Total Hip Arthroplasty, Postoperative PainNCT07879521
PENG, Suprainguinal Fascia Iliaca Block, and Control After Total Hip Arthroplasty
A study testing Pericapsular nerve group (PENG) block and Suprainguinal Fascia Iliaca Plane Block in people with Total Hip Arthroplasty, Postoperative Pain, run by Uludag University at 1 site in Turkey (Türkiye).
Trial summary
Total hip arthroplasty can cause significant pain after surgery. Regional anesthesia techniques, such as the pericapsular nerve group (PENG) block and the suprainguinal fascia iliaca plane block, may help reduce postoperative pain and opioid requirements. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Total Hip Arthroplasty, Postoperative Pain
- What is being tested?
- Pericapsular nerve group (PENG) block and Suprainguinal Fascia Iliaca Plane Block
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 99 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 2 Apr 2026to 29 Sep 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Patients who provided written informed consent
- Patients aged 18 years or older
- Patients with an American Society of Anesthesiologists (ASA) physical status of I, II, or III
- Patients scheduled to undergo elective total hip arthroplasty
Who cannot join
- Patients who did not consent to participate in the study
- Patients with ASA physical status IV or V
- Patients using anticoagulant medication or with suspected coagulopathy
- Patients with an allergy to local anesthetic agents
- Patients with infection at the intended block site
- Pregnant patients or patients with suspected pregnancy
Show all 10Show fewer
- Patients with severe neurological or psychiatric disorders
- Patients with severe cardiovascular disease
- Patients with chronic opioid use
- Patients with hepatic insufficiency or renal failure (glomerular filtration rate <15 mL/min/1.73 m²)
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
Bursa Uludağ University Faculty of Medicine Hospital
Bursa, Bursa
About this study
Official title: Comparison of the Effects of PENG and Fascia Iliaca Plane Blocks on Postoperative Analgesia and Muscle Strength in Total Hip Arthroplasty: A Randomized, Controlled, Prospective Study
Total hip arthroplasty can cause significant pain after surgery. Regional anesthesia techniques, such as the pericapsular nerve group (PENG) block and the suprainguinal fascia iliaca plane block, may help reduce postoperative pain and opioid requirements. However, these techniques may also affect muscle strength and early mobilization.
This randomized, controlled, prospective study compares the effects of PENG block, suprainguinal fascia iliaca plane block, and no regional block in patients undergoing total hip arthroplasty. Postoperative pain, opioid consumption, quadriceps muscle strength, and hip flexion are evaluated to compare the analgesic effectiveness and motor effects of these approaches.
- Being tested
- Pericapsular nerve group (PENG) block, Suprainguinal Fascia Iliaca Plane Block
- Keywords
- Total Hip Arthroplasty, PENG Block, Suprainguinal Fascia Iliaca Block, Postoperative Analgesia, Quadriceps Muscle Strength
- Medical subject headings
- Pain, Postoperative
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Pericapsular nerve group (PENG) blockProcedure or surgery
Ultrasound-guided pericapsular nerve group (PENG) block performed for postoperative analgesia in patients undergoing total hip arthroplasty.
Suprainguinal Fascia Iliaca Plane BlockProcedure or surgery
Ultrasound-guided suprainguinal fascia iliaca plane block performed for postoperative analgesia in patients undergoing total hip arthroplasty.
| Study group | Role | What they receive |
|---|---|---|
| PENG Block Group | Experimental | Participants undergoing total hip arthroplasty received a pericapsular nerve group (PENG) block for postoperative analgesia. Receives: Procedure: Pericapsular nerve group (PENG) block |
| Suprainguinal Fascia Iliaca Block Group | Experimental | Participants undergoing total hip arthroplasty received a suprainguinal fascia iliaca plane block for postoperative analgesia. Receives: Procedure: Suprainguinal Fascia Iliaca Plane Block |
| Control Group | No intervention | Participants undergoing total hip arthroplasty did not receive a regional nerve block. Standard perioperative care and analgesia were provided according to the study protocol. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Postoperative Pain Scores
Postoperative pain intensity was assessed using the visual analog scale (VAS), with scores recorded on a 0-100 mm scale. Pain scores were compared among the PENG block, suprainguinal fascia iliaca plane block, and control groups.
Measured: Up to 24 hours after surgery.
Secondary outcomes (2)
Quadriceps Muscle Strength
Quadriceps muscle strength was assessed using manual muscle testing (MMT).
Measured: Up to 24 hours after surgery.
