
Taipei, 11696
Not yet recruiting
Research Site
Taoyuan, 333
Not yet recruiting
Research Site
Yung Kang City, 71044
Not yet recruiting

Other trials in Taiwan

Argentina14 sites, 13 recruiting

Research Site
Buenos Aires, C1056
Not yet recruiting
Research Site
Buenos Aires, C1060AAB
Not yet recruiting
Research Site
Caba, C1128AAF
Not yet recruiting
Research Site
CABA, C1425HFA
Not yet recruiting
Research Site
Ciudad de Buenos Aires, 1128
Not yet recruiting
Research Site
Ciudad de Buenos Aires, C1094AAD
Not yet recruiting
Research Site
Córdoba, X5006CBI
Not yet recruiting
Research Site
La Plata, B1900
Withdrawn
Research Site
Mar del Plata, 7600
Not yet recruiting
Research Site
Mar del Plata, B7600
Not yet recruiting
Research Site
Rosario, 2000
Not yet recruiting
Research Site
Rosario, S2000CVD
Not yet recruiting
Research Site
San Nicolás, B2900DMH
Not yet recruiting
Research Site
Santa Rosa, 6300
Not yet recruiting

Other trials in Argentina

Czechia14 sites, 12 recruiting

Research Site
Hradec Králové, 50005
Not yet recruiting
Research Site
Humpolec, 396 01
Withdrawn
Research Site
Jilemnice, 514 01
Not yet recruiting
Research Site
Liberec, 46014
Not yet recruiting
Research Site
Mariánské Lázně, 35301
Not yet recruiting
Research Site
Náchod, 547 01
Not yet recruiting
Research Site
Nové Město na Moravě, 692 31
Not yet recruiting
Research Site
Nový Jičín, 741 01
Not yet recruiting
Research Site
Ostrava, 70030
Not yet recruiting
Research Site
Prague, 100 34
Not yet recruiting
Research Site
Prague, 130 00
Not yet recruiting
Research Site
Prague, 160 00
Not yet recruiting
Research Site
Tábor, 390 03
Not yet recruiting
Research Site
Třebíč, 674 01
Withdrawn

Other trials in Czechia

France14 sites, 14 recruiting

Research Site
Corbeil-Essonnes, 91100
Not yet recruiting
Research Site
Grenoble, 38043
Not yet recruiting
Research Site
La Rochelle, 17000
Not yet recruiting
Research Site
Laval, 53015
Not yet recruiting
Research Site
Le Puy-en-Velay, 43000
Not yet recruiting
Research Site
Lyon, 69007
Not yet recruiting
Research Site
Lyon, 69437
Not yet recruiting
Research Site
Metz-Tessy, 74370
Not yet recruiting
Research Site
Montpellier, 34090
Not yet recruiting
Research Site
Orléans, 45067
Not yet recruiting
Research Site
Pessac, 33604
Not yet recruiting
Research Site
Saint-Herblain, 44800
Not yet recruiting
Research Site
Saint-Priest-en-Jarez, 42270
Not yet recruiting
Research Site
Valenciennes, 59322
Not yet recruiting

Other trials in France

Indonesia14 sites, 14 recruiting

Research Site
Daerah Khusus Ibukota, 12430
Not yet recruiting
Research Site
Denpasar, 80361
Not yet recruiting
Research Site
Ibukota, 12430
Not yet recruiting
Research Site
Jakarta, 10430
Not yet recruiting
Research Site
Jakarta, 11530
Not yet recruiting
Research Site
Kabupaten Sukoharjo, 57161
Not yet recruiting
Research Site
Kota Padang, 25171
Not yet recruiting
Research Site
Medan, 20136
Not yet recruiting
Research Site
Semarang, 50244
Not yet recruiting
Research Site
Surabaya, 60281
Not yet recruiting
Research Site
Tangerang, 15117
Not yet recruiting
Research Site
Tangerang, 15811
Not yet recruiting
Research Site
Tj. Merdeka, 90112
Not yet recruiting
Research Site
Yogyakarta, 55281
Not yet recruiting

