Clinical trials: Lipedema
Lipedema
HYPOXI for Women With Lipedema
The proposed study is for women with lipedema, a painful fat disorder where fat cannot be lost from the legs and hips with diet and exercise.
- Trial name
- NCT03853083
- Testing
- Hypoxi Equipment, Recumbent Bicycle
- Volunteers
- 20 people
- Sponsor
- University of Arizona
Lipedema, Knee Osteoarthritis
The Effect of Lipedema on Knee Osteoarthritis
This study will be one of the few to examine the effect of lipedema on knee osteoarthritis in a comparative manner with a control group within the same osteoarthritis context.
- Conditions
- Lipedema, Knee Osteoarthritis, Knee Acute and Chronic Pain, Knee
- Trial name
- NCT07575555
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Izmir Democracy University
Lipedema
Effect of Ultrasound Cavitation Versus Pneumatic Compression on Adipose Tissue Thickness on Lipedema Patients
PURPOSE: This study will be conducted to investigate any significant effect of ultrasound fat cavitation or pneumatic compression on adipose tissue thickness in patients with lipedema.
- Trial name
- NCT07404059
- Testing
- fat cavitation
- Where
- Egypt
- Sponsor
- Cairo University
Lipedema, Lymphedema
Investigation of Lipedema, Lymphedema and Vascular Malformations by Multispectral Optoacoustic Tomography (MSOT)
This study aims to analyze the fatty tissue architecture of the subcutaneous tissue in patients from the plastic surgery department.
- Conditions
- Lipedema, Lymphedema, Vascular Malformations
- Trial name
- NCT06399367
- Testing
- MSOT
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University Hospital Goettingen
Vitamin D Deficiency, B12 Deficiency Vitamin
Relationship Between Vitamin D and Vitamin B12 Levels and Neuropathic Pain in Lipedema
Lipedema is a disease characterized by bilateral abnormal fat deposition in the upper and lower extremities. Pain is a common symptom in lipedema.Vitamin D plays an important role in chronic pain.
- Conditions
- Vitamin D Deficiency, B12 Deficiency Vitamin, Lipedema
- Trial name
- NCT06338059
- Testing
- Vitamin B12 Level
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Lipedema
Effects of Exercise in Patients with Lipedema
Lipedema is a chronic progressive disease characterized by symmetrical, disproportionate swelling of subcutaneous adipose tissue, which is common in women and mostly seen in the lower extremities and to a lesser extent in the…
- Trial name
- NCT06811961
- Testing
- Exercise, Physical activity
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Ilke Keser
Lipedema
Diathermy Effectiveness in Reducing Subcutaneous Adipose Tissue Affected by Lipedema
Diathermy, a therapy that uses deep heat to reach deep tissue layers, is known to induce the breaking down of fatty cells and fibrotic tissue. In lipedema, patients develop fibrosis of their subcutaneous adipose tissue.
- Trial name
- EDRTASAL (NCT05944796)
- Testing
- Diathermy
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Camilo Jose Cela University
Lipedema, Overweight and Obesity
Ketogenic Diet in Women With Lipedema
Lipedema is a chronic fat tissue disorder that usually affects the lower limbs, excluding the feet. Clinical symptoms of lipedema include a noticeable disproportion between the upper and lower body, a tendency to easy bruising…
- Trial name
- NCT07530341
- Testing
- Low carbohydrate high fat (ketogenic) diet with anti-inflammatory properties
- Where
- Poland
- Volunteers
- 121 people
- Sponsor
- Wroclaw Medical University
Lipedema
Evaluation Between Surgical Therapy of Lipedema Compared to Complex Physical Decongestive Therapy (CDT) Alone
The purpose of this study is to determine whether surgical treatment of lipedema (stage I, II or III) using liposuction significantly improves leg pain compared to the use of complex decongestive therapy (CDT).
- Trial name
- LIPLEG (NCT04272827)
- Testing
- Liposuction
- Where
- 12 sites in Germany
- Volunteers
- 450 people
- Sponsor
- Hautklinik Darmstadt
Lipedema
Validity and Reliability of the 2-Minute Step Test in Patients With Lipedema
Lipedema is a chronic, progressive adipose tissue disorder that predominantly affects women and is characterized by symmetric, disproportionate subcutaneous fat accumulation in the lower extremities, pain, tenderness, and easy…
- Trial name
- NCT07752017
- Volunteers
- 55 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Dercum's Disease
A Study to Evaluate the Efficacy and Safety of CBL-514 in Participants With Dercum's Disease Lipomas
This Phase 2 study will be an open-label and randomized study to assess the efficacy and safety of CBL-514 in participants with Dercum's Disease lipomas.
