Multiple SclerosisNCT07759115
Music-4-MS to Improve Cognition in People Living With Multiple Sclerosis: A Feasibility Study
A study testing Music Training Intervention and Music Listening in people with Multiple Sclerosis and Pathologic Processes, run by University of Texas at Austin at 1 site in United States.
Trial summary
Multiple sclerosis (MS) rates in the U.S. have nearly doubled over the past decade, making it a leading cause of nontraumatic functional impairment in young adults and significantly affecting cognitive function in up to 70% of people with MS. Read more about this study
- Who is it for?
- Ages 18 to 80 years
- Conditions the study is for
- Multiple Sclerosis, Pathologic Processes, Demyelinating Autoimmune Diseases, CNS
- What is being tested?
- Music Training Intervention and Music Listening
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 64 participants
- Where
- 1 siteUnited States
- Study dates
- 10 Aug 2026to Aug 2028
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 80 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Diagnosed with multiple sclerosis (relapsing remitting, secondary progressive, primary progressive)
- Diagnosed more than 6 months prior to starting study
- Self-reported cognitive impairment as assessed by having at leased 5 problems "sometimes" or more often on the Perceived Deficits Questionnaire
- Read, write, and understand English
- Access to internet
Who cannot join
- Diagnosed with another neurological condition that causes cognitive impairment
- MS exacerbation within the last 30 days
- Professional musician (primary source of income)
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site, 1 recruiting
- Recruiting
University of Texas at Austin
Austin, Texas, 78712
Carolyn Phillips, PhD, RN, 512-475-7039, music4ms@nursing.utexas.edu
About this study
Official title: A Randomized Controlled Trial of Music-4-MS Compared to Music Listening to Improve Cognition in People Living With Multiple Sclerosis: A Feasibility Study
Multiple sclerosis (MS) rates in the U.S. have nearly doubled over the past decade, making it a leading cause of nontraumatic functional impairment in young adults and significantly affecting cognitive function in up to 70% of people with MS. While traditional cognitive rehabilitation methods are limited in sensory engagement, music training offers a multisensory approach that enhances neuroplasticity and improves cognitive functions. This study investigates the feasibility of Music-4-MS, a 12-week music-based eHealth intervention, to support cognitive and emotional health in individuals with MS.
Read the detailed description
Multiple sclerosis (MS) affects more than 2.8 million people worldwide; its prevalence has increased in every region and nearly doubled in the U.S. since 2013. In many countries, MS is the main cause of nontraumatic disability in young adults. The course of MS is unpredictable, and common symptoms in persons with MS include impaired day-to-day activities such as walking, cognitive impairment, vision problems, paresthesia in the extremities, trouble sleeping, and chronic pain. Physical difficulties associated with MS contribute to secondary symptoms of depression, anxiety, and fatigue.
Cognitive impairment affects up to 70% of people with MS, and the incidence of early-onset dementia is 7 times higher than it is in adults without MS. Impairments like slowed processing, poor memory, and learning difficulties impact quality of life, social, and occupational functioning. Working memory deficits are associated with reduced connectivity between brain regions, especially the frontal and parietal lobes, during memory encoding, maintenance, and recall. Cognitive-based rehabilitation, however, can improve memory and learning as well as symptoms of depression and anxiety, which may reinforce cognition. Traditional approaches to cognitive rehabilitation use restorative (drill-and-practice) and compensatory (management) strategies. Yet most cognitive interventions for persons with MS are predominantly visual or speech-focused, which eliminates the possibility of stimulating multiple senses.
