Anterior Knee PainNCT07842913
Hybrid Telerehabilitation for Anterior Knee Pain in Routine Physiotherapy Practice
A study testing Hybrid Telerehabilitation in people with Anterior Knee Pain, run by Farraj Miguel at 2 sites in 2 countries.
Trial summary
This study will examine how hybrid telerehabilitation is used in routine physiotherapy care for adults with anterior knee pain. Approximately 30 participants will be followed for 72 weeks while receiving individualized treatment from their physiotherapist, supported by the moveUP mobile application. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Anterior Knee Pain
- What is being tested?
- Hybrid Telerehabilitation
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 30 participants
- Where
- 2 sitesin 2 countries
- Study dates
- Sep 2026to Dec 2028
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Age 18 years or older.
- Clinical diagnosis of anterior knee pain, including patellofemoral pain, patellar tendinopathy, Hoffa's fat pad syndrome, chondromalacia, or femoropatellar, tibiopatellar, or tibiofemoral osteoarthritis not requiring surgery.
- Access to a smartphone compatible with the moveUP application.
Who cannot join
- Currently awaiting spine or lower-limb surgery.
- Lower-limb surgery or other invasive intervention within the previous two years.
- Joint prosthesis.
- Acute trauma to the trunk or lower limbs, or fracture, dislocation, or other musculoskeletal pathology of the affected lower limb within the previous six months.
- Saphenous nerve neuritis or Ehlers-Danlos syndrome.
- Severe osteoarthritis requiring joint replacement, systemic inflammatory joint disease (including rheumatoid arthritis or gout), or joint infection.
Show all 10Show fewer
- Persistent low back pain lasting three months or longer.
- Vascular, respiratory, or neurological conditions that interfere with participation.
- Cognitive or psychiatric impairment limiting application use or communication.
- Pregnancy.
Trial locations and contacts
2 sites in 2 countries. Contact the study team or a site near you to ask about taking part.
2 sites in 2 countries
Belgium1 site, 1 recruiting
- Recruiting
Private clinics
Brussels
Miguel Farraj, PhD candidate, +32494035113, miguel.farraj@ulb.be
France1 site, 1 recruiting
- Recruiting
Private clinics
Paris
Miguel Farraj, PhD candidate, +32494035113, miguel.farraj@ulb.be
About this study
Official title: Integrating Hybrid Telerehabilitation Into Routine Physiotherapy Practice for Anterior Knee Pain: Protocol for a Real-World Pragmatic Mixed-Methods Study
This study will examine how hybrid telerehabilitation is used in routine physiotherapy care for adults with anterior knee pain. Approximately 30 participants will be followed for 72 weeks while receiving individualized treatment from their physiotherapist, supported by the moveUP mobile application. The application provides prescribed exercises, educational information, communication with the physiotherapist, and progress monitoring.
The study will assess adherence to rehabilitation, pain, knee function, quality of life, psychological factors, and physical activity. It will also explore whether patient adherence and physiotherapist engagement are associated with clinical outcomes. Interviews with patients and healthcare professionals will examine barriers and facilitators to using the platform in routine care.
- Conditions
- Anterior Knee Pain
- Being tested
- Hybrid Telerehabilitation
- Keywords
- Telerehabilitation, Exercise Adherence, Mobile Health, Physiotherapy
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Hybrid TelerehabilitationBehavioural
Hybrid telerehabilitation combining routine physiotherapy with the moveUP mobile application for adults with anterior knee pain. The platform supports individualized exercise prescription, educational modules, patient-physiotherapist communication, and progress monitoring. Exercise selection, frequency, and progression are determined by the treating physiotherapist according to patient needs. Participants are followed for 72 weeks.
| Study group | Role | What they receive |
|---|---|---|
| Hybrid Telerehabilitation | Experimental | Participants receive individualized physiotherapy for anterior knee pain supported by the moveUP mobile application over 72 weeks. Treatment is prescribed and adapted by the treating physiotherapist according to individual patient needs. Receives: Behavioral: Hybrid Telerehabilitation |
What is being measured
The primary outcome is the main question the study is designed to answer.
