One-lung Ventilation (OLV)OLV-VENTNCT07866170
Comparison of Different Ventilation Modes in Video-Assisted Thoracoscopic Lung Resection
An observational study of One-lung Ventilation (OLV) and Video-assisted Thoracis Surgery (VATS), run by Ankara Ataturk Sanatorium Training and Research Hospital at 1 site in Turkey (Türkiye).
Trial summary
One-lung ventilation (OLV) is required for video-assisted thoracoscopic surgery (VATS) lung resection, but it exposes the dependent lung to atelectasis, high driving pressures, and oxidative stress, and is associated with postoperative pulmonary complications. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- One-lung Ventilation (OLV), Video-assisted Thoracis Surgery (VATS)
- How many people
- 120 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 12 Oct 2026to 3 Sep 2027
- How long will I take part?
- 1 Year
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Patients aged 18 years and older, ASA physical status I-III, scheduled for elective lung resection by video-assisted thoracoscopic surgery (VATS) with planned one-lung ventilation under total intravenous anesthesia at a single tertiary center. Patients are assigned to one of three groups according to the ventilation mode selected by the attending anesthesiologist (FCV, VCV, or PCV); no randomization is performed.
Who may be able to join
- -Age 18 years and older
- American Society of Anesthesiologists (ASA) physical status I, II, or III
- Scheduled for elective lung resection by video-assisted thoracoscopic surgery (VATS)
- Planned one-lung ventilation
- GOLD 2026 group 1 or group 2
- Planned total intravenous anesthesia (TIVA)
- Willing to participate and provides written informed consent
Who cannot join
- ASA physical status IV or older
- Emergency surgery
- Previous neoadjuvant chemotheraphy or radiotherapy
- GOLD 2026 group 3 or group 4
- Pneumothorax, pleural effusion or interstitial lung disease
- One-lung ventilation cannot be clinically maintained
Show all 9Show fewer
- Planned thoracotomy
- Incomplete data
- Refusal to participate
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Turkey (Türkiye)1 site
Ankara Ataturk Sanatoryum Education and Research Hospital
Ankara, 06290
Yenal ZORLU, +90-506-809-14-71, yenalzorlu@icloud.com
About this study
Official title: Comparison of Flow-Controlled, Volume-Controlled, and Pressure-Controlled Ventilation During One-Lung Ventilation in Video-Assisted Thoracoscopic Lung Resection: A Prospective Observational Study
One-lung ventilation (OLV) is required for video-assisted thoracoscopic surgery (VATS) lung resection, but it exposes the dependent lung to atelectasis, high driving pressures, and oxidative stress, and is associated with postoperative pulmonary complications. Volume-controlled ventilation (VCV) and pressure-controlled ventilation (PCV) are the conventional modes used during OLV. Flow-controlled ventilation (FCV) is a newer mode that delivers a constant gas flow during both inspiration and expiration through a narrow-bore endotracheal tube, and has been proposed to improve gas distribution and reduce mechanical stress on the lung.
This prospective observational study evaluates oxygenation and respiratory mechanics in adult patients undergoing elective VATS lung resection under OLV. The ventilation mode used for each patient is determined by the attending anaesthesiologist as part of routine clinical care, independently of the study; investigators do not participate in any aspect of patient management and collect data through observation only. Patients are grouped according to the mode used in clinical practice (FCV, VCV, or PCV).
The primary outcome is arterial oxygenation (PaO₂) at 30 minutes of OLV. Secondary outcomes include dynamic lung compliance, driving pressure, mechanical power, and haemodynamic parameters recorded at predefined intervals. A total of 120 patients (ASA I-III, GOLD stage 1-2) are planned for enrolment.