Music consists of complex, multidomain stimuli that engage a large bilateral network of temporal, frontal, parietal, cerebellar, limbic, and paralimbic brain areas associated with multiple parallel cognitive, verbal, motor, and emotional processes. Playing a musical instrument involves intricate coordination and communication between multiple sensory systems (visual, auditory, tactile) and motor functions. As individuals read and translate musical notes into physical actions, they simultaneously receive feedback from their auditory system. The ability to engage these systems and coordinate multiple domains may induce new cortical pathways fostering neuroplasticity. This rewiring in the brain created by repeated musical practice can create alternate pathways and structures to help those with MS compensate for deficits caused by demyelinating disease. Music interventions for other neurodegenerative conditions have been studied, but very few have been implemented for those with MS. A recent systematic review evaluated the impact of active (singing, dancing, instrument playing) and passive (listening) music interventions on psychosocial and neurological outcomes in individuals with MS. Of the 15 studies reviewed, none examined a music learning intervention and the impact on cognitive impairment-a critical gap to be addressed.
Our multi-disciplinary team has conducted a proof-of-concept study to evaluate an innovative ukulele training intervention, Music-4-MS, to address the gap in cognitive rehabilitation for persons with MS. Based on the feedback from participants in that study, our team of experts in human and music learning, music therapy, neuroscience, nursing, and cognitive rehabilitation optimized Music-4-MS. The primary goal of the present study is to evaluate the feasibility of the optimized Music-4-MS as a manualized eHealth intervention. Guided by the therapeutic music capacities model, Music-4-MS will support cognitive, psychosocial, and functional well-being. In a prospective, randomized (1:1) trial with 64 individuals with MS recruited nationwide, the Music-4-MS group will be compared with an active control group. This will be a step toward a larger clinical trial to test the intervention's efficacy in improving MS health outcomes. The specific aims are as follows:
Aim 1: To determine the feasibility and acceptability of delivering the optimized Music-4-MS eHealth intervention to individuals with MS over 12 weeks.
Aim 2: To evaluate the preliminary effect of the optimized Music-4-MS on cognitive (objective performance, subjective function), psychosocial (anxiety, depression, social function), and functional (physical function, fatigue, hand dexterity) well-being over time in the Music-4-MS versus the active control group.
Aim 3: To explore participants' perceptions of the motivation, engagement, connection, and usefulness of Music-4-MS in their daily lives.
- Conditions
- Multiple Sclerosis, Pathologic Processes, Demyelinating Autoimmune Diseases, CNS, Autoimmune Diseases of the Nervous System, Nervous System Diseases, Demyelinating Diseases
- Being tested
- Music Training Intervention, Music Listening
- Keywords
- Cognitive rehabilitation
- Medical subject headings
- Multiple Sclerosis, Pathologic Processes, Demyelinating Autoimmune Diseases, CNS, Autoimmune Diseases of the Nervous System, Nervous System Diseases, Demyelinating Diseases, Autoimmune Diseases, Immune System Diseases
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Music Training InterventionBehavioural
The Music Training Intervention (MTI) entails 12-weeks of online instruction to learn to play the ukulele. Participants will be taught the basic information on how to hold the ukulele, musical chords, strum and play popular songs. They will be instructed to play at least 30-minutes a day, five days a week.
Music ListeningBehavioural
Participants randomized to this arm will be asked to listen to their preferred music for at least 30 minutes, 5 days a week. A member of our research team will call them every week to answer any questions they have about the ML protocol. They will be asked to record their experience in a daily log
| Study group | Role | What they receive |
|---|---|---|
| Musical Training Intervention | Experimental | Participants randomized to this arm receive a 12-week intervention to teach them how to play the ukulele. The ukulele is a very manageable instrument to learn and requires less hand dexterity than other stringed instruments. Each week participants will follow the musical training intervention (MTI) protocol that provides instruction on how to tune, hold, and strum the ukulele and play basic chords. To practice the chords, they will also learn popular songs (e.g., Chain of Fools, Three Little Birds, Happy Birthday, Just the Way You Are, and Coconut). Participants will be instructed to follow each session outlined weekly and asked to practice the instrument for at least 30 minutes, 5 days a week. They will be given a paper and digital version of the MTI protocol. A member of our research team will call the participants weekly to answer any questions about the MTI protocol. Receives: Behavioral: Music Training Intervention |
| Music Listening | Active comparator | Participants randomized to this arm will be asked to listen to their preferred music for at least 30 minutes, 5 days a week. A member of our research team will call them every week to answer any questions they have about the ML protocol. They will be asked to record their experience in a daily log. Receives: Behavioral: Music Listening |
What is being measured
The primary outcome is the main question the study is designed to answer.
