Anaerobic PerformanceNCT07903714
Hyperventilation and Post-Activation Performance Enhancement on Anaerobic Capacity
A study testing Voluntary Hyperventilation, Post-Activation Performance Enhancement (PAPE) and Wingate Anaerobic Test in people with Anaerobic Performance and Energy System Contributions, run by Manisa Celal Bayar University at 1 site in Turkey (Türkiye).
Trial summary
The purpose of this study is to investigate the independent and combined effects of post-activation performance enhancement (PAPE) and voluntary hyperventilation (HV) interventions on anaerobic power outputs, energy system contributions during a 30-second Wingate Anaerobic Test (WAnT). Read more about this study
- Who is it for?
- Ages 18 to 25 years, men onlyHealthy volunteers can take part
- Conditions the study is for
- Anaerobic Performance, Energy System Contributions, Hyperventilation
- What is being tested?
- Voluntary Hyperventilation, Post-Activation Performance Enhancement (PAPE) and Wingate Anaerobic Test
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 11 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 11 Feb 2026to 26 Feb 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 25 years
- Men only
- Healthy volunteers accepted
- Adult
Who may be able to join
None listed.
Who cannot join
- Current or recent orthopedic injuries that could negatively affect cycling performance
- Use of dietary supplements or performance-enhancing substances (e.g., creatine, caffeine, or bicarbonate) within the past four weeks
- Ongoing medical treatment that could affect metabolic or performance outcomes
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
Manisa Celal Bayar University, Faculty of Sport Sciences
Manisa
About this study
Official title: Acute Effects of Hyperventilation, Post-Activation Performance Enhancement, and Combined Protocols on Anaerobic Capacity and Energy System Contributions
The purpose of this study is to investigate the independent and combined effects of post-activation performance enhancement (PAPE) and voluntary hyperventilation (HV) interventions on anaerobic power outputs, energy system contributions during a 30-second Wingate Anaerobic Test (WAnT).
- Conditions
- Anaerobic Performance, Energy System Contributions, Hyperventilation, Post Activation Potentiation
- Being tested
- Voluntary Hyperventilation, Post-Activation Performance Enhancement (PAPE), Wingate Anaerobic Test
- Medical subject headings
- Hyperventilation
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Voluntary HyperventilationOther
Controlled breathing protocol performed prior to testing.
Post-Activation Performance Enhancement (PAPE)Other
Conditioning protocol applied prior to the Wingate test to potentiate subsequent anaerobic performance.
Wingate Anaerobic TestProcedure or surgery
30-second maximal anaerobic cycling test on a cycle ergometer.
| Study group | Role | What they receive |
|---|---|---|
| Control Session | Active comparator | Baseline 30-s Wingate test without prior intervention. Receives: Procedure: Wingate Anaerobic Test |
| Hyperventilation (HV) Session | Experimental | 30-s Wingate test preceded by voluntary hyperventilation. Receives: Other: Voluntary Hyperventilation; Procedure: Wingate Anaerobic Test |
| PAPE Session | Experimental | 30-s Wingate test preceded by PAPE protocol. Receives: Other: Post-Activation Performance Enhancement (PAPE); Procedure: Wingate Anaerobic Test |
| PAPE+HV Session | Experimental | 30-s Wingate test preceded by combined PAPE and hyperventilation protocols. Receives: Other: Voluntary Hyperventilation; Other: Post-Activation Performance Enhancement (PAPE); Procedure: Wingate Anaerobic Test |
What is being measured
The primary outcome is the main question the study is designed to answer.
Relative Peak Power (RPP)
Evaluation of relative peak power during the 30-second Wingate anaerobic test
Measured: During the 30-second Wingate anaerobic test
Relative Mean Power (RMP)
Evaluation of relative mean power during the 30-second Wingate anaerobic test.
Measured: During the 30-second Wingate anaerobic test
Fatigue Index (FI)
Evaluation of fatigue index during the 30-second Wingate anaerobic test.
Measured: During the 30-second Wingate anaerobic test
Secondary outcomes (6)
ATP-PCr Energy System Contribution (Absolute)
Evaluation of ATP-PCr energy system contribution in absolute terms (kJ), determined from the fast component of excess post-exercise oxygen consumption (EPOC) during recovery.
Measured: During the 5-minute post-exercise recovery period
ATP-PCr Energy System Contribution (Relative)
Evaluation of ATP-PCr energy system contribution in relative terms (%), determined from the fast component of excess post-exercise oxygen consumption (EPOC) during recovery.
Measured: During the 5-minute post-exercise recovery period
Glycolytic Energy System Contribution (Absolute)
Evaluation of glycolytic energy system contribution in absolute terms (kJ), estimated using delta blood lactate concentration (Δ[BLa]) measured pre-test and post-test.
Measured: Pre-test and at the 5-minute post-test recovery
Glycolytic Energy System Contribution (Relative)
Evaluation of glycolytic energy system contribution in relative terms (%), estimated using delta blood lactate concentration (Δ[BLa]) measured pre-test and post-test.
Measured: Pre-test and at the 5-minute post-test recovery
Oxidative Energy System Contribution (Absolute)
Evaluation of oxidative energy system contribution in absolute terms (kJ), calculated based on net oxygen volume consumed during the 30-second test (VO₂net).
