Supraspinatus TendinitisNCT07873528
Anatomical Evaluation of Supraspinatus Through Ultrasonography and Biomechanical Measurements Following Blood Flow Restriction Therapy and Eccentric Exercise in Patients of Supraspinatus Tendinitis.
A study testing Blood flow restriction therapy, Eccentric Training and BFRT +ET in people with Supraspinatus Tendinitis, run by Sehat Medical Complex at 1 site in Pakistan.
Trial summary
Patients of both gender groups with unilateral shoulder pain will be selected with age range 40-60 years from Sehat medical complex and randomly allocated into four groups (Group A, B, C and D) in Trial. The sample size will be 60 patients. Read more about this study
- Who is it for?
- Ages 40 to 60 years
- Conditions the study is for
- Supraspinatus Tendinitis
- What is being tested?
- Blood flow restriction therapy, Eccentric Training and BFRT +ET
- Type of treatment
- Medical device
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 60 participants
- Where
- 1 sitePakistan
- Study dates
- 23 Dec 2026to 31 Dec 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 40 to 60 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Patient age 40-60 years with unilateral shoulder.
- Patient with at least two positive test (Empty Can, Hawkins-Kendy and Neer impingement test) in sitting and standing position will be enrolled.
- Patient with shoulder pain history up to three months.
- The shoulder pain on NPRS will be above or equal to 5 for the recruitment.
- Both male and female population.
- People who have not received any physical therapy treatment or exercise regimen for the past 3 months for upper limb injury or disease.
Who cannot join
- Patients with referred shoulder pain, systemic musculoskeletal pathology e.g., neurogenic, visceral referred pain.
- Full thickness tear of rotator cuff muscle or tendons.
- Patients with frozen shoulder pain or limited range of motion < 90degree shoulder abduction.
- Patients with previous shoulder surgery, intra articular injection, nerve block to shoulder last 6 month.
- Pregnant woman or 6-month recent history of pregnancy.
- Patient with history of blood pressure >180mmHg systolic.
- Patients with recent history of upper limb fracture, open wound, history of vascular surgery, uncontrolled diabetes and fistula in upper limb.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Sahar Ijaz, PhD Anatomy contact
Pakistan1 site, 1 recruiting
- Recruiting
Sehat Medical Complex/UOL/UVAS
Lahore, Punjab Province, 54000
Imran Ghafoor, 03344292887, imran.ghafoor64@gmail.com
About this study
Official title: Anatomical Evaluation of Supraspinatus Through Ultrasonography and Biomechanical Measurements Following Different Combinations of Physical Therapies in Patients of Supraspinatus Tendinitis.
Patients of both gender groups with unilateral shoulder pain will be selected with age range 40-60 years from Sehat medical complex and randomly allocated into four groups (Group A, B, C and D) in Trial. The sample size will be 60 patients. Musculoskeletal ultrasound, goniometry, pain pressure threshold, dynamometer and functional indices will be used to measure the tendon thickness, range of motion, pain, muscle strength and function level.
Read the detailed description
Supraspinatus will be evaluated for the combined effect of blood flow restriction therapy (BFRT) and Shock wave Therapy in Group C in comparison to BFRT alone in Group A, Eccenteric Training alone in Group B and routine physical therapy in Group D (Control Group).
- Conditions
- Supraspinatus Tendinitis
- Being tested
- Blood flow restriction therapy, Eccentric Training, BFRT +ET, RPT
- Keywords
- BFRT, ET, SST, RPT
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Blood flow restriction therapyDevice
Also called BFRT
4 Sets of exercise with restriction cuff 30,15,15,15 (75) with cable Pulley system.
The movement performed in scaption, external rotation and shoulder abduction.
Eccentric TrainingOther
Also called ET
4 Sets of exercise with Dumbbell or TheraBand 15,15,15, 15. Three sets of exercise with Abduction and External Rotation Movement.
3 session/week for 12 week The movement performed in scaption, external rotation and shoulder abduction.
BFRT +ETDevice
Also called BFRT+ET
Combination of A \& B
RPTOther
Electric Heating Pad (Besmed, Taiwan) 10 minutes, TENS (Comfy Stim, Taiwan Model #: EV-806) 10 minutes Isometric Shoulder Exercise 10 rep/3 sets
| Study group | Role | What they receive |
|---|---|---|
| Group A (Blood Flow Restriction Therapy) | Experimental | 4 Sets of exercise with restriction cuff 30,15,15,15 (75) with cable Pulley system.