Other trials in Indonesia

Peru14 sites, 14 recruiting

Research Site
Bellavista, CALLAO 2
Not yet recruiting
Research Site
Callao, Bellavista
Not yet recruiting
Research Site
Chorrillos, Lima 9
Not yet recruiting
Research Site
Cusco, CUSCO 01
Not yet recruiting
Research Site
Lima, 14
Not yet recruiting
Research Site
Lima, 15038
Not yet recruiting
Research Site
Lima, 15046
Not yet recruiting
Research Site
Lima, 15072
Not yet recruiting
Research Site
Lima, 15082
Not yet recruiting
Research Site
Lima, 15088
Not yet recruiting
Research Site
Lima, LIMA 01
Not yet recruiting
Research Site
Lima, LIMA 27
Not yet recruiting
Research Site
Piura, 20001
Not yet recruiting
Research Site
Piura, 20009
Not yet recruiting

Other trials in Peru

Romania14 sites, 14 recruiting

Research Site
Bucharest, 010507
Not yet recruiting
Research Site
Bucharest, 011053
Not yet recruiting
Research Site
Bucharest, 031141
Not yet recruiting
Research Site
Bucharest, 060044
Not yet recruiting
Research Site
Bucharest, 22328
Not yet recruiting
Research Site
Cluj-Napoca, 400349
Not yet recruiting
Research Site
Iași, 700515
Not yet recruiting
Research Site
Oradea, 410001
Not yet recruiting
Research Site
Oradea, 410032
Not yet recruiting
Research Site
Oradea, 410469
Not yet recruiting
Research Site
Oradea, 410562
Not yet recruiting
Research Site
Ploieşti, 100179
Not yet recruiting
Research Site
Timișoara, 300723
Not yet recruiting
Research Site
Timișoara, 300736
Not yet recruiting

Other trials in Romania

South Korea14 sites, 14 recruiting

Research Site
Anyang-si, 14068
Not yet recruiting
Research Site
Busan, 48108
Not yet recruiting
Research Site
Busan, 49241
Not yet recruiting
Research Site
Cheonan-si, 31151
Not yet recruiting
Research Site
Daejeon, 34943
Not yet recruiting
Research Site
Goyang-si, 10380
Not yet recruiting
Research Site
Guri-si, 11923
Not yet recruiting
Research Site
Junggu, 41944
Not yet recruiting
Research Site
Seoul, 03080
Not yet recruiting
Research Site
Seoul, 03722
Not yet recruiting
Research Site
Seoul, 04401
Not yet recruiting
Research Site
Seoul, 06591
Not yet recruiting
Research Site
Seoul, 08308
Not yet recruiting
Research Site
Seoul, 5505
Not yet recruiting

Other trials in South Korea

Thailand14 sites, 14 recruiting

Research Site
Bangkok, 10210
Not yet recruiting
Research Site
Bangkok, 10220
Not yet recruiting
Research Site
Bangkok, 10300
Not yet recruiting
Research Site
Bangkok, 10330
Not yet recruiting
Research Site
Bangkok, 10400
Not yet recruiting
Research Site
Bangkok, 10700
Not yet recruiting
Research Site
Banphaeo, 74120
Not yet recruiting
Research Site
Hat Yai, 90110
Not yet recruiting
Research Site
Khlong Luang, 12120
Not yet recruiting
Research Site
Muang, 50200
Not yet recruiting
Research Site
Phitsanulok, 65000
Not yet recruiting
Research Site
Phutthamonthon, 73170
Not yet recruiting
Research Site
Ratchaburi, 70000
Not yet recruiting
Research Site
Ubonratchathani, 34000
Not yet recruiting

