Lumbar RadiculopathyNCT07912073
Comparative Effects of Kinetic Control Training and Neural Mobilization in Lumbar Radiculopathy
A study testing Neural mobilization technique in people with Lumbar Radiculopathy, run by University of Management and Technology Lahore at 1 site in Pakistan.
Trial summary
Radiculopathy is a neuromusculoskeletal disorder characterized by compression or irritation of a spinal nerve root, resulting in pain, reduced range of motion, sensory disturbances, muscle weakness, and functional disability. Read more about this study
- Who is it for?
- Ages 25 to 50 years
- Conditions the study is for
- Lumbar Radiculopathy
- What is being tested?
- Neural mobilization technique
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 34 participants
- Where
- 1 sitePakistan
- Study dates
- 23 Oct 2026to 31 Dec 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 25 to 50 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- o lumbar disc prolapses (mild to moderate posterior and postrolateral disc bulge at the levels of L4-L5/L5-S1). Proven clinically by the neurological examination and MR
- Both genders.
- Age of 25-50 year
- Pain duration of more than three months
- Participants with NPRS less than 7 score will be included(11)
- Participants with RODI scale less than and equal to 30% score will be included(12)
Who cannot join
- o Piriformis syndrome
- Spinal tumors
- Lumbar instability caused by structural problem (e.g., ligament tear or spondylolistheses),
- History of any spinal surgery,
- Auto-immune disorders,
- Gynecological problems causing LBP in females (e.g., retroverted uterus or uterine congestion),
- Psychological problems interfering with the patient understanding of the orders,
- Renal problems
Trial locations and contacts
1 site in 1 country.
Pakistan1 site
University of Management & Technology
Lahore, Punjab Province, 54000
About this study
Official title: Comparative Effects of Kinetic Control Training and Neural Mobilization on Pain, Range of Motion and Disability Among Patients With Lumbar Radiculopathy.
Radiculopathy is a neuromusculoskeletal disorder characterized by compression or irritation of a spinal nerve root, resulting in pain, reduced range of motion, sensory disturbances, muscle weakness, and functional disability. It commonly affects the cervical and lumbar regions and can significantly impair daily activities and quality of life. Various physiotherapy interventions have been used to manage radiculopathy, including exercise therapy, manual therapy, neural mobilization, and motor control training. However, the most effective intervention for improving pain, mobility, and functional outcomes remains unclear, highlighting the need for further research.
Kinetic Control (KC) Training focus on identifying and correcting faulty movement patterns through motor control retraining and postural correction, thereby reducing mechanical stress on the affected structures. Neural Mobilization (NM) aims to restore the normal mobility and physiological function of neural tissues, decrease neural mechanosensitivity, and improve nerve movement within surrounding tissues.
Read more
The objective of this study is to compare the effects of Kinetic Control techniques and Neural Mobilization on pain, range of motion, and disability among patients with radiculopathy. The study will be conducted as a randomized clinical trial. Participants will be recruited using non-probability convenience sampling and will be randomly allocated into two groups. Group A will receive Kinetic Control s, while Group B will receive Neural Mobilization. Both groups will receive conventional physiotherapy treatment, including hot pack, TENS application for 20 minutes before intervention.
The treatment protocol will consist of 12 sessions over a period of 4 weeks. Outcome measures will be assessed at baseline, the 2nd week, and the 4th week. Pain intensity will be measured using the Numeric pain rating scale (NPRS), range of motion will be assessed using Bubble Inclinometer, and disability will be evaluated using the Revised Oswestry Disability Index (RODI) for lumbar radiculopathy. Data will be analyzed using SPSS version 24. The findings of this study may provide evidence regarding the comparative effectiveness of Kinetic Control training and Neural Mobilization technique in improving clinical outcomes among patients with radiculopathy.
- Conditions
- Lumbar Radiculopathy
- Being tested
- kinetic control training with conventional physical therapy, Neural mobilization technique
- Keywords
- low back pain, Kinetic control, Range of motion, Radiculopathy
- Medical subject headings
- Radiculopathy, Low Back Pain
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
kinetic control training with conventional physical therapyOther
For flexion control retraining, the patient is positioned in kneeling position with feet outside the bed. Then, he/she is asked to perform knees flexion over 90º with no flexion of the lumbar spine. Exercise is done for two consecutive minutes. The performed exercises in the session will be repeated as a home program, twice daily
Neural mobilization techniqueOther
The therapist applied hip flexion with simultaneous dorsiflexion and planter flexion of the patient's foot.
The sciatic neural glide is performed from 15º to 90º of hip flexion, 20-30 repetitions for 1-2 sets.
| Study group | Role | What they receive |
|---|---|---|
| kinetic control training with conventional physical therapy | Experimental | For flexion control retraining, the patient is positioned in kneeling position with feet outside the bed. Then, he/she is asked to perform knees flexion over 90º with no flexion of the lumbar spine. Exercise is done for two consecutive minutes. The performed exercises in the session will be repeated as a home program, twice daily Receives: Other: kinetic control training with conventional physical therapy |
| Neural mobilization technique with conventional physical therapy | Active comparator | The therapist applied hip flexion with simultaneous dorsiflexion and planter flexion of the patient's foot.
