Postprandial Glycemic ResponseNCT07855744
Effects of Chocolates With Different Cocoa Content on Postprandial Blood Glucose in Healthy Adults
A study testing 55% Cocoa Chocolate, 60% Cocoa Chocolate and 72% Cocoa Chocolate in people with Postprandial Glycemic Response, run by Bandırma Onyedi Eylül University at 1 site in Turkey (Türkiye).
Trial summary
This randomized controlled study evaluated how chocolates with different cocoa contents affect blood glucose levels after consumption in healthy adults. Sixty healthy adults aged 18-35 years were randomly assigned to one of six groups: a control group or groups receiving chocolate containing 55%, 60%, 72%, 80%, or 90%… Read more about this study
- Who is it for?
- Ages 18 to 35 yearsHealthy volunteers can take part
- Conditions the study is for
- Postprandial Glycemic Response
- What is being tested?
- 55% Cocoa Chocolate, 60% Cocoa Chocolate and 72% Cocoa Chocolate
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 60 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 20 Mar 2023to 20 Sep 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 35 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- Age 18-35 years No acute or chronic disease No regular medication use Not currently following a weight-loss diet Not menstruating at the time of the study procedures Willing to participate and providing informed consent
Who cannot join
- History of bariatric surgery Acute or chronic digestive or absorption disorders Tobacco or alcohol use Food allergy or intolerance Use of dietary supplements Professional athlete status or excessive physical activity Pregnancy or breastfeeding
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
Bandirma Onyedi Eylul University
Balıkesir, Bandırma, 10200
About this study
Official title: Acute Postprandial Glycemic Responses to Chocolates With Different Cocoa Content in Healthy Adults: A Translational Perspective
This randomized controlled study evaluated how chocolates with different cocoa contents affect blood glucose levels after consumption in healthy adults. Sixty healthy adults aged 18-35 years were randomly assigned to one of six groups: a control group or groups receiving chocolate containing 55%, 60%, 72%, 80%, or 90% cocoa. All participants consumed a standardized meal. Participants in the intervention groups then consumed 40 g of their assigned chocolate. Blood glucose was measured before chocolate consumption and at 15, 30, 60, 90, and 120 minutes afterward. The study aimed to compare postprandial blood glucose responses among chocolates with different cocoa contents.
- Conditions
- Postprandial Glycemic Response
- Being tested
- 55% Cocoa Chocolate, 60% Cocoa Chocolate, 72% Cocoa Chocolate, 80% Cocoa Chocolate, 90% Cocoa Chocolate
- Keywords
- Chocolate, Cocoa, Blood Glucose, Postprandial Glycemia, Cocoa Content
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
55% Cocoa ChocolateOther
A single 40-g serving of commercially available chocolate containing 55% cocoa was consumed 30 minutes after the standardized meal.
60% Cocoa ChocolateOther
A single 40-g serving of commercially available chocolate containing 60% cocoa was consumed 30 minutes after the standardized meal.
72% Cocoa ChocolateOther
A single 40-g serving of commercially available chocolate containing 72% cocoa was consumed 30 minutes after the standardized meal.
80% Cocoa ChocolateOther
A single 40-g serving of commercially available chocolate containing 80% cocoa was consumed 30 minutes after the standardized meal.
90% Cocoa ChocolateOther
A single 40-g serving of commercially available chocolate containing 90% cocoa was consumed 30 minutes after the standardized meal.