Other trials in Thailand

Vietnam13 sites, 11 recruiting

Research Site
Can Tho, 900000
Not yet recruiting
Research Site
Da Nang, 55000
Not yet recruiting
Research Site
Hà Nội, 100000
Not yet recruiting
Research Site
Haiphong, 180000
Not yet recruiting
Research Site
Hanoi, 100000
Not yet recruiting
Research Site
Hanoi, 100000
Withdrawn
Research Site
Hanoi, 10000
Not yet recruiting
Research Site
Hồ Chí Minh, 700000
Not yet recruiting
Research Site
Ho Chi Minh City, 7000000
Not yet recruiting
Research Site
Ho Chi Minh City, 700000
Not yet recruiting
Research Site
Ho Chi Minh City, 700000
Suspended
Research Site
Ho Chi Minh City, 70000
Not yet recruiting
Research Site
Hochiminh City, 700000
Not yet recruiting

Other trials in Vietnam

Greece12 sites, 11 recruiting

Research Site
Alexandroupoli, 68100
Not yet recruiting
Research Site
Athens, 11527
Not yet recruiting
Research Site
Athens, 12462
Not yet recruiting
Research Site
Athens, 15125
Not yet recruiting
Research Site
Chios, 82100
Not yet recruiting
Research Site
Heraklion, 71500
Not yet recruiting
Research Site
Ioannina, 45500
Not yet recruiting
Research Site
Larissa, 41500
Not yet recruiting
Research Site
Pátrai, 26504
Not yet recruiting
Research Site
Thessaloniki, 54642
Suspended
Research Site
Thessaloniki, 54645
Not yet recruiting
Research Site
Thessaloniki, 57001
Not yet recruiting

Other trials in Greece

Spain12 sites, 12 recruiting

Research Site
Badajoz, 06080
Not yet recruiting
Research Site
Barcelona, 08035
Not yet recruiting
Research Site
Barcelona, 08036
Not yet recruiting
Research Site
Burgos, 09006
Not yet recruiting
Research Site
Córdoba, 14004
Not yet recruiting
Research Site
Granada, 18014
Not yet recruiting
Research Site
Madrid, 28041
Not yet recruiting
Research Site
Majadahonda, 28222
Not yet recruiting
Research Site
Málaga, 29010
Not yet recruiting
Research Site
Pamplona, 31008
Not yet recruiting
Research Site
Valencia, 46010
Not yet recruiting
Research Site
Valencia, 46026
Not yet recruiting

Other trials in Spain

Bulgaria11 sites, 11 recruiting

Research Site
Botevgrad, 2140
Not yet recruiting
Research Site
Byala Slatina, 3200
Not yet recruiting
Research Site
Pleven, 5800
Not yet recruiting
Research Site
Plovdiv, 4000
Not yet recruiting
Research Site
Plovdiv, 4001
Not yet recruiting
Research Site
Plovdiv, 4004
Not yet recruiting
Research Site
Sofia, 1407
Not yet recruiting
Research Site
Sofia, 1756
Not yet recruiting
Research Site
Varna, 9000
Not yet recruiting
Research Site
Varna, 9010
Not yet recruiting
Research Site
Yambol, 8600
Not yet recruiting

Other trials in Bulgaria

Ukraine11 sites, 11 recruiting

Research Site
Ivano-Frankivsk, 76018
Not yet recruiting
Research Site
Kyiv, 01601
Not yet recruiting
Research Site
Kyiv, 02002
Not yet recruiting
Research Site
Kyiv, 03037
Not yet recruiting
Research Site
Kyiv, 03049
Not yet recruiting
Research Site
Kyiv, 03057
Not yet recruiting
Research Site
Kyiv, 04114
Not yet recruiting
Research Site
Kyiv, 04210
Not yet recruiting
Research Site
Lviv, 79016
Not yet recruiting
Research Site
Vinnytsia, 21001
Not yet recruiting
Research Site
Vinnytsia, 21029
Not yet recruiting