- Keywords
- Volume-Controlled Ventilation, Pressure-Controled Ventilation, Flow-Controlled Ventilation, Driving Pressure, Postoperative Complications, Mechanical Power
- Medical subject headings
- Postoperative Complications
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Flow-Controlled Ventilation | Patients ventilated with flow-controlled ventilation during one-lung ventilation, as selected by the attending anaesthesiologist | |
| Volume-Controlled Ventilation | Patients ventilated with volume-controlled ventilation during one-lung ventilation, as selected by the attending anaesthesiologist | |
| Pressure-Controlled Ventilation | Patients ventilated with pressure-controlled ventilation during one-lung ventilation, as selected by the attending anaesthesiologist |
What is being measured
The primary outcome is the main question the study is designed to answer.
Partial pressure of oxygen (PaO₂) during one-lung ventilation
PaO₂ in mmHg obtained from arterial blood gas analysis of a radial artery sample, measured at 30 minutes after the initiation of one-lung ventilation, with FiO₂ recorded simultaneously
Measured: 30-minutes after initiation of one-lung ventilation
Secondary outcomes (19)
PaO₂/FiO₂ ratio
Ratio of the partial pressure of arterial oxygen to the inspired oxygen fraction, calculated from arterial blood gas analysis.
Measured: 0 and 30 minutes after initiation of one-lung ventilation, and immediately before resumption of two-lung ventilation, up to 240 minutes
Partial pressure of arterial carbon dioxide (PaCO₂)
PaCO₂ in mmHg obtained from arterial blood gas analysis.
Measured: 0 and 30 minutes after initiation of one-lung ventilation, and immediately before resumption of two-lung ventilation, up to 240 minutes
Dynamic Compliance
Dynamic compliance obtained from ventilator readings
Measured: 0 and 30 minutes after initiation of one-lung ventilation, and immediately before resumption of two-lung ventilation, up to 240 minutes
Pleteau Pressure
Pleteau pressure obtained from ventilator readings
Measured: 0 and 30 minutes after initiation of one-lung ventilation, and immediately before resumption of two-lung ventilation, up to 240 minutes
Driving Pressure
Driving pressure obtained form ventilator settings
Measured: 0 and 30 minutes after initiation of one-lung ventilation, and immediately before resumption of two-lung ventilation, up to 240 minutes
Mechanical Power
Mechanical power (J/min) obtained and calculated form ventilator settings
Measured: 0 and 30 minutes after initiation of one-lung ventilation, and immediately before resumption of two-lung ventilation, up to 240 minutes
Peak Inspiratory Pressure
Peak inspiratory pressure obtained form ventilator settings
Measured: 0 and 30 minutes after initiation of one-lung ventilation, and immediately before resumption of two-lung ventilation, up to 240 minutes
Mean Airway Pressure
Mean airway pressure obtained and calculated form ventilator readings
Measured: 0 and 30 minutes after initiation of one-lung ventilation, and immediately before resumption of two-lung ventilation, up to 240 minutes
Systolic Arterial Pressure
Systolic arterial pressure (mmHg) measured by invasive arterial monitoring
Measured: 0 and 30 minutes after initiation of one-lung ventilation, and immediately before resumption of two-lung ventilation, up to 240 minutes
Diastolic Arterial Pressure
Diastolic arterial pressure (mmHg) measured by invasive arterial monitoring
Measured: 0 and 30 minutes after initiation of one-lung ventilation, and immediately before resumption of two-lung ventilation, up to 240 minutes
Heart Rate
Heart rate (beats per minute) measured by continuous electrocardiographic monitoring
Measured: 0 and 30 minutes after initiation of one-lung ventilation, and immediately before resumption of two-lung ventilation, up to 240 minutes
Mean Arterial Pressure
Mean arterial pressure (mmHg) measured by invasive arterial monitoring
Measured: 0 and 30 minutes after initiation of one-lung ventilation, and immediately before resumption of two-lung ventilation, up to 240 minutes
Peripheral Oxygen Saturation
Peripheral oxygen saturation (SpO₂, %), measured by pulse oximetry
Measured: 0 and 30 minutes after initiation of one-lung ventilation, and immediately before resumption of two-lung ventilation, up to 240 minutes
pH
pH obtained by arterial blood gas analysis
Measured: 0 and 30 minutes after initiation of one-lung ventilation, and immediately before resumption of two-lung ventilation, up to 240 minutes
End-tidal CO₂
End-tidal CO₂ (mmHg), measured by capnography
Measured: 0 and 30 minutes after initiation of one-lung ventilation, and immediately before resumption of two-lung ventilation, up to 240 minutes
Tidal Volume
Tidal volume (mL), obtained from ventilator readings
Measured: 0 and 30 minutes after initiation of one-lung ventilation, and immediately before resumption of two-lung ventilation, up to 240 minutes
PEEP
PEEP (cmH₂O), obtained from ventilator readings
Measured: 0 and 30 minutes after initiation of one-lung ventilation, and immediately before resumption of two-lung ventilation, up to 240 minutes
Postoperative pulmonary complications
Composite incidence of respiratory infection, respiratory failure, bronchospasm, atelectasis, pleural effusion, pneumothorax and aspiration pneumonia, assessed during the postoperative hospital stay.
