Self Injurious BehaviorNCT07913425
Examining the Effectiveness of a Brief Therapeutic Intervention for Reducing Self-Harm Among Adolescents
A study testing Cutting Down Program - a three-month cognitive-behavioral psychotherapy focused on reducing self-injury urges and behaviors in adolescents in people with Self Injurious Behavior and Self Injurious Behavior Without Suicidal Intent, run by University of Haifa at 1 site in Israel.
Trial summary
Non-suicidal self-injury (NSSI), defined as deliberate self-inflicted destruction of body tissue without intent to die, is particularly prevalent during mid-adolescence, with prevalence estimated around 16-22% in community samples. Although distinct from suicidality, NSSI is a strong predictor of suicidal attempts. Read more about this study
- Who is it for?
- Ages 12 to 18 years
- Conditions the study is for
- Self Injurious Behavior, Self Injurious Behavior Without Suicidal Intent
- What is being tested?
- Cutting Down Program - a three-month cognitive-behavioral psychotherapy focused on reducing self-injury urges and behaviors in adolescents
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 40 participants
- Where
- 1 siteIsrael
- Study dates
- 10 Nov 2026to 30 Sep 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 12 to 18 years
- All sexes
- No healthy volunteers
- Child, Adult
Who may be able to join
- At least one active self-injurious behavior during the past 6 months, prior to beginning of treatment.
- Both adolescent and participating parent are fluent in Hebrew
Who cannot join
- Active psychosis
- Substance use disorder
- Cognitive impairments precluding understanding of consent or research questions or adhering to the treatment.
- Altered levels of consciousness
- Linguistic limitations precluding understanding of consent or research questions or adhering to the treatment.
- Patients whose parents/legal guardians cannot comply with study requirements.
Show all 10Show fewer
- Necessity of psychiatric treatment due to depression/suicidality
- Severe suicidality (active suicidal intents)
- Severe depression
- A history of mental health diagnoses and/or hospitalizations.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Israel1 site
Psychological and Counseling Services (SHEFI)
Tel Aviv
Yael Shahar National Coordinator for Depression and Suicide Prevent, +972-50-744-0071, yaelshahars@gmail.com
About this study
Official title: Examining the Effectiveness of a Brief Therapeutic Intervention for Reducing Self-harm Among Adolescents
Non-suicidal self-injury (NSSI), defined as deliberate self-inflicted destruction of body tissue without intent to die, is particularly prevalent during mid-adolescence, with prevalence estimated around 16-22% in community samples. Although distinct from suicidality, NSSI is a strong predictor of suicidal attempts. Yet intervention studies addressing self-injury urges and behaviors in youth remain scarce. The Cutting Down Program (CDP) is currently one of the most promising interventions for adolescents who self-harm. This three-month intervention, evidenced in a randomized controlled trial, integrates techniques from cognitive-behavioral (CBT) and dialectic-behavioral (DBT) therapies. Recently, an updated CDP protocol was developed to more directly address suicidality and involve parents in the treatment. This study will test the updated protocol with a sample of adolescents who self-harm, recruited from schools and treated by educational psychologists of the Israeli Psychological and Counseling Services (SHEFI). We will examine the intervention's effects on mental health outcomes (e.g., self-injury) and on potential mediators (emotion regulation and parental emotion socialization), to clarify its mechanisms of change.
Read the detailed description
The intervention's effects will be assessed in a pilot sample of 40 adolescents aged 12-18. Adolescents identified by school counselors as engaging in self-injury will be referred to SHEFI nationwide, as part of routine assessment and treatment procedures. Twenty expert educational psychologists trained in the CDP will each treat two adolescents. Following an initial intake, the adapted CDP includes 14 weekly sessions over three months: 12 with the adolescent and 3 with the parents. A final follow-up session (session 15) will be held with the adolescent and their parents three months after the end of treatment. Adolescents and one parent (the same parent throughout) will complete self-report questionnaires at four time points: before treatment, after the second parent session (2 months), towards the end of treatment (3 months), and at follow-up (6 months).
All therapists in the study are expert educational psychologists. They will complete a two-day training led by the principal investigator (senior researcher and a clinical psychology experienced with the CDP) and an educational psychologist experienced in the CDP. Following this training, they will take part in year-long group supervision in small groups every two weeks, led by clinical or educational psychologists experienced with the CDP, which will serve as a space for consultation. All training and supervision will be conducted online to allow nationwide participation. Treatment sessions will take place in person at local SHEFI branches.