Other trials in Ukraine

Hungary10 sites, 10 recruiting

Research Site
Budapest, 1033
Not yet recruiting
Research Site
Budapest, 1085
Not yet recruiting
Research Site
Budapest, 1138
Not yet recruiting
Research Site
Gyula, 5700
Not yet recruiting
Research Site
Hatvan, 3000
Not yet recruiting
Research Site
Kalocsa, 6300
Not yet recruiting
Research Site
Nagykanizsa, 8800
Not yet recruiting
Research Site
Nyíregyháza, 4400
Not yet recruiting
Research Site
Szeged, 6725
Not yet recruiting
Research Site
Szigetvár, 7900
Not yet recruiting

Other trials in Hungary

Israel10 sites, 10 recruiting

Research Site
Ashkelon, 78278
Not yet recruiting
Research Site
Be’er Ya‘aqov, 70300
Not yet recruiting
Research Site
Hadera, 38100
Not yet recruiting
Research Site
Haifa, 34362
Not yet recruiting
Research Site
Holon, 58100
Not yet recruiting
Research Site
Kfar Saba, 4428164
Not yet recruiting
Research Site
Nahariya, 22100
Not yet recruiting
Research Site
Ramat Gan, 52621
Not yet recruiting
Research Site
Rehovot, 76100
Not yet recruiting
Research Site
Tiberias, 15208
Not yet recruiting

Other trials in Israel

Sweden10 sites, 10 recruiting

Research Site
Falun, 79182
Not yet recruiting
Research Site
Gothenburg, 41345
Not yet recruiting
Research Site
Karlstad, 651 85
Not yet recruiting
Research Site
Linköping, 581 85
Not yet recruiting
Research Site
Lund, 221 85
Not yet recruiting
Research Site
Örebro, 70185
Not yet recruiting
Research Site
Stockholm, 141 86
Not yet recruiting
Research Site
Stockholm, SE-18288
Not yet recruiting
Research Site
Uppsala, 75185
Not yet recruiting
Research Site
Vaxjo, 352 34
Not yet recruiting

Other trials in Sweden

Australia9 sites, 9 recruiting

Research Site
Castle Hill, 2154
Not yet recruiting
Research Site
Fitzroy, 3065
Not yet recruiting
Research Site
Gosford, 2250
Recruiting
Research Site
Melbourne, 3004
Not yet recruiting
Research Site
Perth, 6000
Not yet recruiting
Research Site
Southport, 4215
Recruiting
Research Site
St Leonards, 2065
Not yet recruiting
Research Site
Wollongong, 2500
Not yet recruiting
Research Site
Woolloongabba, 4102
Not yet recruiting

Other trials in Australia

Chile9 sites, 9 recruiting

Research Site
Araucania, 4781151
Not yet recruiting
Research Site
Osorno, 5311092
Not yet recruiting
Research Site
Region Metropolitana, 7550000
Not yet recruiting
Research Site
Santiago, 7510187
Not yet recruiting
Research Site
Santiago, 8330034
Not yet recruiting
Research Site
Santiago
Not yet recruiting
Research Site
Temuco, 4810345
Not yet recruiting
Research Site
Victoria, 4720000
Not yet recruiting
Research Site
Viña del Mar, 2540488
Not yet recruiting

Other trials in Chile

Philippines9 sites, 9 recruiting

Research Site
Davao City, 8000
Not yet recruiting
Research Site
Davao City, PH-8000
Not yet recruiting
Research Site
Iloilo City, 5000
Not yet recruiting
Research Site
Las Piñas, 1742
Not yet recruiting
Research Site
Manadaluyong City, 1552
Not yet recruiting
Research Site
Pasig, 1605
Not yet recruiting
Research Site
Quezon City, 0870
Not yet recruiting
Research Site
Quezon City, 1101
Not yet recruiting
Research Site
Quezon City, 1112
Not yet recruiting