Hip Flexion Angle
Hip flexion angle was measured in degrees.
Measured: Up to 24 hours after surgery.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted19 Oct 2026
- Study start2 Apr 2026
- Primary completion29 Sep 2026
- Study completion29 Sep 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Total Hip Arthroplasty, Postoperative PainStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Participant, Outcomes assessor
- Enrolment
- 99 participants (actual)
Sponsor and investigators
- Lead sponsor
- Uludag University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Berfin Altaş, Uludag University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07879521
- Sponsor's protocol ID
- 2026-3/9
- Status last verified
- Oct 2026
- First submitted
- 10 Oct 2026
- Last updated
- 19 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 19 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparison of the Effects of PENG and Fascia Iliaca Plane Blocks on Postoperative Analgesia and Muscle Strength in Total Hip Arthroplasty: A Randomized, Controlled, Prospective Study
- ClinicalTrials.gov ID
- NCT07879521
- Acronym / sponsor ID
- 2026-3/9
- Keywords
- Total Hip Arthroplasty, PENG Block, Suprainguinal Fascia Iliaca Block, Postoperative Analgesia, Quadriceps Muscle Strength
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 99 participants (actual)
- Lead sponsor
- Uludag UniversityUniversity, hospital or other
- Study start
- 2 Apr 2026 (actual)
- Primary completion
- 29 Sep 2026 (actual)
- Study completion
- 29 Sep 2026 (actual)
- First posted
- 19 Oct 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Total hip arthroplasty can cause significant pain after surgery. Regional anesthesia techniques, such as the pericapsular nerve group (PENG) block and the suprainguinal fascia iliaca plane block, may help reduce postoperative pain and opioid requirements. However, these techniques may also affect muscle strength and early mobilization.
This randomized, controlled, prospective study compares the effects of PENG block, suprainguinal fascia iliaca plane block, and no regional block in patients undergoing total hip arthroplasty. Postoperative pain, opioid consumption, quadriceps muscle strength, and hip flexion are evaluated to compare the analgesic effectiveness and motor effects of these approaches.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, outcomes assessor)
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| PENG Block Group | Experimental | Procedure: Pericapsular nerve group (PENG) blockParticipants undergoing total hip arthroplasty received a pericapsular nerve group (PENG) block for postoperative analgesia. |
| Suprainguinal Fascia Iliaca Block Group | Experimental | Procedure: Suprainguinal Fascia Iliaca Plane BlockParticipants undergoing total hip arthroplasty received a suprainguinal fascia iliaca plane block for postoperative analgesia. |
| Control Group | No intervention | –Participants undergoing total hip arthroplasty did not receive a regional nerve block. Standard perioperative care and analgesia were provided according to the study protocol. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- Patients who provided written informed consent
- Patients aged 18 years or older
- Patients with an American Society of Anesthesiologists (ASA) physical status of I, II, or III
- Patients scheduled to undergo elective total hip arthroplasty
Key exclusion criteria (10 listed)
- Patients who did not consent to participate in the study
- Patients with ASA physical status IV or V
- Patients using anticoagulant medication or with suspected coagulopathy
- Patients with an allergy to local anesthetic agents
- Patients with infection at the intended block site
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Pericapsular nerve group (PENG) blockUltrasound-guided pericapsular nerve group (PENG) block performed for postoperative analgesia in patients undergoing total hip arthroplasty. | Procedure or surgery | PENG Block Group |
| Suprainguinal Fascia Iliaca Plane BlockUltrasound-guided suprainguinal fascia iliaca plane block performed for postoperative analgesia in patients undergoing total hip arthroplasty. | Procedure or surgery | Suprainguinal Fascia Iliaca Block Group |
Primary outcome
Postoperative Pain Scores
Time frame: Up to 24 hours after surgery.
Postoperative pain intensity was assessed using the visual analog scale (VAS), with scores recorded on a 0-100 mm scale. Pain scores were compared among the PENG block, suprainguinal fascia iliaca plane block, and control groups.
2 secondary outcomes
Quadriceps Muscle Strength
Time frame: Up to 24 hours after surgery.
Hip Flexion Angle
Time frame: Up to 24 hours after surgery.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 19 Oct 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Pericapsular nerve group (PENG) block and Suprainguinal Fascia Iliaca Plane Block in people with Total Hip Arthroplasty, Postoperative Pain, run by Uludag University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 10 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 19 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Postoperative Pain Scores (time frame: Up to 24 hours after surgery.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 19 Oct 2026.