Chest TraumaNCT07812038
Predictive Value of Chest Trauma Score , Revised Trauma Score , and Glasgow Coma Scale in Patients Presenting With Chest Trauma at Assiut University Emergency Unit.
An observational study of Chest Trauma, run by Assiut University.
Trial summary
Thoracic trauma is a critical clinical entity and a major global public health burden, representing the second most frequently occurring unintentional traumatic injury and the third most common cause of death-following head and abdominal injuries-in patients with polytrauma. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Chest Trauma
- How many people
- 100 participants
- Where
- No sites listed yet
- Study dates
- Oct 2026to Dec 2027
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Patients with documented clinical or radiological evidence of chest injury (e.g., rib fractures, pulmonary contusion, pneumothorax, or hemothorax confirmed via X-ray, chest CT, or FAST).
Who may be able to join
- Age threshold: Patients aged 18 years and older (pediatric physiology requires entirely different trauma scoring systems).
- Mechanism of injury: Patients presenting with acute blunt or penetrating thoracic trauma or both.
- Diagnostic confirmation: Patients with documented clinical or radiological evidence of chest injury (e.g., rib fractures, pulmonary contusion, pneumothorax, or hemothorax confirmed via X-ray, chest CT, or FAST).
- Time of presentation: Patients presenting directly to the emergency department within 24 hours of the trauma incident.
Who cannot join
- Inter-facility transfers: Exclude patients transferred from other hospitals. If they were already intubated, given sedatives, or resuscitated elsewhere, their admission scores will be artificially altered and will not reflect their true initial presentation.
- Dead on Arrival (DOA): Patients who arrive in cardiac arrest or expire before the initial primary survey and scoring can be completed.
- Isolated severe head trauma or massive burns: Patients whose clinical picture and need for intubation are overwhelmingly driven by severe traumatic brain injury (e.g., GCS < 8 from head injury alone without significant chest trauma) or massive burns, rather than the thoracic injury.
- Severe chronic cardiopulmonary disease: patients with known end-stage COPD, severe baseline heart failure, or those on home oxygen. Their baseline hypoxia or need for ventilation can confound the trauma scores' predictive value.
- Incomplete data: Patients whose medical records are missing the crucial variables needed to calculate the GCS, RTS, or CTS upon arrival.
About this study
Thoracic trauma is a critical clinical entity and a major global public health burden, representing the second most frequently occurring unintentional traumatic injury and the third most common cause of death-following head and abdominal injuries-in patients with polytrauma. It places a substantial demand on emergency departments and directly accounts for 20% to 25% of all trauma-related fatalities worldwide(1). The severity of these injuries is underscored by persistently high mortality rates, which can reach up to 60% in cases of severe blunt chest trauma depending on the healthcare setting. Recent epidemiological data indicates that among potentially preventable trauma deaths, thoracic injuries represent up to 41%, with blunt mechanisms such as motor vehicle collisions acting as the primary driver (accounting for 80% to 92% of cases)(2). Given this significant risk profile, rapid and accurate clinical triage is vital. Current evidence consistently demonstrates that early recognition, protocolized multidisciplinary management, and the timely provision of definitive interventions at dedicated trauma centers are essential to decreasing morbidity and significantly reducing preventable trauma mortality(3).Effective initial assessment in the ED relies heavily on validated trauma scoring systems. GCS is the most universally utilized tool for evaluating a patient's level of consciousness, calculating a score between 3 and 15 based on three physiological parameters: eye opening, verbal response, and motor response. RTS is a broader physiological scoring system combining the GCS, systolic blood pressure, and respiratory rate. CTS is a specific, targeted assessment tool designed to quantify the severity of thoracic injuries.
- Conditions
- Chest Trauma
- Medical subject headings
- Thoracic Injuries
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| study group | Patients with documented clinical or radiological evidence of chest injury (e.g., rib fractures, pulmonary contusion, pneumothorax, or hemothorax confirmed via X-ray, chest CT, or FAST |
What is being measured
The primary outcome is the main question the study is designed to answer.
diagnositic acuracy of the Glasgow Coma Scale (GCS), in cases of thoracic trauma.
Measured: baseline
diagnostic acuracy of the Revised Trauma Score (RTS) in cases of thoracic trauma.
Measured: baseline
diagnostic acuracy of the Chest Trauma Score (CTS) in cases of thoracic trauma.
Measured: baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted10 Sep 2026
- Study startOct 2026 (estimated)
- Primary completionOct 2027 (estimated)
- Study completionDec 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Chest TraumaStudies of the same condition, open and under way.
