LipedemaNCT07779603
The Relationship Between Lipedema and Osteoporosis
An observational study of Lipedema and Osteoporosis, run by Fatih Sultan Mehmet Training and Research Hospital.
Trial summary
The purpose of this study is to evaluate the relationship between lipedema and osteoporosis and to examine factors that may be associated with osteoporosis in individuals with lipedema. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Lipedema, Osteoporosis
- What is being tested?
- DXA
- How many people
- 120 participants
- Where
- No sites listed yet
- Study dates
- 20 Aug 2026to 16 Sep 2026
- How long will I take part?
- 1 Day
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: postmenopausal patients with or without a diagnosis of lipedema
Who may be able to join
- being literate
- voluntarily agreeing to participate in the study
- being a postmenopausal woman
- having a diagnosis of lipedema
Who cannot join
- the presence of other types of edema in which a component other than lipedema predominates (e.g., lymphedema, venous edema, edema associated with heart or kidney failure, etc.)
- chronic liver disease,
- body mass index (BMI) of over 50.0 (this condition reflects severe obesity, which has a significant impact on health beyond lipedema alone)
- the presence of rheumatological diseases that may lead to secondary osteoporosis
- a history of cancer, endocrine disorders, neurological disorders, certain gastrointestinal disorders
- use of medications related to osteoporosis
- being under 18 years of age
About this study
Official title: The Relationship Between Lipedema and Osteoporosis: A Cross-Sectional Observational Study
The purpose of this study is to evaluate the relationship between lipedema and osteoporosis and to examine factors that may be associated with osteoporosis in individuals with lipedema.
Read the detailed description
Clinical characteristics such as age, body mass index (BMI), education level, marital status, age at menopause, number of births, duration of illness, occupation, duration of lactation, history of fractures, family history of fractures, smoking, alcohol consumption, dairy product intake, sun exposure habits, stage of lipedema, and type of lipedema will be recorded. Your blood test results obtained prior to routine osteoporosis treatment (complete blood count, erythrocyte sedimentation rate, C-reactive protein, calcium, phosphorus, alkaline phosphatase (ALP), parathyroid hormone (PTH), and 25-hydroxyvitamin D levels) will be recorded. The severity of lower extremity pain will be assessed using the Visual Analog Scale (VAS). Scores on the lower extremity functional scale will be recorded. For patients with lipedema, the average and most severe lower extremity pain experienced over the past month will be recorded. Dual-energy X-ray absorptiometry (DEXA) measurements assessing current bone loss will be recorded for the lumbar and hip regions.
- Conditions
- Lipedema, Osteoporosis
- Being tested
- DXA
- Medical subject headings
- Lipedema, Osteoporosis
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
DXAOther
Dual-energy X-ray absorptiometry (DXA) measurements will be recorded for the lumbar and hip regions
| Study group | Role | What they receive |
|---|---|---|
| Group1 | postmenopausal patients diagnosed with lipedema Receives: Other: DXA | |
| Group2 | postmenopausal patients without lipedema Receives: Other: DXA |
What is being measured
The primary outcome is the main question the study is designed to answer.
DXA
Dual-energy X-ray absorptiometry (DEXA) measurements for the lumbar and hip regions for the lumbar and hip regions
Measured: 1 day
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted21 Aug 2026
- Study start20 Aug 2026 (estimated)
- Primary completion16 Sep 2026 (estimated)
- Study completion16 Sep 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for LipedemaStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case-control
- Time perspective
- Cross-sectional
- Enrolment
- 120 participants (estimated)
- Target duration
- 1 Day
Sponsor and investigators
- Lead sponsor
- Fatih Sultan Mehmet Training and Research Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07779603
- Sponsor's protocol ID
- FSMLIPEDEMAOP
- Status last verified
- Aug 2026
- First submitted
- 18 Aug 2026
- Last updated
- 21 Aug 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 21 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Relationship Between Lipedema and Osteoporosis: A Cross-Sectional Observational Study
- ClinicalTrials.gov ID
- NCT07779603
- Acronym / sponsor ID
- FSMLIPEDEMAOP
- Conditions
- Lipedema, Osteoporosis
- Study type
- Observational
- Recruitment status
- Not yet recruiting
- Enrolment
- 120 participants (estimated)
- Lead sponsor
- Fatih Sultan Mehmet Training and Research HospitalUniversity, hospital or other
- Study start
- 20 Aug 2026 (estimated)
- Primary completion
- 16 Sep 2026 (estimated)
- Study completion
- 16 Sep 2026 (estimated)
- First posted
- 21 Aug 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of this study is to evaluate the relationship between lipedema and osteoporosis and to examine factors that may be associated with osteoporosis in individuals with lipedema.
Detailed description
Clinical characteristics such as age, body mass index (BMI), education level, marital status, age at menopause, number of births, duration of illness, occupation, duration of lactation, history of fractures, family history of fractures, smoking, alcohol consumption, dairy product intake, sun exposure habits, stage of lipedema, and type of lipedema will be recorded. Your blood test results obtained prior to routine osteoporosis treatment (complete blood count, erythrocyte sedimentation rate, C-reactive protein, calcium, phosphorus, alkaline phosphatase (ALP), parathyroid hormone (PTH), and 25-hydroxyvitamin D levels) will be recorded. The severity of lower extremity pain will be assessed using the Visual Analog Scale (VAS). Scores on the lower extremity functional scale will be recorded. For patients with lipedema, the average and most severe lower extremity pain experienced over the past month will be recorded. Dual-energy X-ray absorptiometry (DEXA) measurements assessing current bone loss will be recorded for the lumbar and hip regions.
Study design
- Observational model
- Case-control
- Time perspective
- Cross-sectional
- Target follow-up
- 1 Day
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Group1 | – | Other: DXApostmenopausal patients diagnosed with lipedema |
| Group2 | – | Other: DXApostmenopausal patients without lipedema |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- postmenopausal patients with or without a diagnosis of lipedema
Key inclusion criteria (4 listed)
- being literate
- voluntarily agreeing to participate in the study
- being a postmenopausal woman
- having a diagnosis of lipedema
Key exclusion criteria (7 listed)
- the presence of other types of edema in which a component other than lipedema predominates (e.g., lymphedema, venous edema, edema associated with heart or kidney failure, etc.)
- chronic liver disease,
- body mass index (BMI) of over 50.0 (this condition reflects severe obesity, which has a significant impact on health beyond lipedema alone)
- the presence of rheumatological diseases that may lead to secondary osteoporosis
- a history of cancer, endocrine disorders, neurological disorders, certain gastrointestinal disorders
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| DXADual-energy X-ray absorptiometry (DXA) measurements will be recorded for the lumbar and hip regions | Other | Group1, Group2 |
Primary outcome
DXA
Time frame: 1 day
Dual-energy X-ray absorptiometry (DEXA) measurements for the lumbar and hip regions for the lumbar and hip regions
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 21 Aug 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
The record lists no contact. Use the official record to reach the sponsor.
Questions about this trial
What is this clinical trial studying?
An observational study of Lipedema and Osteoporosis, run by Fatih Sultan Mehmet Training and Research Hospital.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 21 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
DXA (time frame: 1 day). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 21 Aug 2026.