Advancing Ethical Goals In Society Trial

Study at a glance

From the registry record, last updated by the sponsor on 17 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.

Official title

ACP Educator Video Program to Promote Goal-Concordant Care in Older Patients and Those With Alzheimer's Disease and Related Dementias: Advancing Ethical Goals In Society (AEGIS)

ClinicalTrials.gov ID

NCT07824245

Acronym / sponsor ID

AEGIS / 00006552

Conditions

Advance Care Planning, Dementia, Alzheimer's Disease

Keywords

ADRD, dissemination and implementation science, Goal Concordant Care

Study type

Interventional

Recruitment status

Not yet recruiting

Enrolment

12,174 participants (estimated)

Lead sponsor

Tufts Medical CenterUniversity, hospital or other

Collaborators

National Institute on Aging (NIA), Dana-Farber Cancer Institute, Emory University, University of Colorado, Denver, Wake Forest University Health Sciences, Trustees of Dartmouth College, Dartmouth-Hitchcock Medical Center, Northern California Institute of Research and Education, Mayo Clinic Arizona ADRC, Feinstein Institute for Medical Research

Study start

1 Mar 2027 (estimated)

Primary completion

1 Mar 2029 (estimated)

Study completion

1 Mar 2031 (estimated)

First posted

17 Sep 2026 (actual)

Results

Not posted in the source record

Clinical summary

The research question as the sponsor registered it. This describes what the study plans to test, not what it found.

Study design

Primary purpose

Health services research

Allocation

Randomised

Intervention model

Parallel groups

Masking

Single blind (outcomes assessor)

Number of arms

2

Model description

Pragmatic, randomized, delayed-start trial with routine care as the control during the first 24 months

Who may qualify

Ages

65 years and older

Sex

All

Healthy volunteers

Not accepted

Age groups

Older adult

Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.

Interventions

Primary outcome

1. Presence of qualifying ACP documentation by the end of Phase 1

   Time frame: From randomization through the end of Phase 1 (24 months).

   This outcome will be the percentage of participants with qualifying ACP documentation. Qualifying ACP documentation is defined as ACP documentation that is newly created or updated during Phase 1.

2. Occurrence of adjudicated goal-concordant care during the last 3 months of life

   Time frame: Final 3 months of life among participants who die during Phase 1, up to 24 months after randomization.

   This outcome is defined to be the percentage of decedents classified as having goal-concordant care.

Results and safety

This study is still under way. Results are not available in the source record yet.

Research links

• Official record on ClinicalTrials.govLast updated by the sponsor 17 Sep 2026.
• Individual participant dataSharing planned: Yes. We will create a deidentified data set that will be preserved and shared. The purpose of creating this is to allow other investigators access to the data to advance inquiry in the field. We share the NIH's goal for sharing data to allow scientists to expedite the translation of research results into knowledge, products, and procedures to improve human health. To this end, we will make study data as widely and freely available as possible while safeguarding the privacy of participants and protecting confidential and proprietary data. Manuscripts will be submitted for publication in high-quality peer-reviewed journals, following NIH Public Access Policy guidelines. We will investigate opportunities for public forums, including those provided by the NIH. We will include a data dictionary for all original and derived data elements, administrative guidance for tool administration, intervention protocol documentation, qualitative coding documentation, as well as all publications using it.

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Referral and contact

AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.

2 sites in 1 country: see every site and its status.