- More trials run by Assiut UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 100 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Assiut University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Tarek Ragaey Ali Sayed, Assiut University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07812038
- Sponsor's protocol ID
- CTS ,RTS& GCS
- Status last verified
- Sep 2026
- First submitted
- 4 Sep 2026
- Last updated
- 10 Sep 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 10 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Predictive Value of Chest Trauma Score , Revised Trauma Score , and Glasgow Coma Scale in Patients Presenting With Chest Trauma at Assiut University Emergency Unit.
- ClinicalTrials.gov ID
- NCT07812038
- Acronym / sponsor ID
- CTS ,RTS& GCS
- Conditions
- Chest Trauma
- Study type
- Observational
- Recruitment status
- Not yet recruiting
- Enrolment
- 100 participants (estimated)
- Lead sponsor
- Assiut UniversityUniversity, hospital or other
- Study start
- Oct 2026 (estimated)
- Primary completion
- Oct 2027 (estimated)
- Study completion
- Dec 2027 (estimated)
- First posted
- 10 Sep 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Thoracic trauma is a critical clinical entity and a major global public health burden, representing the second most frequently occurring unintentional traumatic injury and the third most common cause of death-following head and abdominal injuries-in patients with polytrauma. It places a substantial demand on emergency departments and directly accounts for 20% to 25% of all trauma-related fatalities worldwide(1). The severity of these injuries is underscored by persistently high mortality rates, which can reach up to 60% in cases of severe blunt chest trauma depending on the healthcare setting. Recent epidemiological data indicates that among potentially preventable trauma deaths, thoracic injuries represent up to 41%, with blunt mechanisms such as motor vehicle collisions acting as the primary driver (accounting for 80% to 92% of cases)(2). Given this significant risk profile, rapid and accurate clinical triage is vital. Current evidence consistently demonstrates that early recognition, protocolized multidisciplinary management, and the timely provision of definitive interventions at dedicated trauma centers are essential to decreasing morbidity and significantly reducing preventable trauma mortality(3).Effective initial assessment in the ED relies heavily on validated trauma scoring systems. GCS is the most universally utilized tool for evaluating a patient's level of consciousness, calculating a score between 3 and 15 based on three physiological parameters: eye opening, verbal response, and motor response. RTS is a broader physiological scoring system combining the GCS, systolic blood pressure, and respiratory rate. CTS is a specific, targeted assessment tool designed to quantify the severity of thoracic injuries.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| study group | – | –Patients with documented clinical or radiological evidence of chest injury (e.g., rib fractures, pulmonary contusion, pneumothorax, or hemothorax confirmed via X-ray, chest CT, or FAST |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Patients with documented clinical or radiological evidence of chest injury (e.g., rib fractures, pulmonary contusion, pneumothorax, or hemothorax confirmed via X-ray, chest CT, or FAST).
Key inclusion criteria (4 listed)
- Age threshold: Patients aged 18 years and older (pediatric physiology requires entirely different trauma scoring systems).
- Mechanism of injury: Patients presenting with acute blunt or penetrating thoracic trauma or both.
- Diagnostic confirmation: Patients with documented clinical or radiological evidence of chest injury (e.g., rib fractures, pulmonary contusion, pneumothorax, or hemothorax confirmed via X-ray, chest CT, or FAST).
- Time of presentation: Patients presenting directly to the emergency department within 24 hours of the trauma incident.
Key exclusion criteria (5 listed)
- Inter-facility transfers: Exclude patients transferred from other hospitals. If they were already intubated, given sedatives, or resuscitated elsewhere, their admission scores will be artificially altered and will not reflect their true initial presentation.
- Dead on Arrival (DOA): Patients who arrive in cardiac arrest or expire before the initial primary survey and scoring can be completed.
- Isolated severe head trauma or massive burns: Patients whose clinical picture and need for intubation are overwhelmingly driven by severe traumatic brain injury (e.g., GCS < 8 from head injury alone without significant chest trauma) or massive burns, rather than the thoracic injury.
- Severe chronic cardiopulmonary disease: patients with known end-stage COPD, severe baseline heart failure, or those on home oxygen. Their baseline hypoxia or need for ventilation can confound the trauma scores' predictive value.
- Incomplete data: Patients whose medical records are missing the crucial variables needed to calculate the GCS, RTS, or CTS upon arrival.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
diagnositic acuracy of the Glasgow Coma Scale (GCS), in cases of thoracic trauma.
Time frame: baseline
diagnostic acuracy of the Revised Trauma Score (RTS) in cases of thoracic trauma.
Time frame: baseline
diagnostic acuracy of the Chest Trauma Score (CTS) in cases of thoracic trauma.
Time frame: baseline
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 10 Sep 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
The record lists no contact. Use the official record to reach the sponsor.
Questions about this trial
What is this clinical trial studying?
An observational study of Chest Trauma, run by Assiut University.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 10 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
diagnositic acuracy of the Glasgow Coma Scale (GCS), in cases of thoracic trauma. (time frame: baseline). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 10 Sep 2026.