Clinical trials: Periodontal Health
Gingivitis
Powered Toothbrush Versus Manual Toothbrush on Plaque and Gingivitis After a Six-Week Period of Home Use
The goal of this clinical trial is to learn if powered toothbrushing is more effective than manual toothbrushing in removing dental plaque. It will also learn about the safety of power toothbrushing.
- Trial name
- NCT07691814
- Testing
- power toothbrush, manual toothbrush
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Philips Clinical & Medical Affairs Global
Peri-Implant Health, Peri Implant Mucositis
Impact of Smoking on Immune Responses in Peri-implant Health and Disease
Peri-implant diseases are inflammatory conditions affecting the gums and bone around dental implants. Peri-implant mucositis causes inflammation in the gums, while peri-implantitis can also lead to bone loss and, in severe cases…
- Conditions
- Peri-Implant Health, Peri Implant Mucositis, Peri-implantitis
- Trial name
- NCT07750171
- Where
- Turkey (Türkiye)
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Gazi University
Periodontal Diseases, Dental Plaque
Oral Health Literacy Tailored Communication
The purpose of this study to investigate attitude, oral health literacy and psychological factors in order to evaluate if these factors are important for oral health in adults.
- Conditions
- Periodontal Diseases, Dental Plaque, Dental Calculus, Sialorrhea
- Trial name
- NCT01118143
- Testing
- Tailored oral health literacy instruction
- Where
- 2 sites in Norway
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- University of Tromso
Gingivitis
Miswak Efficacy Compared With Chlorhexidine
Gingivitis is a form of gum disease and is elicited by the accumulation of plaque on the tooth and the soft-tissue adjoining the tooth.
- Trial name
- MiswakChlorx (NCT04607785)
- Testing
- Miswak mouthwash group, Chlorhexidine gluconate mouthwash
- Where
- Iraq
- Volunteers
- 60 people
- Sponsor
- Al-Iraqia University
Gingival Inflammation, Dental Caries
Effectiveness of Toothpaste Tablets on Plaque, Gingival Health and Caries Experiences
Objectives: To evaluate the effectiveness of toothpaste tablets when compared to conventional dentifrices in removing plaque. Methods: 50 participants are randomized into two groups: Denttabs toothpaste tablets (T) and Colgate's…
- Trial name
- NCT07124533
- Testing
- Toothpaste Tablet, Conventional Toothpaste
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Chronic Periodontitis
Efficacy of a Probiotic Lozenge (Inersan) in Patients With Chronic Periodontitis
Periodontal disease is a major cause of tooth loss in humans and is one of the most prevalent diseases associated with bone loss.
- Trial name
- NCT01870362
- Testing
- Probiotic (Inersan)
- Where
- India
- Volunteers
- 28 people
- Sponsor
- CD Pharma India Pvt. Ltd.
Gingivitis
The Effect of Probiotics on Gums Health and Bad Breath
the study is about using healthy bacteria to improve the overall gingival and overall health and prevent or decrease the bad odor of the mouth caused by bad bacteria
- Trial name
- NCT06910397
- Testing
- Probiotic Arm
- Where
- Iraq
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University
Periodontal Disease, Non-diseased Patients
The Importance of Periostin in Periodontal Health and Disease
The goal of this study is to determine the clinical importance of Periostin in oral health and disease. The long-term goal will be to develop practical applications for the diagnosis, treatment, prevention and cure of human…
- Trial name
- NCT01180920
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Diabetes Mellitus Type 2 With Periodontal Disease
Using AR Dental Care Training System in HE on Periodontal Status, Blood Sugar Control and QoL in Patients With T2DM
The aim of this study was to evaluate the long-term effectiveness of an AR dental care training in health education on periodontal status, blood sugar control and quality of life in patients with poorly controlled type 2…
- Trial name
- NCT05941468
- Testing
- AR Dental Care Training System
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Dental Plaque, Gingivitis
A Clinical Study to Evaluate the Efficacy of a Cetylpyridinium Chloride Mouthwash in Improving Gingival Health and Reducing Plaque Accumulation
The aim of this 12-week clinical study is to evaluate the ability of an experimental mouthwash, containing 0.085 percent (%) Cetylpyridinium chloride (CPC) as an adjunct to toothbrushing with a regular fluoride toothpaste, to…
- Trial name
- NCT06933368
- Testing
- Crest Cavity Protection Toothpaste, Experimental Mouthwash
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- HALEON
Epilepsy, Gingivitis
Air Polishing Effect on Biological, Clinical and Patient-reported Experience Among Epileptic and Non-epileptic Children
In epileptic and non Epileptic children, the full dentition of each patient was split into four quadrants, starting from the upper right quadrant (1) and moving clockwise until the lower right quadrant (4).
