Horizontal Alveolar Bone LossNCT07848711
Comparison of Two Expansion Techniques for Horizontal Bone Deficiency
A study testing Bone expansion and implant placement with crest split and Bone expansion and implant placement with specifically design drills in people with Horizontal Alveolar Bone Loss and Implant Therapy, run by Ege University at 1 site in Turkey (Türkiye).
Trial summary
This was a prospective, randomized clinical trial conducted at the Department of Oral and Maxillofacial Surgery, Ege University. Patients exhibiting horizontal bone insufficiency (residual crest width < 4 mm) in the posterior mandible received dental implants with two techniques: osseodensification or crest split. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Horizontal Alveolar Bone Loss, Implant Therapy, Primary Stability of the Implants
- What is being tested?
- Bone expansion and implant placement with crest split and Bone expansion and implant placement with specifically design drills
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 20 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 1 Dec 2023to 2 Sep 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- a residual horizontal alveolar crest width of less than 4 mm
- clinical indication for at least two implants
- good systemic health
Who cannot join
- patients requiring vertical augmentation
- tooth extraction prior or peri-surgery
- presence of acute local infection or pathology at the operative site
- allergy to titanium, anesthetics, or surgical materials
- pregnancy or lactation
- history of bisphosphonate or antiresorptive use
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Clinical and Radiological Comparison of Two Different Expansion Techniques in Patients With Horizontal Bone Sufficiency
This was a prospective, randomized clinical trial conducted at the Department of Oral and Maxillofacial Surgery, Ege University. Patients exhibiting horizontal bone insufficiency (residual crest width < 4 mm) in the posterior mandible received dental implants with two techniques: osseodensification or crest split. The investigator compared to clinical and radiological outcomes of these techniques.
Read the detailed description
This prospective, parallel-group randomized clinical trial was conducted at the Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Ege University, İzmir, Turkey, between February 2021 and August 2023.Patients exhibiting horizontal bone insufficiency (residual crest width < 4 mm) in the posterior mandible received dental implants with two techniques. The primary predictor variable was the ridge expansion technique: Osseodensification (Group 1, n=10 patients, 21 implants) or Crest Split (Group 2, n=10 patients, 25 implants). primary outcome variables were primary stability. The secondary outcome variables were clinical bone expansion, intraoperative/postoperative complications, marginal bone level, plaque accumulation, and bleeding on probing.
- Conditions
- Horizontal Alveolar Bone Loss, Implant Therapy, Primary Stability of the Implants, Complication, Periodontal Health
- Being tested
- Bone expansion and implant placement with crest split, Bone expansion and implant placement with specifically design drills
- Keywords
- alveolar ridge deficiency, crest split, expansion, implant, complication, radiological assessment, marginal bone level
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Bone expansion and implant placement with crest splitProcedure or surgery
Bone expansion was provided with chisel and mullet. Implant was inserted following expansion.
Bone expansion and implant placement with specifically design drillsProcedure or surgery
Bone expansion was provided with implant drills. Implant was inserted following expansion.
| Study group | Role | What they receive |
|---|---|---|
| Crest Split | Active comparator | Bone expansion and implant placement with crest split Receives: Procedure: Bone expansion and implant placement with crest split |
| Drill system | Experimental | Bone expansion and implant placement with specifically design drills Receives: Procedure: Bone expansion and implant placement with specifically design drills |
What is being measured
The primary outcome is the main question the study is designed to answer.
Mean of implant stability quantity (ISQ) value
Calculation of ISQ value: Measurement for each implant using resonance frequency analysis (RFA)
Measured: At surgery
Mean of torque value
Calculation of torque value: Measurement for each implant using a ratchet and torque wrench
Measured: At surgery
Secondary outcomes (3)
Marginal bone level
Change in peri-implant bone level
Measured: through study completion, ana average of 2 year
Complication
Number of operative and postoperative complications
Measured: through study completion, an average of 2 year
Peri-implant health
Calculation of bleeding on probing and plaque accumulation. Bleeding on probing: Assessment of bleeding presence/absence using a periodontal probe.
Plaque accumulation: Assessment of plaque presence/absence using a modified plaque index.