- Being tested
- Cutting Down Program - a three-month cognitive-behavioral psychotherapy focused on reducing self-injury urges and behaviors in adolescents
- Keywords
- self injury, suicidality, depressive symptoms, adolescents, emotion regulation, parental emotion socialization
- Medical subject headings
- Self-Injurious Behavior, Suicidal Ideation, Depression, Emotional Regulation
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Cutting Down Program - a three-month cognitive-behavioral psychotherapy focused on reducing self-injury urges and behaviors in adolescentsBehavioural
The CDP protocol in this project consists of 12 weekly individual 50-minute sessions, three parents sessions and one follow-up meeting with the family. Modules include: 1. Psychoeducation about self-injury, understanding personalized functions of self-injury, discussing motivation for change, risk assessment for suicidality and safety plan. 2. Emotional identification and management, activities scheduling, identifying and managing negative thoughts and self-judgment, and committing to goals. 3. Coping strategies, including problem solving, assertiveness, management of anxiety, anger or hopelessness, mindfulness, emotion regulation and alternatives for self-injury. 4. Progress review, identifying triggers and reinforcing coping strategies to maintain progress and post-treatment. Parents meetings focus on psychoeducation about self-injury and skills for emotion validation and support of alternatives to self-injury. The third session involves both parents and adolescents, emphasizing pare
| Study group | Role | What they receive |
|---|---|---|
| Cutting Down Program | Experimental | Psychotherapeutic treatment Receives: Behavioral: Cutting Down Program - a three-month cognitive-behavioral psychotherapy focused on reducing self-injury urges and behaviors in adolescents |
What is being measured
The primary outcome is the main question the study is designed to answer.
Self injury behaviors
Deliberate Self-Harm Inventory (DSHI): A 6-item self-report assessing the frequency of different types of non-suicidal self-injury behaviors adapted for the last month. The items are rated from 1 (not at all) to 5 (5 times or more), with the request to enter the exact number of self harm behaviors if participant selected any option that is more than 1. The minimum sum score is 6, and the maximun depends on the exact number of self harm behaviors the participant reports, with higher number indicates higher fequency of non-suicidal self injurious behaviors.
The scale will also be administered one time before the beginning of the treatment asking about the last 6 months, using only the 1-5 item rating (min sum score: 6, max sum score: 30).
The version asking about the last month will be administered at four time points as described in the Time Frame.
Measured: (1) Before the first treatment meeting (2) 2 months after the treatment starts (after the 2nd parent session), (3) 3 months after the treatment starts (towards the end of the treatment), (4) 3 months after the end of the treatment (follow up).
Self injury thoughts
Alexian Brothers Urge to Self-Injure Scale (ABUSI). A 5-item self-report addressing frequency and intensity of urges to self-injure in the past week. Each item is rated from 1 (not at all) to 7 (almost all the time/strong intensity of urges). The minimal sum score is 5 and the maximal is 35, with higher scores indicating higher frequency and intensity of urges to self-injure.
Measured: (1) Before the first treatment meeting (2) 2 months after the treatment starts (after the 2nd parent session), (3) 3 months after the treatment starts (towards the end of the treatment), (4) 3 months after the end of the treatment (follow up).
Secondary outcomes (4)
Suicidal thoughts and behaviors
Columbia Suicide Severity Rating Scale, Child Version (C-SSRS). A 7-item self-report assessing incidence and severity of suicidal thoughts and behaviors. The first six items, scored as 0 (no) or 1 (yes), ask about the last two weeks, and the seventh item is an open question asking about the number of suicidal behaviors in the last month. The scale's score is the highest item endorsed among the first six items. Minimum score is 0 and maximum score is 6, with higher score indicating greater severity of suicidal thoughts and behaviors.
Measured: (1) Before the first treatment meeting (2) 2 months after the treatment starts (after the 2nd parent session), (3) 3 months after the treatment starts (towards the end of the treatment), (4) 3 months after the end of the treatment (follow up).
Depressive symptoms
Short Mood and Feelings Questionnaire (SMFQ); A 13-item self report assessing the the respondent's recent feelings and behaviors, focusing on depressive symptoms in the last two weeks. Each item is rated from 0 (untrue) to 2 (true). The sum score can range from 0 to 26, with higher score indicating more depressive symptoms.
Measured: (1) Before the first treatment meeting (2) 2 months after the treatment starts (after the 2nd parent session), (3) 3 months after the treatment starts (towards the end of the treatment), (4) 3 months after the end of the treatment (follow up).