Measured: From end of surgery through postoperative day 7 or hospital discharge, whichever occurs first
Lenght of stay and readmission
Duration of intensive care stay, ward stay, total hospital stay and hospital readmission after discharge.
Measured: From date of surgery to date of hospital discharge, up to 30 days
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted8 Oct 2026
- Study start12 Oct 2026 (estimated)
- Primary completion3 Sep 2027 (estimated)
- Study completion3 Sep 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (5)Papers the sponsor has linked to this study.
- Other trials for One-lung Ventilation (OLV)Studies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 120 participants (estimated)
- Target duration
- 1 Year
Sponsor and investigators
- Lead sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
- Sponsor type
- Other government
- Responsible party
- Principal investigator, Yenal Zorlu, Ankara Ataturk Sanatorium Training and Research Hospital
- Investigators
- Yenal ZORLU, Principal investigator, Ankara Ataturk Sanatorium Training and Research Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07866170
- Sponsor's protocol ID
- FCV-OLV-2026-01
- Acronym
- OLV-VENT
- Status last verified
- Oct 2026
- First submitted
- 30 Aug 2026
- Last updated
- 8 Oct 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Van Oosten JP, Francovich JE, Somhorst P, van der Zee P, Endeman H, Gommers DAMPJ, Jonkman AH. Flow-controlled ventilation decreases mechanical power in postoperative ICU patients. Intensive Care Med Exp. 2024 Mar 19;12(1):30. doi: 10.1186/s40635-024-00616-9.
PubMed 38502268Uhlig C, Neto AS, van der Woude M, Kiss T, Wittenstein J, Shelley B, Scholes H, Hiesmayr M, Vidal Melo MF, Sances D, Coskunfirat N, Pelosi P, Schultz M, Gama de Abreu M; LAS VEGAS# investigators, Protective Ventilation Network (PROVEnet), Clinical Trial Network of the European Society of Anaesthesiology. Intraoperative mechanical ventilation practice in thoracic surgery patients and its association with postoperative pulmonary complications: results of a multicenter prospective observational study. BMC Anesthesiol. 2020 Jul 22;20(1):179. doi: 10.1186/s12871-020-01098-4.
PubMed 32698775Li XF, Jin L, Yang JM, Luo QS, Liu HM, Yu H. Effect of ventilation mode on postoperative pulmonary complications following lung resection surgery: a randomised controlled trial. Anaesthesia. 2022 Nov;77(11):1219-1227. doi: 10.1111/anae.15848. Epub 2022 Sep 6.
PubMed 36066107Wittenstein J, Scharffenberg M, Ran X, Keller D, Michler P, Tauer S, Theilen R, Kiss T, Bluth T, Koch T, Gama de Abreu M, Huhle R. Comparative effects of flow vs. volume-controlled one-lung ventilation on gas exchange and respiratory system mechanics in pigs. Intensive Care Med Exp. 2020 Dec 18;8(Suppl 1):24. doi: 10.1186/s40635-020-00308-0.
