FibromyalgiaNCT07791134
The Effect of Connective Tissue Massage on Pressure Pain Threshold in Fibromyalgia
A study testing Connective Tissue Massage in people with Fibromyalgia and PRESSURE PAIN THRESHOLD, run by Ankara Yildirim Beyazıt University at 1 site in Turkey (Türkiye).
Trial summary
The aim of this randomized controlled study is to investigate the immediate effect of connective tissue massage (CTM) on the pressure pain threshold (PPT) in women with fibromyalgia. Read more about this study
- Who is it for?
- Ages 18 to 65 years, women only
- Conditions the study is for
- Fibromyalgia, PRESSURE PAIN THRESHOLD
- What is being tested?
- Connective Tissue Massage
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 58 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 1 Sep 2026to Apr 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- Women only
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Having a diagnosis of FM
- Being a woman between the ages of 18 and 65
- Being willing to participate in the study
Who cannot join
- Diagnosed additional neurological, infectious, and other inflammatory rheumatic diseases; uncontrolled endocrine and/or autoimmune diseases
- Severe psychiatric disorders
- Pregnancy or breastfeeding
- Malignancy
- Presence of acute inflammation, open wounds, or erythema in the massage areas
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Turkey (Türkiye)1 site, 1 recruiting
- Recruiting
Gazi Mustafa Kemal Occupational and Environmental Diseases Hospital
Ankara, 06560
Nuriye Kayalı Şendur, +90 312 212 66 66, ankaradhs7@saglik.gov.tr
About this study
Official title: Investigation of the Immediate Effect of Connective Tissue Massage on Pressure Pain Threshold in Fibromyalgia
The aim of this randomized controlled study is to investigate the immediate effect of connective tissue massage (CTM) on the pressure pain threshold (PPT) in women with fibromyalgia.
- Conditions
- Fibromyalgia, PRESSURE PAIN THRESHOLD
- Being tested
- Connective Tissue Massage
- Medical subject headings
- Fibromyalgia
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Connective Tissue MassageOther
Single-session CTM application for the entire back
| Study group | Role | What they receive |
|---|---|---|
| Control Group | No intervention | Not described |
| CTM Group | Experimental | Not described Receives: Other: Connective Tissue Massage |
What is being measured
The primary outcome is the main question the study is designed to answer.
Measurement of pressure pain threshold
PPT will be determined using a handheld digital algometer with a 1 cm² probe. Measurements will be taken bilaterally at three points: the trapezius, lumbar region, and pretibial area. In the control group, the first measurement will be taken, followed by a second measurement approximately 20 minutes later. In the CTM group, measurements will be taken before and after the CTM procedure.
Measured: Baseline and 20 minutes post-intervention
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted27 Aug 2026
- Study start1 Sep 2026
- Primary completionOct 2026 (estimated)
- Study completionApr 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for FibromyalgiaStudies of the same condition, open and under way.
- More trials run by Ankara Yildirim Beyazıt UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 58 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Ankara Yildirim Beyazıt University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Beyza Avcı, Ankara Yildirim Beyazıt University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07791134
- Sponsor's protocol ID
- 2026/6-30
- Status last verified
- Sep 2026
- First submitted
- 25 Aug 2026
- Last updated
- 23 Sep 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 23 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Investigation of the Immediate Effect of Connective Tissue Massage on Pressure Pain Threshold in Fibromyalgia
- ClinicalTrials.gov ID
- NCT07791134
- Acronym / sponsor ID
- 2026/6-30
- Conditions
- Fibromyalgia, PRESSURE PAIN THRESHOLD
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 58 participants (estimated)
- Lead sponsor
- Ankara Yildirim Beyazıt UniversityUniversity, hospital or other
- Study start
- 1 Sep 2026 (actual)
- Primary completion
- Oct 2026 (estimated)
- Study completion
- Apr 2027 (estimated)
- First posted
- 27 Aug 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aim of this randomized controlled study is to investigate the immediate effect of connective tissue massage (CTM) on the pressure pain threshold (PPT) in women with fibromyalgia.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Control Group | No intervention | – |
| CTM Group | Experimental | Other: Connective Tissue Massage |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- Female only
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- Having a diagnosis of FM
- Being a woman between the ages of 18 and 65
- Being willing to participate in the study
Key exclusion criteria (5 listed)
- Diagnosed additional neurological, infectious, and other inflammatory rheumatic diseases; uncontrolled endocrine and/or autoimmune diseases
- Severe psychiatric disorders
- Pregnancy or breastfeeding
- Malignancy
- Presence of acute inflammation, open wounds, or erythema in the massage areas
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Connective Tissue MassageSingle-session CTM application for the entire back | Other | CTM Group |
Primary outcome
Measurement of pressure pain threshold
Time frame: Baseline and 20 minutes post-intervention
PPT will be determined using a handheld digital algometer with a 1 cm² probe. Measurements will be taken bilaterally at three points: the trapezius, lumbar region, and pretibial area. In the control group, the first measurement will be taken, followed by a second measurement approximately 20 minutes later. In the CTM group, measurements will be taken before and after the CTM procedure.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 23 Sep 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Gazi Mustafa Kemal Occupational and Environmental Diseases Hospital
Ankara, Turkey (Türkiye)
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Connective Tissue Massage in people with Fibromyalgia and PRESSURE PAIN THRESHOLD, run by Ankara Yildirim Beyazıt University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 23 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Each site lists its own contact: choose the nearest one under Trial locations. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Measurement of pressure pain threshold (time frame: Baseline and 20 minutes post-intervention). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 23 Sep 2026.