Emotion dysregulation
Difficulties in Emotion Regulation Scale (DERS) - short version. An 18-item self-report assessing difficulties in regulating emotional distress. Key dimensions include nonacceptance of emotions, and difficulties in goal-directed behavior, impulse control, emotion awareness and clarity, and in use of regulation strategies. Each item is rated from 1 (almost never) to 5 (almost always). The sum score can range from 18 to 90, with higher score indicating more emotion dysregulation.
Measured: (1) Before the first treatment meeting (2) 2 months after the treatment starts (after the 2nd parent session), (3) 3 months after the treatment starts (towards the end of the treatment), (4) 3 months after the end of the treatment (follow up).
Parental emotion socialization
Coping with Children's Negative Emotions Scale, measured in two versions: a. Adolescents' Perceptions of Parent (CCNES-APP). b. CCNES-A parent's perception. Each version includes the same nine scenarios depicting adolescents' emotional distress, for which respondents select the parent's responses. Responses range from validating, expressive encouragement, emotion- focus reactions and problem-focus reactions, to distress , minimizing or punitive reactions. There are seven possible parental responses to each of the 9 scenarios, with each response rated from 1 (very unlikely) to 7 (very likely). The final score is divided into two average scores: supportive responses and unsupportive responses. Each score can range from 1 to 7, with higher score indicating greater likelihood that parents use this type of responses. Parents and adolescent versions will be computed separately to create distinct informant scores on parental emotion socialization.
Measured: (1) Before the first treatment meeting (2) 2 months after the treatment starts (after the 2nd parent session), (3) 3 months after the treatment starts (towards the end of the treatment), (4) 3 months after the end of the treatment (follow up).
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted3 Nov 2026
- Study start10 Nov 2026 (estimated)
- Primary completion30 Jun 2027 (estimated)
- Study completion30 Sep 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (8)Papers the sponsor has linked to this study.
- Other trials for Self Injurious BehaviorStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Model description
- Single-arm pre-post design with a three-month follow-up
- Masking
- None (open label)
- Enrolment
- 40 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of Haifa
- Sponsor type
- University, hospital or other
- Collaborators
- Psychological and Counseling Services (SHEFI)
- Responsible party
- Sponsor
- Investigators
- Adva Eichengreen, PhD, Principal investigator, University of Haifa
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07913425
- Sponsor's protocol ID
- 083-25
- Status last verified
- Nov 2026
- First submitted
- 26 Oct 2026
- Last updated
- 3 Nov 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: Only IPD used in the results publication - upon request or through the university repository. Study design and planned statistical analyses will be registered in OSF on Nov. 2026
Publications
Plener PL, Schumacher TS, Munz LM, Groschwitz RC. The longitudinal course of non-suicidal self-injury and deliberate self-harm: a systematic review of the literature. Borderline Personal Disord Emot Dysregul. 2015 Jan 30;2:2. doi: 10.1186/s40479-014-0024-3. eCollection 2015.
PubMed 26401305Ohlis A, Li L, Kuja-Halkola R, Lundstrom S, D'Onofrio BM, Hellner C, Lichtenstein P, Cederlof M, Chang Z, Bjureberg J. Genetic and environmental aetiologies of the transition from nonsuicidal self-injury to suicide attempt: a longitudinal twin study. Mol Psychiatry. 2025 Dec;30(12):5828-5832. doi: 10.1038/s41380-025-03165-z. Epub 2025 Aug 22.
PubMed 40847004Moloney F, Amini J, Sinyor M, Schaffer A, Lanctot KL, Mitchell RHB. Sex Differences in the Global Prevalence of Nonsuicidal Self-Injury in Adolescents: A Meta-Analysis. JAMA Netw Open. 2024 Jun 3;7(6):e2415436. doi: 10.1001/jamanetworkopen.2024.15436.
PubMed 38874927Farkas BF, Takacs ZK, Kollarovics N, Balazs J. The prevalence of self-injury in adolescence: a systematic review and meta-analysis. Eur Child Adolesc Psychiatry. 2024 Oct;33(10):3439-3458. doi: 10.1007/s00787-023-02264-y. Epub 2023 Jul 24.
PubMed 37486387Clareus B, Lundh LG, Wangby-Lundh M, Bjarehed J, Daukantaite D. Time trends in non-suicidal self-injury, disordered eating, and mental health problems between 2007 and 2025: a comparison of two Swedish adolescent cohorts. Eur Child Adolesc Psychiatry. 2026 Oct;35(10):3325-3334. doi: 10.1007/s00787-026-03105-4. Epub 2026 Jun 22.