PubMed 33336305Abram J, Spraider P, Martini J, Velik-Salchner C, Dejaco H, Augustin F, Putzer G, Hell T, Barnes T, Enk D. Flow-controlled versus pressure-controlled ventilation in thoracic surgery with one-lung ventilation - A randomized controlled trial. J Clin Anesth. 2025 Apr;103:111785. doi: 10.1016/j.jclinane.2025.111785. Epub 2025 Feb 27.
PubMed 40020438
Study at a glance
From the registry record, last updated by the sponsor on 8 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparison of Flow-Controlled, Volume-Controlled, and Pressure-Controlled Ventilation During One-Lung Ventilation in Video-Assisted Thoracoscopic Lung Resection: A Prospective Observational Study
- ClinicalTrials.gov ID
- NCT07866170
- Acronym / sponsor ID
- OLV-VENT / FCV-OLV-2026-01
- Keywords
- Volume-Controlled Ventilation, Pressure-Controled Ventilation, Flow-Controlled Ventilation, Driving Pressure, Postoperative Complications, Mechanical Power
- Study type
- Observational
- Recruitment status
- Not yet recruiting
- Enrolment
- 120 participants (estimated)
- Lead sponsor
- Ankara Ataturk Sanatorium Training and Research HospitalOther government
- Study start
- 12 Oct 2026 (estimated)
- Primary completion
- 3 Sep 2027 (estimated)
- Study completion
- 3 Sep 2027 (estimated)
- First posted
- 8 Oct 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
One-lung ventilation (OLV) is required for video-assisted thoracoscopic surgery (VATS) lung resection, but it exposes the dependent lung to atelectasis, high driving pressures, and oxidative stress, and is associated with postoperative pulmonary complications. Volume-controlled ventilation (VCV) and pressure-controlled ventilation (PCV) are the conventional modes used during OLV. Flow-controlled ventilation (FCV) is a newer mode that delivers a constant gas flow during both inspiration and expiration through a narrow-bore endotracheal tube, and has been proposed to improve gas distribution and reduce mechanical stress on the lung.
This prospective observational study evaluates oxygenation and respiratory mechanics in adult patients undergoing elective VATS lung resection under OLV. The ventilation mode used for each patient is determined by the attending anaesthesiologist as part of routine clinical care, independently of the study; investigators do not participate in any aspect of patient management and collect data through observation only. Patients are grouped according to the mode used in clinical practice (FCV, VCV, or PCV).
The primary outcome is arterial oxygenation (PaO₂) at 30 minutes of OLV. Secondary outcomes include dynamic lung compliance, driving pressure, mechanical power, and haemodynamic parameters recorded at predefined intervals. A total of 120 patients (ASA I-III, GOLD stage 1-2) are planned for enrolment.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Target follow-up
- 1 Year
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| Flow-Controlled Ventilation | – | –Patients ventilated with flow-controlled ventilation during one-lung ventilation, as selected by the attending anaesthesiologist |
| Volume-Controlled Ventilation | – | –Patients ventilated with volume-controlled ventilation during one-lung ventilation, as selected by the attending anaesthesiologist |
| Pressure-Controlled Ventilation | – | –Patients ventilated with pressure-controlled ventilation during one-lung ventilation, as selected by the attending anaesthesiologist |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Patients aged 18 years and older, ASA physical status I-III, scheduled for elective lung resection by video-assisted thoracoscopic surgery (VATS) with planned one-lung ventilation under total intravenous anesthesia at a single tertiary center. Patients are assigned to one of three groups according to the ventilation mode selected by the attending anesthesiologist (FCV, VCV, or PCV); no randomization is performed.