Other trials in Philippines

Denmark7 sites, 7 recruiting

Research Site
Aalborg, 9000
Not yet recruiting
Research Site
Aarhus, 8200
Not yet recruiting
Research Site
Copenhagen E, 2100
Not yet recruiting
Research Site
Herlev, 2730
Not yet recruiting
Research Site
Herning, 7400
Not yet recruiting
Research Site
Holbæk, 4300
Not yet recruiting
Research Site
Roskilde, 4000
Not yet recruiting

Other trials in Denmark

Mexico7 sites, 7 recruiting

Research Site
Chihuahua City, 31238
Not yet recruiting
Research Site
Culiacán, 80230
Not yet recruiting
Research Site
Mazatlán, 82000
Not yet recruiting
Research Site
Mérida, 97070
Not yet recruiting
Research Site
Mérida, 97130
Not yet recruiting
Research Site
Monterrey, 64060
Not yet recruiting
Research Site
Zapopan, 45070
Not yet recruiting

Other trials in Mexico

Serbia7 sites, 7 recruiting

Research Site
Belgrade, 11000
Not yet recruiting
Research Site
Belgrade, 11070
Not yet recruiting
Research Site
Belgrade, 11080
Not yet recruiting
Research Site
Kragujevac, 34000
Not yet recruiting
Research Site
Kruševac, 37000
Not yet recruiting
Research Site
Niš, 18000
Not yet recruiting
Research Site
Pančevo, 26101
Not yet recruiting

Other trials in Serbia

Finland6 sites, 6 recruiting

Research Site
Helsinki, 00290
Not yet recruiting
Research Site
Jyväskylä, 40620
Not yet recruiting
Research Site
Oulu, 90220
Not yet recruiting
Research Site
Tampere, 33100
Not yet recruiting
Research Site
Tampere, 33101
Not yet recruiting
Research Site
Turku, 20100
Not yet recruiting

Other trials in Finland

United Arab Emirates2 sites, 2 recruiting

Research Site
Abu Dhabi, 48338
Not yet recruiting
Research Site
Abu Dhabi, 48481
Not yet recruiting

Other trials in United Arab Emirates

About this study

Official title: A Phase III, Randomized, Double-blind, Parallel-group, Placebo-controlled Multicenter Study to Evaluate the Effect of Elecoglipron in Reducing Renal Outcomes and Mortality in Participants With Chronic Kidney Disease (Elevate-CKD)

Conditions: Chronic Kidney Disease
Being tested: Elecoglipron, Placebo
Keywords: Chronic kidney disease, Elecoglipron
Medical subject headings: Renal Insufficiency, Chronic

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

ElecoglipronDrug
Elicoglipron tablet
PlaceboDrug
Placebo tablet

Study groups in NCT07753993
Study group	Role	What they receive
Elecoglipron	Experimental	Elecoglipron tablet once daily Receives: Drug: Elecoglipron
Placebo	Active comparator	Placebo matching Elecoglipron tablet once daily Receives: Drug: Placebo

What is being measured

The primary outcome is the main question the study is designed to answer.

To evaluate the effect of elecoglipron compared with placebo in reducing the risk of the composite of ≥ 50% sustained decline in eGFR, ESKD, or all-cause mortality
Time to the first occurrence of any component of this composite:
- ≥ 50% sustained decline in eGFR
- ESKD defined as sustained eGFR < 10 mL/min/1.73 m2, or Chronic dialysis treatment, or Receiving a renal transplant
- All-cause mortality
Measured: Event-driven, trial is estimated to be up to 4.5 years

Secondary outcomes (9)