The sciatic neural glide is performed from 15º to 90º of hip flexion, 20-30 repetitions for 1-2 sets. Receives: Other: Neural mobilization technique |
What is being measured
The primary outcome is the main question the study is designed to answer.
Pain measured by Numeric Rating Scale (NPRS)
Numeric Rating Scale (NPRS) is most frequently used instruments to measure pain intensity in low back pain (LBP).The 11-point numeric with 0 representing No pain, 1-3 representing Mild Pain (nagging, annoying, interfering little with ADLs), 4-6 representing Moderate Pains (interferes significantly with ADLs), 7-10 representing Sever Pain (disabling, unable to perform ADLs(13)
Measured: At baseline and after 6 weeks
ROM MEASURED BY BUBBLE INCLINOMETER
The spinous process of the 1st sacral vertebra and the 12th thoracic vertebra were considered as reference points for measuring the range of motion in bending forward and backward. The spinous process of the 12th thoracic vertebra was considered as reference point for measuring the range of motion of lumbar side flexion. Two bubble inclinometers were used simultaneously for measuring the lumbar range of motion when bending forward (in the standing position), and one bubble inclinometer for measuring the lumbar range of motion for back extension (in the standing) and side flexion (in the standing position).
Measured: At baseline and after 6 weeks
DISABILITY MEASURED WITH REVISED OSWESTERY DISABILITY INDEX (RODQ)
The Oswestry Disability Index (also known as the Oswestry Low Back Pain Disability Questionnaire) is an extremely important tool that researchers and disability evaluators use to measure a patient's permanent functional disability. The test is considered the 'gold standard' of low back functional outcome tools. This scale contain question related to functional activities of pain intensity, personal care, lifting, walking, sitting, standing, sleeping, sex life, social life and travelling. For patients understanding, URDU version is used. Interpretation of scale are 0% to 20% for minimal disability, 21% to 40% for moderate disability, 41 % to 60 % for severe disability 61% to 80 % for crippled and 81 % to 100 %.(14)
Measured: At baseline and after 6 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted3 Nov 2026
- Study start23 Oct 2026
- Primary completion31 Dec 2026 (estimated)
- Study completion31 Dec 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Lumbar RadiculopathyStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 34 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Management and Technology Lahore
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Nosheen Manzoor, University of Management and Technology Lahore
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07912073
- Sponsor's protocol ID
- RE-208-2026
- Status last verified
- Oct 2026
- First submitted
- 27 Oct 2026
- Last updated
- 3 Nov 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: The results data collected , de-identified individual participant data will be shared.
Study at a glance
From the registry record, last updated by the sponsor on 3 Nov 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparative Effects of Kinetic Control Training and Neural Mobilization on Pain, Range of Motion and Disability Among Patients With Lumbar Radiculopathy.
- ClinicalTrials.gov ID
- NCT07912073
- Acronym / sponsor ID
- RE-208-2026
- Conditions
- Lumbar Radiculopathy
- Keywords
- low back pain, Kinetic control, Range of motion, Radiculopathy
- Study type
- Interventional
- Recruitment status
- Active, not recruiting
- Enrolment
- 34 participants (actual)
- Lead sponsor
- University of Management and Technology LahoreUniversity, hospital or other
- Study start
- 23 Oct 2026 (actual)
- Primary completion
- 31 Dec 2026 (estimated)
- Study completion
- 31 Dec 2026 (estimated)
- First posted
- 3 Nov 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Radiculopathy is a neuromusculoskeletal disorder characterized by compression or irritation of a spinal nerve root, resulting in pain, reduced range of motion, sensory disturbances, muscle weakness, and functional disability. It commonly affects the cervical and lumbar regions and can significantly impair daily activities and quality of life. Various physiotherapy interventions have been used to manage radiculopathy, including exercise therapy, manual therapy, neural mobilization, and motor control training. However, the most effective intervention for improving pain, mobility, and functional outcomes remains unclear, highlighting the need for further research.
Kinetic Control (KC) Training focus on identifying and correcting faulty movement patterns through motor control retraining and postural correction, thereby reducing mechanical stress on the affected structures. Neural Mobilization (NM) aims to restore the normal mobility and physiological function of neural tissues, decrease neural mechanosensitivity, and improve nerve movement within surrounding tissues.
The objective of this study is to compare the effects of Kinetic Control techniques and Neural Mobilization on pain, range of motion, and disability among patients with radiculopathy. The study will be conducted as a randomized clinical trial. Participants will be recruited using non-probability convenience sampling and will be randomly allocated into two groups. Group A will receive Kinetic Control s, while Group B will receive Neural Mobilization. Both groups will receive conventional physiotherapy treatment, including hot pack, TENS application for 20 minutes before intervention.