PubMed 42329373Taylor, L., Simic, M., & Schmidt, U. (2022). Cutting Down: An Evidence-based CBT Workbook for Treating Young People Who Self-Harm. Routledge.
Kaess M, Edinger A, Fischer-Waldschmidt G, Parzer P, Brunner R, Resch F. Effectiveness of a brief psychotherapeutic intervention compared with treatment as usual for adolescent nonsuicidal self-injury: a single-centre, randomised controlled trial. Eur Child Adolesc Psychiatry. 2020 Jun;29(6):881-891. doi: 10.1007/s00787-019-01399-1. Epub 2019 Sep 11.
PubMed 31512050Taylor LM, Oldershaw A, Richards C, Davidson K, Schmidt U, Simic M. Development and pilot evaluation of a manualized cognitive-behavioural treatment package for adolescent self-harm. Behav Cogn Psychother. 2011 Oct;39(5):619-25. doi: 10.1017/S1352465811000075. Epub 2011 Mar 11.
PubMed 21392417
Study at a glance
From the registry record, last updated by the sponsor on 3 Nov 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Examining the Effectiveness of a Brief Therapeutic Intervention for Reducing Self-harm Among Adolescents
- ClinicalTrials.gov ID
- NCT07913425
- Acronym / sponsor ID
- 083-25
- Keywords
- self injury, suicidality, depressive symptoms, adolescents, emotion regulation, parental emotion socialization
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 40 participants (estimated)
- Lead sponsor
- University of HaifaUniversity, hospital or other
- Collaborators
- Psychological and Counseling Services (SHEFI)
- Study start
- 10 Nov 2026 (estimated)
- Primary completion
- 30 Jun 2027 (estimated)
- Study completion
- 30 Sep 2027 (estimated)
- First posted
- 3 Nov 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Non-suicidal self-injury (NSSI), defined as deliberate self-inflicted destruction of body tissue without intent to die, is particularly prevalent during mid-adolescence, with prevalence estimated around 16-22% in community samples. Although distinct from suicidality, NSSI is a strong predictor of suicidal attempts. Yet intervention studies addressing self-injury urges and behaviors in youth remain scarce. The Cutting Down Program (CDP) is currently one of the most promising interventions for adolescents who self-harm. This three-month intervention, evidenced in a randomized controlled trial, integrates techniques from cognitive-behavioral (CBT) and dialectic-behavioral (DBT) therapies. Recently, an updated CDP protocol was developed to more directly address suicidality and involve parents in the treatment. This study will test the updated protocol with a sample of adolescents who self-harm, recruited from schools and treated by educational psychologists of the Israeli Psychological and Counseling Services (SHEFI). We will examine the intervention's effects on mental health outcomes (e.g., self-injury) and on potential mediators (emotion regulation and parental emotion socialization), to clarify its mechanisms of change.
Detailed description
The intervention's effects will be assessed in a pilot sample of 40 adolescents aged 12-18. Adolescents identified by school counselors as engaging in self-injury will be referred to SHEFI nationwide, as part of routine assessment and treatment procedures. Twenty expert educational psychologists trained in the CDP will each treat two adolescents. Following an initial intake, the adapted CDP includes 14 weekly sessions over three months: 12 with the adolescent and 3 with the parents. A final follow-up session (session 15) will be held with the adolescent and their parents three months after the end of treatment. Adolescents and one parent (the same parent throughout) will complete self-report questionnaires at four time points: before treatment, after the second parent session (2 months), towards the end of treatment (3 months), and at follow-up (6 months).
All therapists in the study are expert educational psychologists. They will complete a two-day training led by the principal investigator (senior researcher and a clinical psychology experienced with the CDP) and an educational psychologist experienced in the CDP. Following this training, they will take part in year-long group supervision in small groups every two weeks, led by clinical or educational psychologists experienced with the CDP, which will serve as a space for consultation. All training and supervision will be conducted online to allow nationwide participation. Treatment sessions will take place in person at local SHEFI branches.
Study design
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
- Model description
- Single-arm pre-post design with a three-month follow-up
| Arm | Type | Receives |
|---|---|---|
| Cutting Down Program | Experimental | Behavioral: Cutting Down Program - a three-month cognitive-behavioral psychotherapy focused on reducing self-injury urges and behaviors in adolescentsPsychotherapeutic treatment |
Who may qualify
- Ages
- 12 to 18 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult
Key inclusion criteria (2 listed)
- At least one active self-injurious behavior during the past 6 months, prior to beginning of treatment.
