Healthy AdultNCT07854938
Interaction Between White Potato Consumption and Meal Timing on Glycemic Response and Appetite in Adults [Experiment 2]
A study testing Oven-baked Home Fries, Oven-baked White Russet Potato and Oven-baked Fries in people with Healthy Adult and Appetite, run by Toronto Metropolitan University at 1 site in Canada.
Trial summary
The purpose of this study is to evaluate the interaction between white potato consumption and meal timing on glycemic response, subjective appetite, and energy intake in adults. The investigators hypothesize that white potatoes will modulate glycemic response, enhance satiety, and mitigate subsequent meal consumption… Read more about this study
- Who is it for?
- Ages 18 to 65 yearsHealthy volunteers can take part
- Conditions the study is for
- Healthy Adult, Appetite, Mealtiming
- What is being tested?
- Oven-baked Home Fries, Oven-baked White Russet Potato and Oven-baked Fries
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 30 participants
- Where
- 1 siteCanada
- Study dates
- Sep 2026to Oct 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- 18 - 65 years
- within the healthy body weight range [body mass index (BMI) between 18.5 - 24.9 kg/m2].
Who cannot join
- have a previous diagnosis of diabetes and gastrointestinal, liver or kidney disease;
- have had a major medical or surgical event within the past 6 months;
- have had any significant weight fluctuation in the past 6-months;
- are taking medication that may influence dependent measures;
- are or have been on a diet within the past 6 months;
- skip breakfast or are unable to consume test treatment food.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Canada1 site, 1 recruiting
- Recruiting
Centre for Urban Centre for Urban Innovation (CUI-109), School of Nutrition, Toronto Metropolitan University
Toronto, Ontario, M5B 2K3
Nick Bellissimo, PhD, 1 + 416-979-5000 ext. 553103, nick.bellissimo@torontomu.ca
About this study
The purpose of this study is to evaluate the interaction between white potato consumption and meal timing on glycemic response, subjective appetite, and energy intake in adults. The investigators hypothesize that white potatoes will modulate glycemic response, enhance satiety, and mitigate subsequent meal consumption and overall food intake when compared with meals containing low glycemic carbohydrates. Furthermore, they anticipate that the timing of white potato consumption will yield differential effects, with breakfast consumption exerting a more pronounced impact on satiety and subsequent food intake reduction compared to dinner consumption.
Read the detailed description
A randomized within-subject repeated measures experiment will be used to study the interaction between white potato consumption and meal timing on glycemic response, subjective appetite, and energy intake in adults. In Experiment 2, participants will consume, in a random order on separate evenings, one of six test meals consisting of an meatballs and gravy and a test side of: (1) Oven-baked home fries, (2) Oven-baked white russet potatoes, (3) Deep-fried, quick serve fries, (4) Oven-baked fries, (5) Oven-baked cauliflower tots, or (6) no side. Acute glycemic response and subjective appetite will be measured at baseline and over 120-mins post treatment consumption. Rest of day food intake and glycemic response will be collected for 24 hours post session. Blood glucose measurements will be collected using the Dexcom G7 continuous glucose monitoring system. Upon awakening in the morning [day after evening session], participants will consume a standardized breakfast ad libitum. Sleep will be evaluated via a VAS questionnaire and subjective appetite will be evaluated for 120-min post breakfast consumption. Dietary intake for the entire day [post-breakfast consumption; day after evening session] will be collected via a food record.
- Conditions
- Healthy Adult, Appetite, Mealtiming, Glycemic Response
- Being tested
- Oven-baked Home Fries, Oven-baked White Russet Potato, Oven-baked Fries, Deep Fried, Quick Serve Fries, Oven-baked Cauliflower Veggie Tots
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Oven-baked Home FriesOther
Oven-baked Home Fries (241 g; McCain Ltd.). Test treatments matched for calories (284 kcal)
Oven-baked White Russet PotatoOther
Oven-baked White Russet Potato (299 g). Test treatments matched for calories (284 kcal)
Oven-baked FriesOther
Oven-baked Fries (241 g; McCain Ltd.). Test treatments matched for calories (284 kcal)
Deep Fried, Quick Serve FriesOther
Deep Fried, Quick Serve Fries (108 g; McCain Ltd.). Test treatments matched for calories (284 kcal)
Oven-baked Cauliflower Veggie TotsOther
Oven-baked Cauliflower Veggie Tots (172 g; Green Giant). Test treatments matched for calories (284 kcal)
No SideOther
No side control (no caloric contribution).
| Study group | Role | What they receive |
|---|---|---|
| Oven-baked Home Fries | Experimental | Test Treatment Receives: Other: Oven-baked Home Fries |
| Oven-baked White Russet Potato | Experimental | Test Treatment Receives: Other: Oven-baked White Russet Potato |
| Oven-baked Fries | Experimental | Test Treatment Receives: Other: Oven-baked Fries |
| Deep Fried, Quick Serve Fries | Experimental | Test Treatment Receives: Other: Deep Fried, Quick Serve Fries |
| Oven-baked Cauliflower Veggie Tots | Experimental | Test Treatment Receives: Other: Oven-baked Cauliflower Veggie Tots |
| No Side | Experimental | Test Treatment Receives: Other: No Side |
What is being measured
The primary outcome is the main question the study is designed to answer.