The treatment protocol will consist of 12 sessions over a period of 4 weeks. Outcome measures will be assessed at baseline, the 2nd week, and the 4th week. Pain intensity will be measured using the Numeric pain rating scale (NPRS), range of motion will be assessed using Bubble Inclinometer, and disability will be evaluated using the Revised Oswestry Disability Index (RODI) for lumbar radiculopathy. Data will be analyzed using SPSS version 24. The findings of this study may provide evidence regarding the comparative effectiveness of Kinetic Control training and Neural Mobilization technique in improving clinical outcomes among patients with radiculopathy.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| kinetic control training with conventional physical therapy | Experimental | Other: kinetic control training with conventional physical therapyFor flexion control retraining, the patient is positioned in kneeling position with feet outside the bed. Then, he/she is asked to perform knees flexion over 90º with no flexion of the lumbar spine. Exercise is done for two consecutive minutes. The performed exercises in the session will be repeated as a home program, twice daily |
| Neural mobilization technique with conventional physical therapy | Active comparator | Other: Neural mobilization techniqueThe therapist applied hip flexion with simultaneous dorsiflexion and planter flexion of the patient's foot. The sciatic neural glide is performed from 15º to 90º of hip flexion, 20-30 repetitions for 1-2 sets. |
Who may qualify
- Ages
- 25 to 50 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (6 listed)
- o lumbar disc prolapses (mild to moderate posterior and postrolateral disc bulge at the levels of L4-L5/L5-S1). Proven clinically by the neurological examination and MR
Key exclusion criteria (8 listed)
- o Piriformis syndrome
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| kinetic control training with conventional physical therapyFor flexion control retraining, the patient is positioned in kneeling position with feet outside the bed. Then, he/she is asked to perform knees flexion over 90º with no flexion of the lumbar spine. Exercise is done for two consecutive minutes. The performed exercises in the session will be repeated as a home program, twice daily | Other | kinetic control training with conventional physical therapy |
| Neural mobilization techniqueThe therapist applied hip flexion with simultaneous dorsiflexion and planter flexion of the patient's foot. The sciatic neural glide is performed from 15º to 90º of hip flexion, 20-30 repetitions for 1-2 sets. | Other | Neural mobilization technique with conventional physical therapy |
Primary outcome
Pain measured by Numeric Rating Scale (NPRS)
Time frame: At baseline and after 6 weeks
Numeric Rating Scale (NPRS) is most frequently used instruments to measure pain intensity in low back pain (LBP).The 11-point numeric with 0 representing No pain, 1-3 representing Mild Pain (nagging, annoying, interfering little with ADLs), 4-6 representing Moderate Pains (interferes significantly with ADLs), 7-10 representing Sever Pain (disabling, unable to perform ADLs(13)
ROM MEASURED BY BUBBLE INCLINOMETER
Time frame: At baseline and after 6 weeks
The spinous process of the 1st sacral vertebra and the 12th thoracic vertebra were considered as reference points for measuring the range of motion in bending forward and backward. The spinous process of the 12th thoracic vertebra was considered as reference point for measuring the range of motion of lumbar side flexion. Two bubble inclinometers were used simultaneously for measuring the lumbar range of motion when bending forward (in the standing position), and one bubble inclinometer for measuring the lumbar range of motion for back extension (in the standing) and side flexion (in the standing position).
DISABILITY MEASURED WITH REVISED OSWESTERY DISABILITY INDEX (RODQ)
Time frame: At baseline and after 6 weeks
The Oswestry Disability Index (also known as the Oswestry Low Back Pain Disability Questionnaire) is an extremely important tool that researchers and disability evaluators use to measure a patient's permanent functional disability. The test is considered the 'gold standard' of low back functional outcome tools. This scale contain question related to functional activities of pain intensity, personal care, lifting, walking, sitting, standing, sleeping, sex life, social life and travelling. For patients understanding, URDU version is used. Interpretation of scale are 0% to 20% for minimal disability, 21% to 40% for moderate disability, 41 % to 60 % for severe disability 61% to 80 % for crippled and 81 % to 100 %.(14)
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 3 Nov 2026.
- Related InfoLink provided by the sponsor.
- Related InfoLink provided by the sponsor.
- Related InfoLink provided by the sponsor.
- Related InfoLink provided by the sponsor.
- Related InfoLink provided by the sponsor.
- Individual participant dataSharing planned: Yes. The results data collected , de-identified individual participant data will be shared.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Neural mobilization technique in people with Lumbar Radiculopathy, run by University of Management and Technology Lahore at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 3 Nov 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Pain measured by Numeric Rating Scale (NPRS) (time frame: At baseline and after 6 weeks). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 3 Nov 2026.