To evaluate the effect of elecoglipron compared with placebo in reducing the risk of the composite of ≥ 50% sustained decline in eGFR, ESKD, or CV and renal death
Time to the first occurrence of any component of this composite:
- ≥ 50% sustained decline in eGFR
- ESKD defined as: Sustained eGFR < 10 mL/min/1.73 m2, or Chronic dialysis treatment, or Receiving a renal transplant
- CV and renal death
Measured: Event-driven, trial is estimated to be up to 4.5 years
To evaluate the effect of elecoglipron compared with placebo in reducing the risk of composite of all-cause mortality, MI, or stroke
Time to the first occurrence of any component of this composite:
- All-cause mortality
- MI
- Stroke
Measured: Event-driven, trial is estimated to be up to 4.5 years
To evaluate the effect of elecoglipron compared with placebo in reducing the risk of MACE (CV death, MI, or stroke)
Time to the first occurrence of any component of this composite:
- CV and renal death
- MI
- Stroke
Measured: Event-driven, trial is estimated to be up to 4.5 years
To evaluate the effect of elecoglipron compared with placebo in reducing the risk of all-cause mortality
Time to death from any cause
Measured: Event-driven, trial is estimated to be up to 4.5 years
To evaluate the effect of elecoglipron compared with placebo in reducing the risk of CV death
Time to death from CV cause
Measured: Event-driven, trial is estimated to be up to 4.5 years
To evaluate the effect of elecoglipron compared with placebo in reducing the risk of the pure renal composite of ≥ 50% sustained decline in eGFR, ESKD, or renal death
Time to the first occurrence of any component of this composite:
- ≥ 50% sustained decline in eGFR
- ESKD defined as Sustained eGFR < 10 mL/min/1.73 m2, or Chronic dialysis treatment, or Receiving a renal transplant
- Renal death
Measured: Event-driven, trial is estimated to be up to 4.5 years
To evaluate the effect of elecoglipron compared with placebo in reducing the risk of CV death or HF hospitalizations
Time to the first occurrence of any component of this composite:
- CV death
- HF hospitalizations (hHF)
Measured: Event-driven, trial is estimated to be up to 4.5 years
To evaluate the effect of elecoglipron compared with placebo in reducing the risk of the composite endpoint of CV death, MI, stroke, or HF hospitalizations
Time to first occurrence of any component of this composite:
- CV death
- MI
- Stroke
- HF hospitalizations (hHF)
Measured: Event-driven, trial is estimated to be up to 4.5 years
To evaluate the effect of elecoglipron compared with placebo in reducing the risk of all-cause hospitalization
Time to hospitalization for any cause
Measured: Event-driven, trial is estimated to be up to 4.5 years

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

21 Aug 20264 Oct 2030

First posted10 Aug 2026
Study start21 Aug 2026
Primary completion4 Oct 2030 (estimated)
Study completion4 Oct 2030 (estimated)

Resources

Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
Other trials for Chronic Kidney DiseaseStudies of the same condition, open and under way.
More trials run by AstraZenecaThe sponsor's other registered studies.
What the trial phases meanHow a treatment moves from first tests in people to approval.

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design

Study type: Interventional
Phase: Phase 3
Primary purpose: Treatment
Allocation: Randomised
Intervention model: Parallel groups
Masking: Quadruple blind
Who is masked: Participant, Care provider, Investigator, Outcomes assessor
Enrolment: 7,000 participants (estimated)

IDs, dates and publications

ClinicalTrials.gov ID: NCT07753993
Sponsor's protocol ID: D7265C00001
Other IDs: 2025-523994-41-00, 2025
Acronym: Elevate-CKD
Status last verified: Sep 2026
First submitted: 4 Aug 2026
Last updated: 9 Sep 2026
Results posted: No
Data monitoring committee: Yes
FDA-regulated drug: Yes
FDA-regulated device: No
Individual data sharing: Yes: Qualified researchers can request access to anonymized individual patient-level data from AstraZeneca group of companies sponsored clinical trials via the request portal Vivli.org. All requests will be evaluated as per the AZ disclosure commitment: https://astrazenecagrouptrials.pharmacm.com/ST/Submission/Disclosure. Yes, indicates that AZ are accepting requests for IPD, but this does not mean all requests will be shared.

Interested in taking part?

AstraZeneca Clinical Study Information Center

1-877-240-9479

information.center@astrazeneca.com

Talk to your doctor first and take this page with you. Only the study team can confirm whether you can join.