Feasibility: Engagement
Feasibility will be assessed by quantifying weekly participation in Music-4-MS using the activity metrics from the online platform Teachable.
Measured: Immediately post-intervention
Feasibility: Retention
Feasibility will be evaluated by quantifying how many participants drop out throughout the course of the study.
Measured: Immediately post-intervention
Feasibility: Recruitment
Feasibility will be assessed by quantifying how many people accept the invitation to participate in the study.
Measured: Immediately post-intervention
Musical Training Intervention Acceptability
Acceptability will be evaluated with semi-structured interview questions to understand the participant's perception of MTI delivery and content and the perceived impact.
Measured: Immediately post-intervention
Music Listening Intervention Acceptability
Acceptability will be assessed by having participants rate a series of eight statements from 1 (Strongly Disagree) to 7 (Strongly Agree), and answer three open-ended questions based on their experience with the music listening program.
Measured: Immediately post-intervention
Secondary outcomes (10)
Mean Change from Baseline in Functional Well-Being Scores at 12 weeks and 16 weeks
The Patient-Reported Outcomes Measurement Information System (PROMIS)-29 Profile v2.0 will be used. The survey measures physical function, anxiety, depression, fatigue, sleep disturbance, ability to participate in social roles and activities, and pain interference. Each domain is scored from 4 to 20.
Measured: Immediately post-intervention and 1-month post-intervention
Mean Change from Baseline in Cognitive Function at 12 weeks and 16 weeks
The Patient-Reported Outcomes Measurement Information System (PROMIS) Cognition Function Short-Form will be used. The minimum score is 8, and the maximum score is 40. Higher scores indicate more cognitive impairment.
Measured: Immediately post-intervention and 1-month post-intervention
Mean Change from Baseline in Upper Extremity Function Scores at 12 weeks and 16 weeks
The Patient-Reported Outcomes Measurement Information System (PROMIS) Upper Extremity Function (Fine Motor, ADL) - Short Form will be used. The minimum score is 8, and the maximum score is 40. Higher scores indicate more more upper extremity function.
Measured: Immediately post-intervention and 1-month post-intervention
Mean Change from Baseline in Objective Hand Dexterity Scores at 12 weeks and 16 weeks
The 9-Hole Peg Test (9HPT) will be used. The 9HPT is a timed task completed with both hands independently, with a lower time indicating more hand dexterity.
Measured: Immediately post-intervention and 1-month post-intervention
Mean Change from Baseline in Subjective Hand Dexterity Scores at 12 weeks and 16 weeks
The ABILHAND Questionnaire will be used. There are 26 activities listed and the participants responds with impossible, difficult, or easy to complete. An increased number of impossible and difficult responses indicates lower hand dexterity.
Measured: Immediately post-intervention and 1-month post-intervention
Mean Change from Baseline in Loneliness Scores at 12 weeks and 16 weeks.
The NIH Toolbox - Emotional Battery Loneliness will be used. It is a 5-item survey with responses graded on a 5-point scale from 'never' to 'always' assessing feelings of loneliness and social isolation.
Measured: Immediately post-intervention and 1-month post-intervention
Mean Change from Baseline in Attention Scores at 12 weeks and 16 weeks
The Trail Making A\&B will be used to measure attention. Trails A and B are two separate timed tests. Faster time means greater attention.
Measured: Immediately post-intervention and 1-month post-intervention
Mean Change from Baseline in Memory Scores at 12 weeks and 16 weeks
Immediate and delayed recognition tests will be used. Participant are shown 10 words to memorize. In the immediate recognition test, they are immediately asked to identify the 10 words they memorized out of a list of 20. Later in the testing series, participants will again be asked to recall the 10 words. The number of correct responses will be scored. Higher scores means better memory.