Glycemic Response (Acute Phase)
Blood glucose (mmol/L). Blood glucose concentrations will be measured using a Dexcom G7 CGM system.
Measured: Change from baseline (measured at baseline (0-minute), 15-minute, 30-minute, 60-minute, 90-minute, and 120-minute post-treatment consumption).
Subjective Appetite
A visual analogue scale (VAS) with four questions will be administered to assess desire to eat, fullness, hunger, and prospective food consumption. Individual questions will be used to form a composite score. Each VAS will be administered via pen and paper where participants will place an 'X" on the VAS line (100 mm).
Measured: Change from baseline (measured at baseline (0-minute), 15-minute, 30-minute, 60-minute, 90-minute, and 120-minute post-treatment consumption).
Rest-of-day Blood Glucose
Blood glucose (mmol/L). Rest-of-day blood glucose concentrations will be determined using a Dexcom G7 CGM system.
Measured: Continuous measurements for 24 hours post-treatment consumption.
Secondary outcomes (5)
Subjective Emotions
A visual analogue scale (VAS) with thirteen questions will be administered to assess subjective emotions and mood (aggression, anger, excitement, disappointment, happiness, upset, frustration, alertness, sadness, tension, exhaustion, calmness, and sleepiness). Individual questions will be used to form a composite emotion score. Each VAS will be administered via pen and paper where participants will place an 'X" on the VAS line (100 mm).
Measured: Change from baseline (measured at baseline (0-minute), 15-minute, 30-minute, 60-minute, 90-minute, and 120-minute post-treatment consumption).
Sleep Quality
A visual analogue scale (VAS) with five questions will be provided to participants to answer upon waking the day after the test session [i.e. morning after evening test session]. Each VAS will be administered via pen and paper where participants will place an 'X" on the VAS line (100 mm).
Measured: Measured at baseline (0-min); upon awakening
Rest-of-day and next day Food Intake
Participants will be sent home with a rest-of-the-day and next-day food intake recall sheet to record their snacks, meals, and beverages.
Measured: For the rest of the day following test session completion and next day (1 day)
Next-day Subjective Appetite
A visual analogue scale (VAS) with four questions will be provided to assess desire to eat, fullness, hunger, and prospective food consumption. Individual questions will be used to form a composite score. Each VAS will be administered via pen and paper, provided to participants to complete at home the morning after the evening test session.
Measured: Change from baseline (measured at baseline (0-minute), 30-minute, 60-minute, and 120-minute post-breakfast consumption).
Food Intake
Ad libitum food intake will be determined from a standardized breakfast consumed the morning after the evening test session. Food intake will be collected via food record and photo food log.
Measured: Morning-after evening test session (upon waking). Measured at baseline (0-min); upon awakening.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted2 Oct 2026
- Study startSep 2026 (estimated)
- Primary completionOct 2027 (estimated)
- Study completionOct 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Healthy AdultStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- None (open label)
- Enrolment
- 30 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Toronto Metropolitan University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Nick Bellissimo, PhD, Toronto Metropolitan University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07854938
- Sponsor's protocol ID
- REB: 25 - 172 [B]
- Status last verified
- Sep 2026
- First submitted
- 22 Sep 2026
- Last updated
- 2 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 2 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Interaction Between White Potato Consumption and Meal Timing on Glycemic Response and Appetite in Adults [Experiment 2]
- ClinicalTrials.gov ID
- NCT07854938
- Acronym / sponsor ID
- REB: 25 - 172 [B]
- Conditions
- Healthy Adult, Appetite, Mealtiming, Glycemic Response
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 30 participants (estimated)
- Lead sponsor
- Toronto Metropolitan UniversityUniversity, hospital or other
- Study start
- Sep 2026 (estimated)
- Primary completion
- Oct 2027 (estimated)
- Study completion
- Oct 2027 (estimated)
- First posted
- 2 Oct 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of this study is to evaluate the interaction between white potato consumption and meal timing on glycemic response, subjective appetite, and energy intake in adults. The investigators hypothesize that white potatoes will modulate glycemic response, enhance satiety, and mitigate subsequent meal consumption and overall food intake when compared with meals containing low glycemic carbohydrates. Furthermore, they anticipate that the timing of white potato consumption will yield differential effects, with breakfast consumption exerting a more pronounced impact on satiety and subsequent food intake reduction compared to dinner consumption.