The movement performed in scaption, external rotation and shoulder abduction. Receives: Device: Blood flow restriction therapy |
| Group B (Eccentric training) | Experimental | 4 Sets of exercise with Dumbbell or TheraBand 15,15,15, 15. Three sets of exercise with Abduction and External Rotation Movement.
3 session/week for 12 week The movement performed in scaption, external rotation and shoulder abduction. Receives: Other: Eccentric Training |
| Group C (Combination of BFRT+ET) | Experimental | Combination of both group A and group B Receives: Device: BFRT +ET |
| Group D | Sham comparator | Electric Heating Pad (Besmed, Taiwan) 10 minutes, TENS (Comfy Stim, Taiwan Model #: EV-806) 10 minutes Isometric Shoulder Exercise 10 rep/3 sets Receives: Other: RPT |
What is being measured
The primary outcome is the main question the study is designed to answer.
MSK Ultrasound
Supraspinatus Tendon thickness in long and short axis, These will be measureed in mili meter (mm) on Musculoskeletal Ultrasound with modified Crass psotion.
Measured: 12 weeks (Baseline, 4 weeks, 8 Weeks, and 12 Weeks)
Shoulder pain
Numeric Pain Rating Scale for Pain, (0-10 unit scale, 0 mean NO Pain and 10 means imaginable worset pain)
Measured: 12 weeks (data will be collected at Baseline, 4 weeks, 8 Weeks, and 12 Weeks)
Shoulder Joint ROM
ROM measurement with Goniometer (Universal 360 degree and bubble goniometer will be used
Measured: 12 weeks (data will be collected at Baseline, 4 weeks, 8 Weeks, and 12 Weeks)
Secondary outcomes (4)
Shoulder Joint function and disability
shoulder joint function and disability will be measured by Disability of arm, shoulder and hand sclae (Quick DASH) 0-100 0 means maximum function a person can perform, 100 means worst imaginable condition of disability. The Shoulder pain and Disability index (SPADI) scale is used to measre the pain and disability in shoulder conditions, scale range 0-100, 0 means maximum functionality and 100 means imagunable disability or worset condition.
Measured: 12 weeks (data will be collected at Baseline, 4 weeks, 8 Weeks, and 12 Weeks)
Shoulder Muscle Strength
1 Repetition Maximum of shoulder Abduction will be measure by Epleys method.
Measured: 12 weeks (data will be collected at Baseline, 4 weeks, 8 Weeks, and 12 Weeks)
Peripher pain sensitization
Pain pressure algometry will be used, The clinician places the tip of teh instrument perpendicular to the targeted muscle, and tendon and applies a steady, continuous increase in pressure (usually at a rate of 1 kg/cm² per second). the values will be measure in lb persecond or Newton.
Measured: 12 weeks (data will be collected at Baseline, 4 weeks, 8 Weeks, and 12 Weeks)
Shoulder Joint strength
Shoulder muscle strength measure through Hand Held Dynamometer, the instrumnet will measure the isomatric force of shoulder muscle in abduction, external rotation and internal rotation in Newton or Kilogram force.
Measured: 12 weeks (data will be collected at Baseline, 4 weeks, 8 Weeks, and 12 Weeks)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted14 Oct 2026
- Study start23 Dec 2026 (estimated)
- Primary completion31 Dec 2026 (estimated)
- Study completion31 Dec 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (9)Papers the sponsor has linked to this study.
- Other trials for Supraspinatus TendinitisStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- RCT with 4 Arm parallels design
- Masking
- Double blind
- Who is masked
- Investigator, Outcomes assessor
- Enrolment
- 60 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Sehat Medical Complex
- Sponsor type
- University, hospital or other
- Collaborators
- University of Veterinary and Animal Sciences, Lahore - Pakistan
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07873528
- Sponsor's protocol ID
- 434/IRC/BMR/30/12/2025
- Status last verified
- Oct 2026
- First submitted
- 15 Sep 2026
- Last updated
- 14 Oct 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: Patients of both gender groups with unilateral shoulder pain will be selected with age range 40-60 years from Sehat medical complex and randomly allocated into four groups (Group A, B, C and D). The sample size will be 60 patients . Musculoskeletal ultrasound, goniometry, pain pressure threshold, dynamometer and functional indices will be used to measure the tendon thickness, range of motion, pain, muscle strength and function level.
Publications
De Misa RF, Azana JM, Bellas C, Perez B, Rocamora A, Ledo A. Mycosis fungoides with signet-ring cells and monoclonal gammopathy. Int J Dermatol. 1994 Sep;33(9):652-3. doi: 10.1111/j.1365-4362.1994.tb02930.x. No abstract available.