| Study group | Role | What they receive |
|---|---|---|
| Control Group | No intervention | Participants consumed the standardized meal but did not receive chocolate. Blood glucose levels were measured at the same time points as in the intervention groups over the 120-minute follow-up period. |
| 55% Cocoa Chocolate Group | Experimental | Participants consumed a standardized meal followed 30 minutes later by a single 40-g serving of commercially available chocolate containing 55% cocoa. Blood glucose levels were measured before chocolate consumption (0 minutes) and at 15, 30, 60, 90, and 120 minutes after consumption. Receives: Other: 55% Cocoa Chocolate |
| 60% Cocoa Chocolate Group | Experimental | Participants consumed a standardized meal followed 30 minutes later by a single 40-g serving of commercially available chocolate containing 60% cocoa. Blood glucose levels were measured before chocolate consumption (0 minutes) and at 15, 30, 60, 90, and 120 minutes after consumption. Receives: Other: 60% Cocoa Chocolate |
| 72% Cocoa Chocolate Group | Experimental | Participants consumed a standardized meal followed 30 minutes later by a single 40-g serving of commercially available chocolate containing 72% cocoa. Blood glucose levels were measured before chocolate consumption (0 minutes) and at 15, 30, 60, 90, and 120 minutes after consumption. Receives: Other: 72% Cocoa Chocolate |
| 80% Cocoa Chocolate Group | Experimental | Participants consumed a standardized meal followed 30 minutes later by a single 40-g serving of commercially available chocolate containing 80% cocoa. Blood glucose levels were measured before chocolate consumption (0 minutes) and at 15, 30, 60, 90, and 120 minutes after consumption. Receives: Other: 80% Cocoa Chocolate |
| 90% Cocoa Chocolate Group | Experimental | Participants consumed a standardized meal followed 30 minutes later by a single 40-g serving of commercially available chocolate containing 90% cocoa. Blood glucose levels were measured before chocolate consumption (0 minutes) and at 15, 30, 60, 90, and 120 minutes after consumption. Receives: Other: 90% Cocoa Chocolate |
What is being measured
The primary outcome is the main question the study is designed to answer.
Postprandial Blood Glucose Levels
Blood glucose levels were measured using a glucometer before chocolate consumption (0 minutes) and at 15, 30, 60, 90, and 120 minutes after consumption. Blood glucose levels were compared across the control group and the five chocolate groups containing 55%, 60%, 72%, 80%, and 90% cocoa.
Measured: 0, 15, 30, 60, 90, and 120 minutes after chocolate consumption
Secondary outcomes (1)
Peak Blood Glucose
The maximum blood glucose level observed during the 0-120-minute postprandial measurement period was determined for each participant and compared across study groups.
Measured: During the 0-120-minute postprandial period
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted2 Oct 2026
- Study start20 Mar 2023
- Primary completion20 Mar 2025
- Study completion20 Sep 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Postprandial Glycemic ResponseStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Participant, Outcomes assessor
- Enrolment
- 60 participants (actual)
Sponsor and investigators
- Lead sponsor
- Bandırma Onyedi Eylül University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Yasemin Ergül, Bandırma Onyedi Eylül University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07855744
- Sponsor's protocol ID
- BAP-24-1003-015
- Status last verified
- Sep 2026
- First submitted
- 28 Sep 2026
- Last updated
- 2 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 2 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Acute Postprandial Glycemic Responses to Chocolates With Different Cocoa Content in Healthy Adults: A Translational Perspective
- ClinicalTrials.gov ID
- NCT07855744
- Acronym / sponsor ID
- BAP-24-1003-015
- Conditions
- Postprandial Glycemic Response
- Keywords
- Chocolate, Cocoa, Blood Glucose, Postprandial Glycemia, Cocoa Content
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 60 participants (actual)
- Lead sponsor
- Bandırma Onyedi Eylül UniversityUniversity, hospital or other
- Study start
- 20 Mar 2023 (actual)
- Primary completion
- 20 Mar 2025 (actual)
- Study completion
- 20 Sep 2026 (actual)
- First posted
- 2 Oct 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This randomized controlled study evaluated how chocolates with different cocoa contents affect blood glucose levels after consumption in healthy adults. Sixty healthy adults aged 18-35 years were randomly assigned to one of six groups: a control group or groups receiving chocolate containing 55%, 60%, 72%, 80%, or 90% cocoa. All participants consumed a standardized meal. Participants in the intervention groups then consumed 40 g of their assigned chocolate. Blood glucose was measured before chocolate consumption and at 15, 30, 60, 90, and 120 minutes afterward. The study aimed to compare postprandial blood glucose responses among chocolates with different cocoa contents.
