Uterine AnteflexionFLEXIMIX3NCT07803627
Changes in the Angle of Uterine Flexion as the Bladder Fills
A study testing Ultrasonography, Pelvic in people with Uterine Anteflexion, run by University Hospital, Brest at 1 site in France.
Trial summary
The goal of this clinical trial is to evaluate how bladder filling affects the uterine flexion angle in adult nulliparous women with a uterine flexion angle <90° when the bladder is empty. Read more about this study
- Who is it for?
- Ages 18 years and older, women onlyHealthy volunteers can take part
- Conditions the study is for
- Uterine Anteflexion
- What is being tested?
- Ultrasonography, Pelvic
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 30 participants
- Where
- 1 siteFrance
- Study dates
- 15 Sep 2026to 15 Mar 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- Women only
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Adult woman
- Nulliparous
- Registered with a social security scheme
- Uterine flexion angle < 90°, empty bladder
Who cannot join
- Pregnant woman
- Woman wishing to become pregnant and currently trying to conceive
- Primary amenorrhoea
- Menopause
- History of surgical termination of pregnancy
- History of medical termination of pregnancy
Show all 11Show fewer
- History of hysterectomy
- History of conisation
- Absence of the uterus
- Symptoms of urinary tract infection (gross haematuria, burning on urination, frequent urination)
- Under legal guardianship (curatorship, trusteeship)
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
France1 site
Benoit CHIRON
Le Relecq-Kerhuon, 29480
Benoit CHIRON, MD, benoitchiron@yahoo.fr
About this study
Official title: Prospective Study of the Changes in the Angle of Uterine Flexion as the Bladder Fills
The goal of this clinical trial is to evaluate how bladder filling affects the uterine flexion angle in adult nulliparous women with a uterine flexion angle <90° when the bladder is empty.
The main questions it aims to answer are:
How does the uterine flexion angle change as bladder volume increases? What bladder volume is needed to obtain a uterine flexion angle >90°?
Participants will:
Drink 600 mL of water following a standardized protocol. Undergo repeated suprapubic ultrasound measurements of bladder volume and uterine flexion angle.
Remain under observation until urination or for a maximum of 4 hours. No comparison group is included in this study.
- Conditions
- Uterine Anteflexion
- Being tested
- Ultrasonography, Pelvic
- Keywords
- Uterine anteflexion, Nulliparous women, Bladder filling, Ultrasound measurements
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Ultrasonography, PelvicProcedure or surgery
Repeated ultrasound measurements, alternating between volume and angle of flexion, immediately following a hydration protocol and then bladder emptying.
| Study group | Role | What they receive |
|---|---|---|
| Ultrasonography pelvic | Other | Repeated ultrasound measurements, alternating between volume and angle of flexion, immediately following a hydration protocol and then bladder emptying. Receives: Procedure: Ultrasonography, Pelvic |
What is being measured
The primary outcome is the main question the study is designed to answer.
Uterine Flexion Angle Measured at Different Bladder Volumes in Nulliparous Women With an Anteverted Uterus and Baseline Uterine Flexion Angle <90°
The relationship between bladder volume and the angle of uterine flexion, as determined from repeated ultrasound measurements in the participants.
Measured: 4 hours
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted3 Sep 2026
- Study start15 Sep 2026 (estimated)
- Primary completion15 Mar 2027 (estimated)
- Study completion15 Mar 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Uterine AnteflexionStudies of the same condition, open and under way.
- More trials run by University Hospital, BrestThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 30 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University Hospital, Brest
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07803627
- Sponsor's protocol ID
- 29BRC25.0436
- Acronym
- FLEXIMIX3
- Status last verified
- Sep 2026
- First submitted
- 28 Aug 2026
- Last updated
- 3 Sep 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: All collected data that underlie results in a publication
Study at a glance
From the registry record, last updated by the sponsor on 3 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Prospective Study of the Changes in the Angle of Uterine Flexion as the Bladder Fills
- ClinicalTrials.gov ID
- NCT07803627
- Acronym / sponsor ID
- FLEXIMIX3 / 29BRC25.0436
- Conditions
- Uterine Anteflexion
- Keywords
- Uterine anteflexion, Nulliparous women, Bladder filling, Ultrasound measurements
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 30 participants (estimated)
- Lead sponsor
- University Hospital, BrestUniversity, hospital or other
- Study start
- 15 Sep 2026 (estimated)
- Primary completion
- 15 Mar 2027 (estimated)
- Study completion
- 15 Mar 2027 (estimated)
- First posted
- 3 Sep 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this clinical trial is to evaluate how bladder filling affects the uterine flexion angle in adult nulliparous women with a uterine flexion angle <90° when the bladder is empty.
The main questions it aims to answer are:
How does the uterine flexion angle change as bladder volume increases? What bladder volume is needed to obtain a uterine flexion angle >90°?
Participants will:
Drink 600 mL of water following a standardized protocol. Undergo repeated suprapubic ultrasound measurements of bladder volume and uterine flexion angle.
Remain under observation until urination or for a maximum of 4 hours. No comparison group is included in this study.
Study design
- Primary purpose
- Other
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Ultrasonography pelvic | Other | Procedure: Ultrasonography, PelvicRepeated ultrasound measurements, alternating between volume and angle of flexion, immediately following a hydration protocol and then bladder emptying. |
Who may qualify
- Ages
- 18 years and older
- Sex
- Female only
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- Adult woman
- Nulliparous
- Registered with a social security scheme
- Uterine flexion angle < 90°, empty bladder
Key exclusion criteria (11 listed)
- Pregnant woman
- Woman wishing to become pregnant and currently trying to conceive
- Primary amenorrhoea
- Menopause
- History of surgical termination of pregnancy
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Ultrasonography, PelvicRepeated ultrasound measurements, alternating between volume and angle of flexion, immediately following a hydration protocol and then bladder emptying. | Procedure or surgery | Ultrasonography pelvic |
Primary outcome
Uterine Flexion Angle Measured at Different Bladder Volumes in Nulliparous Women With an Anteverted Uterus and Baseline Uterine Flexion Angle <90°
Time frame: 4 hours
The relationship between bladder volume and the angle of uterine flexion, as determined from repeated ultrasound measurements in the participants.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 3 Sep 2026.
- Individual participant dataSharing planned: Yes. All collected data that underlie results in a publication
Related trials for Uterine Anteflexion
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Ultrasonography, Pelvic in people with Uterine Anteflexion, run by University Hospital, Brest at 1 site in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 11 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 3 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Benoit CHIRON, MD (02 98 40 19 21 ext. +33, benoitchiron@yahoo.fr), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Uterine Flexion Angle Measured at Different Bladder Volumes in Nulliparous Women With an Anteverted Uterus and Baseline Uterine Flexion Angle <90° (time frame: 4 hours). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 3 Sep 2026.