PubMed 8002167Chew E, Lee Day A, Nazarian LN, Kohler M. Basic Musculoskeletal Ultrasound. Med Clin North Am. 2025 Jan;109(1):137-161. doi: 10.1016/j.mcna.2024.06.007. Epub 2024 Aug 3.
PubMed 39567090Dube MO, Ingwersen KG, Roy JS, Desmeules F, Lewis J, Juul-Kristensen B, Vobbe J, Jensen SL, McCreesh K. Do therapeutic exercises impact supraspinatus tendon thickness? Secondary analyses of the combined dataset from two randomized controlled trials in patients with rotator cuff-related shoulder pain. J Shoulder Elbow Surg. 2024 Sep;33(9):1918-1927. doi: 10.1016/j.jse.2024.03.055. Epub 2024 May 16.
PubMed 38762149Harrer J, Lonsky V, Dominik J, Zacek P, Sistek J, Harrerova L, Knap J. [Coronary revascularization in diffuse atherosclerosis of the anterior descending coronary artery]. Rozhl Chir. 1997 Jul;76(7):342-8. Czech.
PubMed 9446250Ackmann T, Schneider KN, Schorn D, Rickert C, Gosheger G, Liem D. Comparison of efficacy of supraspinatus tendon tears diagnostic tests: a prospective study on the "full-can," the "empty-can," and the "Whipple" tests. Musculoskelet Surg. 2021 Aug;105(2):149-153. doi: 10.1007/s12306-019-00631-0. Epub 2019 Nov 5.
PubMed 31691179Jones JW, McCullough LB. Consent for an intraoperative video record. J Vasc Surg. 2001 Dec;34(6):1133-4. doi: 10.1067/mva.2001.119949. No abstract available.
PubMed 11743574Kara D, Ozcakar L, Demirci S, Huri G, Duzgun I. Blood Flow Restriction Training in Patients With Rotator Cuff Tendinopathy: A Randomized, Assessor-Blinded, Controlled Trial. Clin J Sport Med. 2024 Jan 1;34(1):10-16. doi: 10.1097/JSM.0000000000001191. Epub 2023 Sep 14.
PubMed 37706671Yoshiura K, Stamatakis HC, Welander U, McDavid WD, Shi XQ, Ban S, Kawazu T, Tatsumi M, Kanda S. Physical evaluation of a system for direct digital intra-oral radiography based on a charge-coupled device. Dentomaxillofac Radiol. 1999 Sep;28(5):277-83. doi: 10.1038/sj/dmfr/4600457.
PubMed 10490745Lambert B, Hedt C, Daum J, Taft C, Chaliki K, Epner E, McCulloch P. Blood Flow Restriction Training for the Shoulder: A Case for Proximal Benefit. Am J Sports Med. 2021 Aug;49(10):2716-2728. doi: 10.1177/03635465211017524. Epub 2021 Jun 10.
PubMed 34110960
Study at a glance
From the registry record, last updated by the sponsor on 14 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Anatomical Evaluation of Supraspinatus Through Ultrasonography and Biomechanical Measurements Following Different Combinations of Physical Therapies in Patients of Supraspinatus Tendinitis.
- ClinicalTrials.gov ID
- NCT07873528
- Acronym / sponsor ID
- 434/IRC/BMR/30/12/2025
- Conditions
- Supraspinatus Tendinitis
- Keywords
- BFRT, ET, SST, RPT
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 60 participants (estimated)
- Lead sponsor
- Sehat Medical ComplexUniversity, hospital or other
- Collaborators
- University of Veterinary and Animal Sciences, Lahore - Pakistan
- Study start
- 23 Dec 2026 (estimated)
- Primary completion
- 31 Dec 2026 (estimated)
- Study completion
- 31 Dec 2026 (estimated)
- First posted
- 14 Oct 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Patients of both gender groups with unilateral shoulder pain will be selected with age range 40-60 years from Sehat medical complex and randomly allocated into four groups (Group A, B, C and D) in Trial. The sample size will be 60 patients. Musculoskeletal ultrasound, goniometry, pain pressure threshold, dynamometer and functional indices will be used to measure the tendon thickness, range of motion, pain, muscle strength and function level.
Detailed description
Supraspinatus will be evaluated for the combined effect of blood flow restriction therapy (BFRT) and Shock wave Therapy in Group C in comparison to BFRT alone in Group A, Eccenteric Training alone in Group B and routine physical therapy in Group D (Control Group).