- Trial name
- NCT05387733
- Testing
- 10 mg CBL-514 per injection, 15 mg CBL-514 per injection
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Caliway Biopharmaceuticals Co., Ltd.
Lipedema
Comparison of Complete Decongestive Therapy With Intermittent Pneumatic Compression for Treatment of Lipedema
Lipedema is a chronic, progressive and hereditary adipose tissue disorder characterized by an abnormal increase of subcutaneous adipose tissue, especially in the lower extremities.
- Trial name
- NCT03924999
- Testing
- Combined decongestive treatment (CDT) & Combined exercise, Intermittent pneumatic compression & Combined exercise, Combined exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people
- Sponsor
- Hitit University
Lipedema
Abdominal and Lower Extremity Adipose Tissue Elasticity in Patients With Lipedema
Lipedema is a chronic disorder characterized by abnormal bilateral fat deposition in the extremities, predominantly affecting women and typically beginning at puberty. The trunk, hands, and feet are usually spared.
- Trial name
- NCT07536646
- Testing
- Shearwave elastography
- Where
- Turkey (Türkiye)
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Lipedema
The Effect of Mediterranean Diet on Pain Level and Biochemical Parameters in Women With Lipedema
Objective: To evaluate the effects of a 3-month Mediterranean diet-based intervention on anthropometric and metabolic outcomes, pain and central sensitisation-related symptoms in women with lipedema.
- Trial name
- NCT07853833
- Testing
- Mediterranean Diet-Based Nutritional Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people
- Sponsor
- Baskent University
Lipedema
Effects of Intermittent Pneumatic Compression Therapy on Tissue Volume, Pain, and Quality of Life in Lipedema
Lipedema is an inflammatory and painful disease of subcutaneous adipose tissue (SAT) in women that is associated with vein disease and lymphedema. There is controversy on whether there is edema in lipedema.
- Trial name
- NCT06549738
- Testing
- Intermittent pneumatic compression therapy
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Lympha Press
Lipoedema, Obesity
Physical Condition in Lipedema and Obesity
The diagnosis of lipoedema and obesity are often mixed up, unclear stated and often there is a misdiagnosis. The primary aim is to investigate whether there is a difference in muscle strength between women with lipedema and women…
- Trial name
- NCT01759004
- Testing
- volume, muscle strength, physical condition, BMI
- Where
- Netherlands
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Nij Smellinghe Hosptial
Lipedema
Proof of Concept, Randomized, and Crossover Study, to Assess the Effectiveness of Two Types of Compression Garments in Lipedema
The goal of this prospective randomized crossover experimental study is to assess the effectiveness and tolerance of circular and flat fabric garments in stabilizing lower-limb volume in lipedema.
- Trial name
- LipeGar (NCT06964828)
- Testing
- Flat-knitted compression garment
- Where
- Spain
- Volunteers
- 34 people
- Sponsor
- Isabel Forner-Cordero, MD, PhD
Lipedema, Obesity & Overweight
Ultrasonographic Evaluation and Pedobarographic Correlation of Lower Extremity Muscles in Lipedema Patients
The primary aim of this study is to evaluate the lower extremity muscle structure, lower extremity alignment, and foot posture in lipedema; secondly, to reveal the chain relationship and biomechanical problems that may be…
- Trial name
- PODUSG (NCT07724483)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Marmara University
Lower-Limb Lipedema, Lipedema
"Effect of Endermologie-Assisted Physiotherapy on Edema, Pain, and Functional Recovery After Liposuction for Lower-Limb Lipedema"
Lipedema is a chronic condition that mainly affects women and causes abnormal fat accumulation, pain, heaviness, tenderness, swelling, and difficulty with movement, especially in the lower limbs.
- Trial name
- NCT07618065
- Testing
- Endermologie-Assisted Physiotherapy, Standard Postoperative Physiotherapy
- Where
- 2 sites in Egypt
- Volunteers
- 88 people
- Sponsor
- Cairo University
Lipedema
Visualizing Vascular Mechanisms of Lipedema
This work will address clinical unmet needs for patients with lipedema using advanced magnetic resonance imaging (MRI) methods, in sequence with portable clinical tools, by testing fundamental hypotheses regarding potential…
- Trial name
- VMP (NCT05464927)
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Virginia