Anterior Knee PainPBMNCT07865325
Photobiomodultion in Anterior Knee Pain
A study testing Photobiomodultion with Laser scanning and patellar mobilization with exercise therapy in people with Anterior Knee Pain and Photobiomodulation (PBM), run by New Ismailia National University at 1 site in Jordan.
Trial summary
The goal of this clinical trial is to assess the augmented recovery in the adolescent females with patellar tendinopathy using Phot- Biomodulation Read more about this study
- Who is it for?
- Ages 14 to 18 years, women onlyHealthy volunteers can take part
- Conditions the study is for
- Anterior Knee Pain, Photobiomodulation (PBM), Laser Therapy
- What is being tested?
- Photobiomodultion with Laser scanning and patellar mobilization with exercise therapy
- Type of treatment
- Medical device
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 104 participants
- Where
- 1 siteJordan
- Study dates
- 16 Jul 2026to Nov 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 14 to 18 years
- Women only
- Healthy volunteers accepted
- Child, Adult
Who may be able to join
- age 14 to 18 years
- young females
- Body Mass Index correlated to age
Who cannot join
- previous surgery
- knee deformities
- autoimmune diseases such as rheumatoid arthritis
- recent healed fracture
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
About this study
Official title: Assessment of Augmented Recovery in the Adolescent Females With Patellar Tendinopathy by Photo- Biomodulation and LASER Scanning Therapy: A Randomized Controlled Trial
The goal of this clinical trial is to assess the augmented recovery in the adolescent females with patellar tendinopathy using Phot- Biomodulation
Read the detailed description
To investigate the effectiveness of photobiomodulation therapy in enhancing recovery among adolescent females diagnosed with patellar tendinopathy.
Primary Objective
To determine the effect of PBM on pain reduction and functional improvement compared with standard rehabilitation alone.
Secondary Objectives To evaluate the effect of PBM on tendon-related disability. To assess changes in knee function and physical performance. To evaluate the impact of PBM on health-related quality of life. To assess the sustainability of treatment effects during follow-up. Study Design
A prospective, randomized, controlled, parallel-group clinical trial.
Participants
Adolescent females aged 12-18 years diagnosed with patellar tendinopathy according to clinical examination and established diagnostic criteria.
Intervention Group
Participants will receive photobiomodulation therapy combined with a standardized exercise-based rehabilitation program.
Control Group
Participants will receive the same standardized rehabilitation program with either sham photobiomodulation or rehabilitation alone.
Outcome Measures
Primary Outcomes
Pain intensity measured using the Visual Analog Scale (VAS) or Numeric Pain Rating Scale (NPRS).
Functional disability measured using the Victorian Institute of Sport Assessment-Patella (VISA-P) questionnaire.
Secondary Outcomes
Knee functional performance tests. Quadriceps muscle strength. Patient-reported functional outcomes. Quality of life assessment.
- Conditions
- Anterior Knee Pain, Photobiomodulation (PBM), Laser Therapy
- Being tested
- Photobiomodultion with Laser scanning, patellar mobilization with exercise therapy
- Keywords
- anterior knee pain, photobiomodulation, laser therapy, young females
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Photobiomodultion with Laser scanningDevice
Also called Exercise therapy
The photobiomodulation intervention consists of applying low-level laser therapy to the anterior knee region using a calibrated laser device with predetermined wavelength, power output, and dosage parameters. The treatment aims to reduce pain, promote tissue healing, and improve functional outcomes. PBM sessions are administered in conjunction with a standardized exercise rehabilitation program throughout the treatment period.
patellar mobilization with exercise therapyOther
Also called therapeutic ultrasound
The intervention consists of therapeutic ultrasound applied to the anterior knee region using standardized treatment parameters, followed by patellar mobilization techniques performed by a trained therapist. The treatment aims to reduce pain, improve patellar mobility, enhance knee function, and facilitate participation in a structured exercise rehabilitation program.
| Study group | Role | What they receive |
|---|---|---|
| Control group | Sham comparator | patients in the control group will receive therapeutic ultrasound, deep friction massage, patellar mobilization, and exercise program Receives: Other: patellar mobilization with exercise therapy |
| interventional group | Experimental | patients in this group will receive photo biomodulation therapy, LASER scanning therapy, and exercise program as given to the control group Receives: Device: Photobiomodultion with Laser scanning |
What is being measured
The primary outcome is the main question the study is designed to answer.
knee pain
Will be measured by pressure algometer which is a handheld instrument used to objectively assess pressure pain threshold (PPT), and defined as the minimum amount of pressure that changes the sensation from pressure alone to the first feeling of pain. A high score means better improvement and vise versa.
Measured: 12 weeks
Secondary outcomes (2)
Range of Motion
Knee joint range of motion will be assessed in degrees using a standard universal goniometer. Measurements of active knee flexion and extension will be recorded to evaluate joint mobility, identify functional limitations, and monitor changes following the intervention period. Increasing the Range of Motion means a better improvement.
Measured: 12 weeks
Patients' Quality of Life
Will be measured by using The Pediatric Quality of Life Inventory scale and considered a standardized, validated questionnaire designed to measure health-related quality of life in children and adolescents aged 2 to 18 years. It evaluates the impact of health conditions on a child's physical, emotional, social, and school functioning. A high score means better improvement and vise versa. Minimum score = 0 and maximum = 100
Measured: 12 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted8 Oct 2026
- Study start16 Jul 2026
- Primary completionOct 2026 (estimated)
- Study completionNov 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Anterior Knee PainStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- the clinical trial will include two groups: control group and interventional group. the control group will receive therapeutic ultrasound, deep friction massage, exercise therapy for enhancing quadriceps/ hamstring ratio ,and patellar mobilization. The treatment group will receive Photobiomodulation, LASER therapy in addition to exercise therapy given to the control group.