Questions to ask the study team

What is the study trying to find out?
What would I need to do, and how often would I visit?
Could I receive a placebo instead of the treatment?
What are the possible risks and benefits for me?
Will it cost me anything? Are travel or time paid for?
Can I keep seeing my own doctor during the study?
What happens when the study ends?

See sites and contacts

Active, not recruitingPhase 2
Safety and Efficacy of Empagliflozin in Hemodialysis
End Stage Renal Disease
RecruitingPhase 3
Study to Assess the Efficacy, Pharmacokinetics, Safety and Tolerability of Atrasentan in Pediatric Patients With Primary IgAN
Berger Disease, Bergers Disease
Recruiting
Investigating Vascular Properties of HEMI and SPG Signals in Individuals With or at Risk for Chronic Kidney Disease
Chronic Kidney Disease, Hypertension (HTN)
Not yet recruiting
Hypothermic Kidney Machine Perfusion With Omnisol
End Stage Renal Disease (ESRD), Kidney Transplant
Not yet recruiting
An Individuation Intervention to Reduce Socioeconomic Disparities in Chronic Kidney Disease Care
Chronic Kidney Diseases

All Chronic Kidney Disease trials

Study at a glance

From the registry record, last updated by the sponsor on 9 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.

Official title: A Phase III, Randomized, Double-blind, Parallel-group, Placebo-controlled Multicenter Study to Evaluate the Effect of Elecoglipron in Reducing Renal Outcomes and Mortality in Participants With Chronic Kidney Disease (Elevate-CKD)
ClinicalTrials.gov ID: NCT07753993
Acronym / sponsor ID: Elevate-CKD / D7265C00001
Conditions: Chronic Kidney Disease
Keywords: Chronic kidney disease, Elecoglipron
Phase: Phase 3
Study type: Interventional
Recruitment status: Recruiting
Enrolment: 7,000 participants (estimated)
Lead sponsor: AstraZenecaIndustry (pharma, biotech, devices)
Study start: 21 Aug 2026 (actual)
Primary completion: 4 Oct 2030 (estimated)
Study completion: 4 Oct 2030 (estimated)
First posted: 10 Aug 2026 (actual)
Results: Not posted in the source record

Clinical summary

The research question as the sponsor registered it. This describes what the study plans to test, not what it found.

Study design

Primary purpose: Treatment
Allocation: Randomised
Intervention model: Parallel groups
Masking: Quadruple blind (participant, care provider, investigator, outcomes assessor)
Number of arms: 2

Arm	Type	Receives
Elecoglipron	Experimental	Drug: ElecoglipronElecoglipron tablet once daily
Placebo	Active comparator	Drug: PlaceboPlacebo matching Elecoglipron tablet once daily

Who may qualify

Ages: 18 years and older
Sex: All
Healthy volunteers: Not accepted
Age groups: Adult, Older adult

Key inclusion criteria (2 listed)

Adults with confirmed CKD; UACR ≥30 mg/g and eGFR ≥20 mL/min/1.73 m² within specified ranges.
On stable, patient maximum tolerated, labeled daily dose of ACEI or ARB for ≥4 weeks at least 28 days before screening.

Key exclusion criteria (9 listed)

BMI <23 kg/m² at screening
History of type 1 diabetes mellitus
HbA1c ≥10% (86 mmol/mol) at screening
Currently receiving, or anticipated to receive, therapeutic intervention for diabetic retinopathy and/or macular edema.
Have had more than one episode of severe hypoglycemia within 180 days prior to screening, or hypoglycemia unawareness

Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.