- Both adolescent and participating parent are fluent in Hebrew
Key exclusion criteria (10 listed)
- Active psychosis
- Substance use disorder
- Cognitive impairments precluding understanding of consent or research questions or adhering to the treatment.
- Altered levels of consciousness
- Linguistic limitations precluding understanding of consent or research questions or adhering to the treatment.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Cutting Down Program - a three-month cognitive-behavioral psychotherapy focused on reducing self-injury urges and behaviors in adolescentsThe CDP protocol in this project consists of 12 weekly individual 50-minute sessions, three parents sessions and one follow-up meeting with the family. Modules include: 1. Psychoeducation about self-injury, understanding personalized functions of self-injury, discussing motivation for change, risk assessment for suicidality and safety plan. 2. Emotional identification and management, activities scheduling, identifying and managing negative thoughts and self-judgment, and committing to goals. 3. Coping strategies, including problem solving, assertiveness, management of anxiety, anger or hopelessness, mindfulness, emotion regulation and alternatives for self-injury. 4. Progress review, identifying triggers and reinforcing coping strategies to maintain progress and post-treatment. Parents meetings focus on psychoeducation about self-injury and skills for emotion validation and support of alternatives to self-injury. The third session involves both parents and adolescents, emphasizing pare | Behavioural | Cutting Down Program |
Primary outcome
Self injury behaviors
Time frame: (1) Before the first treatment meeting (2) 2 months after the treatment starts (after the 2nd parent session), (3) 3 months after the treatment starts (towards the end of the treatment), (4) 3 months after the end of the treatment (follow up).
Deliberate Self-Harm Inventory (DSHI): A 6-item self-report assessing the frequency of different types of non-suicidal self-injury behaviors adapted for the last month. The items are rated from 1 (not at all) to 5 (5 times or more), with the request to enter the exact number of self harm behaviors if participant selected any option that is more than 1. The minimum sum score is 6, and the maximun depends on the exact number of self harm behaviors the participant reports, with higher number indicates higher fequency of non-suicidal self injurious behaviors. The scale will also be administered one time before the beginning of the treatment asking about the last 6 months, using only the 1-5 item rating (min sum score: 6, max sum score: 30). The version asking about the last month will be administered at four time points as described in the Time Frame.
Self injury thoughts
Time frame: (1) Before the first treatment meeting (2) 2 months after the treatment starts (after the 2nd parent session), (3) 3 months after the treatment starts (towards the end of the treatment), (4) 3 months after the end of the treatment (follow up).
Alexian Brothers Urge to Self-Injure Scale (ABUSI). A 5-item self-report addressing frequency and intensity of urges to self-injure in the past week. Each item is rated from 1 (not at all) to 7 (almost all the time/strong intensity of urges). The minimal sum score is 5 and the maximal is 35, with higher scores indicating higher frequency and intensity of urges to self-injure.
4 secondary outcomes
Suicidal thoughts and behaviors
Time frame: (1) Before the first treatment meeting (2) 2 months after the treatment starts (after the 2nd parent session), (3) 3 months after the treatment starts (towards the end of the treatment), (4) 3 months after the end of the treatment (follow up).
Depressive symptoms
Time frame: (1) Before the first treatment meeting (2) 2 months after the treatment starts (after the 2nd parent session), (3) 3 months after the treatment starts (towards the end of the treatment), (4) 3 months after the end of the treatment (follow up).
Emotion dysregulation
Time frame: (1) Before the first treatment meeting (2) 2 months after the treatment starts (after the 2nd parent session), (3) 3 months after the treatment starts (towards the end of the treatment), (4) 3 months after the end of the treatment (follow up).
Parental emotion socialization
Time frame: (1) Before the first treatment meeting (2) 2 months after the treatment starts (after the 2nd parent session), (3) 3 months after the treatment starts (towards the end of the treatment), (4) 3 months after the end of the treatment (follow up).
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 3 Nov 2026.
- Background: PubMed 26401305Plener PL, Schumacher TS, Munz LM, Groschwitz RC. The longitudinal course of non-suicidal self-injury and deliberate self-harm: a systematic review of the literature. Borderline Personal Disord Emot Dysregul. 2015 Jan 30;2:2. doi: 10.1186/s40479-014-0024-3. eCollection 2015.