Study design
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, outcomes assessor)
- Number of arms
- 6
| Arm | Type | Receives |
|---|---|---|
| Control Group | No intervention | –Participants consumed the standardized meal but did not receive chocolate. Blood glucose levels were measured at the same time points as in the intervention groups over the 120-minute follow-up period. |
| 55% Cocoa Chocolate Group | Experimental | Other: 55% Cocoa ChocolateParticipants consumed a standardized meal followed 30 minutes later by a single 40-g serving of commercially available chocolate containing 55% cocoa. Blood glucose levels were measured before chocolate consumption (0 minutes) and at 15, 30, 60, 90, and 120 minutes after consumption. |
| 60% Cocoa Chocolate Group | Experimental | Other: 60% Cocoa ChocolateParticipants consumed a standardized meal followed 30 minutes later by a single 40-g serving of commercially available chocolate containing 60% cocoa. Blood glucose levels were measured before chocolate consumption (0 minutes) and at 15, 30, 60, 90, and 120 minutes after consumption. |
| 72% Cocoa Chocolate Group | Experimental | Other: 72% Cocoa ChocolateParticipants consumed a standardized meal followed 30 minutes later by a single 40-g serving of commercially available chocolate containing 72% cocoa. Blood glucose levels were measured before chocolate consumption (0 minutes) and at 15, 30, 60, 90, and 120 minutes after consumption. |
| 80% Cocoa Chocolate Group | Experimental | Other: 80% Cocoa ChocolateParticipants consumed a standardized meal followed 30 minutes later by a single 40-g serving of commercially available chocolate containing 80% cocoa. Blood glucose levels were measured before chocolate consumption (0 minutes) and at 15, 30, 60, 90, and 120 minutes after consumption. |
| 90% Cocoa Chocolate Group | Experimental | Other: 90% Cocoa ChocolateParticipants consumed a standardized meal followed 30 minutes later by a single 40-g serving of commercially available chocolate containing 90% cocoa. Blood glucose levels were measured before chocolate consumption (0 minutes) and at 15, 30, 60, 90, and 120 minutes after consumption. |
Who may qualify
- Ages
- 18 to 35 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (1 listed)
- Age 18-35 years No acute or chronic disease No regular medication use Not currently following a weight-loss diet Not menstruating at the time of the study procedures Willing to participate and providing informed consent
Key exclusion criteria (1 listed)
- History of bariatric surgery Acute or chronic digestive or absorption disorders Tobacco or alcohol use Food allergy or intolerance Use of dietary supplements Professional athlete status or excessive physical activity Pregnancy or breastfeeding
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| 55% Cocoa ChocolateA single 40-g serving of commercially available chocolate containing 55% cocoa was consumed 30 minutes after the standardized meal. | Other | 55% Cocoa Chocolate Group |
| 60% Cocoa ChocolateA single 40-g serving of commercially available chocolate containing 60% cocoa was consumed 30 minutes after the standardized meal. | Other | 60% Cocoa Chocolate Group |
| 72% Cocoa ChocolateA single 40-g serving of commercially available chocolate containing 72% cocoa was consumed 30 minutes after the standardized meal. | Other | 72% Cocoa Chocolate Group |
| 80% Cocoa ChocolateA single 40-g serving of commercially available chocolate containing 80% cocoa was consumed 30 minutes after the standardized meal. | Other | 80% Cocoa Chocolate Group |
| 90% Cocoa ChocolateA single 40-g serving of commercially available chocolate containing 90% cocoa was consumed 30 minutes after the standardized meal. | Other | 90% Cocoa Chocolate Group |
Primary outcome
Postprandial Blood Glucose Levels
Time frame: 0, 15, 30, 60, 90, and 120 minutes after chocolate consumption
Blood glucose levels were measured using a glucometer before chocolate consumption (0 minutes) and at 15, 30, 60, 90, and 120 minutes after consumption. Blood glucose levels were compared across the control group and the five chocolate groups containing 55%, 60%, 72%, 80%, and 90% cocoa.
1 secondary outcome
Peak Blood Glucose
Time frame: During the 0-120-minute postprandial period
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 2 Oct 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing 55% Cocoa Chocolate, 60% Cocoa Chocolate and 72% Cocoa Chocolate in people with Postprandial Glycemic Response, run by Bandırma Onyedi Eylül University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 2 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Postprandial Blood Glucose Levels (time frame: 0, 15, 30, 60, 90, and 120 minutes after chocolate consumption). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 2 Oct 2026.