Measured: During the 30-second Wingate anaerobic test
Oxidative Energy System Contribution (Relative)
Evaluation of oxidative energy system contribution in relative terms (%), calculated based on net oxygen volume consumed during the 30-second test (VO₂net).
Measured: During the 30-second Wingate anaerobic test
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted29 Oct 2026
- Study start11 Feb 2026
- Primary completion26 Feb 2026
- Study completion26 Feb 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Anaerobic PerformanceStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- None (open label)
- Enrolment
- 11 participants (actual)
Sponsor and investigators
- Lead sponsor
- Manisa Celal Bayar University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07903714
- Sponsor's protocol ID
- MCBU_Energy System_324S917
- Other IDs
- 324S917
- Status last verified
- Oct 2026
- First submitted
- 14 Oct 2026
- Last updated
- 29 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 29 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Acute Effects of Hyperventilation, Post-Activation Performance Enhancement, and Combined Protocols on Anaerobic Capacity and Energy System Contributions
- ClinicalTrials.gov ID
- NCT07903714
- Acronym / sponsor ID
- MCBU_Energy System_324S917
- Conditions
- Anaerobic Performance, Energy System Contributions, Hyperventilation, Post Activation Potentiation
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 11 participants (actual)
- Lead sponsor
- Manisa Celal Bayar UniversityUniversity, hospital or other
- Study start
- 11 Feb 2026 (actual)
- Primary completion
- 26 Feb 2026 (actual)
- Study completion
- 26 Feb 2026 (actual)
- First posted
- 29 Oct 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of this study is to investigate the independent and combined effects of post-activation performance enhancement (PAPE) and voluntary hyperventilation (HV) interventions on anaerobic power outputs, energy system contributions during a 30-second Wingate Anaerobic Test (WAnT).
Study design
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- None (open label)
- Number of arms
- 4
| Arm | Type | Receives |
|---|---|---|
| Control Session | Active comparator | Procedure: Wingate Anaerobic TestBaseline 30-s Wingate test without prior intervention. |
| Hyperventilation (HV) Session | Experimental | Other: Voluntary Hyperventilation, Procedure: Wingate Anaerobic Test30-s Wingate test preceded by voluntary hyperventilation. |
| PAPE Session | Experimental | Other: Post-Activation Performance Enhancement (PAPE), Procedure: Wingate Anaerobic Test30-s Wingate test preceded by PAPE protocol. |
| PAPE+HV Session | Experimental | Other: Voluntary Hyperventilation, Other: Post-Activation Performance Enhancement (PAPE), Procedure: Wingate Anaerobic Test30-s Wingate test preceded by combined PAPE and hyperventilation protocols. |
Who may qualify
- Ages
- 18 to 25 years
- Sex
- Male only
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (0 listed)
Key exclusion criteria (3 listed)
- Current or recent orthopedic injuries that could negatively affect cycling performance
- Use of dietary supplements or performance-enhancing substances (e.g., creatine, caffeine, or bicarbonate) within the past four weeks
- Ongoing medical treatment that could affect metabolic or performance outcomes
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Voluntary HyperventilationControlled breathing protocol performed prior to testing. | Other | Hyperventilation (HV) Session, PAPE+HV Session |
| Post-Activation Performance Enhancement (PAPE)Conditioning protocol applied prior to the Wingate test to potentiate subsequent anaerobic performance. | Other | PAPE Session, PAPE+HV Session |
| Wingate Anaerobic Test30-second maximal anaerobic cycling test on a cycle ergometer. | Procedure or surgery | Control Session, Hyperventilation (HV) Session, PAPE Session, PAPE+HV Session |
Primary outcome
Relative Peak Power (RPP)
Time frame: During the 30-second Wingate anaerobic test
Evaluation of relative peak power during the 30-second Wingate anaerobic test
Relative Mean Power (RMP)
Time frame: During the 30-second Wingate anaerobic test
Evaluation of relative mean power during the 30-second Wingate anaerobic test.
Fatigue Index (FI)
Time frame: During the 30-second Wingate anaerobic test
Evaluation of fatigue index during the 30-second Wingate anaerobic test.
6 secondary outcomes
ATP-PCr Energy System Contribution (Absolute)
Time frame: During the 5-minute post-exercise recovery period
ATP-PCr Energy System Contribution (Relative)
Time frame: During the 5-minute post-exercise recovery period
Glycolytic Energy System Contribution (Absolute)
Time frame: Pre-test and at the 5-minute post-test recovery
Glycolytic Energy System Contribution (Relative)
Time frame: Pre-test and at the 5-minute post-test recovery
Oxidative Energy System Contribution (Absolute)
Time frame: During the 30-second Wingate anaerobic test
Oxidative Energy System Contribution (Relative)
Time frame: During the 30-second Wingate anaerobic test
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 29 Oct 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Voluntary Hyperventilation, Post-Activation Performance Enhancement (PAPE) and Wingate Anaerobic Test in people with Anaerobic Performance and Energy System Contributions, run by Manisa Celal Bayar University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 0 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 29 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Relative Peak Power (RPP) (time frame: During the 30-second Wingate anaerobic test). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 29 Oct 2026.