Measured: Immediately post-intervention and 1-month post-intervention
Mean Change from Baseline in Executive Functioning Scores at 12 weeks and 16 weeks
The Digit-Symbol Substitution will be used to measure processing speed and accuracy to evaluate executive functioning. In this test, participants match arbitrary symbols to digits. Scores are calculated by the number of trials correctly completed in 60 seconds.
Measured: Immediately post-intervention and 1-month post-intervention
Mean Change from Baseline in Executive Functioning Scores at 12 weeks and 16 weeks
The Stroop Color and Word Test evaluates impulse control and inhibition to evaluate executive functioning. When the name of a color (e.g., "blue," "green," or "red") is displayed in an incongruent color, name (for example, the word "blue" printed in red), naming the color of the word takes longer and is more prone to errors than when the word and color are congruent or neutral. The scoring uses median duration of incongruent trials.
Measured: Immediately post-intervention and 1-month post-intervention
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted12 Aug 2026
- Study start10 Aug 2026
- Primary completionMar 2028 (estimated)
- Study completionAug 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Multiple SclerosisStudies of the same condition, open and under way.
- More trials run by University of Texas at AustinThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Care provider, Outcomes assessor
- Enrolment
- 64 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of Texas at Austin
- Sponsor type
- University, hospital or other
- Collaborators
- National Institute of Nursing Research (NINR)
- Responsible party
- Principal investigator, Carolyn Phillips, University of Texas at Austin
- Investigators
- Carolyn Phillips, PhD, Principal investigator, University of Texas at Austin
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07759115
- Sponsor's protocol ID
- STUDY00008963
- Other IDs
- R21NR022143
- Status last verified
- Aug 2026
- First submitted
- 5 Aug 2026
- Last updated
- 17 Aug 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 17 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- A Randomized Controlled Trial of Music-4-MS Compared to Music Listening to Improve Cognition in People Living With Multiple Sclerosis: A Feasibility Study
- ClinicalTrials.gov ID
- NCT07759115
- Acronym / sponsor ID
- STUDY00008963
- Conditions
- Multiple Sclerosis, Pathologic Processes, Demyelinating Autoimmune Diseases, CNS, Autoimmune Diseases of the Nervous System, Nervous System Diseases, Demyelinating Diseases
- Keywords
- Cognitive rehabilitation
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 64 participants (estimated)
- Lead sponsor
- University of Texas at AustinUniversity, hospital or other
- Collaborators
- National Institute of Nursing Research (NINR)
- Study start
- 10 Aug 2026 (actual)
- Primary completion
- Mar 2028 (estimated)
- Study completion
- Aug 2028 (estimated)
- First posted
- 12 Aug 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Multiple sclerosis (MS) rates in the U.S. have nearly doubled over the past decade, making it a leading cause of nontraumatic functional impairment in young adults and significantly affecting cognitive function in up to 70% of people with MS. While traditional cognitive rehabilitation methods are limited in sensory engagement, music training offers a multisensory approach that enhances neuroplasticity and improves cognitive functions. This study investigates the feasibility of Music-4-MS, a 12-week music-based eHealth intervention, to support cognitive and emotional health in individuals with MS.
Detailed description
Multiple sclerosis (MS) affects more than 2.8 million people worldwide; its prevalence has increased in every region and nearly doubled in the U.S. since 2013. In many countries, MS is the main cause of nontraumatic disability in young adults. The course of MS is unpredictable, and common symptoms in persons with MS include impaired day-to-day activities such as walking, cognitive impairment, vision problems, paresthesia in the extremities, trouble sleeping, and chronic pain. Physical difficulties associated with MS contribute to secondary symptoms of depression, anxiety, and fatigue.