Measured: at 12 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted30 Sep 2026
- Study start1 Dec 2023
- Primary completion1 Jun 2024
- Study completion2 Sep 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Horizontal Alveolar Bone LossStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Investigator
- Enrolment
- 20 participants (actual)
Sponsor and investigators
- Lead sponsor
- Ege University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Gözde Işık, Ege University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07848711
- Sponsor's protocol ID
- 23-5/64
- Other IDs
- 2022-032
- Status last verified
- Dec 2023
- First submitted
- 24 Sep 2026
- Last updated
- 2 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 2 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Clinical and Radiological Comparison of Two Different Expansion Techniques in Patients With Horizontal Bone Sufficiency
- ClinicalTrials.gov ID
- NCT07848711
- Acronym / sponsor ID
- 23-5/64
- Conditions
- Horizontal Alveolar Bone Loss, Implant Therapy, Primary Stability of the Implants, Complication, Periodontal Health
- Keywords
- alveolar ridge deficiency, crest split, expansion, implant, complication, radiological assessment, marginal bone level
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 20 participants (actual)
- Lead sponsor
- Ege UniversityUniversity, hospital or other
- Study start
- 1 Dec 2023 (actual)
- Primary completion
- 1 Jun 2024 (actual)
- Study completion
- 2 Sep 2024 (actual)
- First posted
- 30 Sep 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This was a prospective, randomized clinical trial conducted at the Department of Oral and Maxillofacial Surgery, Ege University. Patients exhibiting horizontal bone insufficiency (residual crest width < 4 mm) in the posterior mandible received dental implants with two techniques: osseodensification or crest split. The investigator compared to clinical and radiological outcomes of these techniques.
Detailed description
This prospective, parallel-group randomized clinical trial was conducted at the Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Ege University, İzmir, Turkey, between February 2021 and August 2023.Patients exhibiting horizontal bone insufficiency (residual crest width < 4 mm) in the posterior mandible received dental implants with two techniques. The primary predictor variable was the ridge expansion technique: Osseodensification (Group 1, n=10 patients, 21 implants) or Crest Split (Group 2, n=10 patients, 25 implants). primary outcome variables were primary stability. The secondary outcome variables were clinical bone expansion, intraoperative/postoperative complications, marginal bone level, plaque accumulation, and bleeding on probing.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (investigator)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Crest Split | Active comparator | Procedure: Bone expansion and implant placement with crest splitBone expansion and implant placement with crest split |
| Drill system | Experimental | Procedure: Bone expansion and implant placement with specifically design drillsBone expansion and implant placement with specifically design drills |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- a residual horizontal alveolar crest width of less than 4 mm
- clinical indication for at least two implants
- good systemic health
Key exclusion criteria (6 listed)
- patients requiring vertical augmentation
- tooth extraction prior or peri-surgery
- presence of acute local infection or pathology at the operative site
- allergy to titanium, anesthetics, or surgical materials
- pregnancy or lactation
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Bone expansion and implant placement with crest splitBone expansion was provided with chisel and mullet. Implant was inserted following expansion. | Procedure or surgery | Crest Split |
| Bone expansion and implant placement with specifically design drillsBone expansion was provided with implant drills. Implant was inserted following expansion. | Procedure or surgery | Drill system |
Primary outcome
Mean of implant stability quantity (ISQ) value
Time frame: At surgery
Calculation of ISQ value: Measurement for each implant using resonance frequency analysis (RFA)
Mean of torque value
Time frame: At surgery
Calculation of torque value: Measurement for each implant using a ratchet and torque wrench
3 secondary outcomes
Marginal bone level
Time frame: through study completion, ana average of 2 year
Complication
Time frame: through study completion, an average of 2 year
Peri-implant health
Time frame: at 12 months
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 2 Oct 2026.
- Individual participant dataSharing planned: No
Related trials for Horizontal Alveolar Bone Loss
Enrolling by invitation
Investigation of the Effect of Horizontal Platelet Rich Fibrin Placed in Tooth Extraction Sockets on Bone Formation
Tooth Loss, Dental Implant Failed
Not yet recruiting
Autogenous and Xenograft Bone Mix in Alveolar Ridge Reconstruction
Horizontal Alveolar Ridge Deficiency
Not yet recruiting
Comparison of Three Autogenous Bone and Xenograft Ratios for Horizontal Ridge Augmentation
Horizontal Alveolar Ridge Deficiency
Not yet recruiting
Comparison of Two Autogenous Bone and Xenograft Ratios for Horizontal Ridge Augmentation
Horizontal Alveolar Ridge Deficiency
Recruiting
Histological and Histomorphometric Assessment With Inflammatory Profile Analysis of Bone Tissue After Horizontal Ridge Augmentation Using Customized Porous Zirconia Shell
Alveolar Bone Loss, Alveolar Ridge Deficiency
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Bone expansion and implant placement with crest split and Bone expansion and implant placement with specifically design drills in people with Horizontal Alveolar Bone Loss and Implant Therapy, run by Ege University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 2 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Mean of implant stability quantity (ISQ) value (time frame: At surgery). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 2 Oct 2026.