- Background: PubMed 40847004Ohlis A, Li L, Kuja-Halkola R, Lundstrom S, D'Onofrio BM, Hellner C, Lichtenstein P, Cederlof M, Chang Z, Bjureberg J. Genetic and environmental aetiologies of the transition from nonsuicidal self-injury to suicide attempt: a longitudinal twin study. Mol Psychiatry. 2025 Dec;30(12):5828-5832. doi: 10.1038/s41380-025-03165-z. Epub 2025 Aug 22.
- Background: PubMed 38874927Moloney F, Amini J, Sinyor M, Schaffer A, Lanctot KL, Mitchell RHB. Sex Differences in the Global Prevalence of Nonsuicidal Self-Injury in Adolescents: A Meta-Analysis. JAMA Netw Open. 2024 Jun 3;7(6):e2415436. doi: 10.1001/jamanetworkopen.2024.15436.
- Background: PubMed 37486387Farkas BF, Takacs ZK, Kollarovics N, Balazs J. The prevalence of self-injury in adolescence: a systematic review and meta-analysis. Eur Child Adolesc Psychiatry. 2024 Oct;33(10):3439-3458. doi: 10.1007/s00787-023-02264-y. Epub 2023 Jul 24.
- Background: PubMed 42329373Clareus B, Lundh LG, Wangby-Lundh M, Bjarehed J, Daukantaite D. Time trends in non-suicidal self-injury, disordered eating, and mental health problems between 2007 and 2025: a comparison of two Swedish adolescent cohorts. Eur Child Adolesc Psychiatry. 2026 Oct;35(10):3325-3334. doi: 10.1007/s00787-026-03105-4. Epub 2026 Jun 22.
- BackgroundTaylor, L., Simic, M., & Schmidt, U. (2022). Cutting Down: An Evidence-based CBT Workbook for Treating Young People Who Self-Harm. Routledge.
- Background: PubMed 31512050Kaess M, Edinger A, Fischer-Waldschmidt G, Parzer P, Brunner R, Resch F. Effectiveness of a brief psychotherapeutic intervention compared with treatment as usual for adolescent nonsuicidal self-injury: a single-centre, randomised controlled trial. Eur Child Adolesc Psychiatry. 2020 Jun;29(6):881-891. doi: 10.1007/s00787-019-01399-1. Epub 2019 Sep 11.
- Background: PubMed 21392417Taylor LM, Oldershaw A, Richards C, Davidson K, Schmidt U, Simic M. Development and pilot evaluation of a manualized cognitive-behavioural treatment package for adolescent self-harm. Behav Cogn Psychother. 2011 Oct;39(5):619-25. doi: 10.1017/S1352465811000075. Epub 2011 Mar 11.
- Individual participant dataSharing planned: Yes. Only IPD used in the results publication - upon request or through the university repository. Study design and planned statistical analyses will be registered in OSF on Nov. 2026
Related trials for Self Injurious Behavior
Not yet recruiting
A Pre-post Study of a Lethal Means Safety Planning Intervention for Youth at Elevated Suicide Risk in the Emergency Department
Suicidal Ideas, Suicidal Ideation
RecruitingObservational study
Student Precarity and Psychiatry
Depressive Disorder, Major, Generalized Anxiety Disorder
Not yet recruiting
SERENE Low-Intensity Focused Ultrasound for Cognitive Control
Suicidal Ideation, Cognitive Control
Not yet recruiting
A MRT to Optimize a JITAI for Alcohol Craving and Suicide Ideation
Alcohol Use Disorder (AUD), Suicide Ideation
Enrolling by invitation
Pilot Study of a Modified Safety Planning Intervention for Elementary School-Aged Children - Main Study
Suicidal Ideation, Suicidal Behaviors
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Adva Eichengreen, PhD principal investigator
University of Haifa
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Cutting Down Program - a three-month cognitive-behavioral psychotherapy focused on reducing self-injury urges and behaviors in adolescents in people with Self Injurious Behavior and Self Injurious Behavior Without Suicidal Intent, run by University of Haifa at 1 site in Israel.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 10 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 3 Nov 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Israel. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Adva Eichengreen, PhD (972-506044818, adva.eichengreen@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Self injury behaviors (time frame: (1) Before the first treatment meeting (2) 2 months after the treatment starts (after the 2nd parent session), (3) 3 months after the treatment starts (towards the end of the treatment), (4) 3 months after the end of the treatment (follow up).). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07913425, which also lists 8 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 3 Nov 2026.