Interventions

Intervention	Type	Arms
ElecoglipronElicoglipron tablet	Drug	Elecoglipron
PlaceboPlacebo tablet	Drug	Placebo

Primary outcome

To evaluate the effect of elecoglipron compared with placebo in reducing the risk of the composite of ≥ 50% sustained decline in eGFR, ESKD, or all-cause mortality
Time frame: Event-driven, trial is estimated to be up to 4.5 years
Time to the first occurrence of any component of this composite: * ≥ 50% sustained decline in eGFR * ESKD defined as sustained eGFR < 10 mL/min/1.73 m2, or Chronic dialysis treatment, or Receiving a renal transplant * All-cause mortality

9 secondary outcomes

To evaluate the effect of elecoglipron compared with placebo in reducing the risk of the composite of ≥ 50% sustained decline in eGFR, ESKD, or CV and renal death
Time frame: Event-driven, trial is estimated to be up to 4.5 years
To evaluate the effect of elecoglipron compared with placebo in reducing the risk of composite of all-cause mortality, MI, or stroke
Time frame: Event-driven, trial is estimated to be up to 4.5 years
To evaluate the effect of elecoglipron compared with placebo in reducing the risk of MACE (CV death, MI, or stroke)
Time frame: Event-driven, trial is estimated to be up to 4.5 years
To evaluate the effect of elecoglipron compared with placebo in reducing the risk of all-cause mortality
Time frame: Event-driven, trial is estimated to be up to 4.5 years
To evaluate the effect of elecoglipron compared with placebo in reducing the risk of CV death
Time frame: Event-driven, trial is estimated to be up to 4.5 years
To evaluate the effect of elecoglipron compared with placebo in reducing the risk of the pure renal composite of ≥ 50% sustained decline in eGFR, ESKD, or renal death
Time frame: Event-driven, trial is estimated to be up to 4.5 years
To evaluate the effect of elecoglipron compared with placebo in reducing the risk of CV death or HF hospitalizations
Time frame: Event-driven, trial is estimated to be up to 4.5 years
To evaluate the effect of elecoglipron compared with placebo in reducing the risk of the composite endpoint of CV death, MI, stroke, or HF hospitalizations
Time frame: Event-driven, trial is estimated to be up to 4.5 years
To evaluate the effect of elecoglipron compared with placebo in reducing the risk of all-cause hospitalization
Time frame: Event-driven, trial is estimated to be up to 4.5 years

Results and safety

This study is still under way. Results are not available in the source record yet.

Research links

Official record on ClinicalTrials.govLast updated by the sponsor 9 Sep 2026.
Individual participant dataSharing planned: Yes. Qualified researchers can request access to anonymized individual patient-level data from AstraZeneca group of companies sponsored clinical trials via the request portal Vivli.org. All requests will be evaluated as per the AZ disclosure commitment: https://astrazenecagrouptrials.pharmacm.com/ST/Submission/Disclosure. Yes, indicates that AZ are accepting requests for IPD, but this does not mean all requests will be shared.

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Referral and contact

AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.

AstraZeneca Clinical Study Information Center contact

1-877-240-9479

information.center@astrazeneca.com

715 sites in 37 countries: see every site and its status.

Questions about this trial

What is this clinical trial studying?

A Phase 3 study testing Elecoglipron in people with Chronic Kidney Disease, run by AstraZeneca at 715 sites in 37 countries.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 2 inclusion and 9 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: looking for participants now, as of the sponsor's last update on 9 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 715 sites in United States, China, Japan, Germany, India and 32 more countries. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

What does this phase mean?

Phase 3 studies compare the treatment with the current standard treatment or a placebo in a large group, to confirm how well it works and watch for side effects.

Not every study follows the same path, and some studies (observational studies, device studies) have no phase.

Are results available for this study?

This study is still under way. Results are not available in the source record yet.

How can a doctor refer a patient or contact the research team?

Contact AstraZeneca Clinical Study Information Center (1-877-240-9479, information.center@astrazeneca.com), or a site near the patient. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

To evaluate the effect of elecoglipron compared with placebo in reducing the risk of the composite of ≥ 50% sustained decline in eGFR, ESKD, or all-cause mortality (time frame: Event-driven, trial is estimated to be up to 4.5 years). It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT07753993.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 9 Sep 2026.