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (investigator, outcomes assessor)
- Number of arms
- 4
- Model description
- RCT with 4 Arm parallels design
| Arm | Type | Receives |
|---|---|---|
| Group A (Blood Flow Restriction Therapy) | Experimental | Device: Blood flow restriction therapy4 Sets of exercise with restriction cuff 30,15,15,15 (75) with cable Pulley system. The movement performed in scaption, external rotation and shoulder abduction. |
| Group B (Eccentric training) | Experimental | Other: Eccentric Training4 Sets of exercise with Dumbbell or TheraBand 15,15,15, 15. Three sets of exercise with Abduction and External Rotation Movement. 3 session/week for 12 week The movement performed in scaption, external rotation and shoulder abduction. |
| Group C (Combination of BFRT+ET) | Experimental | Device: BFRT +ETCombination of both group A and group B |
| Group D | Sham comparator | Other: RPTElectric Heating Pad (Besmed, Taiwan) 10 minutes, TENS (Comfy Stim, Taiwan Model #: EV-806) 10 minutes Isometric Shoulder Exercise 10 rep/3 sets |
Who may qualify
- Ages
- 40 to 60 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (6 listed)
- Patient age 40-60 years with unilateral shoulder.
- Patient with at least two positive test (Empty Can, Hawkins-Kendy and Neer impingement test) in sitting and standing position will be enrolled.
- Patient with shoulder pain history up to three months.
- The shoulder pain on NPRS will be above or equal to 5 for the recruitment.
- Both male and female population.
Key exclusion criteria (7 listed)
- Patients with referred shoulder pain, systemic musculoskeletal pathology e.g., neurogenic, visceral referred pain.
- Full thickness tear of rotator cuff muscle or tendons.
- Patients with frozen shoulder pain or limited range of motion < 90degree shoulder abduction.
- Patients with previous shoulder surgery, intra articular injection, nerve block to shoulder last 6 month.
- Pregnant woman or 6-month recent history of pregnancy.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Blood flow restriction therapyAlso: BFRT4 Sets of exercise with restriction cuff 30,15,15,15 (75) with cable Pulley system. The movement performed in scaption, external rotation and shoulder abduction. | Device | Group A (Blood Flow Restriction Therapy) |
| Eccentric TrainingAlso: ET4 Sets of exercise with Dumbbell or TheraBand 15,15,15, 15. Three sets of exercise with Abduction and External Rotation Movement. 3 session/week for 12 week The movement performed in scaption, external rotation and shoulder abduction. | Other | Group B (Eccentric training) |
| BFRT +ETAlso: BFRT+ETCombination of A \& B | Device | Group C (Combination of BFRT+ET) |
| RPTElectric Heating Pad (Besmed, Taiwan) 10 minutes, TENS (Comfy Stim, Taiwan Model #: EV-806) 10 minutes Isometric Shoulder Exercise 10 rep/3 sets | Other | Group D |
Primary outcome
MSK Ultrasound
Time frame: 12 weeks (Baseline, 4 weeks, 8 Weeks, and 12 Weeks)
Supraspinatus Tendon thickness in long and short axis, These will be measureed in mili meter (mm) on Musculoskeletal Ultrasound with modified Crass psotion.
Shoulder pain
Time frame: 12 weeks (data will be collected at Baseline, 4 weeks, 8 Weeks, and 12 Weeks)
Numeric Pain Rating Scale for Pain, (0-10 unit scale, 0 mean NO Pain and 10 means imaginable worset pain)
Shoulder Joint ROM
Time frame: 12 weeks (data will be collected at Baseline, 4 weeks, 8 Weeks, and 12 Weeks)
ROM measurement with Goniometer (Universal 360 degree and bubble goniometer will be used
4 secondary outcomes
Shoulder Joint function and disability
Time frame: 12 weeks (data will be collected at Baseline, 4 weeks, 8 Weeks, and 12 Weeks)
Shoulder Muscle Strength
Time frame: 12 weeks (data will be collected at Baseline, 4 weeks, 8 Weeks, and 12 Weeks)
Peripher pain sensitization
Time frame: 12 weeks (data will be collected at Baseline, 4 weeks, 8 Weeks, and 12 Weeks)
Shoulder Joint strength
Time frame: 12 weeks (data will be collected at Baseline, 4 weeks, 8 Weeks, and 12 Weeks)
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 14 Oct 2026.
- Background: PubMed 8002167De Misa RF, Azana JM, Bellas C, Perez B, Rocamora A, Ledo A. Mycosis fungoides with signet-ring cells and monoclonal gammopathy. Int J Dermatol. 1994 Sep;33(9):652-3. doi: 10.1111/j.1365-4362.1994.tb02930.x. No abstract available.
- Background: PubMed 39567090Chew E, Lee Day A, Nazarian LN, Kohler M. Basic Musculoskeletal Ultrasound. Med Clin North Am. 2025 Jan;109(1):137-161. doi: 10.1016/j.mcna.2024.06.007. Epub 2024 Aug 3.