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 104 participants (estimated)
Sponsor and investigators
- Lead sponsor
- New Ismailia National University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07865325
- Sponsor's protocol ID
- IRB#15/72025-2026
- Other IDs
- IRB#15/72025-2026
- Acronym
- PBM
- Status last verified
- Oct 2026
- First submitted
- 22 Sep 2026
- Last updated
- 8 Oct 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 8 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Assessment of Augmented Recovery in the Adolescent Females With Patellar Tendinopathy by Photo- Biomodulation and LASER Scanning Therapy: A Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT07865325
- Acronym / sponsor ID
- PBM / IRB#15/72025-2026
- Conditions
- Anterior Knee Pain, Photobiomodulation (PBM), Laser Therapy
- Keywords
- anterior knee pain, photobiomodulation, laser therapy, young females
- Study type
- Interventional
- Recruitment status
- Enrolling by invitation
- Enrolment
- 104 participants (estimated)
- Lead sponsor
- New Ismailia National UniversityUniversity, hospital or other
- Study start
- 16 Jul 2026 (actual)
- Primary completion
- Oct 2026 (estimated)
- Study completion
- Nov 2026 (estimated)
- First posted
- 8 Oct 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this clinical trial is to assess the augmented recovery in the adolescent females with patellar tendinopathy using Phot- Biomodulation
Detailed description
To investigate the effectiveness of photobiomodulation therapy in enhancing recovery among adolescent females diagnosed with patellar tendinopathy.
Primary Objective
To determine the effect of PBM on pain reduction and functional improvement compared with standard rehabilitation alone.
Secondary Objectives To evaluate the effect of PBM on tendon-related disability. To assess changes in knee function and physical performance. To evaluate the impact of PBM on health-related quality of life. To assess the sustainability of treatment effects during follow-up. Study Design
A prospective, randomized, controlled, parallel-group clinical trial.
Participants
Adolescent females aged 12-18 years diagnosed with patellar tendinopathy according to clinical examination and established diagnostic criteria.
Intervention Group
Participants will receive photobiomodulation therapy combined with a standardized exercise-based rehabilitation program.
Control Group
Participants will receive the same standardized rehabilitation program with either sham photobiomodulation or rehabilitation alone.
Outcome Measures
Primary Outcomes
Pain intensity measured using the Visual Analog Scale (VAS) or Numeric Pain Rating Scale (NPRS).
Functional disability measured using the Victorian Institute of Sport Assessment-Patella (VISA-P) questionnaire.
Secondary Outcomes
Knee functional performance tests. Quadriceps muscle strength. Patient-reported functional outcomes. Quality of life assessment.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
- Model description
- the clinical trial will include two groups: control group and interventional group. the control group will receive therapeutic ultrasound, deep friction massage, exercise therapy for enhancing quadriceps/ hamstring ratio ,and patellar mobilization. The treatment group will receive Photobiomodulation, LASER therapy in addition to exercise therapy given to the control group.
| Arm | Type | Receives |
|---|---|---|
| Control group | Sham comparator | Other: patellar mobilization with exercise therapypatients in the control group will receive therapeutic ultrasound, deep friction massage, patellar mobilization, and exercise program |
| interventional group | Experimental | Device: Photobiomodultion with Laser scanningpatients in this group will receive photo biomodulation therapy, LASER scanning therapy, and exercise program as given to the control group |
Who may qualify
- Ages
- 14 to 18 years
- Sex
- Female only
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult
Key inclusion criteria (3 listed)
- age 14 to 18 years
- young females
- Body Mass Index correlated to age
Key exclusion criteria (4 listed)
- previous surgery
- knee deformities
- autoimmune diseases such as rheumatoid arthritis
- recent healed fracture
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Photobiomodultion with Laser scanningAlso: Exercise therapyThe photobiomodulation intervention consists of applying low-level laser therapy to the anterior knee region using a calibrated laser device with predetermined wavelength, power output, and dosage parameters. The treatment aims to reduce pain, promote tissue healing, and improve functional outcomes. PBM sessions are administered in conjunction with a standardized exercise rehabilitation program throughout the treatment period. | Device | interventional group |
| patellar mobilization with exercise therapyAlso: therapeutic ultrasoundThe intervention consists of therapeutic ultrasound applied to the anterior knee region using standardized treatment parameters, followed by patellar mobilization techniques performed by a trained therapist. The treatment aims to reduce pain, improve patellar mobility, enhance knee function, and facilitate participation in a structured exercise rehabilitation program. | Other | Control group |
Primary outcome
knee pain
Time frame: 12 weeks
Will be measured by pressure algometer which is a handheld instrument used to objectively assess pressure pain threshold (PPT), and defined as the minimum amount of pressure that changes the sensation from pressure alone to the first feeling of pain. A high score means better improvement and vise versa.
2 secondary outcomes
Range of Motion
Time frame: 12 weeks
Patients' Quality of Life
Time frame: 12 weeks
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 8 Oct 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Photobiomodultion with Laser scanning and patellar mobilization with exercise therapy in people with Anterior Knee Pain and Photobiomodulation (PBM), run by New Ismailia National University at 1 site in Jordan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: enrolling by invitation, as of the sponsor's last update on 8 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Jordan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
knee pain (time frame: 12 weeks). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 8 Oct 2026.