Exercise Adherence (ATEMPT Score)
Exercise adherence will be assessed using the Adherence to Exercise for Musculoskeletal Pain Tool (ATEMPT). Total scores range from 6 to 30, with higher scores indicating greater adherence.
Measured: Baseline and weeks 6, 12, 18, 24, 36, 48, 60, and 72
Pain Intensity (Visual Analog Scale)
Pain intensity will be measured using a 0-100 mm Visual Analog Scale (VAS), where 0 indicates no pain and 100 indicates the worst pain imaginable. Higher scores indicate greater pain intensity.
Measured: Baseline and weeks 6, 12, 18, 24, 36, 48, 60, and 72
Secondary outcomes (5)
Knee Function (Anterior Knee Pain Scale)
The Anterior Knee Pain Scale assesses symptoms and functional limitations associated with anterior knee pain. The total score ranges from 0 to 100, with higher scores indicating better function and fewer symptoms
Measured: aseline and weeks 6, 12, 18, 24, 36, 48, 60, and 72
Health-Related Quality of Life (EQ-5D)
Health-related quality of life will be assessed using the EuroQol 5-Dimension 5-Level (EQ-5D-5L) questionnaire. Responses will be converted into a utility index using the Belgian value set. Scores range from -0.532 to 1, with higher scores indicating better health-related quality of life.
Measured: Baseline and weeks 6, 12, 18, 24, 36, 48, 60, and 72
Fear of Movement (Tampa Scale for Kinesiophobia)
The 11-item Tampa Scale for Kinesiophobia assesses fear of movement or reinjury. The total score ranges from 11 to 44, with higher scores indicating greater kinesiophobia and therefore a worse outcome
Measured: Baseline and weeks 6, 12, 18, 24, 36, 48, 60, and 72
Pain Catastrophizing (Pain Catastrophizing Scale)
The Pain Catastrophizing Scale is a 13-item questionnaire assessing catastrophic thoughts related to pain. The total score ranges from 0 to 52, with higher scores indicating greater pain catastrophizing and therefore a worse outcome
Measured: Baseline and weeks 6, 12, 18, 24, 36, 48, 60, and 72
Physical Activity (Daily Step Count)
Measured: Daily/weekly
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted25 Sep 2026
- Study startSep 2026 (estimated)
- Primary completionMay 2028 (estimated)
- Study completionDec 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Anterior Knee PainStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 30 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Farraj Miguel
- Sponsor type
- University, hospital or other
- Collaborators
- Brussels Institute for Research and Innovation (INNOVIRIS), moveUP bv
- Responsible party
- Sponsor-investigator, Farraj Miguel, Université Libre de Bruxelles
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07842913
- Sponsor's protocol ID
- AIM2-AKP-001
- Other IDs
- 2024-RDIR-5c
- Status last verified
- Sep 2026
- First submitted
- 21 Sep 2026
- Last updated
- 30 Sep 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 30 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Integrating Hybrid Telerehabilitation Into Routine Physiotherapy Practice for Anterior Knee Pain: Protocol for a Real-World Pragmatic Mixed-Methods Study
- ClinicalTrials.gov ID
- NCT07842913
- Acronym / sponsor ID
- AIM2-AKP-001
- Conditions
- Anterior Knee Pain
- Keywords
- Telerehabilitation, Exercise Adherence, Mobile Health, Physiotherapy
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 30 participants (estimated)
- Lead sponsor
- Farraj MiguelUniversity, hospital or other
- Collaborators
- Brussels Institute for Research and Innovation (INNOVIRIS), moveUP bv
- Study start
- Sep 2026 (estimated)
- Primary completion
- May 2028 (estimated)
- Study completion
- Dec 2028 (estimated)
- First posted
- 25 Sep 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study will examine how hybrid telerehabilitation is used in routine physiotherapy care for adults with anterior knee pain. Approximately 30 participants will be followed for 72 weeks while receiving individualized treatment from their physiotherapist, supported by the moveUP mobile application. The application provides prescribed exercises, educational information, communication with the physiotherapist, and progress monitoring.