- Trial name
- NCT06144034
- Testing
- Air polishing with erythritol powder, Conventional treatment
- Where
- 2 sites in Jordan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Peri-implantitis
Investigation of Macrophage Polarization in Peri-implant Health and Peri-implantitis
Peri-implantitis is a chronic inflammatory disease characterized by plaque-associated inflammation of the peri-implant mucosa and progressive loss of supporting bone around dental implants, which may ultimately lead to implant…
- Trial name
- NCT07569432
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Biruni University
Dental Caries, Dry Mouth
Oral Health Intervention in Adult Primary Care
This study is a Stage III cRCT to test the efficacy of multi-level interventions at the practice- and provider-level to address low dental utilization (attendance) among Medicaid-enrolled older adults 55 years or older attending…
- Conditions
- Dental Caries, Dry Mouth, Periodontal Diseases, Bleeding Gum
- Trial name
- NCT06555029
- Testing
- EHR Changes, Medical Staff EHR Training, Clinician CSM theory-based didactic education and skills training, Standard ADA Oral Health Training
- Where
- United States
- Volunteers
- 929 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Mental Health Issue, Periodontitis
Association Between Periodontal Status and Mental Health in Postpartum Women
Background- In developing countries like India, seeking mental health care is still a taboo, and a lot of stigma is attached to consulting a psychiatric specialist or a counselor.
- Conditions
- Mental Health Issue, Periodontitis, Periodontal Diseases
- Trial name
- NCT05869981
- Where
- India
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Gingivitis
A Clinical Study to Evaluate the Efficacy of a Range of Dental/Denture Products for Improved Oral Health in Partial Denture Wearers
The purpose of this study is to investigate the effectiveness of usage of a range of oral products (toothpaste, mouth rinse, denture cleanser) on the oral health of partial denture wearers compared to existing oral hygiene…
- Trial name
- NCT04290624
- Testing
- Experimental Dentifrice: Stannous Fluoride, COREGA Denture Foaming Cleanser, Mouth rinse: Sodium Fluoride
- Where
- United Kingdom
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- HALEON
Gingivitis, Oral Disease
Metagenome Resilience in Experimental Gingivitis
This study aims to identify new biomarkers that indicate the resilience of individuals to developing oral disease. An 'experimental gingivitis' model will be employed in which subjects will refrain from oral hygiene in one…
- Trial name
- NCT05389124
- Testing
- Partial abstinence from oral hygiene
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Newcastle University
Chronic Periodontitis
Effect of Pranayama on Periodontal Health
The objective of the study was to evaluate the levels of Peroxisome proliferator-activated receptor gamma (PPAR-γ), Nuclear factor-kappa B (NF-kB) and the presence of red complex microorganisms (RCM) such as Treponema denticola…
- Trial name
- NCT02967861
- Testing
- Pranayama, Scaling and root planing
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Meenakshi Ammal Dental College and Hospital
Obesity, Periodontitis
Evaluation of the Dental Health Condition in Obesity Patients Before and After Bariatric Surgery
The aim of this study is to investigate whether there was an association between obesity and periodontitis, tendency to caries and periapical lesions.
- Conditions
- Obesity, Periodontitis, Caries, Periapical Lesion
- Trial name
- NCT00531154
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Periodontitis, Gingivitis
Relationship Between Periodontal Inflammation Severity and Pan-Immune System Inflammation Value
This cross-sectional observational study aims to evaluate the relationship between periodontal inflammation severity and the Pan-Immune-Inflammation Value (PIV) in systemically healthy adults.
- Conditions
- Periodontitis, Gingivitis, Periodontal Health
- Trial name
- NCT07628803
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Chronic Periodontitis, Diabetes Mellitus, Type 2
Effectiveness of Non-surgical Periodontal Treatment on HbA1c Levels in a Patient With Type 2 Diabetes Mellitus
This study evaluates the effectiveness of an intervention, non-surgical periodontal treatment (SPR), in patients with poorly controlled type 2 diabetes mellitus and moderate-severe periodontal disease aimed at reducing HbA1c…
- Trial name
- NCT04051866
- Testing
- Non-surgical periodontal treatment: Scaling and root planing (SRP), Oral hygiene instructions
- Where
- Spain
- Sponsor
- Gerencia de Atención Primaria, Madrid