Wound HealingNCT07793851
Fucoidan(Seaweed) Based Gel Around Osseous Defects
An observational study of Wound Healing and Bone Regeneration, run by Krishnadevaraya College of Dental Sciences & Hospital at 1 site in India.
Trial summary
The current study is a prospective case series study to evaluate the effect of Fucoidan gel around osseous defects to assess the wound healing and bone regeneration Read more about this study
- Who is it for?
- Ages 25 to 55 years, women onlyHealthy volunteers can take part
- Conditions the study is for
- Wound Healing, Bone Regeneration
- How many people
- 5 participants
- Where
- 1 siteIndia
- Study dates
- 11 Jun 2025to 30 Jun 2026
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 25 to 55 years
- Women only
- Healthy volunteers accepted
- Adult
Study population: All the patients who meet the eligible criteria will undergo Scaling and root planning (SRP) as a part of Phase I therapy. Patients with ≥6mm probing sites will undergo surgical therapy, patients presenting with different osseous defects will be treated with Fucoidan gel. A total of 5 samples will be allotted to different defects
Who may be able to join
- Systemically healthy patients between 25 to 55 years.
- Stage II/III and Grade B periodontitis patient.
- Osseous defects (intra bony defects, compromised bone support and around dental implants)
Who cannot join
- Patients with systemic diseases.
- Smokers.
- Patients under anticoagulant therapy.
- Patients under bisphosphonates.
- Pregnant and lactating women
Trial locations and contacts
1 site in 1 country.
India1 site
Krishnadevaraya college of dental sciences and hospital
Bangalore, Karnataka, 562157
About this study
Official title: Clinical And Radiographic Evaluation Of Fucoidan Gel In Patients With Osseous Defects- A Case Series
The current study is a prospective case series study to evaluate the effect of Fucoidan gel around osseous defects to assess the wound healing and bone regeneration
Read the detailed description
Five healthy individuals satisfying the inclusion and exclusion criteria were recruited for the study. A detailed, thorough medical and dental history was obtained and each patient was subjected to comprehensive clinical and radiological examination. All patients were informed about the nature of the study, procedure involved, potential benefits and risks associated with procedure and written informed consent were obtained from all patients. All the patients underwent scaling and root planning.
- Conditions
- Wound Healing, Bone Regeneration
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| placement of fucoidan gel in osseous defects | Drug: Fucoidan extracted from F. Vesiculosus placement of fucoidan gel in osseous defects such as intrabony defect, compromised bone support |
What is being measured
The primary outcome is the main question the study is designed to answer.
wound healing following placement of fucoidan gel
Landry, Turnbull and Howley wound healing index
Measured: 7th day,14th day, 21st day, 1 month, at 3months and 6 months
Secondary outcomes (1)
crestal bone level
using RVG with 1 mm grid
Measured: baseline, 3month and 6 month
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted31 Aug 2026
- Study start11 Jun 2025
- Primary completion11 Oct 2025
- Study completion30 Jun 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Wound HealingStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Prospective
- Enrolment
- 5 participants (actual)
Sponsor and investigators
- Lead sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- DR .Prabhuji MLV, MDS, Study director, Krishnadevaraya college of dental sciences and hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07793851
- Sponsor's protocol ID
- KCDSHEC/IP/2025/44
- Status last verified
- Aug 2026
- First submitted
- 24 Aug 2026
- Last updated
- 31 Aug 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 31 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Clinical And Radiographic Evaluation Of Fucoidan Gel In Patients With Osseous Defects- A Case Series
- ClinicalTrials.gov ID
- NCT07793851
- Acronym / sponsor ID
- KCDSHEC/IP/2025/44
- Conditions
- Wound Healing, Bone Regeneration
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 5 participants (actual)
- Lead sponsor
- Krishnadevaraya College of Dental Sciences & HospitalUniversity, hospital or other
- Study start
- 11 Jun 2025 (actual)
- Primary completion
- 11 Oct 2025 (actual)
- Study completion
- 30 Jun 2026 (actual)
- First posted
- 31 Aug 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The current study is a prospective case series study to evaluate the effect of Fucoidan gel around osseous defects to assess the wound healing and bone regeneration
Detailed description
Five healthy individuals satisfying the inclusion and exclusion criteria were recruited for the study. A detailed, thorough medical and dental history was obtained and each patient was subjected to comprehensive clinical and radiological examination. All patients were informed about the nature of the study, procedure involved, potential benefits and risks associated with procedure and written informed consent were obtained from all patients. All the patients underwent scaling and root planning.
Study design
- Observational model
- Other
- Time perspective
- Prospective
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| placement of fucoidan gel in osseous defects | – | –Drug: Fucoidan extracted from F. Vesiculosus placement of fucoidan gel in osseous defects such as intrabony defect, compromised bone support |
Who may qualify
- Ages
- 25 to 55 years
- Sex
- Female only
- Healthy volunteers
- Accepted
- Age groups
- Adult
- Study population
- All the patients who meet the eligible criteria will undergo Scaling and root planning (SRP) as a part of Phase I therapy. Patients with ≥6mm probing sites will undergo surgical therapy, patients presenting with different osseous defects will be treated with Fucoidan gel. A total of 5 samples will be allotted to different defects
Key inclusion criteria (3 listed)
- Systemically healthy patients between 25 to 55 years.
- Stage II/III and Grade B periodontitis patient.
- Osseous defects (intra bony defects, compromised bone support and around dental implants)
Key exclusion criteria (5 listed)
- Patients with systemic diseases.
- Smokers.
- Patients under anticoagulant therapy.
- Patients under bisphosphonates.
- Pregnant and lactating women
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
wound healing following placement of fucoidan gel
Time frame: 7th day,14th day, 21st day, 1 month, at 3months and 6 months
Landry, Turnbull and Howley wound healing index
1 secondary outcome
crestal bone level
Time frame: baseline, 3month and 6 month
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 31 Aug 2026.
- Individual participant dataSharing planned: Undecided
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
DR .Prabhuji MLV, MDS study director
Krishnadevaraya college of dental sciences and hospital
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Wound Healing and Bone Regeneration, run by Krishnadevaraya College of Dental Sciences & Hospital at 1 site in India.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 31 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in India. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
wound healing following placement of fucoidan gel (time frame: 7th day,14th day, 21st day, 1 month, at 3months and 6 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 31 Aug 2026.