The study will assess adherence to rehabilitation, pain, knee function, quality of life, psychological factors, and physical activity. It will also explore whether patient adherence and physiotherapist engagement are associated with clinical outcomes. Interviews with patients and healthcare professionals will examine barriers and facilitators to using the platform in routine care.
Study design
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Hybrid Telerehabilitation | Experimental | Behavioral: Hybrid TelerehabilitationParticipants receive individualized physiotherapy for anterior knee pain supported by the moveUP mobile application over 72 weeks. Treatment is prescribed and adapted by the treating physiotherapist according to individual patient needs. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- Age 18 years or older.
- Clinical diagnosis of anterior knee pain, including patellofemoral pain, patellar tendinopathy, Hoffa's fat pad syndrome, chondromalacia, or femoropatellar, tibiopatellar, or tibiofemoral osteoarthritis not requiring surgery.
- Access to a smartphone compatible with the moveUP application.
Key exclusion criteria (10 listed)
- Currently awaiting spine or lower-limb surgery.
- Lower-limb surgery or other invasive intervention within the previous two years.
- Joint prosthesis.
- Acute trauma to the trunk or lower limbs, or fracture, dislocation, or other musculoskeletal pathology of the affected lower limb within the previous six months.
- Saphenous nerve neuritis or Ehlers-Danlos syndrome.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Hybrid TelerehabilitationHybrid telerehabilitation combining routine physiotherapy with the moveUP mobile application for adults with anterior knee pain. The platform supports individualized exercise prescription, educational modules, patient-physiotherapist communication, and progress monitoring. Exercise selection, frequency, and progression are determined by the treating physiotherapist according to patient needs. Participants are followed for 72 weeks. | Behavioural | Hybrid Telerehabilitation |
Primary outcome
Exercise Adherence (ATEMPT Score)
Time frame: Baseline and weeks 6, 12, 18, 24, 36, 48, 60, and 72
Exercise adherence will be assessed using the Adherence to Exercise for Musculoskeletal Pain Tool (ATEMPT). Total scores range from 6 to 30, with higher scores indicating greater adherence.
Pain Intensity (Visual Analog Scale)
Time frame: Baseline and weeks 6, 12, 18, 24, 36, 48, 60, and 72
Pain intensity will be measured using a 0-100 mm Visual Analog Scale (VAS), where 0 indicates no pain and 100 indicates the worst pain imaginable. Higher scores indicate greater pain intensity.
5 secondary outcomes
Knee Function (Anterior Knee Pain Scale)
Time frame: aseline and weeks 6, 12, 18, 24, 36, 48, 60, and 72
Health-Related Quality of Life (EQ-5D)
Time frame: Baseline and weeks 6, 12, 18, 24, 36, 48, 60, and 72
Fear of Movement (Tampa Scale for Kinesiophobia)
Time frame: Baseline and weeks 6, 12, 18, 24, 36, 48, 60, and 72
Pain Catastrophizing (Pain Catastrophizing Scale)
Time frame: Baseline and weeks 6, 12, 18, 24, 36, 48, 60, and 72
Physical Activity (Daily Step Count)
Time frame: Daily/weekly
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 30 Sep 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
2 sites in 2 countries: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Hybrid Telerehabilitation in people with Anterior Knee Pain, run by Farraj Miguel at 2 sites in 2 countries.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 10 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 30 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 2 sites in Belgium, France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Miguel Farraj, PhD candidate (+32494035113, miguel.farraj@ulb.be), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Exercise Adherence (ATEMPT Score) (time frame: Baseline and weeks 6, 12, 18, 24, 36, 48, 60, and 72). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 30 Sep 2026.