Key inclusion criteria (7 listed)
- -Age 18 years and older
- American Society of Anesthesiologists (ASA) physical status I, II, or III
- Scheduled for elective lung resection by video-assisted thoracoscopic surgery (VATS)
- Planned one-lung ventilation
- GOLD 2026 group 1 or group 2
Key exclusion criteria (9 listed)
- ASA physical status IV or older
- Emergency surgery
- Previous neoadjuvant chemotheraphy or radiotherapy
- GOLD 2026 group 3 or group 4
- Pneumothorax, pleural effusion or interstitial lung disease
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Partial pressure of oxygen (PaO₂) during one-lung ventilation
Time frame: 30-minutes after initiation of one-lung ventilation
PaO₂ in mmHg obtained from arterial blood gas analysis of a radial artery sample, measured at 30 minutes after the initiation of one-lung ventilation, with FiO₂ recorded simultaneously
19 secondary outcomes
PaO₂/FiO₂ ratio
Time frame: 0 and 30 minutes after initiation of one-lung ventilation, and immediately before resumption of two-lung ventilation, up to 240 minutes
Partial pressure of arterial carbon dioxide (PaCO₂)
Time frame: 0 and 30 minutes after initiation of one-lung ventilation, and immediately before resumption of two-lung ventilation, up to 240 minutes
Dynamic Compliance
Time frame: 0 and 30 minutes after initiation of one-lung ventilation, and immediately before resumption of two-lung ventilation, up to 240 minutes
Pleteau Pressure
Time frame: 0 and 30 minutes after initiation of one-lung ventilation, and immediately before resumption of two-lung ventilation, up to 240 minutes
Driving Pressure
Time frame: 0 and 30 minutes after initiation of one-lung ventilation, and immediately before resumption of two-lung ventilation, up to 240 minutes
Mechanical Power
Time frame: 0 and 30 minutes after initiation of one-lung ventilation, and immediately before resumption of two-lung ventilation, up to 240 minutes
Peak Inspiratory Pressure
Time frame: 0 and 30 minutes after initiation of one-lung ventilation, and immediately before resumption of two-lung ventilation, up to 240 minutes
Mean Airway Pressure
Time frame: 0 and 30 minutes after initiation of one-lung ventilation, and immediately before resumption of two-lung ventilation, up to 240 minutes
Systolic Arterial Pressure
Time frame: 0 and 30 minutes after initiation of one-lung ventilation, and immediately before resumption of two-lung ventilation, up to 240 minutes
Diastolic Arterial Pressure
Time frame: 0 and 30 minutes after initiation of one-lung ventilation, and immediately before resumption of two-lung ventilation, up to 240 minutes
Heart Rate
Time frame: 0 and 30 minutes after initiation of one-lung ventilation, and immediately before resumption of two-lung ventilation, up to 240 minutes
Mean Arterial Pressure
Time frame: 0 and 30 minutes after initiation of one-lung ventilation, and immediately before resumption of two-lung ventilation, up to 240 minutes
Peripheral Oxygen Saturation
Time frame: 0 and 30 minutes after initiation of one-lung ventilation, and immediately before resumption of two-lung ventilation, up to 240 minutes
pH
Time frame: 0 and 30 minutes after initiation of one-lung ventilation, and immediately before resumption of two-lung ventilation, up to 240 minutes
End-tidal CO₂
Time frame: 0 and 30 minutes after initiation of one-lung ventilation, and immediately before resumption of two-lung ventilation, up to 240 minutes
Tidal Volume
Time frame: 0 and 30 minutes after initiation of one-lung ventilation, and immediately before resumption of two-lung ventilation, up to 240 minutes
PEEP
Time frame: 0 and 30 minutes after initiation of one-lung ventilation, and immediately before resumption of two-lung ventilation, up to 240 minutes
Postoperative pulmonary complications
Time frame: From end of surgery through postoperative day 7 or hospital discharge, whichever occurs first
Lenght of stay and readmission
Time frame: From date of surgery to date of hospital discharge, up to 30 days
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 8 Oct 2026.