- Background: PubMed 38762149Dube MO, Ingwersen KG, Roy JS, Desmeules F, Lewis J, Juul-Kristensen B, Vobbe J, Jensen SL, McCreesh K. Do therapeutic exercises impact supraspinatus tendon thickness? Secondary analyses of the combined dataset from two randomized controlled trials in patients with rotator cuff-related shoulder pain. J Shoulder Elbow Surg. 2024 Sep;33(9):1918-1927. doi: 10.1016/j.jse.2024.03.055. Epub 2024 May 16.
- Background: PubMed 9446250Harrer J, Lonsky V, Dominik J, Zacek P, Sistek J, Harrerova L, Knap J. [Coronary revascularization in diffuse atherosclerosis of the anterior descending coronary artery]. Rozhl Chir. 1997 Jul;76(7):342-8. Czech.
- Background: PubMed 31691179Ackmann T, Schneider KN, Schorn D, Rickert C, Gosheger G, Liem D. Comparison of efficacy of supraspinatus tendon tears diagnostic tests: a prospective study on the "full-can," the "empty-can," and the "Whipple" tests. Musculoskelet Surg. 2021 Aug;105(2):149-153. doi: 10.1007/s12306-019-00631-0. Epub 2019 Nov 5.
- Background: PubMed 11743574Jones JW, McCullough LB. Consent for an intraoperative video record. J Vasc Surg. 2001 Dec;34(6):1133-4. doi: 10.1067/mva.2001.119949. No abstract available.
- Background: PubMed 37706671Kara D, Ozcakar L, Demirci S, Huri G, Duzgun I. Blood Flow Restriction Training in Patients With Rotator Cuff Tendinopathy: A Randomized, Assessor-Blinded, Controlled Trial. Clin J Sport Med. 2024 Jan 1;34(1):10-16. doi: 10.1097/JSM.0000000000001191. Epub 2023 Sep 14.
- Background: PubMed 10490745Yoshiura K, Stamatakis HC, Welander U, McDavid WD, Shi XQ, Ban S, Kawazu T, Tatsumi M, Kanda S. Physical evaluation of a system for direct digital intra-oral radiography based on a charge-coupled device. Dentomaxillofac Radiol. 1999 Sep;28(5):277-83. doi: 10.1038/sj/dmfr/4600457.
- Background: PubMed 34110960Lambert B, Hedt C, Daum J, Taft C, Chaliki K, Epner E, McCulloch P. Blood Flow Restriction Training for the Shoulder: A Case for Proximal Benefit. Am J Sports Med. 2021 Aug;49(10):2716-2728. doi: 10.1177/03635465211017524. Epub 2021 Jun 10.
- Individual participant dataSharing planned: Yes. Patients of both gender groups with unilateral shoulder pain will be selected with age range 40-60 years from Sehat medical complex and randomly allocated into four groups (Group A, B, C and D). The sample size will be 60 patients . Musculoskeletal ultrasound, goniometry, pain pressure threshold, dynamometer and functional indices will be used to measure the tendon thickness, range of motion, pain, muscle strength and function level.
Related trials for Supraspinatus Tendinitis
Recruiting
Effects of Cervicothoracic Mobilization in Patients With Supraspinatus Tendinitis
Rotator Cuff Tendonitis
Recruiting
HILT vs ESWT in Supraspinatus Tendinitis
Supraspinatus Tendinitis
Recruiting
Reverse Fly Exercise On Supraspinatus Tendinitis In Patients Receiving Aromatase Inhibitors Therapy After Mastectomy
Mastectomy, Aromatase Inhibitors Therapy
Active, not recruiting
Anatomical Evaluation of Supraspinatus Through Ultrasonography and Biomechanical Measurements Following Different Combinations of Physical Therapies in Patients of Supraspinatus Tendinitis
Supraspinatus Tendinitis
Not yet recruiting
Effect of TECAR on Supraspinatus Tendon Thickness in Supraspinatus Tendinitis
Supraspinatus Tendonitis
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Sahar Ijaz, PhD Anatomy contact
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Blood flow restriction therapy, Eccentric Training and BFRT +ET in people with Supraspinatus Tendinitis, run by Sehat Medical Complex at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 14 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Dr Imran Ghafoor, M Phil (+923344292887, imran.ghafoor64@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
MSK Ultrasound (time frame: 12 weeks (Baseline, 4 weeks, 8 Weeks, and 12 Weeks)). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07873528, which also lists 9 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 14 Oct 2026.