Research institution
University Hospital, Brest Clinical Trials
Studies where University Hospital, Brest is the lead sponsor: what is enrolling now, by phase, condition and country.
In numbers
Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.
Open to volunteers
All 110Chronic Respiratory Diseases
Interest of Cryotherapy in Reducing Pain During Radial Arterial Blood Sampling
Arterial puncture for blood gas analysis is a diagnostic procedure used to assess arterial blood gases and monitor a patient's oxygenation status.
- Trial name
- HOURRA (NCT07408011)
- Testing
- Apllication of medical device ice pack, Apllication of cream
- Where
- 2 sites in France
- Volunteers
- 258 people
- Sponsor
- University Hospital, Brest
Healthy Subjects
Functional Regulation of Autoreactive Lymphocytes: Phenotypic and Transcriptomic Investigations in Healthy Subjects
The goal of this study is to study the autoreactive lymphocytes in healthy volunteers. More specifically, this research aims to identify what distinguishes the autoreactive lymphocytes found in healthy individuals from those…
- Trial name
- REFLEX (NCT07898826)
- Testing
- Blood sampling at D0, Blood sampling at D0, M12 and M24
- Where
- France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Stereotactic Body Radiotherapy, 68Ga-MAA
Functional Lung Avoidance Planning Guided by Lung Perfusion PET/CT Versus Anatomical Planning for Lung Stereotactic Body Radiotherapy
Stereotactic body radiotherapy (SBRT) has an increasing role in the treatment of both primary and secondary lung tumors. However, lung SBRT remains associated with significant radiation induced lung injury (RILI).
- Conditions
- Stereotactic Body Radiotherapy, 68Ga-MAA, Lung Cancer (Diagnosis)
- Trial name
- Pegasus 2 (NCT07289646)
- Testing
- Conventional anatomical planning radiotherapy, Functional Lung avoidance planning
- Where
- 2 sites in France
- Volunteers
- 418 people
- Sponsor
- University Hospital, Brest
Addiction, Alcohol
Evaluation of the Implementation of a Parenting Program in Parents With Children Aged 4 to 12 Years and One Parent With an Alcohol Use Disorders
Alcohol use disorders are a major public health problem in Europe. The average prevalence of Alcohol Use Disorders (AUD) in the general population is 7.5%, although there are large variations between countries.
- Trial name
- APPROCHILD (NCT05490589)
- Testing
- EQUIPE Program
- Where
- France
- Volunteers
- 90 people
- Sponsor
- University Hospital, Brest
Cancer
Understanding and Anticipating Therapeutic and ADverse Responses in Anti-cancer Immune Checkpoint Inhibition Towards a Better Therapeutic Management of Patients
The goal of this observational study is to explore the value of blood biomarkers for the purpose of predicting irAE development in cancer patients treated with immune checkpoint inihibitors (ICI) alone or in combination with…
- Trial name
- TADIG-P (NCT05973344)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Brest
Chronic Low Back Pain
Assessment of Pain Perception and the Impact of Central Sensitization on Biopsychosocial Manifestations During Physical Activity in Patients With Chronic Low Back Pain
The goal of this prospective observational study is to evaluate changes in cognitive and behavioural markers associated with central sensitisation between the start and end of an exercise retraining programme on an exercise bike…
- Trial name
- BASICS (NCT07818551)
- Testing
- Exercise rehabilitation on an ergocycle
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Brest
Uterine Anteflexion
Changes in the Angle of Uterine Flexion as the Bladder Fills
The goal of this clinical trial is to evaluate how bladder filling affects the uterine flexion angle in adult nulliparous women with a uterine flexion angle <90° when the bladder is empty.
- Trial name
- FLEXIMIX3 (NCT07803627)
- Testing
- Ultrasonography, Pelvic
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Polymyalgia Rheumatica (PMR)
Justification And Evaluation of Baricitinib Plus Corticosteroids Versus corticosteroiDs Alone in pOlymyalgia RhEumatica
Polymyalgia rheumatic (PMR) is an inflammatory rheumatic disease affecting the elderly. The diagnosis is based on established ACR/EULAR classification criteria.
- Trial name
- JADORE-BARI (NCT07279688)
- Testing
- Baricitinib 4 MG Oral Tablet, Baricitinib 2 MG Oral Tablet
- Where
- 23 sites in France
- Volunteers
- 140 people
- Sponsor
- University Hospital, Brest
Attention Deficit Disorder With Hyperactivity (ADHD), Substance Use Disorder (SUD)
Unified Junction of Care, Integrated Treatments and Team Coordination for ADHD in Prison Settings With Substance Use Disorder
Substance use disorders (SUD) and attention deficit disorder with or without hyperactivity (ADHD) are frequently co-morbid, particularly among people under court supervision.
- Trial name
- JUSTICE-TDAH (NCT07487155)
- Testing
- Workshop
- Where
- France
- Volunteers
- 39 people
- Sponsor
- University Hospital, Brest
Head & Neck Squamous Cell Carcinoma
Diagnostic Performance Of 4D Dynamic LAFOV FDG-PET Acquisition for Differentiation of Residual Disease and Post-radiation Inflammation in Head Neck SCC Treated by Radiotherapy.
This multicenter prospective observational study will evaluate the value of dynamic FDG-PET LAFOV imaging during the initial therapeutic assessment of a head and neck cancer 3 months after completion of curative radiotherapy.
- Trial name
- POLARIS (NCT07417605)
- Where
- 3 sites in France
- Volunteers
- 180 people
- Sponsor
- University Hospital, Brest