- Results publication: PubMed 38502268Van Oosten JP, Francovich JE, Somhorst P, van der Zee P, Endeman H, Gommers DAMPJ, Jonkman AH. Flow-controlled ventilation decreases mechanical power in postoperative ICU patients. Intensive Care Med Exp. 2024 Mar 19;12(1):30. doi: 10.1186/s40635-024-00616-9.
- Results publication: PubMed 32698775Uhlig C, Neto AS, van der Woude M, Kiss T, Wittenstein J, Shelley B, Scholes H, Hiesmayr M, Vidal Melo MF, Sances D, Coskunfirat N, Pelosi P, Schultz M, Gama de Abreu M; LAS VEGAS# investigators, Protective Ventilation Network (PROVEnet), Clinical Trial Network of the European Society of Anaesthesiology. Intraoperative mechanical ventilation practice in thoracic surgery patients and its association with postoperative pulmonary complications: results of a multicenter prospective observational study. BMC Anesthesiol. 2020 Jul 22;20(1):179. doi: 10.1186/s12871-020-01098-4.
- Results publication: PubMed 36066107Li XF, Jin L, Yang JM, Luo QS, Liu HM, Yu H. Effect of ventilation mode on postoperative pulmonary complications following lung resection surgery: a randomised controlled trial. Anaesthesia. 2022 Nov;77(11):1219-1227. doi: 10.1111/anae.15848. Epub 2022 Sep 6.
- Results publication: PubMed 33336305Wittenstein J, Scharffenberg M, Ran X, Keller D, Michler P, Tauer S, Theilen R, Kiss T, Bluth T, Koch T, Gama de Abreu M, Huhle R. Comparative effects of flow vs. volume-controlled one-lung ventilation on gas exchange and respiratory system mechanics in pigs. Intensive Care Med Exp. 2020 Dec 18;8(Suppl 1):24. doi: 10.1186/s40635-020-00308-0.
- Results publication: PubMed 40020438Abram J, Spraider P, Martini J, Velik-Salchner C, Dejaco H, Augustin F, Putzer G, Hell T, Barnes T, Enk D. Flow-controlled versus pressure-controlled ventilation in thoracic surgery with one-lung ventilation - A randomized controlled trial. J Clin Anesth. 2025 Apr;103:111785. doi: 10.1016/j.jclinane.2025.111785. Epub 2025 Feb 27.
- Individual participant dataSharing planned: No
Related trials for One-lung Ventilation (OLV)
RecruitingObservational study
Frequency and Severity of Respiratory Acidosis During One-lung Ventilation, a Retrospective Pilot Study to Compare Clinician Settings and Those Proposed by the VentilO Application
Thoracic, Surgery
Active, not recruitingObservational study
The Effect of Single Lung Ventilation Duration and Intraoperative Brain Oxygenation on Cognitive Function and Postoperative Pain in Geriatric Patients
Thoracic Anesthesia, Geriatric Anesthesia
Recruiting
Hyperangulated vs Standard Videolaryngoscopy vs Direct Laryngoscopy for Double-Lumen Endobronchial Tube Intubation
Endobronchial Intubation, Double Lumen Tube Intubation
Recruiting
BMI-Adjusted PEEP During One-Lung Ventilation in Thoracic Surgery
Pulmonary Resection Surgery, One Lung Ventillation (OLV)
Enrolling by invitationObservational study
Spontaneous Breathing Mode: A Risk for Hypoxemia During OLV?
Lung Cancer, OLV
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Ankara Ataturk Sanatoryum Education and Research Hospital
Ankara, Turkey (Türkiye)
Yenal ZORLU principal investigator
Ankara Ataturk Sanatorium Training and Research Hospital
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of One-lung Ventilation (OLV) and Video-assisted Thoracis Surgery (VATS), run by Ankara Ataturk Sanatorium Training and Research Hospital at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 7 inclusion and 9 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 8 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Each site lists its own contact: choose the nearest one under Trial locations. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Partial pressure of oxygen (PaO₂) during one-lung ventilation (time frame: 30-minutes after initiation of one-lung ventilation). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07866170, which also lists 5 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 8 Oct 2026.