Cognitive impairment affects up to 70% of people with MS, and the incidence of early-onset dementia is 7 times higher than it is in adults without MS. Impairments like slowed processing, poor memory, and learning difficulties impact quality of life, social, and occupational functioning. Working memory deficits are associated with reduced connectivity between brain regions, especially the frontal and parietal lobes, during memory encoding, maintenance, and recall. Cognitive-based rehabilitation, however, can improve memory and learning as well as symptoms of depression and anxiety, which may reinforce cognition. Traditional approaches to cognitive rehabilitation use restorative (drill-and-practice) and compensatory (management) strategies. Yet most cognitive interventions for persons with MS are predominantly visual or speech-focused, which eliminates the possibility of stimulating multiple senses.
Music consists of complex, multidomain stimuli that engage a large bilateral network of temporal, frontal, parietal, cerebellar, limbic, and paralimbic brain areas associated with multiple parallel cognitive, verbal, motor, and emotional processes. Playing a musical instrument involves intricate coordination and communication between multiple sensory systems (visual, auditory, tactile) and motor functions. As individuals read and translate musical notes into physical actions, they simultaneously receive feedback from their auditory system. The ability to engage these systems and coordinate multiple domains may induce new cortical pathways fostering neuroplasticity. This rewiring in the brain created by repeated musical practice can create alternate pathways and structures to help those with MS compensate for deficits caused by demyelinating disease. Music interventions for other neurodegenerative conditions have been studied, but very few have been implemented for those with MS. A recent systematic review evaluated the impact of active (singing, dancing, instrument playing) and passive (listening) music interventions on psychosocial and neurological outcomes in individuals with MS. Of the 15 studies reviewed, none examined a music learning intervention and the impact on cognitive impairment-a critical gap to be addressed.
Our multi-disciplinary team has conducted a proof-of-concept study to evaluate an innovative ukulele training intervention, Music-4-MS, to address the gap in cognitive rehabilitation for persons with MS. Based on the feedback from participants in that study, our team of experts in human and music learning, music therapy, neuroscience, nursing, and cognitive rehabilitation optimized Music-4-MS. The primary goal of the present study is to evaluate the feasibility of the optimized Music-4-MS as a manualized eHealth intervention. Guided by the therapeutic music capacities model, Music-4-MS will support cognitive, psychosocial, and functional well-being. In a prospective, randomized (1:1) trial with 64 individuals with MS recruited nationwide, the Music-4-MS group will be compared with an active control group. This will be a step toward a larger clinical trial to test the intervention's efficacy in improving MS health outcomes. The specific aims are as follows:
Aim 1: To determine the feasibility and acceptability of delivering the optimized Music-4-MS eHealth intervention to individuals with MS over 12 weeks.
Aim 2: To evaluate the preliminary effect of the optimized Music-4-MS on cognitive (objective performance, subjective function), psychosocial (anxiety, depression, social function), and functional (physical function, fatigue, hand dexterity) well-being over time in the Music-4-MS versus the active control group.
Aim 3: To explore participants' perceptions of the motivation, engagement, connection, and usefulness of Music-4-MS in their daily lives.
Study design
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (care provider, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Musical Training Intervention | Experimental | Behavioral: Music Training InterventionParticipants randomized to this arm receive a 12-week intervention to teach them how to play the ukulele. The ukulele is a very manageable instrument to learn and requires less hand dexterity than other stringed instruments. Each week participants will follow the musical training intervention (MTI) protocol that provides instruction on how to tune, hold, and strum the ukulele and play basic chords. To practice the chords, they will also learn popular songs (e.g., Chain of Fools, Three Little Birds, Happy Birthday, Just the Way You Are, and Coconut). Participants will be instructed to follow each session outlined weekly and asked to practice the instrument for at least 30 minutes, 5 days a week. They will be given a paper and digital version of the MTI protocol. A member of our research team will call the participants weekly to answer any questions about the MTI protocol. |