Detailed description
A randomized within-subject repeated measures experiment will be used to study the interaction between white potato consumption and meal timing on glycemic response, subjective appetite, and energy intake in adults. In Experiment 2, participants will consume, in a random order on separate evenings, one of six test meals consisting of an meatballs and gravy and a test side of: (1) Oven-baked home fries, (2) Oven-baked white russet potatoes, (3) Deep-fried, quick serve fries, (4) Oven-baked fries, (5) Oven-baked cauliflower tots, or (6) no side. Acute glycemic response and subjective appetite will be measured at baseline and over 120-mins post treatment consumption. Rest of day food intake and glycemic response will be collected for 24 hours post session. Blood glucose measurements will be collected using the Dexcom G7 continuous glucose monitoring system. Upon awakening in the morning [day after evening session], participants will consume a standardized breakfast ad libitum. Sleep will be evaluated via a VAS questionnaire and subjective appetite will be evaluated for 120-min post breakfast consumption. Dietary intake for the entire day [post-breakfast consumption; day after evening session] will be collected via a food record.
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- None (open label)
- Number of arms
- 6
| Arm | Type | Receives |
|---|---|---|
| Oven-baked Home Fries | Experimental | Other: Oven-baked Home FriesTest Treatment |
| Oven-baked White Russet Potato | Experimental | Other: Oven-baked White Russet PotatoTest Treatment |
| Oven-baked Fries | Experimental | Other: Oven-baked FriesTest Treatment |
| Deep Fried, Quick Serve Fries | Experimental | Other: Deep Fried, Quick Serve FriesTest Treatment |
| Oven-baked Cauliflower Veggie Tots | Experimental | Other: Oven-baked Cauliflower Veggie TotsTest Treatment |
| No Side | Experimental | Other: No SideTest Treatment |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (2 listed)
- 18 - 65 years
- within the healthy body weight range [body mass index (BMI) between 18.5 - 24.9 kg/m2].
Key exclusion criteria (6 listed)
- have a previous diagnosis of diabetes and gastrointestinal, liver or kidney disease;
- have had a major medical or surgical event within the past 6 months;
- have had any significant weight fluctuation in the past 6-months;
- are taking medication that may influence dependent measures;
- are or have been on a diet within the past 6 months;
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Oven-baked Home FriesOven-baked Home Fries (241 g; McCain Ltd.). Test treatments matched for calories (284 kcal) | Other | Oven-baked Home Fries |
| Oven-baked White Russet PotatoOven-baked White Russet Potato (299 g). Test treatments matched for calories (284 kcal) | Other | Oven-baked White Russet Potato |
| Oven-baked FriesOven-baked Fries (241 g; McCain Ltd.). Test treatments matched for calories (284 kcal) | Other | Oven-baked Fries |
| Deep Fried, Quick Serve FriesDeep Fried, Quick Serve Fries (108 g; McCain Ltd.). Test treatments matched for calories (284 kcal) | Other | Deep Fried, Quick Serve Fries |
| Oven-baked Cauliflower Veggie TotsOven-baked Cauliflower Veggie Tots (172 g; Green Giant). Test treatments matched for calories (284 kcal) | Other | Oven-baked Cauliflower Veggie Tots |
| No SideNo side control (no caloric contribution). | Other | No Side |
Primary outcome
Glycemic Response (Acute Phase)
Time frame: Change from baseline (measured at baseline (0-minute), 15-minute, 30-minute, 60-minute, 90-minute, and 120-minute post-treatment consumption).
Blood glucose (mmol/L). Blood glucose concentrations will be measured using a Dexcom G7 CGM system.
Subjective Appetite
Time frame: Change from baseline (measured at baseline (0-minute), 15-minute, 30-minute, 60-minute, 90-minute, and 120-minute post-treatment consumption).
A visual analogue scale (VAS) with four questions will be administered to assess desire to eat, fullness, hunger, and prospective food consumption. Individual questions will be used to form a composite score. Each VAS will be administered via pen and paper where participants will place an 'X" on the VAS line (100 mm).
Rest-of-day Blood Glucose
Time frame: Continuous measurements for 24 hours post-treatment consumption.
Blood glucose (mmol/L). Rest-of-day blood glucose concentrations will be determined using a Dexcom G7 CGM system.
5 secondary outcomes
Subjective Emotions
Time frame: Change from baseline (measured at baseline (0-minute), 15-minute, 30-minute, 60-minute, 90-minute, and 120-minute post-treatment consumption).
Sleep Quality
Time frame: Measured at baseline (0-min); upon awakening
Rest-of-day and next day Food Intake
Time frame: For the rest of the day following test session completion and next day (1 day)
Next-day Subjective Appetite
Time frame: Change from baseline (measured at baseline (0-minute), 30-minute, 60-minute, and 120-minute post-breakfast consumption).
Food Intake
Time frame: Morning-after evening test session (upon waking). Measured at baseline (0-min); upon awakening.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 2 Oct 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Oven-baked Home Fries, Oven-baked White Russet Potato and Oven-baked Fries in people with Healthy Adult and Appetite, run by Toronto Metropolitan University at 1 site in Canada.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 2 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Canada. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Nick Bellissimo, PhD (1 + 4169795000 ext. 553103, nick.bellissimo@torontomu.ca), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Glycemic Response (Acute Phase) (time frame: Change from baseline (measured at baseline (0-minute), 15-minute, 30-minute, 60-minute, 90-minute, and 120-minute post-treatment consumption).). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 2 Oct 2026.