| Music Listening | Active comparator | Behavioral: Music ListeningParticipants randomized to this arm will be asked to listen to their preferred music for at least 30 minutes, 5 days a week. A member of our research team will call them every week to answer any questions they have about the ML protocol. They will be asked to record their experience in a daily log. |
Who may qualify
- Ages
- 18 to 80 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (5 listed)
- Diagnosed with multiple sclerosis (relapsing remitting, secondary progressive, primary progressive)
- Diagnosed more than 6 months prior to starting study
- Self-reported cognitive impairment as assessed by having at leased 5 problems "sometimes" or more often on the Perceived Deficits Questionnaire
- Read, write, and understand English
- Access to internet
Key exclusion criteria (3 listed)
- Diagnosed with another neurological condition that causes cognitive impairment
- MS exacerbation within the last 30 days
- Professional musician (primary source of income)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Music Training InterventionThe Music Training Intervention (MTI) entails 12-weeks of online instruction to learn to play the ukulele. Participants will be taught the basic information on how to hold the ukulele, musical chords, strum and play popular songs. They will be instructed to play at least 30-minutes a day, five days a week. | Behavioural | Musical Training Intervention |
| Music ListeningParticipants randomized to this arm will be asked to listen to their preferred music for at least 30 minutes, 5 days a week. A member of our research team will call them every week to answer any questions they have about the ML protocol. They will be asked to record their experience in a daily log | Behavioural | Music Listening |
Primary outcome
Feasibility: Engagement
Time frame: Immediately post-intervention
Feasibility will be assessed by quantifying weekly participation in Music-4-MS using the activity metrics from the online platform Teachable.
Feasibility: Retention
Time frame: Immediately post-intervention
Feasibility will be evaluated by quantifying how many participants drop out throughout the course of the study.
Feasibility: Recruitment
Time frame: Immediately post-intervention
Feasibility will be assessed by quantifying how many people accept the invitation to participate in the study.
Musical Training Intervention Acceptability
Time frame: Immediately post-intervention
Acceptability will be evaluated with semi-structured interview questions to understand the participant's perception of MTI delivery and content and the perceived impact.
Music Listening Intervention Acceptability
Time frame: Immediately post-intervention
Acceptability will be assessed by having participants rate a series of eight statements from 1 (Strongly Disagree) to 7 (Strongly Agree), and answer three open-ended questions based on their experience with the music listening program.
10 secondary outcomes
Mean Change from Baseline in Functional Well-Being Scores at 12 weeks and 16 weeks
Time frame: Immediately post-intervention and 1-month post-intervention
Mean Change from Baseline in Cognitive Function at 12 weeks and 16 weeks
Time frame: Immediately post-intervention and 1-month post-intervention
Mean Change from Baseline in Upper Extremity Function Scores at 12 weeks and 16 weeks
Time frame: Immediately post-intervention and 1-month post-intervention
Mean Change from Baseline in Objective Hand Dexterity Scores at 12 weeks and 16 weeks
Time frame: Immediately post-intervention and 1-month post-intervention
Mean Change from Baseline in Subjective Hand Dexterity Scores at 12 weeks and 16 weeks
Time frame: Immediately post-intervention and 1-month post-intervention
Mean Change from Baseline in Loneliness Scores at 12 weeks and 16 weeks.
Time frame: Immediately post-intervention and 1-month post-intervention
Mean Change from Baseline in Attention Scores at 12 weeks and 16 weeks
Time frame: Immediately post-intervention and 1-month post-intervention
Mean Change from Baseline in Memory Scores at 12 weeks and 16 weeks
Time frame: Immediately post-intervention and 1-month post-intervention
Mean Change from Baseline in Executive Functioning Scores at 12 weeks and 16 weeks
Time frame: Immediately post-intervention and 1-month post-intervention
Mean Change from Baseline in Executive Functioning Scores at 12 weeks and 16 weeks
Time frame: Immediately post-intervention and 1-month post-intervention
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 17 Aug 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Carolyn Phillips, PhD principal investigator
University of Texas at Austin
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Music Training Intervention and Music Listening in people with Multiple Sclerosis and Pathologic Processes, run by University of Texas at Austin at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 17 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Carolyn Phillips, PhD, RN (512-475-7039, carolyn.phillips@nursing.utexas.edu), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Feasibility: Engagement (time frame: Immediately post-intervention). The study lists 5 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 17 Aug 2026.